Tešić, Živoslav

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Authority KeyName Variants
orcid::0000-0002-5162-3123
  • Tešić, Živoslav (29)
Projects
Structure-properties relationships of natural and synthetic molecules and their metal complexes Sinteza, analiza i aktivnost novih organskih polidentatnih liganada i njihovih kompleksa sa d-metalima
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200116 (University of Belgrade, Faculty of Agriculture)
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM)
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200051 (Institute of General and Physical Chemistry, Belgrade) Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200288 (Innovation Center of the Faculty of Chemistry)
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200134 (University of Novi Sad, Faculty of Technology) Ministry of Science, Technology and Development of the Republic Serbia (Contract: No 1399)
Ministry of Science, Technology and Development of the Republic Serbia (Contract: No 1713) Reinforcement of the Faculty of Chemistry, University of Belgrade, towards becoming a Center of Excellence in the region of WB for Molecular Biotechnology and Food research
Ministry of Science, Technology and Development of the Republic Serbia (Contract: MHT.2.09.0022.B) European Union, contract No ICA2-CT-2002- 10001
European Union (ICA2-CT-2001-10037) European Union, Project “Prometeas” (Contract No ICA2-CT-2001-10037)
Synthesis, characterization and activity of organic and coordination composition and their application in (bio) nanotechnology Farmakodinamska i farmakogenetska istraživanja novih lekova i prediktivna/prognostička vrednost farmakoterapije u onkologiji
Slovenian Research Agency (research core funding No. P1-0005). The Research Council of Norway (Project No. 280376)

Author's Bibliography

Breakthrough Analysis of Chemical Composition and Applied Chemometrics of European Plum Cultivars Grown in Norway

Fotirić Akšić, Milica; Tešić, Živoslav; Kalaba, Milica; Ćirić, Ivanka; Pezo, Lato; Lončar, Biljana; Gašić, Uroš; Dojčinović, Biljana; Tosti, Tomislav; Meland, Mekjell

(MDPI, 2023)

TY  - JOUR
AU  - Fotirić Akšić, Milica
AU  - Tešić, Živoslav
AU  - Kalaba, Milica
AU  - Ćirić, Ivanka
AU  - Pezo, Lato
AU  - Lončar, Biljana
AU  - Gašić, Uroš
AU  - Dojčinović, Biljana
AU  - Tosti, Tomislav
AU  - Meland, Mekjell
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6351
AB  - The aim of this study was to find the chemical parameters for the differentiation of plum cultivars grown along the fjord areas of Western Norway and Eastern Norway, having specific agroclimatic conditions. Chemical analysis of the fruits confirmed the contents of 13 quantified elements, 22 sugar compounds, 11 organic acids, 19 phenolic compounds, and antioxidant activity in 68 plum cultivars. Dominated contents were noted for nitrogen (with the maximum mean value of 3.11%), potassium (8055.80 mg/kg), and phosphorous (7878.88 mg/kg). Averagely, the highest level of sugars was determined for glucose (244.46 g/kg), fructose (197.92 g/kg), sucrose (208.25 g/kg), and sorbitol (98.02 g/kg), organic acids for malic acid (24.06 g/kg), and for polyphenol compounds were 5-O-caffeoylquinic acid (66.31 mg/kg), and rutin (58.06 mg/kg). Applied principal component analysis has been useful for distinguishing the plum cultivars from three areas in Norway where copper, iron, potassium, magnesium, manganese, and sodium; sucrose, ribose, maltose, and raffinose; p-hydroxybenzoic acid, rutin, ferulic acid, kaempferol 7-O-glucoside, p-coumaric acid, and 5-O-caffeoylquinic acid were the most influential. In regard to human health and future breeding work that will have the aim to produce functional food with high health-related compounds, the plum cultivar ‘Mallard’ should be underlined due to the high level of elements, ‘Valor’ due to high sugar content, ‘Helgøyplomme’ due to content of organic acids, and ‘Diamond’ due to the content of phenolic compounds. © 2023 by the authors.
PB  - MDPI
T2  - Horticulturae
T1  - Breakthrough Analysis of Chemical Composition and Applied Chemometrics of European Plum Cultivars Grown in Norway
VL  - 9
IS  - 4
DO  - 10.3390/horticulturae9040477
ER  - 
@article{
author = "Fotirić Akšić, Milica and Tešić, Živoslav and Kalaba, Milica and Ćirić, Ivanka and Pezo, Lato and Lončar, Biljana and Gašić, Uroš and Dojčinović, Biljana and Tosti, Tomislav and Meland, Mekjell",
year = "2023",
abstract = "The aim of this study was to find the chemical parameters for the differentiation of plum cultivars grown along the fjord areas of Western Norway and Eastern Norway, having specific agroclimatic conditions. Chemical analysis of the fruits confirmed the contents of 13 quantified elements, 22 sugar compounds, 11 organic acids, 19 phenolic compounds, and antioxidant activity in 68 plum cultivars. Dominated contents were noted for nitrogen (with the maximum mean value of 3.11%), potassium (8055.80 mg/kg), and phosphorous (7878.88 mg/kg). Averagely, the highest level of sugars was determined for glucose (244.46 g/kg), fructose (197.92 g/kg), sucrose (208.25 g/kg), and sorbitol (98.02 g/kg), organic acids for malic acid (24.06 g/kg), and for polyphenol compounds were 5-O-caffeoylquinic acid (66.31 mg/kg), and rutin (58.06 mg/kg). Applied principal component analysis has been useful for distinguishing the plum cultivars from three areas in Norway where copper, iron, potassium, magnesium, manganese, and sodium; sucrose, ribose, maltose, and raffinose; p-hydroxybenzoic acid, rutin, ferulic acid, kaempferol 7-O-glucoside, p-coumaric acid, and 5-O-caffeoylquinic acid were the most influential. In regard to human health and future breeding work that will have the aim to produce functional food with high health-related compounds, the plum cultivar ‘Mallard’ should be underlined due to the high level of elements, ‘Valor’ due to high sugar content, ‘Helgøyplomme’ due to content of organic acids, and ‘Diamond’ due to the content of phenolic compounds. © 2023 by the authors.",
publisher = "MDPI",
journal = "Horticulturae",
title = "Breakthrough Analysis of Chemical Composition and Applied Chemometrics of European Plum Cultivars Grown in Norway",
volume = "9",
number = "4",
doi = "10.3390/horticulturae9040477"
}
Fotirić Akšić, M., Tešić, Ž., Kalaba, M., Ćirić, I., Pezo, L., Lončar, B., Gašić, U., Dojčinović, B., Tosti, T.,& Meland, M.. (2023). Breakthrough Analysis of Chemical Composition and Applied Chemometrics of European Plum Cultivars Grown in Norway. in Horticulturae
MDPI., 9(4).
https://doi.org/10.3390/horticulturae9040477
Fotirić Akšić M, Tešić Ž, Kalaba M, Ćirić I, Pezo L, Lončar B, Gašić U, Dojčinović B, Tosti T, Meland M. Breakthrough Analysis of Chemical Composition and Applied Chemometrics of European Plum Cultivars Grown in Norway. in Horticulturae. 2023;9(4).
doi:10.3390/horticulturae9040477 .
Fotirić Akšić, Milica, Tešić, Živoslav, Kalaba, Milica, Ćirić, Ivanka, Pezo, Lato, Lončar, Biljana, Gašić, Uroš, Dojčinović, Biljana, Tosti, Tomislav, Meland, Mekjell, "Breakthrough Analysis of Chemical Composition and Applied Chemometrics of European Plum Cultivars Grown in Norway" in Horticulturae, 9, no. 4 (2023),
https://doi.org/10.3390/horticulturae9040477 . .
2
1

Polyphenolic and Chemical Profiles of Honey From the Tara Mountain in Serbia

Nedić, Nebojša; Nešović, Milica; Radišić, Predrag; Gašić, Uroš; Baošić, Rada; Joksimović, Kristina; Pezo, Lato; Tešić, Živoslav; Vovk, Irena

(Frontiers Media S.A., 2022)

TY  - JOUR
AU  - Nedić, Nebojša
AU  - Nešović, Milica
AU  - Radišić, Predrag
AU  - Gašić, Uroš
AU  - Baošić, Rada
AU  - Joksimović, Kristina
AU  - Pezo, Lato
AU  - Tešić, Živoslav
AU  - Vovk, Irena
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5357
AB  - This study presents a detailed characterization of 27 honey samples from the Tara Mountain region in Serbia using different comprehensive techniques and methods. The types of the honey samples were defined as monofloral (4 samples), honeydew (5 samples) and polyfloral (18 samples) honey based on determined polyphenol content, antioxidant activity, electrical conductivity and melissopalynological analyses. Physicochemical parameters such as pH (4.13–4.94), diastase activity (24.20–41.70 DN), acidity (14.60–29.70 meq/kg), content of 5-(hydroxymethyl)furfural (in range below 5, up to 16.90 mg/kg), sucrose (0.20–3.90 g/100 g), and moisture content (15.01–19.23%) confirmed the required quality of the honey samples. Sensory analysis revealed honey characteristics favorable to consumers. Analyses of 19 phenolic compounds using ultra-high-performance liquid chromatography with a diode-array detection and triple quadrupole mass spectrometry (UHPLC-DAD-MS/MS) revealed six phenolic acids and 13 other compounds from the group of flavonoids and their glycosides. In all the samples the highest content was determined for p-coumaric acid, followed by caffeic acid and pinocembrin. Besides total phenolic content and radical scavenging activity, antimicrobial activity was also examined. Most honey samples showed bactericidal activity against Staphylococcus aureus and bacteriostatic activity against Escherichia coli, while none of the honey samples inhibited the growth of Candida albicans. Chemometric analyses were applied for an in-depth study of the results to further evaluate the characteristics of the honey samples studied. Principal component analysis (PCA) was used for assessing the differences in physicochemical parameters, polyphenols content and antioxidant capacity between honey samples. The unrooted cluster tree was used to group the samples based on the melissopalynological analyses.
PB  - Frontiers Media S.A.
T2  - Frontiers in Nutrition
T1  - Polyphenolic and Chemical Profiles of Honey From the Tara Mountain in Serbia
VL  - 9
DO  - 10.3389/fnut.2022.941463
ER  - 
@article{
author = "Nedić, Nebojša and Nešović, Milica and Radišić, Predrag and Gašić, Uroš and Baošić, Rada and Joksimović, Kristina and Pezo, Lato and Tešić, Živoslav and Vovk, Irena",
year = "2022",
abstract = "This study presents a detailed characterization of 27 honey samples from the Tara Mountain region in Serbia using different comprehensive techniques and methods. The types of the honey samples were defined as monofloral (4 samples), honeydew (5 samples) and polyfloral (18 samples) honey based on determined polyphenol content, antioxidant activity, electrical conductivity and melissopalynological analyses. Physicochemical parameters such as pH (4.13–4.94), diastase activity (24.20–41.70 DN), acidity (14.60–29.70 meq/kg), content of 5-(hydroxymethyl)furfural (in range below 5, up to 16.90 mg/kg), sucrose (0.20–3.90 g/100 g), and moisture content (15.01–19.23%) confirmed the required quality of the honey samples. Sensory analysis revealed honey characteristics favorable to consumers. Analyses of 19 phenolic compounds using ultra-high-performance liquid chromatography with a diode-array detection and triple quadrupole mass spectrometry (UHPLC-DAD-MS/MS) revealed six phenolic acids and 13 other compounds from the group of flavonoids and their glycosides. In all the samples the highest content was determined for p-coumaric acid, followed by caffeic acid and pinocembrin. Besides total phenolic content and radical scavenging activity, antimicrobial activity was also examined. Most honey samples showed bactericidal activity against Staphylococcus aureus and bacteriostatic activity against Escherichia coli, while none of the honey samples inhibited the growth of Candida albicans. Chemometric analyses were applied for an in-depth study of the results to further evaluate the characteristics of the honey samples studied. Principal component analysis (PCA) was used for assessing the differences in physicochemical parameters, polyphenols content and antioxidant capacity between honey samples. The unrooted cluster tree was used to group the samples based on the melissopalynological analyses.",
publisher = "Frontiers Media S.A.",
journal = "Frontiers in Nutrition",
title = "Polyphenolic and Chemical Profiles of Honey From the Tara Mountain in Serbia",
volume = "9",
doi = "10.3389/fnut.2022.941463"
}
Nedić, N., Nešović, M., Radišić, P., Gašić, U., Baošić, R., Joksimović, K., Pezo, L., Tešić, Ž.,& Vovk, I.. (2022). Polyphenolic and Chemical Profiles of Honey From the Tara Mountain in Serbia. in Frontiers in Nutrition
Frontiers Media S.A.., 9.
https://doi.org/10.3389/fnut.2022.941463
Nedić N, Nešović M, Radišić P, Gašić U, Baošić R, Joksimović K, Pezo L, Tešić Ž, Vovk I. Polyphenolic and Chemical Profiles of Honey From the Tara Mountain in Serbia. in Frontiers in Nutrition. 2022;9.
doi:10.3389/fnut.2022.941463 .
Nedić, Nebojša, Nešović, Milica, Radišić, Predrag, Gašić, Uroš, Baošić, Rada, Joksimović, Kristina, Pezo, Lato, Tešić, Živoslav, Vovk, Irena, "Polyphenolic and Chemical Profiles of Honey From the Tara Mountain in Serbia" in Frontiers in Nutrition, 9 (2022),
https://doi.org/10.3389/fnut.2022.941463 . .
1
18
10

Chemical Fruit Profiles of Different Raspberry Cultivars Grown in Specific Norwegian Agroclimatic Conditions

Fotirić Akšić, Milica; Nešović, Milica; Ćirić, Ivanka; Tešić, Živoslav; Pezo, Lato; Tosti, Tomislav; Gašić, Uroš; Dojčinović, Biljana; Lončar, Biljana; Meland, Mekjell

(MDPI AG, 2022)

TY  - JOUR
AU  - Fotirić Akšić, Milica
AU  - Nešović, Milica
AU  - Ćirić, Ivanka
AU  - Tešić, Živoslav
AU  - Pezo, Lato
AU  - Tosti, Tomislav
AU  - Gašić, Uroš
AU  - Dojčinović, Biljana
AU  - Lončar, Biljana
AU  - Meland, Mekjell
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5575
AB  - Raspberries are considered valuable fruits due to their high levels of nutrients and phytochemicals, which have many beneficial effects on humans. As many external factors affect the composition of these fruits (the type of cultivation, soil characteristics, ripeness, storage time and post-harvest technologies, cultivar/genotype, and climatic conditions), the goal of this study was to analyze different raspberry cultivars grown in Norway. Considering that Norway is a country with specific climatic conditions, as well as has a limited period of fruit vegetation, another important goal of this study was also to compare raspberries from different Norwegian areas, as well as different grown cultivars. Modern analytical techniques, such as high-performance anion-exchange liquid chromatography with pulsed amperometric detection (HPEAC-PAD), ultra-high-performance liquid chromatography with diode array detector coupled to triple quadrupole mass spectrometry (UHPLC-DAD MS/MS), and inductively coupled plasma–optical emission spectrometry (ICP-OES), provided a detailed examination of the raspberry extract samples. Based on their high levels of minerals (especially N, P, and K), organic acids (predominantly citric and malic acids), sugars (glucose, fructose, sucrose, and galactose), and polyphenols (ellagic acid, syringic acid, quercetin, and rutin), Norwegian raspberries could be considered fruits with increased health-beneficial compounds. The chemical composition of the studied cultivars depended on the locality of growth.
PB  - MDPI AG
T2  - Horticulturae
T1  - Chemical Fruit Profiles of Different Raspberry Cultivars Grown in Specific Norwegian Agroclimatic Conditions
VL  - 8
IS  - 9
SP  - 765
DO  - 10.3390/horticulturae8090765
ER  - 
@article{
author = "Fotirić Akšić, Milica and Nešović, Milica and Ćirić, Ivanka and Tešić, Živoslav and Pezo, Lato and Tosti, Tomislav and Gašić, Uroš and Dojčinović, Biljana and Lončar, Biljana and Meland, Mekjell",
year = "2022",
abstract = "Raspberries are considered valuable fruits due to their high levels of nutrients and phytochemicals, which have many beneficial effects on humans. As many external factors affect the composition of these fruits (the type of cultivation, soil characteristics, ripeness, storage time and post-harvest technologies, cultivar/genotype, and climatic conditions), the goal of this study was to analyze different raspberry cultivars grown in Norway. Considering that Norway is a country with specific climatic conditions, as well as has a limited period of fruit vegetation, another important goal of this study was also to compare raspberries from different Norwegian areas, as well as different grown cultivars. Modern analytical techniques, such as high-performance anion-exchange liquid chromatography with pulsed amperometric detection (HPEAC-PAD), ultra-high-performance liquid chromatography with diode array detector coupled to triple quadrupole mass spectrometry (UHPLC-DAD MS/MS), and inductively coupled plasma–optical emission spectrometry (ICP-OES), provided a detailed examination of the raspberry extract samples. Based on their high levels of minerals (especially N, P, and K), organic acids (predominantly citric and malic acids), sugars (glucose, fructose, sucrose, and galactose), and polyphenols (ellagic acid, syringic acid, quercetin, and rutin), Norwegian raspberries could be considered fruits with increased health-beneficial compounds. The chemical composition of the studied cultivars depended on the locality of growth.",
publisher = "MDPI AG",
journal = "Horticulturae",
title = "Chemical Fruit Profiles of Different Raspberry Cultivars Grown in Specific Norwegian Agroclimatic Conditions",
volume = "8",
number = "9",
pages = "765",
doi = "10.3390/horticulturae8090765"
}
Fotirić Akšić, M., Nešović, M., Ćirić, I., Tešić, Ž., Pezo, L., Tosti, T., Gašić, U., Dojčinović, B., Lončar, B.,& Meland, M.. (2022). Chemical Fruit Profiles of Different Raspberry Cultivars Grown in Specific Norwegian Agroclimatic Conditions. in Horticulturae
MDPI AG., 8(9), 765.
https://doi.org/10.3390/horticulturae8090765
Fotirić Akšić M, Nešović M, Ćirić I, Tešić Ž, Pezo L, Tosti T, Gašić U, Dojčinović B, Lončar B, Meland M. Chemical Fruit Profiles of Different Raspberry Cultivars Grown in Specific Norwegian Agroclimatic Conditions. in Horticulturae. 2022;8(9):765.
doi:10.3390/horticulturae8090765 .
Fotirić Akšić, Milica, Nešović, Milica, Ćirić, Ivanka, Tešić, Živoslav, Pezo, Lato, Tosti, Tomislav, Gašić, Uroš, Dojčinović, Biljana, Lončar, Biljana, Meland, Mekjell, "Chemical Fruit Profiles of Different Raspberry Cultivars Grown in Specific Norwegian Agroclimatic Conditions" in Horticulturae, 8, no. 9 (2022):765,
https://doi.org/10.3390/horticulturae8090765 . .
2
18
12

Polyphenolics and Chemical Profiles of Domestic Norwegian Apple (Malus × domestica Borkh.) Cultivars

Fotirić Akšić, Milica; Nešović, Milica; Ćirić, Ivanka; Tešić, Živoslav; Pezo, Lato; Tosti, Tomislav; Gašić, Uroš; Dojčinović, Biljana; Lončar, Biljana; Meland, Mekjell

(Frontiers Media SA, 2022)

TY  - JOUR
AU  - Fotirić Akšić, Milica
AU  - Nešović, Milica
AU  - Ćirić, Ivanka
AU  - Tešić, Živoslav
AU  - Pezo, Lato
AU  - Tosti, Tomislav
AU  - Gašić, Uroš
AU  - Dojčinović, Biljana
AU  - Lončar, Biljana
AU  - Meland, Mekjell
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5576
AB  - Using modern analytical techniques, a comprehensive study of the chemical composition of fruits from apple cultivars grown in Western Norway during 2019 and 2020 was done. Metals, sugars, organic acids, antioxidant tests, and polyphenol content have been observed. In all investigated samples, the most dominant sugars were glucose, fructose, and sucrose. Among 11 tested organic acids, the dominant was malic acid, followed by citric and maleic acid. The most common metal was potassium, followed by magnesium and zinc. The quantification of polyphenols showed that among the 11 quantified polyphenols, chlorogenic acid, quercetin 3-O-rhamnoside, quercetin 3-O-glucoside, quercetin, and phlorizin were the most abundant. A detailed study of the polyphenolic profile of nine investigated apple samples provided 30 identified polyphenolic compounds from the class of hydroxybenzoic and hydroxycinnamic acids, flavonoids, and dihydrochalcones. In addition to the identified 3-O-caffeoylquinic acid, its two isomers of 5-O-caffeoylquinic acid and three esters were also found. Present polyphenols of the tested apples provided significant data on the quality of Norwegian apples, and they contribute to the distinguishing of these apple samples.
PB  - Frontiers Media SA
T2  - Frontiers in Nutrition
T1  - Polyphenolics and Chemical Profiles of Domestic Norwegian Apple (Malus  × domestica Borkh.) Cultivars
VL  - 9
SP  - 941487
DO  - 10.3389/fnut.2022.941487
ER  - 
@article{
author = "Fotirić Akšić, Milica and Nešović, Milica and Ćirić, Ivanka and Tešić, Živoslav and Pezo, Lato and Tosti, Tomislav and Gašić, Uroš and Dojčinović, Biljana and Lončar, Biljana and Meland, Mekjell",
year = "2022",
abstract = "Using modern analytical techniques, a comprehensive study of the chemical composition of fruits from apple cultivars grown in Western Norway during 2019 and 2020 was done. Metals, sugars, organic acids, antioxidant tests, and polyphenol content have been observed. In all investigated samples, the most dominant sugars were glucose, fructose, and sucrose. Among 11 tested organic acids, the dominant was malic acid, followed by citric and maleic acid. The most common metal was potassium, followed by magnesium and zinc. The quantification of polyphenols showed that among the 11 quantified polyphenols, chlorogenic acid, quercetin 3-O-rhamnoside, quercetin 3-O-glucoside, quercetin, and phlorizin were the most abundant. A detailed study of the polyphenolic profile of nine investigated apple samples provided 30 identified polyphenolic compounds from the class of hydroxybenzoic and hydroxycinnamic acids, flavonoids, and dihydrochalcones. In addition to the identified 3-O-caffeoylquinic acid, its two isomers of 5-O-caffeoylquinic acid and three esters were also found. Present polyphenols of the tested apples provided significant data on the quality of Norwegian apples, and they contribute to the distinguishing of these apple samples.",
publisher = "Frontiers Media SA",
journal = "Frontiers in Nutrition",
title = "Polyphenolics and Chemical Profiles of Domestic Norwegian Apple (Malus  × domestica Borkh.) Cultivars",
volume = "9",
pages = "941487",
doi = "10.3389/fnut.2022.941487"
}
Fotirić Akšić, M., Nešović, M., Ćirić, I., Tešić, Ž., Pezo, L., Tosti, T., Gašić, U., Dojčinović, B., Lončar, B.,& Meland, M.. (2022). Polyphenolics and Chemical Profiles of Domestic Norwegian Apple (Malus  × domestica Borkh.) Cultivars. in Frontiers in Nutrition
Frontiers Media SA., 9, 941487.
https://doi.org/10.3389/fnut.2022.941487
Fotirić Akšić M, Nešović M, Ćirić I, Tešić Ž, Pezo L, Tosti T, Gašić U, Dojčinović B, Lončar B, Meland M. Polyphenolics and Chemical Profiles of Domestic Norwegian Apple (Malus  × domestica Borkh.) Cultivars. in Frontiers in Nutrition. 2022;9:941487.
doi:10.3389/fnut.2022.941487 .
Fotirić Akšić, Milica, Nešović, Milica, Ćirić, Ivanka, Tešić, Živoslav, Pezo, Lato, Tosti, Tomislav, Gašić, Uroš, Dojčinović, Biljana, Lončar, Biljana, Meland, Mekjell, "Polyphenolics and Chemical Profiles of Domestic Norwegian Apple (Malus  × domestica Borkh.) Cultivars" in Frontiers in Nutrition, 9 (2022):941487,
https://doi.org/10.3389/fnut.2022.941487 . .
13
9

Content and Nutritional Value of Selected Biogenic Elements in Monofloral Sunflower Bee-Collected Pollen from Serbia

Kostić, Aleksandar Ž.; Dojčinović, Biljana; Nedić, Nebojša; Milinčić, Danijel D.; Pantelić, Nebojša Ð.; Stanojević, Sladjana P.; Barać, Miroljub B.; Tešić, Živoslav; Pešić, Mirjana B.; Brka, Muhamed; Omanović-Mikličanin, Enisa; Karić, Lutvija; Falan, Vedad; Toroman, Almir

(Springer International Publishing, 2020)

TY  - CONF
AU  - Kostić, Aleksandar Ž.
AU  - Dojčinović, Biljana
AU  - Nedić, Nebojša
AU  - Milinčić, Danijel D.
AU  - Pantelić, Nebojša Ð.
AU  - Stanojević, Sladjana P.
AU  - Barać, Miroljub B.
AU  - Tešić, Živoslav
AU  - Pešić, Mirjana B.
AU  - Brka, Muhamed
AU  - Omanović-Mikličanin, Enisa
AU  - Karić, Lutvija
AU  - Falan, Vedad
AU  - Toroman, Almir
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4169
AB  - Pollen (floral or bee-collected) can be used as a good source of different nutrients including several important biogenic elements (minerals). The aim of this study was to determine content of selected biogenic elements (phosphorous, potassium, sulphur, calcium, magnesium, iron and zinc) in monofloral bee-collected pollen originated from sunflower (Helianthus annuus L.) plants grown in Serbia and to estimate its nutritional value regarding to elements content. In that purpose ICP-OES analytical method was applied. According to obtained results the examined pollen sample contains above mentioned elements in following quantities: P – 3523.98 mg/kg; K – 2869.13 mg/kg; S – 1951.74 mg/kg; Ca – 1919.20 mg/kg; Mg – 654.36 mg/kg; Fe –83.55 mg/kg; Zn – 45.92 mg/kg of dry weight. Based on recommended daily intakes for iron, phosphorus and zinc application of pollen, as food or food ingredient, will cover meaningful part of human needs for these three important elements.
PB  - Springer International Publishing
C3  - 30th Scientific-Experts Conference of Agriculture and Food Industry
T1  - Content and Nutritional Value of Selected Biogenic Elements in Monofloral Sunflower Bee-Collected Pollen from Serbia
SP  - 211
EP  - 217
DO  - 10.1007/978-3-030-40049-1_27
ER  - 
@conference{
author = "Kostić, Aleksandar Ž. and Dojčinović, Biljana and Nedić, Nebojša and Milinčić, Danijel D. and Pantelić, Nebojša Ð. and Stanojević, Sladjana P. and Barać, Miroljub B. and Tešić, Živoslav and Pešić, Mirjana B. and Brka, Muhamed and Omanović-Mikličanin, Enisa and Karić, Lutvija and Falan, Vedad and Toroman, Almir",
year = "2020",
abstract = "Pollen (floral or bee-collected) can be used as a good source of different nutrients including several important biogenic elements (minerals). The aim of this study was to determine content of selected biogenic elements (phosphorous, potassium, sulphur, calcium, magnesium, iron and zinc) in monofloral bee-collected pollen originated from sunflower (Helianthus annuus L.) plants grown in Serbia and to estimate its nutritional value regarding to elements content. In that purpose ICP-OES analytical method was applied. According to obtained results the examined pollen sample contains above mentioned elements in following quantities: P – 3523.98 mg/kg; K – 2869.13 mg/kg; S – 1951.74 mg/kg; Ca – 1919.20 mg/kg; Mg – 654.36 mg/kg; Fe –83.55 mg/kg; Zn – 45.92 mg/kg of dry weight. Based on recommended daily intakes for iron, phosphorus and zinc application of pollen, as food or food ingredient, will cover meaningful part of human needs for these three important elements.",
publisher = "Springer International Publishing",
journal = "30th Scientific-Experts Conference of Agriculture and Food Industry",
title = "Content and Nutritional Value of Selected Biogenic Elements in Monofloral Sunflower Bee-Collected Pollen from Serbia",
pages = "211-217",
doi = "10.1007/978-3-030-40049-1_27"
}
Kostić, A. Ž., Dojčinović, B., Nedić, N., Milinčić, D. D., Pantelić, N. Ð., Stanojević, S. P., Barać, M. B., Tešić, Ž., Pešić, M. B., Brka, M., Omanović-Mikličanin, E., Karić, L., Falan, V.,& Toroman, A.. (2020). Content and Nutritional Value of Selected Biogenic Elements in Monofloral Sunflower Bee-Collected Pollen from Serbia. in 30th Scientific-Experts Conference of Agriculture and Food Industry
Springer International Publishing., 211-217.
https://doi.org/10.1007/978-3-030-40049-1_27
Kostić AŽ, Dojčinović B, Nedić N, Milinčić DD, Pantelić NÐ, Stanojević SP, Barać MB, Tešić Ž, Pešić MB, Brka M, Omanović-Mikličanin E, Karić L, Falan V, Toroman A. Content and Nutritional Value of Selected Biogenic Elements in Monofloral Sunflower Bee-Collected Pollen from Serbia. in 30th Scientific-Experts Conference of Agriculture and Food Industry. 2020;:211-217.
doi:10.1007/978-3-030-40049-1_27 .
Kostić, Aleksandar Ž., Dojčinović, Biljana, Nedić, Nebojša, Milinčić, Danijel D., Pantelić, Nebojša Ð., Stanojević, Sladjana P., Barać, Miroljub B., Tešić, Živoslav, Pešić, Mirjana B., Brka, Muhamed, Omanović-Mikličanin, Enisa, Karić, Lutvija, Falan, Vedad, Toroman, Almir, "Content and Nutritional Value of Selected Biogenic Elements in Monofloral Sunflower Bee-Collected Pollen from Serbia" in 30th Scientific-Experts Conference of Agriculture and Food Industry (2020):211-217,
https://doi.org/10.1007/978-3-030-40049-1_27 . .
2
2

Influence of rootstocks on the chemical composition of the fruits of plum cultivars

Radović, Mirjana; Milatović, Dragan; Tešić, Živoslav; Tosti, Tomislav; Gašić, Uroš; Dojčinović, Biljana; Dabić Zagorac, Dragana

(Elsevier, 2020)

TY  - JOUR
AU  - Radović, Mirjana
AU  - Milatović, Dragan
AU  - Tešić, Živoslav
AU  - Tosti, Tomislav
AU  - Gašić, Uroš
AU  - Dojčinović, Biljana
AU  - Dabić Zagorac, Dragana
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3601
AB  - This paper presents the chemical composition of the fruits of three European plum cultivars (‘Cacanska Rana’,
‘Cacanska Lepotica’, and ‘Cacanska Najbolja’) grafted on four rootstocks (Myrobalan, ‘Pixy’, ‘Fereley’, and ‘St.
Julien A’). The rootstock/cultivar combinations significantly influenced the content of most of the phenolic
compounds in the plum skin and flesh. The total anthocyanin content in the skin ranged from 1.87 to 7.33 mg
cyanidin-3-glucoside g−1 fresh weight. The major phenolic compound in the skin was rutin, which ranged from
95 to 238 mg kg−1, while in the flesh, cinnamic acid and catechin were dominant. The total sugar content in the
fruit ranged from 66.2–147 mg g−1. The highest glucose and fructose contents were in ‘Cacanska Lepotica’, then
in ‘Cacanska Najbolja’, and the lowest were in ‘Cacanska Rana’ cultivar. The highest contents of glucose and
sucrose were found in fruits from trees grafted on Myrobalan rootstock, and the lowest in fruits from trees
grafted on ‘St. Julien A’ rootstock. The rootstocks significantly influenced the potassium, calcium, and copper
contents in the plum fruit. The results of this study demonstrate the significant effect of rootstocks on the
phenolic and sugar profiles, and on the mineral content of the plum fruits.
PB  - Elsevier
T2  - Journal of Food Composition and Analysis
T1  - Influence of rootstocks on the chemical composition of the fruits of plum cultivars
VL  - 92
SP  - 103480
DO  - 10.1016/j.jfca.2020.103480
ER  - 
@article{
author = "Radović, Mirjana and Milatović, Dragan and Tešić, Živoslav and Tosti, Tomislav and Gašić, Uroš and Dojčinović, Biljana and Dabić Zagorac, Dragana",
year = "2020",
abstract = "This paper presents the chemical composition of the fruits of three European plum cultivars (‘Cacanska Rana’,
‘Cacanska Lepotica’, and ‘Cacanska Najbolja’) grafted on four rootstocks (Myrobalan, ‘Pixy’, ‘Fereley’, and ‘St.
Julien A’). The rootstock/cultivar combinations significantly influenced the content of most of the phenolic
compounds in the plum skin and flesh. The total anthocyanin content in the skin ranged from 1.87 to 7.33 mg
cyanidin-3-glucoside g−1 fresh weight. The major phenolic compound in the skin was rutin, which ranged from
95 to 238 mg kg−1, while in the flesh, cinnamic acid and catechin were dominant. The total sugar content in the
fruit ranged from 66.2–147 mg g−1. The highest glucose and fructose contents were in ‘Cacanska Lepotica’, then
in ‘Cacanska Najbolja’, and the lowest were in ‘Cacanska Rana’ cultivar. The highest contents of glucose and
sucrose were found in fruits from trees grafted on Myrobalan rootstock, and the lowest in fruits from trees
grafted on ‘St. Julien A’ rootstock. The rootstocks significantly influenced the potassium, calcium, and copper
contents in the plum fruit. The results of this study demonstrate the significant effect of rootstocks on the
phenolic and sugar profiles, and on the mineral content of the plum fruits.",
publisher = "Elsevier",
journal = "Journal of Food Composition and Analysis",
title = "Influence of rootstocks on the chemical composition of the fruits of plum cultivars",
volume = "92",
pages = "103480",
doi = "10.1016/j.jfca.2020.103480"
}
Radović, M., Milatović, D., Tešić, Ž., Tosti, T., Gašić, U., Dojčinović, B.,& Dabić Zagorac, D.. (2020). Influence of rootstocks on the chemical composition of the fruits of plum cultivars. in Journal of Food Composition and Analysis
Elsevier., 92, 103480.
https://doi.org/10.1016/j.jfca.2020.103480
Radović M, Milatović D, Tešić Ž, Tosti T, Gašić U, Dojčinović B, Dabić Zagorac D. Influence of rootstocks on the chemical composition of the fruits of plum cultivars. in Journal of Food Composition and Analysis. 2020;92:103480.
doi:10.1016/j.jfca.2020.103480 .
Radović, Mirjana, Milatović, Dragan, Tešić, Živoslav, Tosti, Tomislav, Gašić, Uroš, Dojčinović, Biljana, Dabić Zagorac, Dragana, "Influence of rootstocks on the chemical composition of the fruits of plum cultivars" in Journal of Food Composition and Analysis, 92 (2020):103480,
https://doi.org/10.1016/j.jfca.2020.103480 . .
28
9
28

Thin-layer chromatography in quantitative structure-activity relationship studies

Milojković-Opsenica, Dušanka; Andrić, Filip; Šegan, Sandra; Trifković, Jelena; Tešić, Živoslav

(Taylor & Francis Inc, Philadelphia, 2018)

TY  - JOUR
AU  - Milojković-Opsenica, Dušanka
AU  - Andrić, Filip
AU  - Šegan, Sandra
AU  - Trifković, Jelena
AU  - Tešić, Živoslav
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2475
AB  - The methods of correlating molecular structure of substances expressed as descriptors, to their biological activity are commonly denoted as Quantitative Structure-Activity Relationships (QSARs). This concept, typically applied in drug discovery processes, is also widely used for correlation of molecular structure and physicochemical properties of solutes in so-called quantitative structure-property relationship (QSPR) studies, as well as for explanation of chromatographic behavior, i.e., separation mechanisms of analytes, where is termed as quantitative structure-retention relationship (QSRR). Mathematical expressions of structural characteristics of substances, named as molecular descriptors, can be calculated by various computational techniques or experimentally determined by different analytical methods. Thin-layer chromatography as a rapid, sensitive, and economical liquid chromatographic method has been widely used for determination of various chromatographic descriptors applicable in QSAR/QSPR studies. An overview of recently published papers dealing with this concept is presented. [GRAPHICS] .
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography & Related Technologies
T1  - Thin-layer chromatography in quantitative structure-activity relationship studies
VL  - 41
IS  - 6
SP  - 272
EP  - 281
DO  - 10.1080/10826076.2018.1447892
ER  - 
@article{
author = "Milojković-Opsenica, Dušanka and Andrić, Filip and Šegan, Sandra and Trifković, Jelena and Tešić, Živoslav",
year = "2018",
abstract = "The methods of correlating molecular structure of substances expressed as descriptors, to their biological activity are commonly denoted as Quantitative Structure-Activity Relationships (QSARs). This concept, typically applied in drug discovery processes, is also widely used for correlation of molecular structure and physicochemical properties of solutes in so-called quantitative structure-property relationship (QSPR) studies, as well as for explanation of chromatographic behavior, i.e., separation mechanisms of analytes, where is termed as quantitative structure-retention relationship (QSRR). Mathematical expressions of structural characteristics of substances, named as molecular descriptors, can be calculated by various computational techniques or experimentally determined by different analytical methods. Thin-layer chromatography as a rapid, sensitive, and economical liquid chromatographic method has been widely used for determination of various chromatographic descriptors applicable in QSAR/QSPR studies. An overview of recently published papers dealing with this concept is presented. [GRAPHICS] .",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography & Related Technologies",
title = "Thin-layer chromatography in quantitative structure-activity relationship studies",
volume = "41",
number = "6",
pages = "272-281",
doi = "10.1080/10826076.2018.1447892"
}
Milojković-Opsenica, D., Andrić, F., Šegan, S., Trifković, J.,& Tešić, Ž.. (2018). Thin-layer chromatography in quantitative structure-activity relationship studies. in Journal of Liquid Chromatography & Related Technologies
Taylor & Francis Inc, Philadelphia., 41(6), 272-281.
https://doi.org/10.1080/10826076.2018.1447892
Milojković-Opsenica D, Andrić F, Šegan S, Trifković J, Tešić Ž. Thin-layer chromatography in quantitative structure-activity relationship studies. in Journal of Liquid Chromatography & Related Technologies. 2018;41(6):272-281.
doi:10.1080/10826076.2018.1447892 .
Milojković-Opsenica, Dušanka, Andrić, Filip, Šegan, Sandra, Trifković, Jelena, Tešić, Živoslav, "Thin-layer chromatography in quantitative structure-activity relationship studies" in Journal of Liquid Chromatography & Related Technologies, 41, no. 6 (2018):272-281,
https://doi.org/10.1080/10826076.2018.1447892 . .
6
5
6

Chromatographic methods in determination of the soil-water partition coefficient

Andrić, Filip; Šegan, Sandra; Tešić, Živoslav; Milojković-Opsenica, Dušanka

(Taylor & Francis Inc, Philadelphia, 2016)

TY  - JOUR
AU  - Andrić, Filip
AU  - Šegan, Sandra
AU  - Tešić, Živoslav
AU  - Milojković-Opsenica, Dušanka
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1861
AB  - The soil-water partition coefficient normalized to the soil organic carbon content (K-OC) is one of essential properties governing the fate of organic chemicals in the soil-water compartment. It is a parameter of utmost importance when it comes to the removal of toxic organics in the waste water management facilities or placing a new chemical on the market. Since direct determination of K-OC based on tests involving soil-sorption measurements are expensive, time-consuming, tedious, and subject to different experimental difficulties and artifacts, different alternative methods have been developed for rapid indirect experimental determination and estimation of K-OC values. In the scope of the present work, we provide critical and historical overview of development and application of the main chromatographic methods, both high-performance liquid chromatography and thin-layer chromatographic techniques for indirect experimental determination of the soil-water partition coefficient as well as mobility assessment of environmentally important compounds in the soil. Chromatographic methods proved to be promising in this field, which is clearly demonstrated by their implementation in official guidelines for testing the chemicals.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography & Related Technologies
T1  - Chromatographic methods in determination of the soil-water partition coefficient
VL  - 39
IS  - 5-6
SP  - 249
EP  - 256
DO  - 10.1080/10826076.2016.1163173
ER  - 
@article{
author = "Andrić, Filip and Šegan, Sandra and Tešić, Živoslav and Milojković-Opsenica, Dušanka",
year = "2016",
abstract = "The soil-water partition coefficient normalized to the soil organic carbon content (K-OC) is one of essential properties governing the fate of organic chemicals in the soil-water compartment. It is a parameter of utmost importance when it comes to the removal of toxic organics in the waste water management facilities or placing a new chemical on the market. Since direct determination of K-OC based on tests involving soil-sorption measurements are expensive, time-consuming, tedious, and subject to different experimental difficulties and artifacts, different alternative methods have been developed for rapid indirect experimental determination and estimation of K-OC values. In the scope of the present work, we provide critical and historical overview of development and application of the main chromatographic methods, both high-performance liquid chromatography and thin-layer chromatographic techniques for indirect experimental determination of the soil-water partition coefficient as well as mobility assessment of environmentally important compounds in the soil. Chromatographic methods proved to be promising in this field, which is clearly demonstrated by their implementation in official guidelines for testing the chemicals.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography & Related Technologies",
title = "Chromatographic methods in determination of the soil-water partition coefficient",
volume = "39",
number = "5-6",
pages = "249-256",
doi = "10.1080/10826076.2016.1163173"
}
Andrić, F., Šegan, S., Tešić, Ž.,& Milojković-Opsenica, D.. (2016). Chromatographic methods in determination of the soil-water partition coefficient. in Journal of Liquid Chromatography & Related Technologies
Taylor & Francis Inc, Philadelphia., 39(5-6), 249-256.
https://doi.org/10.1080/10826076.2016.1163173
Andrić F, Šegan S, Tešić Ž, Milojković-Opsenica D. Chromatographic methods in determination of the soil-water partition coefficient. in Journal of Liquid Chromatography & Related Technologies. 2016;39(5-6):249-256.
doi:10.1080/10826076.2016.1163173 .
Andrić, Filip, Šegan, Sandra, Tešić, Živoslav, Milojković-Opsenica, Dušanka, "Chromatographic methods in determination of the soil-water partition coefficient" in Journal of Liquid Chromatography & Related Technologies, 39, no. 5-6 (2016):249-256,
https://doi.org/10.1080/10826076.2016.1163173 . .
5
3
5

Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography

Tosti, Tomislav; Šegan, Sandra; Milić, Dragana; Radoičić, Aleksandra D.; Tešić, Živoslav; Milojković-Opsenica, Dušanka

(Taylor & Francis Inc, Philadelphia, 2015)

TY  - JOUR
AU  - Tosti, Tomislav
AU  - Šegan, Sandra
AU  - Milić, Dragana
AU  - Radoičić, Aleksandra D.
AU  - Tešić, Živoslav
AU  - Milojković-Opsenica, Dušanka
PY  - 2015
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1646
AB  - Unmodified silica gel in combination with two mobile phases, acetone-n-hexane and acetonitrile-dichloromethane, was used in order to evaluate the capability of normal-phase (NP) chromatography on bare silica gel in estimation of lipophilicity of some polyoxygenated steroids. Soczewinski equation coefficients were employed as a measure of lipophilicity. The R-M(0) values obtained in NP-systems were correlated with those derived by extrapolation from reversed-phase (RP) systems. In addition, retention data, i.e., lipophilicity parameters determined in NP systems were compared with logP values calculated by use of several commercial computer programs. The results showed that chromatographic parameters R-M(0), and m obtained in NP system consisted of silica gel as stationary phase and acetone-n-hexane as mobile phase, are acceptable as the measures of lipophilicity of polyoxygenated steroids. The mechanism of retention was discussed.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography & Related Technologies
T1  - Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography
VL  - 38
IS  - 11
SP  - 1097
EP  - 1103
DO  - 10.1080/10826076.2015.1028287
ER  - 
@article{
author = "Tosti, Tomislav and Šegan, Sandra and Milić, Dragana and Radoičić, Aleksandra D. and Tešić, Živoslav and Milojković-Opsenica, Dušanka",
year = "2015",
abstract = "Unmodified silica gel in combination with two mobile phases, acetone-n-hexane and acetonitrile-dichloromethane, was used in order to evaluate the capability of normal-phase (NP) chromatography on bare silica gel in estimation of lipophilicity of some polyoxygenated steroids. Soczewinski equation coefficients were employed as a measure of lipophilicity. The R-M(0) values obtained in NP-systems were correlated with those derived by extrapolation from reversed-phase (RP) systems. In addition, retention data, i.e., lipophilicity parameters determined in NP systems were compared with logP values calculated by use of several commercial computer programs. The results showed that chromatographic parameters R-M(0), and m obtained in NP system consisted of silica gel as stationary phase and acetone-n-hexane as mobile phase, are acceptable as the measures of lipophilicity of polyoxygenated steroids. The mechanism of retention was discussed.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography & Related Technologies",
title = "Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography",
volume = "38",
number = "11",
pages = "1097-1103",
doi = "10.1080/10826076.2015.1028287"
}
Tosti, T., Šegan, S., Milić, D., Radoičić, A. D., Tešić, Ž.,& Milojković-Opsenica, D.. (2015). Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography. in Journal of Liquid Chromatography & Related Technologies
Taylor & Francis Inc, Philadelphia., 38(11), 1097-1103.
https://doi.org/10.1080/10826076.2015.1028287
Tosti T, Šegan S, Milić D, Radoičić AD, Tešić Ž, Milojković-Opsenica D. Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography. in Journal of Liquid Chromatography & Related Technologies. 2015;38(11):1097-1103.
doi:10.1080/10826076.2015.1028287 .
Tosti, Tomislav, Šegan, Sandra, Milić, Dragana, Radoičić, Aleksandra D., Tešić, Živoslav, Milojković-Opsenica, Dušanka, "Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography" in Journal of Liquid Chromatography & Related Technologies, 38, no. 11 (2015):1097-1103,
https://doi.org/10.1080/10826076.2015.1028287 . .
7
8
8

Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography

Tosti, Tomislav; Šegan, Sandra; Milić, Dragana; Radoičić, Aleksandra D.; Tešić, Živoslav; Milojković-Opsenica, Dušanka

(Taylor & Francis Inc, Philadelphia, 2015)

TY  - JOUR
AU  - Tosti, Tomislav
AU  - Šegan, Sandra
AU  - Milić, Dragana
AU  - Radoičić, Aleksandra D.
AU  - Tešić, Živoslav
AU  - Milojković-Opsenica, Dušanka
PY  - 2015
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3126
AB  - Unmodified silica gel in combination with two mobile phases, acetone-n-hexane and acetonitrile-dichloromethane, was used in order to evaluate the capability of normal-phase (NP) chromatography on bare silica gel in estimation of lipophilicity of some polyoxygenated steroids. Soczewinski equation coefficients were employed as a measure of lipophilicity. The R-M(0) values obtained in NP-systems were correlated with those derived by extrapolation from reversed-phase (RP) systems. In addition, retention data, i.e., lipophilicity parameters determined in NP systems were compared with logP values calculated by use of several commercial computer programs. The results showed that chromatographic parameters R-M(0), and m obtained in NP system consisted of silica gel as stationary phase and acetone-n-hexane as mobile phase, are acceptable as the measures of lipophilicity of polyoxygenated steroids. The mechanism of retention was discussed.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography & Related Technologies
T1  - Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography
VL  - 38
IS  - 11
SP  - 1097
EP  - 1103
DO  - 10.1080/10826076.2015.1028287
ER  - 
@article{
author = "Tosti, Tomislav and Šegan, Sandra and Milić, Dragana and Radoičić, Aleksandra D. and Tešić, Živoslav and Milojković-Opsenica, Dušanka",
year = "2015",
abstract = "Unmodified silica gel in combination with two mobile phases, acetone-n-hexane and acetonitrile-dichloromethane, was used in order to evaluate the capability of normal-phase (NP) chromatography on bare silica gel in estimation of lipophilicity of some polyoxygenated steroids. Soczewinski equation coefficients were employed as a measure of lipophilicity. The R-M(0) values obtained in NP-systems were correlated with those derived by extrapolation from reversed-phase (RP) systems. In addition, retention data, i.e., lipophilicity parameters determined in NP systems were compared with logP values calculated by use of several commercial computer programs. The results showed that chromatographic parameters R-M(0), and m obtained in NP system consisted of silica gel as stationary phase and acetone-n-hexane as mobile phase, are acceptable as the measures of lipophilicity of polyoxygenated steroids. The mechanism of retention was discussed.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography & Related Technologies",
title = "Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography",
volume = "38",
number = "11",
pages = "1097-1103",
doi = "10.1080/10826076.2015.1028287"
}
Tosti, T., Šegan, S., Milić, D., Radoičić, A. D., Tešić, Ž.,& Milojković-Opsenica, D.. (2015). Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography. in Journal of Liquid Chromatography & Related Technologies
Taylor & Francis Inc, Philadelphia., 38(11), 1097-1103.
https://doi.org/10.1080/10826076.2015.1028287
Tosti T, Šegan S, Milić D, Radoičić AD, Tešić Ž, Milojković-Opsenica D. Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography. in Journal of Liquid Chromatography & Related Technologies. 2015;38(11):1097-1103.
doi:10.1080/10826076.2015.1028287 .
Tosti, Tomislav, Šegan, Sandra, Milić, Dragana, Radoičić, Aleksandra D., Tešić, Živoslav, Milojković-Opsenica, Dušanka, "Estimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatography" in Journal of Liquid Chromatography & Related Technologies, 38, no. 11 (2015):1097-1103,
https://doi.org/10.1080/10826076.2015.1028287 . .
7
8
8

Lipophilicity Assessment of Ruthenium(II)-Arene Complexes by the Means of Reversed-Phase Thin-Layer Chromatography and DFT Calculations

Shweshein, Khalil Salem A. M.; Andrić, Filip; Radoičić, Aleksandra D.; Zlatar, Matija; Gruden-Pavlović, Maja; Tešić, Živoslav; Milojković-Opsenica, Dušanka

(Hindawi Publishing Corporation, New York, 2014)

TY  - JOUR
AU  - Shweshein, Khalil Salem A. M.
AU  - Andrić, Filip
AU  - Radoičić, Aleksandra D.
AU  - Zlatar, Matija
AU  - Gruden-Pavlović, Maja
AU  - Tešić, Živoslav
AU  - Milojković-Opsenica, Dušanka
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1538
AB  - The lipophilicity of ten ruthenium(II)-arene complexes was assessed by reversed-phase thin-layer chromatography (RP-TLC) on octadecyl silica stationary phase. The binary solvent systems composed of water and acetonitrile were used as mobile phase in order to determine chromatographic descriptors for lipophilicity estimation. Octanol-water partition coefficient, logK(OW), of tested complexes was experimentally determined using twenty-eight standard solutes which were analyzed under the same chromatographic conditions as target substances. In addition, ab initio density functional theory (DFT) computational approach was employed to calculate logK(OW) values from the differences in Gibbs' free solvation energies of the solute transfer from n-octanol to water. A good overall agreement between DFT calculated and experimentally determined logK(OW) values was established (R-2 = 0.8024-0.9658).
PB  - Hindawi Publishing Corporation, New York
T2  - Scientific World Journal
T1  - Lipophilicity Assessment of Ruthenium(II)-Arene Complexes by the Means of Reversed-Phase Thin-Layer Chromatography and DFT Calculations
DO  - 10.1155/2014/862796
ER  - 
@article{
author = "Shweshein, Khalil Salem A. M. and Andrić, Filip and Radoičić, Aleksandra D. and Zlatar, Matija and Gruden-Pavlović, Maja and Tešić, Živoslav and Milojković-Opsenica, Dušanka",
year = "2014",
abstract = "The lipophilicity of ten ruthenium(II)-arene complexes was assessed by reversed-phase thin-layer chromatography (RP-TLC) on octadecyl silica stationary phase. The binary solvent systems composed of water and acetonitrile were used as mobile phase in order to determine chromatographic descriptors for lipophilicity estimation. Octanol-water partition coefficient, logK(OW), of tested complexes was experimentally determined using twenty-eight standard solutes which were analyzed under the same chromatographic conditions as target substances. In addition, ab initio density functional theory (DFT) computational approach was employed to calculate logK(OW) values from the differences in Gibbs' free solvation energies of the solute transfer from n-octanol to water. A good overall agreement between DFT calculated and experimentally determined logK(OW) values was established (R-2 = 0.8024-0.9658).",
publisher = "Hindawi Publishing Corporation, New York",
journal = "Scientific World Journal",
title = "Lipophilicity Assessment of Ruthenium(II)-Arene Complexes by the Means of Reversed-Phase Thin-Layer Chromatography and DFT Calculations",
doi = "10.1155/2014/862796"
}
Shweshein, K. S. A. M., Andrić, F., Radoičić, A. D., Zlatar, M., Gruden-Pavlović, M., Tešić, Ž.,& Milojković-Opsenica, D.. (2014). Lipophilicity Assessment of Ruthenium(II)-Arene Complexes by the Means of Reversed-Phase Thin-Layer Chromatography and DFT Calculations. in Scientific World Journal
Hindawi Publishing Corporation, New York..
https://doi.org/10.1155/2014/862796
Shweshein KSAM, Andrić F, Radoičić AD, Zlatar M, Gruden-Pavlović M, Tešić Ž, Milojković-Opsenica D. Lipophilicity Assessment of Ruthenium(II)-Arene Complexes by the Means of Reversed-Phase Thin-Layer Chromatography and DFT Calculations. in Scientific World Journal. 2014;.
doi:10.1155/2014/862796 .
Shweshein, Khalil Salem A. M., Andrić, Filip, Radoičić, Aleksandra D., Zlatar, Matija, Gruden-Pavlović, Maja, Tešić, Živoslav, Milojković-Opsenica, Dušanka, "Lipophilicity Assessment of Ruthenium(II)-Arene Complexes by the Means of Reversed-Phase Thin-Layer Chromatography and DFT Calculations" in Scientific World Journal (2014),
https://doi.org/10.1155/2014/862796 . .
8
6
8

Assessment of lipophilicity of some biologically active arylpiperazines by rptlc and multivariate analysis

Stanojevic, Marija; Trifković, Jelena; Kostić Rajačić, Slađana; Šoškić, Vukić; Tešić, Živoslav; Milojković-Opsenica, Dušanka

(Taylor & Francis Inc, Philadelphia, 2014)

TY  - JOUR
AU  - Stanojevic, Marija
AU  - Trifković, Jelena
AU  - Kostić Rajačić, Slađana
AU  - Šoškić, Vukić
AU  - Tešić, Živoslav
AU  - Milojković-Opsenica, Dušanka
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1551
AB  - The chromatographic behavior of arylureas and arylacetamides derivatives with observed biological activity toward dopamine D-2 and 5-hydroxytryptamine 5HT(1A) receptors were examined by high-performance thin-layer chromatography in order to determine their lipophilicity and to correlate their structure and retention. The binary water-dimethyl sulfoxid mobile phases and RP-18 silica as stationary phase were used in order to determine chromatographic descriptors R-M(0), b, and C-0, as a measure of the lipophilicity of tested compounds. Based on the respective retention, the lipophilicity of the investigated compounds was discussed. Principal component analysis followed by partial least squares was used to select variables that best describe the behavior of the investigated compounds in the chromatographic system and to quantify their influences. The models reveal the importance of nonpolar properties of the solutes and their ability for hydrophobic interactions, as well as the importance of proton donating abilities and the size and the shape of the molecule, pointing out on that way the possible separation mechanism in the studied chromatographic systems.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography & Related Technologies
T1  - Assessment of lipophilicity of some biologically active arylpiperazines by rptlc and multivariate analysis
VL  - 37
IS  - 20
SP  - 2814
EP  - 2828
DO  - 10.1080/10826076.2014.907112
ER  - 
@article{
author = "Stanojevic, Marija and Trifković, Jelena and Kostić Rajačić, Slađana and Šoškić, Vukić and Tešić, Živoslav and Milojković-Opsenica, Dušanka",
year = "2014",
abstract = "The chromatographic behavior of arylureas and arylacetamides derivatives with observed biological activity toward dopamine D-2 and 5-hydroxytryptamine 5HT(1A) receptors were examined by high-performance thin-layer chromatography in order to determine their lipophilicity and to correlate their structure and retention. The binary water-dimethyl sulfoxid mobile phases and RP-18 silica as stationary phase were used in order to determine chromatographic descriptors R-M(0), b, and C-0, as a measure of the lipophilicity of tested compounds. Based on the respective retention, the lipophilicity of the investigated compounds was discussed. Principal component analysis followed by partial least squares was used to select variables that best describe the behavior of the investigated compounds in the chromatographic system and to quantify their influences. The models reveal the importance of nonpolar properties of the solutes and their ability for hydrophobic interactions, as well as the importance of proton donating abilities and the size and the shape of the molecule, pointing out on that way the possible separation mechanism in the studied chromatographic systems.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography & Related Technologies",
title = "Assessment of lipophilicity of some biologically active arylpiperazines by rptlc and multivariate analysis",
volume = "37",
number = "20",
pages = "2814-2828",
doi = "10.1080/10826076.2014.907112"
}
Stanojevic, M., Trifković, J., Kostić Rajačić, S., Šoškić, V., Tešić, Ž.,& Milojković-Opsenica, D.. (2014). Assessment of lipophilicity of some biologically active arylpiperazines by rptlc and multivariate analysis. in Journal of Liquid Chromatography & Related Technologies
Taylor & Francis Inc, Philadelphia., 37(20), 2814-2828.
https://doi.org/10.1080/10826076.2014.907112
Stanojevic M, Trifković J, Kostić Rajačić S, Šoškić V, Tešić Ž, Milojković-Opsenica D. Assessment of lipophilicity of some biologically active arylpiperazines by rptlc and multivariate analysis. in Journal of Liquid Chromatography & Related Technologies. 2014;37(20):2814-2828.
doi:10.1080/10826076.2014.907112 .
Stanojevic, Marija, Trifković, Jelena, Kostić Rajačić, Slađana, Šoškić, Vukić, Tešić, Živoslav, Milojković-Opsenica, Dušanka, "Assessment of lipophilicity of some biologically active arylpiperazines by rptlc and multivariate analysis" in Journal of Liquid Chromatography & Related Technologies, 37, no. 20 (2014):2814-2828,
https://doi.org/10.1080/10826076.2014.907112 . .
5
5
5

Chemical Characterization of Fruit Wine Made from Oblacinska Sour Cherry

Pantelić, Milica; Dabić, Dragana; Matijasevic, Sasa; Davidovic, Sonja; Dojčinović, Biljana; Milojković-Opsenica, Dušanka; Tešić, Živoslav; Natić, Maja

(Hindawi Publishing Corporation, New York, 2014)

TY  - JOUR
AU  - Pantelić, Milica
AU  - Dabić, Dragana
AU  - Matijasevic, Sasa
AU  - Davidovic, Sonja
AU  - Dojčinović, Biljana
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav
AU  - Natić, Maja
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1402
AB  - This paper was aimed at characterizing the wine obtained from Oblacinska, a native sour cherry cultivar. To the best of our knowledge, this is the first paper with the most comprehensive information on chemical characterization of Oblacinska sour cherry wine. The chemical composition was characterized by hyphenated chromatographic methods and traditional analytical techniques. A total of 24 compounds were quantified using the available standards and another 22 phenolic compounds were identified based on the accurate mass spectrographic search. Values of total phenolics content, total anthocyanin content, and radical scavenging activity for cherry wine sample were 1.938 mg gallic acid eqv L-1, 0.113 mg cyanidin-3-glucoside L-1, and 34.56%, respectively. In general, cherry wine polyphenolics in terms of nonanthocyanins and anthocyanins were shown to be distinctive when compared to grape wines. Naringenin and apigenin were characteristic only for cherry wine, and seven anthocyanins were distinctive for cherry wine.
PB  - Hindawi Publishing Corporation, New York
T2  - Scientific World Journal
T1  - Chemical Characterization of Fruit Wine Made from Oblacinska Sour Cherry
DO  - 10.1155/2014/454797
ER  - 
@article{
author = "Pantelić, Milica and Dabić, Dragana and Matijasevic, Sasa and Davidovic, Sonja and Dojčinović, Biljana and Milojković-Opsenica, Dušanka and Tešić, Živoslav and Natić, Maja",
year = "2014",
abstract = "This paper was aimed at characterizing the wine obtained from Oblacinska, a native sour cherry cultivar. To the best of our knowledge, this is the first paper with the most comprehensive information on chemical characterization of Oblacinska sour cherry wine. The chemical composition was characterized by hyphenated chromatographic methods and traditional analytical techniques. A total of 24 compounds were quantified using the available standards and another 22 phenolic compounds were identified based on the accurate mass spectrographic search. Values of total phenolics content, total anthocyanin content, and radical scavenging activity for cherry wine sample were 1.938 mg gallic acid eqv L-1, 0.113 mg cyanidin-3-glucoside L-1, and 34.56%, respectively. In general, cherry wine polyphenolics in terms of nonanthocyanins and anthocyanins were shown to be distinctive when compared to grape wines. Naringenin and apigenin were characteristic only for cherry wine, and seven anthocyanins were distinctive for cherry wine.",
publisher = "Hindawi Publishing Corporation, New York",
journal = "Scientific World Journal",
title = "Chemical Characterization of Fruit Wine Made from Oblacinska Sour Cherry",
doi = "10.1155/2014/454797"
}
Pantelić, M., Dabić, D., Matijasevic, S., Davidovic, S., Dojčinović, B., Milojković-Opsenica, D., Tešić, Ž.,& Natić, M.. (2014). Chemical Characterization of Fruit Wine Made from Oblacinska Sour Cherry. in Scientific World Journal
Hindawi Publishing Corporation, New York..
https://doi.org/10.1155/2014/454797
Pantelić M, Dabić D, Matijasevic S, Davidovic S, Dojčinović B, Milojković-Opsenica D, Tešić Ž, Natić M. Chemical Characterization of Fruit Wine Made from Oblacinska Sour Cherry. in Scientific World Journal. 2014;.
doi:10.1155/2014/454797 .
Pantelić, Milica, Dabić, Dragana, Matijasevic, Sasa, Davidovic, Sonja, Dojčinović, Biljana, Milojković-Opsenica, Dušanka, Tešić, Živoslav, Natić, Maja, "Chemical Characterization of Fruit Wine Made from Oblacinska Sour Cherry" in Scientific World Journal (2014),
https://doi.org/10.1155/2014/454797 . .
20
18
24

Chemical Composition of Two Different Extracts of Berries Harvested in Serbia

Pavlovic, Aleksandra V.; Dabić, Dragana; Momirovic, Nebojsa M.; Dojčinović, Biljana; Milojković-Opsenica, Dušanka; Tešić, Živoslav; Natić, Maja

(American Chemical Society (ACS), 2013)

TY  - JOUR
AU  - Pavlovic, Aleksandra V.
AU  - Dabić, Dragana
AU  - Momirovic, Nebojsa M.
AU  - Dojčinović, Biljana
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav
AU  - Natić, Maja
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1348
AB  - Total phenolic content (TPC), total anthocyanin content (TAC), free and total ellagic acid content, sugars, minerals, and radical scavenging activity were determined in nine berries harvested in Serbia. More than 30 phenolic compounds. were identified; among them, 11 polyphenols and cis,trans-abscisic acid were quantified using UHPLC coupled with an LTQ: Orbitrap XL mass analyzer. For the first time chrysin, naringenin, pinocembrin, and galangin were quantified in some of the investigated berry species. The extraction efficiency of the two extraction systems, methanol and acetone, was investigated. It was found that acetone is a better extracting solvent for TPC, whereas more TAC was extracted by methanol. TPC in acetone extracts ranged from 177.51 to 459.71 mg gallic acid equiv/100 g frozen weight. TAC ranged from 5.39 to 96.94 mg cyanidin-3-glucoside/100 g frozen weight in methanol extracts. The amounts of both free and total ellagic acid were found to be higher in the acetone extract in comparison to the methanol extract.
PB  - American Chemical Society (ACS)
T2  - Journal of Agricultural and Food Chemistry
T1  - Chemical Composition of Two Different Extracts of Berries Harvested in Serbia
VL  - 61
IS  - 17
SP  - 4188
EP  - 4194
DO  - 10.1021/jf400607f
ER  - 
@article{
author = "Pavlovic, Aleksandra V. and Dabić, Dragana and Momirovic, Nebojsa M. and Dojčinović, Biljana and Milojković-Opsenica, Dušanka and Tešić, Živoslav and Natić, Maja",
year = "2013",
abstract = "Total phenolic content (TPC), total anthocyanin content (TAC), free and total ellagic acid content, sugars, minerals, and radical scavenging activity were determined in nine berries harvested in Serbia. More than 30 phenolic compounds. were identified; among them, 11 polyphenols and cis,trans-abscisic acid were quantified using UHPLC coupled with an LTQ: Orbitrap XL mass analyzer. For the first time chrysin, naringenin, pinocembrin, and galangin were quantified in some of the investigated berry species. The extraction efficiency of the two extraction systems, methanol and acetone, was investigated. It was found that acetone is a better extracting solvent for TPC, whereas more TAC was extracted by methanol. TPC in acetone extracts ranged from 177.51 to 459.71 mg gallic acid equiv/100 g frozen weight. TAC ranged from 5.39 to 96.94 mg cyanidin-3-glucoside/100 g frozen weight in methanol extracts. The amounts of both free and total ellagic acid were found to be higher in the acetone extract in comparison to the methanol extract.",
publisher = "American Chemical Society (ACS)",
journal = "Journal of Agricultural and Food Chemistry",
title = "Chemical Composition of Two Different Extracts of Berries Harvested in Serbia",
volume = "61",
number = "17",
pages = "4188-4194",
doi = "10.1021/jf400607f"
}
Pavlovic, A. V., Dabić, D., Momirovic, N. M., Dojčinović, B., Milojković-Opsenica, D., Tešić, Ž.,& Natić, M.. (2013). Chemical Composition of Two Different Extracts of Berries Harvested in Serbia. in Journal of Agricultural and Food Chemistry
American Chemical Society (ACS)., 61(17), 4188-4194.
https://doi.org/10.1021/jf400607f
Pavlovic AV, Dabić D, Momirovic NM, Dojčinović B, Milojković-Opsenica D, Tešić Ž, Natić M. Chemical Composition of Two Different Extracts of Berries Harvested in Serbia. in Journal of Agricultural and Food Chemistry. 2013;61(17):4188-4194.
doi:10.1021/jf400607f .
Pavlovic, Aleksandra V., Dabić, Dragana, Momirovic, Nebojsa M., Dojčinović, Biljana, Milojković-Opsenica, Dušanka, Tešić, Živoslav, Natić, Maja, "Chemical Composition of Two Different Extracts of Berries Harvested in Serbia" in Journal of Agricultural and Food Chemistry, 61, no. 17 (2013):4188-4194,
https://doi.org/10.1021/jf400607f . .
52
34
57

Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters

Rabtti, El Hadi M. A.; Natić, Maja; Milojković-Opsenica, Dušanka; Trifković, Jelena; Tosti, Tomislav; Vučković, Ivan; Vajs, Vlatka; Tešić, Živoslav

(Serbian Chemical Soc, Belgrade, 2012)

TY  - JOUR
AU  - Rabtti, El Hadi M. A.
AU  - Natić, Maja
AU  - Milojković-Opsenica, Dušanka
AU  - Trifković, Jelena
AU  - Tosti, Tomislav
AU  - Vučković, Ivan
AU  - Vajs, Vlatka
AU  - Tešić, Živoslav
PY  - 2012
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/1554
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2721
AB  - Four lipophilicity descriptors (R-M(0), b, C-0 and PCl) for twelve coumarin derivatives were determined by reversed-phase thin-layer chromatography in order to analyze the descriptor which best describes the lipophilicity of the investigated coumarins. Moreover, possible chemical toxicity of coumarins, expressed as the probability of a compound to cause organ-specific health effects, was calculated using ACD/Tox Suite program. The quantitative relationships between toxicity and molecular descriptors, including experimentally determined lipophilicity descriptors obtained in current study were investigated using partial least square regression. The best models were obtained for kidney and liver health effects. Quantitative structure-toxicity relationship models revealed the importance of electric polarization descriptors, size descriptors and lipophilicity descriptors. The obtained models were used for the selection of the structural features of the compounds that are significantly affecting their absorption, distribution, metabolism, excretion and toxicity.
AB  - Primenom reverzno-fazne tankoslojne hromatografije na dvanaest derivata kumarina određena su četiri parametara lipofilnosti (RM0, b, C0 i PC1). Korelacijom dobijenih rezultata sa izračunatim log P vrednostima utvrđen je deskriptor koji na najbolji način opisuje lipofilnost ispitivanih kumarina. Pored toga izračunata je moguća hemijska toksičnost kumarina, izražena kao verovatnoća uticaja pomenutih jedinjenja na specifične organe (krv, kardiovaskularni sistem, gastrointestinalni sistem, bubrege, jetru i pluća) a koja je izračunata primenom ACD/Tox Suite programa. Dobijene vrednosti toksičnosti korelisane su sa molekulskim deskriptorima i eksperimentalno određenim parametrima lipofilnosti, primenom metode parcijalne regresije najmanjih kvadrata (partial least square regression). Uzimajući u obzir parametre koji opisuju kvalitet modela zavisnosti strukture i toksičnosti, utvrđeno je da su najbolji modeli dobijeni za uticaj kumarina na bubrege i jetru. Svi dobijeni modeli ukazuju na značaj električno polarizacionih deskriptora, kao i deskriptora koji opisuju veličinu i lipofilnost jedinjenja, a upotrebljeni su za utvrđivanje strukturnih karakteristika koje značajno utiču na njihovu apsorpciju, distribuciju, metabolizam, izlučivanje i toksičnost.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters
T1  - Analiza zavisnosti strukture i toksičnosti nekih prirodnih i sintetičkih kumarina korišćenjem retencionih parametara
VL  - 77
IS  - 10
SP  - 1443
EP  - 1456
DO  - 10.2298/JSC120716091R
ER  - 
@article{
author = "Rabtti, El Hadi M. A. and Natić, Maja and Milojković-Opsenica, Dušanka and Trifković, Jelena and Tosti, Tomislav and Vučković, Ivan and Vajs, Vlatka and Tešić, Živoslav",
year = "2012",
abstract = "Four lipophilicity descriptors (R-M(0), b, C-0 and PCl) for twelve coumarin derivatives were determined by reversed-phase thin-layer chromatography in order to analyze the descriptor which best describes the lipophilicity of the investigated coumarins. Moreover, possible chemical toxicity of coumarins, expressed as the probability of a compound to cause organ-specific health effects, was calculated using ACD/Tox Suite program. The quantitative relationships between toxicity and molecular descriptors, including experimentally determined lipophilicity descriptors obtained in current study were investigated using partial least square regression. The best models were obtained for kidney and liver health effects. Quantitative structure-toxicity relationship models revealed the importance of electric polarization descriptors, size descriptors and lipophilicity descriptors. The obtained models were used for the selection of the structural features of the compounds that are significantly affecting their absorption, distribution, metabolism, excretion and toxicity., Primenom reverzno-fazne tankoslojne hromatografije na dvanaest derivata kumarina određena su četiri parametara lipofilnosti (RM0, b, C0 i PC1). Korelacijom dobijenih rezultata sa izračunatim log P vrednostima utvrđen je deskriptor koji na najbolji način opisuje lipofilnost ispitivanih kumarina. Pored toga izračunata je moguća hemijska toksičnost kumarina, izražena kao verovatnoća uticaja pomenutih jedinjenja na specifične organe (krv, kardiovaskularni sistem, gastrointestinalni sistem, bubrege, jetru i pluća) a koja je izračunata primenom ACD/Tox Suite programa. Dobijene vrednosti toksičnosti korelisane su sa molekulskim deskriptorima i eksperimentalno određenim parametrima lipofilnosti, primenom metode parcijalne regresije najmanjih kvadrata (partial least square regression). Uzimajući u obzir parametre koji opisuju kvalitet modela zavisnosti strukture i toksičnosti, utvrđeno je da su najbolji modeli dobijeni za uticaj kumarina na bubrege i jetru. Svi dobijeni modeli ukazuju na značaj električno polarizacionih deskriptora, kao i deskriptora koji opisuju veličinu i lipofilnost jedinjenja, a upotrebljeni su za utvrđivanje strukturnih karakteristika koje značajno utiču na njihovu apsorpciju, distribuciju, metabolizam, izlučivanje i toksičnost.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters, Analiza zavisnosti strukture i toksičnosti nekih prirodnih i sintetičkih kumarina korišćenjem retencionih parametara",
volume = "77",
number = "10",
pages = "1443-1456",
doi = "10.2298/JSC120716091R"
}
Rabtti, E. H. M. A., Natić, M., Milojković-Opsenica, D., Trifković, J., Tosti, T., Vučković, I., Vajs, V.,& Tešić, Ž.. (2012). Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 77(10), 1443-1456.
https://doi.org/10.2298/JSC120716091R
Rabtti EHMA, Natić M, Milojković-Opsenica D, Trifković J, Tosti T, Vučković I, Vajs V, Tešić Ž. Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters. in Journal of the Serbian Chemical Society. 2012;77(10):1443-1456.
doi:10.2298/JSC120716091R .
Rabtti, El Hadi M. A., Natić, Maja, Milojković-Opsenica, Dušanka, Trifković, Jelena, Tosti, Tomislav, Vučković, Ivan, Vajs, Vlatka, Tešić, Živoslav, "Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters" in Journal of the Serbian Chemical Society, 77, no. 10 (2012):1443-1456,
https://doi.org/10.2298/JSC120716091R . .
4
3
3

RP TLC-Based Lipophilicity Assessment of Some Natural and Synthetic Coumarins

Rabtti, El Hadi M. A.; Natić, Maja; Milojković-Opsenica, Dušanka; Trifković, Jelena; Vučković, Ivan; Vajs, Vlatka; Tešić, Živoslav

(Soc Brasileira Quimica, Sao Paulo, 2012)

TY  - JOUR
AU  - Rabtti, El Hadi M. A.
AU  - Natić, Maja
AU  - Milojković-Opsenica, Dušanka
AU  - Trifković, Jelena
AU  - Vučković, Ivan
AU  - Vajs, Vlatka
AU  - Tešić, Živoslav
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2726
AB  - The lipophilic character of twelve coumarins was investigated by reversed-phase thin-layer chromatography (RP TLC) on RP-18 silica. The three different binary solvent systems composed of water and organic modifier (methanol, tetrahydrofuran or acetonitrile) were used in order to determine retention parameter (R-M(0)) and octanol-water partition coefficient (log P-OW) as a measure of the lipophilicity of the tested compounds. Lipophilicity parameter (log P-OW) was experimentally determined using eight standard solutes with known log P-OW values which were analyzed under the same chromatographic conditions as the target substances. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis (principal component analysis (PCA) and partial least square (PLS) regression) in order to reveal the most influential factors governing the retention, i.e., lipophilicity of the investigated compounds. The quantitative structure-retention relationship models reveal the importance of descriptors which describe the size and the shape of the molecule as well as their polar properties.
PB  - Soc Brasileira Quimica, Sao Paulo
T2  - Journal of the Brazilian Chemical Society
T1  - RP TLC-Based Lipophilicity Assessment of Some Natural and Synthetic Coumarins
VL  - 23
IS  - 3
SP  - 522
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1274
ER  - 
@article{
author = "Rabtti, El Hadi M. A. and Natić, Maja and Milojković-Opsenica, Dušanka and Trifković, Jelena and Vučković, Ivan and Vajs, Vlatka and Tešić, Živoslav",
year = "2012",
abstract = "The lipophilic character of twelve coumarins was investigated by reversed-phase thin-layer chromatography (RP TLC) on RP-18 silica. The three different binary solvent systems composed of water and organic modifier (methanol, tetrahydrofuran or acetonitrile) were used in order to determine retention parameter (R-M(0)) and octanol-water partition coefficient (log P-OW) as a measure of the lipophilicity of the tested compounds. Lipophilicity parameter (log P-OW) was experimentally determined using eight standard solutes with known log P-OW values which were analyzed under the same chromatographic conditions as the target substances. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis (principal component analysis (PCA) and partial least square (PLS) regression) in order to reveal the most influential factors governing the retention, i.e., lipophilicity of the investigated compounds. The quantitative structure-retention relationship models reveal the importance of descriptors which describe the size and the shape of the molecule as well as their polar properties.",
publisher = "Soc Brasileira Quimica, Sao Paulo",
journal = "Journal of the Brazilian Chemical Society",
title = "RP TLC-Based Lipophilicity Assessment of Some Natural and Synthetic Coumarins",
volume = "23",
number = "3",
pages = "522",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1274"
}
Rabtti, E. H. M. A., Natić, M., Milojković-Opsenica, D., Trifković, J., Vučković, I., Vajs, V.,& Tešić, Ž.. (2012). RP TLC-Based Lipophilicity Assessment of Some Natural and Synthetic Coumarins. in Journal of the Brazilian Chemical Society
Soc Brasileira Quimica, Sao Paulo., 23(3), 522.
https://hdl.handle.net/21.15107/rcub_cherry_1274
Rabtti EHMA, Natić M, Milojković-Opsenica D, Trifković J, Vučković I, Vajs V, Tešić Ž. RP TLC-Based Lipophilicity Assessment of Some Natural and Synthetic Coumarins. in Journal of the Brazilian Chemical Society. 2012;23(3):522.
https://hdl.handle.net/21.15107/rcub_cherry_1274 .
Rabtti, El Hadi M. A., Natić, Maja, Milojković-Opsenica, Dušanka, Trifković, Jelena, Vučković, Ivan, Vajs, Vlatka, Tešić, Živoslav, "RP TLC-Based Lipophilicity Assessment of Some Natural and Synthetic Coumarins" in Journal of the Brazilian Chemical Society, 23, no. 3 (2012):522,
https://hdl.handle.net/21.15107/rcub_cherry_1274 .
15
18

Development and validation of a simple thin-layer chromatographic method for the analysis of p-chlorophenol in treated wastewater

Natić, Maja; Dabić, Dragana; Milojković-Opsenica, Dušanka; Dojčinović, Biljana; Roglić, Goran; Manojlović, Dragan; Tešić, Živoslav

(Serbian Chemical Soc, Belgrade, 2012)

TY  - JOUR
AU  - Natić, Maja
AU  - Dabić, Dragana
AU  - Milojković-Opsenica, Dušanka
AU  - Dojčinović, Biljana
AU  - Roglić, Goran
AU  - Manojlović, Dragan
AU  - Tešić, Živoslav
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1055
AB  - A thin-layer chromatographic (TLC) method with densitometric detection was established for the quantification of p-chlorophenol in wastewater. Degradation efficiency of p-chlorophenol was monitored after each treatment of the wastewater samples. Degradation of p-chlorophenol was performed by advanced oxidation processes (AOPs), using UV, H2O2/UV, O3/H2O2/UV, O3 and O3/UV. The developed TLC procedure was found to be simple, rapid and precise. The method is characterized by high sensitivity (the limit of detection was 11 ng per band and limit of quantification 35 ng per band), a linear range from 75 to 500 ng per band, r = 0.9965), and high precision, accuracy (mean percentage recovery 98.6 %), and specificity. Additionally, the efficiency of degradation was monitored using HPLC giving comparable results with the reversed phase TLC measurements.
AB  - Kvantifikacija p-hlorfenola u uzorcima otpadnih voda urađena je primenom tankoslojne hromatografije sa denzitometrijskom detekcijom. Efikasnost degradacije p-hlorfenola praćena je nakon svakog tretmana uzorka otpadne vode. UV svetlost, O3, kao i kombinacija H2O2/UV, O3/H2O2/UV i O3/UV su korišćeni za degradaciju p-hlorfenola. Primenjen TLC postupak je jednostavan, brz i precizan. Visoka osetljivost (limit detekcije je 11 ng po traci i limit kvantifikacije je 35 ng po traci), opseg linearnosti (od 75 do 500 ng po traci, r = 0,9965), visoka preciznost i tačnost, kao i specifičnost su karakteristike korišćenog TLC postupka. HPLC metoda, kao standardna metoda za određivanje p-hlorfenola je takođe primenjena za proučavanje efikasnosti postupka degradacije. Rezultati dobijeni primenom TLC metode su uporedivi sa HPLC merenjima.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Development and validation of a simple thin-layer chromatographic method for the analysis of p-chlorophenol in treated wastewater
T1  - Validacija tankoslojne hromatografije kao metode za jednostavno određivanje p-hlorfenola u tretiranoj otpadnoj vodi
VL  - 77
IS  - 11
SP  - 1649
EP  - 1659
DO  - 10.2298/JSC120509087N
ER  - 
@article{
author = "Natić, Maja and Dabić, Dragana and Milojković-Opsenica, Dušanka and Dojčinović, Biljana and Roglić, Goran and Manojlović, Dragan and Tešić, Živoslav",
year = "2012",
abstract = "A thin-layer chromatographic (TLC) method with densitometric detection was established for the quantification of p-chlorophenol in wastewater. Degradation efficiency of p-chlorophenol was monitored after each treatment of the wastewater samples. Degradation of p-chlorophenol was performed by advanced oxidation processes (AOPs), using UV, H2O2/UV, O3/H2O2/UV, O3 and O3/UV. The developed TLC procedure was found to be simple, rapid and precise. The method is characterized by high sensitivity (the limit of detection was 11 ng per band and limit of quantification 35 ng per band), a linear range from 75 to 500 ng per band, r = 0.9965), and high precision, accuracy (mean percentage recovery 98.6 %), and specificity. Additionally, the efficiency of degradation was monitored using HPLC giving comparable results with the reversed phase TLC measurements., Kvantifikacija p-hlorfenola u uzorcima otpadnih voda urađena je primenom tankoslojne hromatografije sa denzitometrijskom detekcijom. Efikasnost degradacije p-hlorfenola praćena je nakon svakog tretmana uzorka otpadne vode. UV svetlost, O3, kao i kombinacija H2O2/UV, O3/H2O2/UV i O3/UV su korišćeni za degradaciju p-hlorfenola. Primenjen TLC postupak je jednostavan, brz i precizan. Visoka osetljivost (limit detekcije je 11 ng po traci i limit kvantifikacije je 35 ng po traci), opseg linearnosti (od 75 do 500 ng po traci, r = 0,9965), visoka preciznost i tačnost, kao i specifičnost su karakteristike korišćenog TLC postupka. HPLC metoda, kao standardna metoda za određivanje p-hlorfenola je takođe primenjena za proučavanje efikasnosti postupka degradacije. Rezultati dobijeni primenom TLC metode su uporedivi sa HPLC merenjima.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Development and validation of a simple thin-layer chromatographic method for the analysis of p-chlorophenol in treated wastewater, Validacija tankoslojne hromatografije kao metode za jednostavno određivanje p-hlorfenola u tretiranoj otpadnoj vodi",
volume = "77",
number = "11",
pages = "1649-1659",
doi = "10.2298/JSC120509087N"
}
Natić, M., Dabić, D., Milojković-Opsenica, D., Dojčinović, B., Roglić, G., Manojlović, D.,& Tešić, Ž.. (2012). Development and validation of a simple thin-layer chromatographic method for the analysis of p-chlorophenol in treated wastewater. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 77(11), 1649-1659.
https://doi.org/10.2298/JSC120509087N
Natić M, Dabić D, Milojković-Opsenica D, Dojčinović B, Roglić G, Manojlović D, Tešić Ž. Development and validation of a simple thin-layer chromatographic method for the analysis of p-chlorophenol in treated wastewater. in Journal of the Serbian Chemical Society. 2012;77(11):1649-1659.
doi:10.2298/JSC120509087N .
Natić, Maja, Dabić, Dragana, Milojković-Opsenica, Dušanka, Dojčinović, Biljana, Roglić, Goran, Manojlović, Dragan, Tešić, Živoslav, "Development and validation of a simple thin-layer chromatographic method for the analysis of p-chlorophenol in treated wastewater" in Journal of the Serbian Chemical Society, 77, no. 11 (2012):1649-1659,
https://doi.org/10.2298/JSC120509087N . .
1
1

Quantitative structure-retention relationship of new N-substituted 2-alkylidene-4-oxothiazolidines

Dabić, Dragana; Natić, Maja; Džambaski, Zdravko; Marković, Rade; Milojković-Opsenica, Dušanka; Tešić, Živoslav

(Wiley-Blackwell, Malden, 2011)

TY  - JOUR
AU  - Dabić, Dragana
AU  - Natić, Maja
AU  - Džambaski, Zdravko
AU  - Marković, Rade
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/775
AB  - A quantitative structure-retention relationship (QSRR) was built to investigate the relationship between the structural descriptors of 23 newly synthesized N-substituted 2-alkylidene-4-oxothiazolidines and their chromatographic retention. Retention was investigated by means of the reversed-phase thin-layer chromatography (RP-TLC) on the C(18) and CN stationary phases, using methanol, acetonitrile, and tetrahydrofuran as organic modifiers. Full geometry optimization based on the Austin Model 1 (AM1) semi-empirical molecular orbital method was carried out and a set of physicochemical molecular descriptors was calculated from the optimized structures. QSRR was built by means of multiple linear regression (MLR) and partial least squares regression (PLS). The best MLR and PLS models were chosen, on the basis of comparison of the statistical parameters (squared correlation coefficient (R(2)), cross-validated coefficient (R(cv)(2)), and Fischer significance value (F) were used for MLR and the square of the multiple correlation coefficients for the calibration objects (R(2)Y (cum)) and the square of the multiple correlation coefficients for the cross-validation segments (Q(2)Y (cum)) were used for PLS models). Statistically significant and physically meaningful QSRR provided better insight on understanding the retention behavior of the new series of compounds. Lipohilicity (expressed as log P) was included in all MLR and PLS models.
PB  - Wiley-Blackwell, Malden
T2  - Journal of Separation Science
T1  - Quantitative structure-retention relationship of new N-substituted 2-alkylidene-4-oxothiazolidines
VL  - 34
IS  - 18
SP  - 2397
EP  - 2404
DO  - 10.1002/jssc.201100266
ER  - 
@article{
author = "Dabić, Dragana and Natić, Maja and Džambaski, Zdravko and Marković, Rade and Milojković-Opsenica, Dušanka and Tešić, Živoslav",
year = "2011",
abstract = "A quantitative structure-retention relationship (QSRR) was built to investigate the relationship between the structural descriptors of 23 newly synthesized N-substituted 2-alkylidene-4-oxothiazolidines and their chromatographic retention. Retention was investigated by means of the reversed-phase thin-layer chromatography (RP-TLC) on the C(18) and CN stationary phases, using methanol, acetonitrile, and tetrahydrofuran as organic modifiers. Full geometry optimization based on the Austin Model 1 (AM1) semi-empirical molecular orbital method was carried out and a set of physicochemical molecular descriptors was calculated from the optimized structures. QSRR was built by means of multiple linear regression (MLR) and partial least squares regression (PLS). The best MLR and PLS models were chosen, on the basis of comparison of the statistical parameters (squared correlation coefficient (R(2)), cross-validated coefficient (R(cv)(2)), and Fischer significance value (F) were used for MLR and the square of the multiple correlation coefficients for the calibration objects (R(2)Y (cum)) and the square of the multiple correlation coefficients for the cross-validation segments (Q(2)Y (cum)) were used for PLS models). Statistically significant and physically meaningful QSRR provided better insight on understanding the retention behavior of the new series of compounds. Lipohilicity (expressed as log P) was included in all MLR and PLS models.",
publisher = "Wiley-Blackwell, Malden",
journal = "Journal of Separation Science",
title = "Quantitative structure-retention relationship of new N-substituted 2-alkylidene-4-oxothiazolidines",
volume = "34",
number = "18",
pages = "2397-2404",
doi = "10.1002/jssc.201100266"
}
Dabić, D., Natić, M., Džambaski, Z., Marković, R., Milojković-Opsenica, D.,& Tešić, Ž.. (2011). Quantitative structure-retention relationship of new N-substituted 2-alkylidene-4-oxothiazolidines. in Journal of Separation Science
Wiley-Blackwell, Malden., 34(18), 2397-2404.
https://doi.org/10.1002/jssc.201100266
Dabić D, Natić M, Džambaski Z, Marković R, Milojković-Opsenica D, Tešić Ž. Quantitative structure-retention relationship of new N-substituted 2-alkylidene-4-oxothiazolidines. in Journal of Separation Science. 2011;34(18):2397-2404.
doi:10.1002/jssc.201100266 .
Dabić, Dragana, Natić, Maja, Džambaski, Zdravko, Marković, Rade, Milojković-Opsenica, Dušanka, Tešić, Živoslav, "Quantitative structure-retention relationship of new N-substituted 2-alkylidene-4-oxothiazolidines" in Journal of Separation Science, 34, no. 18 (2011):2397-2404,
https://doi.org/10.1002/jssc.201100266 . .
21
21
22

Estimation of lipophilicity of n-substituted 2-alkylidene-4-oxothiazolidines by means of reversed-phase thin-layer chromatography

Dabić, Dragana; Natić, Maja; Džambaski, Zdravko; Stojanović, Milovan; Marković, Rade; Milojković-Opsenica, Dušanka; Tešić, Živoslav

(Taylor & Francis Inc, Philadelphia, 2011)

TY  - JOUR
AU  - Dabić, Dragana
AU  - Natić, Maja
AU  - Džambaski, Zdravko
AU  - Stojanović, Milovan
AU  - Marković, Rade
AU  - Milojković-Opsenica, Dušanka
AU  - Tešić, Živoslav
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/897
AB  - The chromatographic behavior of 23 new 2-alkylidene-4-oxothiazolidine derivatives was investigated by means of the reversed-phase thin-layer chromatography (RP TLC) on the C18 and CN stationary phases. Binary mixtures of methanol-water, acetonitrile-water, and tetrahydrofuran-water were used as mobile phases. Linear relationships between the volume fraction of the organic mobile phase modifier and the RM values were established for each solute with high correlation coefficient values (r0.99). The investigated 4-oxothiazolidines are a congeneric set of compounds, and significant correlations were obtained between the chromatographically determined [image omitted] and m values. The lipophilicity parameters obtained from the reversed-phase experiments were compared with the calculated log P values. Some of these correlations offer very good predicting models, which are important for a better understanding of the relationships between chemical structure and retention, and can prove helpful in the structure-activity studies as well. Finally, our investigation was focused on chemometric processing of the retention data in different chromatographic systems. To this effect, Principal Component Analysis (PCA) was performed, yielding the results helpful in interpretation of interactions among investigated substances, binary mobile phases, and the two different stationary phases.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Liquid Chromatography & Related Technologies
T1  - Estimation of lipophilicity of n-substituted 2-alkylidene-4-oxothiazolidines by means of reversed-phase thin-layer chromatography
VL  - 34
IS  - 10-11
SP  - 791
EP  - 804
DO  - 10.1080/10826076.2011.571157
ER  - 
@article{
author = "Dabić, Dragana and Natić, Maja and Džambaski, Zdravko and Stojanović, Milovan and Marković, Rade and Milojković-Opsenica, Dušanka and Tešić, Živoslav",
year = "2011",
abstract = "The chromatographic behavior of 23 new 2-alkylidene-4-oxothiazolidine derivatives was investigated by means of the reversed-phase thin-layer chromatography (RP TLC) on the C18 and CN stationary phases. Binary mixtures of methanol-water, acetonitrile-water, and tetrahydrofuran-water were used as mobile phases. Linear relationships between the volume fraction of the organic mobile phase modifier and the RM values were established for each solute with high correlation coefficient values (r0.99). The investigated 4-oxothiazolidines are a congeneric set of compounds, and significant correlations were obtained between the chromatographically determined [image omitted] and m values. The lipophilicity parameters obtained from the reversed-phase experiments were compared with the calculated log P values. Some of these correlations offer very good predicting models, which are important for a better understanding of the relationships between chemical structure and retention, and can prove helpful in the structure-activity studies as well. Finally, our investigation was focused on chemometric processing of the retention data in different chromatographic systems. To this effect, Principal Component Analysis (PCA) was performed, yielding the results helpful in interpretation of interactions among investigated substances, binary mobile phases, and the two different stationary phases.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Liquid Chromatography & Related Technologies",
title = "Estimation of lipophilicity of n-substituted 2-alkylidene-4-oxothiazolidines by means of reversed-phase thin-layer chromatography",
volume = "34",
number = "10-11",
pages = "791-804",
doi = "10.1080/10826076.2011.571157"
}
Dabić, D., Natić, M., Džambaski, Z., Stojanović, M., Marković, R., Milojković-Opsenica, D.,& Tešić, Ž.. (2011). Estimation of lipophilicity of n-substituted 2-alkylidene-4-oxothiazolidines by means of reversed-phase thin-layer chromatography. in Journal of Liquid Chromatography & Related Technologies
Taylor & Francis Inc, Philadelphia., 34(10-11), 791-804.
https://doi.org/10.1080/10826076.2011.571157
Dabić D, Natić M, Džambaski Z, Stojanović M, Marković R, Milojković-Opsenica D, Tešić Ž. Estimation of lipophilicity of n-substituted 2-alkylidene-4-oxothiazolidines by means of reversed-phase thin-layer chromatography. in Journal of Liquid Chromatography & Related Technologies. 2011;34(10-11):791-804.
doi:10.1080/10826076.2011.571157 .
Dabić, Dragana, Natić, Maja, Džambaski, Zdravko, Stojanović, Milovan, Marković, Rade, Milojković-Opsenica, Dušanka, Tešić, Živoslav, "Estimation of lipophilicity of n-substituted 2-alkylidene-4-oxothiazolidines by means of reversed-phase thin-layer chromatography" in Journal of Liquid Chromatography & Related Technologies, 34, no. 10-11 (2011):791-804,
https://doi.org/10.1080/10826076.2011.571157 . .
9
9
9

Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography

Andrić, Filip; Trifković, Jelena; Radoičić, Aleksandra D.; Šegan, Sandra; Tešić, Živoslav; Milojković-Opsenica, Dušanka

(Oxford : Pergamon-Elsevier Science Ltd, 2010)

TY  - JOUR
AU  - Andrić, Filip
AU  - Trifković, Jelena
AU  - Radoičić, Aleksandra D.
AU  - Šegan, Sandra
AU  - Tešić, Živoslav
AU  - Milojković-Opsenica, Dušanka
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/707
AB  - In order to determine the soil-water partition coefficient for eleven mono- and poly-substituted phenolic compounds, for which there is still no literature data available. the possibility of using thin-layer chromatography (TLC) as a means for rapid and reliable log K-OC estimation was examined A series of chromatographically derived descriptors R-M(0), b, C-0 and PC1 (first principal component), calculated from retention data obtained under reversed-phase conditions, were used for the assessment of models as well as for a direct calibration procedure The final calibration models are discussed with regard to the achieved accuracy and statistical quality, the type of descriptors used and the corresponding chromatographic conditions The estimated log K-OC values of the studied phenols were compared with those obtained by other means (a) the present OECD guideline based on an HPLC technique, (b) the KOCWIN software package, available free of charge from the US Environmental Protection Agency web site and
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Chemosphere
T1  - Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography
VL  - 81
IS  - 3
SP  - 299
EP  - 305
DO  - 10.1016/j.chemosphere.2010.07.049
ER  - 
@article{
author = "Andrić, Filip and Trifković, Jelena and Radoičić, Aleksandra D. and Šegan, Sandra and Tešić, Živoslav and Milojković-Opsenica, Dušanka",
year = "2010",
abstract = "In order to determine the soil-water partition coefficient for eleven mono- and poly-substituted phenolic compounds, for which there is still no literature data available. the possibility of using thin-layer chromatography (TLC) as a means for rapid and reliable log K-OC estimation was examined A series of chromatographically derived descriptors R-M(0), b, C-0 and PC1 (first principal component), calculated from retention data obtained under reversed-phase conditions, were used for the assessment of models as well as for a direct calibration procedure The final calibration models are discussed with regard to the achieved accuracy and statistical quality, the type of descriptors used and the corresponding chromatographic conditions The estimated log K-OC values of the studied phenols were compared with those obtained by other means (a) the present OECD guideline based on an HPLC technique, (b) the KOCWIN software package, available free of charge from the US Environmental Protection Agency web site and",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Chemosphere",
title = "Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography",
volume = "81",
number = "3",
pages = "299-305",
doi = "10.1016/j.chemosphere.2010.07.049"
}
Andrić, F., Trifković, J., Radoičić, A. D., Šegan, S., Tešić, Ž.,& Milojković-Opsenica, D.. (2010). Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography. in Chemosphere
Oxford : Pergamon-Elsevier Science Ltd., 81(3), 299-305.
https://doi.org/10.1016/j.chemosphere.2010.07.049
Andrić F, Trifković J, Radoičić AD, Šegan S, Tešić Ž, Milojković-Opsenica D. Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography. in Chemosphere. 2010;81(3):299-305.
doi:10.1016/j.chemosphere.2010.07.049 .
Andrić, Filip, Trifković, Jelena, Radoičić, Aleksandra D., Šegan, Sandra, Tešić, Živoslav, Milojković-Opsenica, Dušanka, "Determination of the soil-water partition coefficients (log K-OC) of some mono- and poly-substituted phenols by reversed-phase thin-layer chromatography" in Chemosphere, 81, no. 3 (2010):299-305,
https://doi.org/10.1016/j.chemosphere.2010.07.049 . .
15
12
16

Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity

Grgurić-Šipka, Sanja; Ivanovic, Ivanka; Rakic, Gordana; Todorović, Nina; Gligorijević, Nevenka; Radulovic, Sinisa; Arion, Vladimir B.; Keppler, Bernhard K.; Tešić, Živoslav

(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2010)

TY  - JOUR
AU  - Grgurić-Šipka, Sanja
AU  - Ivanovic, Ivanka
AU  - Rakic, Gordana
AU  - Todorović, Nina
AU  - Gligorijević, Nevenka
AU  - Radulovic, Sinisa
AU  - Arion, Vladimir B.
AU  - Keppler, Bernhard K.
AU  - Tešić, Živoslav
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/646
AB  - Ruthenium(II)-arene complexes of general formulae [(eta(6)-p-cymene)Ru(L1-3)Cl-2], where L1-3 is 3-acetylpyridine (1), 4-acetylpyridine (2) and 2-amino-5-chloropyridine (3), Correspondingly, [(eta(6)-p-cymene)Ru(HL4,5)Cl-2], where HL4 and HL5 are respectively isonicotinic acid (4) and nicotinic acid (5) and [(eta(6)-p-cymene)Ru(HL6-9)Cl], where H2L6-9 represent 2,3-pyridinedicarboxylic acid (6), 2,4-pyidinedicarboxylic acid (7), 2,5-pyridinedicarboxylic acid (8) and 2,6-pyridinedicarboxylic acid (9), were prepared by the reaction of (eta(6)-p-cymene)(2)RuCl2](2) (10) with the corresponding ligand in 1:2 molar ratio in isopropanol. The complexes were characterized by elemental analysis, mass spectrometry, IR and NMR spectroscopies. According to these data the molecules adopt the usual "three-leg piano-stool" geometry which is common for this type of complexes. The structures of I and 7 were determined by X-ray crystallography. The complexes revealed low antiproliferative activity in six investigated tumor cell lines (HeLa, B16, FemX, MDA-MB-361, MDA-MB-453 and LS-174). The reaction of 6 with 9-methyladenine was studied by H-1 NMR, H-1, H-1 COSY and H-1, H-1 NOESY spectroscopy.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux
T2  - European Journal of Medicinal Chemistry
T1  - Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity
VL  - 45
IS  - 3
SP  - 1051
EP  - 1058
DO  - 10.1016/j.ejmech.2009.11.055
ER  - 
@article{
author = "Grgurić-Šipka, Sanja and Ivanovic, Ivanka and Rakic, Gordana and Todorović, Nina and Gligorijević, Nevenka and Radulovic, Sinisa and Arion, Vladimir B. and Keppler, Bernhard K. and Tešić, Živoslav",
year = "2010",
abstract = "Ruthenium(II)-arene complexes of general formulae [(eta(6)-p-cymene)Ru(L1-3)Cl-2], where L1-3 is 3-acetylpyridine (1), 4-acetylpyridine (2) and 2-amino-5-chloropyridine (3), Correspondingly, [(eta(6)-p-cymene)Ru(HL4,5)Cl-2], where HL4 and HL5 are respectively isonicotinic acid (4) and nicotinic acid (5) and [(eta(6)-p-cymene)Ru(HL6-9)Cl], where H2L6-9 represent 2,3-pyridinedicarboxylic acid (6), 2,4-pyidinedicarboxylic acid (7), 2,5-pyridinedicarboxylic acid (8) and 2,6-pyridinedicarboxylic acid (9), were prepared by the reaction of (eta(6)-p-cymene)(2)RuCl2](2) (10) with the corresponding ligand in 1:2 molar ratio in isopropanol. The complexes were characterized by elemental analysis, mass spectrometry, IR and NMR spectroscopies. According to these data the molecules adopt the usual "three-leg piano-stool" geometry which is common for this type of complexes. The structures of I and 7 were determined by X-ray crystallography. The complexes revealed low antiproliferative activity in six investigated tumor cell lines (HeLa, B16, FemX, MDA-MB-361, MDA-MB-453 and LS-174). The reaction of 6 with 9-methyladenine was studied by H-1 NMR, H-1, H-1 COSY and H-1, H-1 NOESY spectroscopy.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux",
journal = "European Journal of Medicinal Chemistry",
title = "Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity",
volume = "45",
number = "3",
pages = "1051-1058",
doi = "10.1016/j.ejmech.2009.11.055"
}
Grgurić-Šipka, S., Ivanovic, I., Rakic, G., Todorović, N., Gligorijević, N., Radulovic, S., Arion, V. B., Keppler, B. K.,& Tešić, Ž.. (2010). Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux., 45(3), 1051-1058.
https://doi.org/10.1016/j.ejmech.2009.11.055
Grgurić-Šipka S, Ivanovic I, Rakic G, Todorović N, Gligorijević N, Radulovic S, Arion VB, Keppler BK, Tešić Ž. Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity. in European Journal of Medicinal Chemistry. 2010;45(3):1051-1058.
doi:10.1016/j.ejmech.2009.11.055 .
Grgurić-Šipka, Sanja, Ivanovic, Ivanka, Rakic, Gordana, Todorović, Nina, Gligorijević, Nevenka, Radulovic, Sinisa, Arion, Vladimir B., Keppler, Bernhard K., Tešić, Živoslav, "Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity" in European Journal of Medicinal Chemistry, 45, no. 3 (2010):1051-1058,
https://doi.org/10.1016/j.ejmech.2009.11.055 . .
75
67
78

Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro

Atrrog, A.A.B.; Natić, Maja; Tosti, Tomislav; Milojković-Opsenica, Dušanka; Dordević, I.; Tešević, Vele; Jadranin, Milka; Milosavljević, Slobodan; Lazić, M.; Radulović, Siniša; Tešić, Živoslav

(2009)

TY  - JOUR
AU  - Atrrog, A.A.B.
AU  - Natić, Maja
AU  - Tosti, Tomislav
AU  - Milojković-Opsenica, Dušanka
AU  - Dordević, I.
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Milosavljević, Slobodan
AU  - Lazić, M.
AU  - Radulović, Siniša
AU  - Tešić, Živoslav
PY  - 2009
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/567
AB  - In this study 10 guaianolide-type sesquiterpene γ-lactones named amphoricarpolides, isolated from the aerial parts of two endemic subspecies of Amphoricarpos neumayeri (ssp. neumayeri and ssp. murbeckii Bosnjak), were investigated by means of reversed-phase thin-layer chromatography. Methanol-water and tetrahydrofuran-water binary mixtures were used as mobile phase in order to determine lipophilicity parameters and C0. Some of the investigated compounds were screened for their cytotoxic activity against HeLa and B16 cells. Chromatographically obtained lipophilicity parameters were correlated with calculated logP values and IC50 values. Principal component analysis identified the dominant pattern in the chromatographically obtained data. Copyright
T2  - Biomedical Chromatography
T1  - Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro
VL  - 23
IS  - 3
SP  - 250
EP  - 256
DO  - 10.1002/bmc.1091
ER  - 
@article{
author = "Atrrog, A.A.B. and Natić, Maja and Tosti, Tomislav and Milojković-Opsenica, Dušanka and Dordević, I. and Tešević, Vele and Jadranin, Milka and Milosavljević, Slobodan and Lazić, M. and Radulović, Siniša and Tešić, Živoslav",
year = "2009",
abstract = "In this study 10 guaianolide-type sesquiterpene γ-lactones named amphoricarpolides, isolated from the aerial parts of two endemic subspecies of Amphoricarpos neumayeri (ssp. neumayeri and ssp. murbeckii Bosnjak), were investigated by means of reversed-phase thin-layer chromatography. Methanol-water and tetrahydrofuran-water binary mixtures were used as mobile phase in order to determine lipophilicity parameters and C0. Some of the investigated compounds were screened for their cytotoxic activity against HeLa and B16 cells. Chromatographically obtained lipophilicity parameters were correlated with calculated logP values and IC50 values. Principal component analysis identified the dominant pattern in the chromatographically obtained data. Copyright",
journal = "Biomedical Chromatography",
title = "Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro",
volume = "23",
number = "3",
pages = "250-256",
doi = "10.1002/bmc.1091"
}
Atrrog, A.A.B., Natić, M., Tosti, T., Milojković-Opsenica, D., Dordević, I., Tešević, V., Jadranin, M., Milosavljević, S., Lazić, M., Radulović, S.,& Tešić, Ž.. (2009). Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro. in Biomedical Chromatography, 23(3), 250-256.
https://doi.org/10.1002/bmc.1091
Atrrog A, Natić M, Tosti T, Milojković-Opsenica D, Dordević I, Tešević V, Jadranin M, Milosavljević S, Lazić M, Radulović S, Tešić Ž. Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro. in Biomedical Chromatography. 2009;23(3):250-256.
doi:10.1002/bmc.1091 .
Atrrog, A.A.B., Natić, Maja, Tosti, Tomislav, Milojković-Opsenica, Dušanka, Dordević, I., Tešević, Vele, Jadranin, Milka, Milosavljević, Slobodan, Lazić, M., Radulović, Siniša, Tešić, Živoslav, "Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro" in Biomedical Chromatography, 23, no. 3 (2009):250-256,
https://doi.org/10.1002/bmc.1091 . .
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21

TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents

Tosti, Tomislav; Rakić, Gordana; Natić, Maja; Milojković-Opsenica, Dušanka; Husinec, Suren; Savić, Vladimir; Tešić, Živoslav

(Akademiai Kiado Zrt, Budapest, 2009)

TY  - JOUR
AU  - Tosti, Tomislav
AU  - Rakić, Gordana
AU  - Natić, Maja
AU  - Milojković-Opsenica, Dušanka
AU  - Husinec, Suren
AU  - Savić, Vladimir
AU  - Tešić, Živoslav
PY  - 2009
UR  - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1199
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3508
AB  - The chromatographic behavior of three biocidal technical materials, rodenticide active ingredients brodifacoum, bromadiolone, and coumatetralyl, and impurities present in the technical material was investigated by both normal-phase (NP) and reversed-phase (RP) planar chromatography. The research was carried out using thin-layers of silica gel, alumina, cellulose, and C-18 silica. Several solvents on their own or in various combinations and proportions were used for separation. The optimum chromatographic systems for separation of the substances from each other and from their impurities were selected. Under reversed-phase chromatographic (RPC) conditions a linear correlation between R-M values and mobile phase composition was established. From results obtained, the lipophilicity R-M(o) and C-0 were determined. Possible separation mechanisms are discussed on the basis of the established retention behavior.
PB  - Akademiai Kiado Zrt, Budapest
T2  - Journal of Planar Chromatography - Modern TLC
T1  - TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents
VL  - 22
IS  - 5
SP  - 333
EP  - 343
DO  - 10.1556/JPC.22.2009.5.4
ER  - 
@article{
author = "Tosti, Tomislav and Rakić, Gordana and Natić, Maja and Milojković-Opsenica, Dušanka and Husinec, Suren and Savić, Vladimir and Tešić, Živoslav",
year = "2009",
abstract = "The chromatographic behavior of three biocidal technical materials, rodenticide active ingredients brodifacoum, bromadiolone, and coumatetralyl, and impurities present in the technical material was investigated by both normal-phase (NP) and reversed-phase (RP) planar chromatography. The research was carried out using thin-layers of silica gel, alumina, cellulose, and C-18 silica. Several solvents on their own or in various combinations and proportions were used for separation. The optimum chromatographic systems for separation of the substances from each other and from their impurities were selected. Under reversed-phase chromatographic (RPC) conditions a linear correlation between R-M values and mobile phase composition was established. From results obtained, the lipophilicity R-M(o) and C-0 were determined. Possible separation mechanisms are discussed on the basis of the established retention behavior.",
publisher = "Akademiai Kiado Zrt, Budapest",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents",
volume = "22",
number = "5",
pages = "333-343",
doi = "10.1556/JPC.22.2009.5.4"
}
Tosti, T., Rakić, G., Natić, M., Milojković-Opsenica, D., Husinec, S., Savić, V.,& Tešić, Ž.. (2009). TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents. in Journal of Planar Chromatography - Modern TLC
Akademiai Kiado Zrt, Budapest., 22(5), 333-343.
https://doi.org/10.1556/JPC.22.2009.5.4
Tosti T, Rakić G, Natić M, Milojković-Opsenica D, Husinec S, Savić V, Tešić Ž. TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents. in Journal of Planar Chromatography - Modern TLC. 2009;22(5):333-343.
doi:10.1556/JPC.22.2009.5.4 .
Tosti, Tomislav, Rakić, Gordana, Natić, Maja, Milojković-Opsenica, Dušanka, Husinec, Suren, Savić, Vladimir, Tešić, Živoslav, "TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents" in Journal of Planar Chromatography - Modern TLC, 22, no. 5 (2009):333-343,
https://doi.org/10.1556/JPC.22.2009.5.4 . .
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4

Relationships between structure, retention and biological activity of some Schiff base ligands and their complexes

Baošić, R.; Radojević, A.; Radulović, Milanka; Miletić, Srđan; Natić, Maja; Tešić, Živoslav

(2008)

TY  - JOUR
AU  - Baošić, R.
AU  - Radojević, A.
AU  - Radulović, Milanka
AU  - Miletić, Srđan
AU  - Natić, Maja
AU  - Tešić, Živoslav
PY  - 2008
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/474
AB  - The lipophilicity of a series of Schiff base ligands and their complexes with nickel(II) and copper(II) has been determined by reversed-phase thin-layer chromatography using binary dioxane-water mobile phase. Chelate ligands were prepared by condensation of diamine and the corresponding β-diketone. Copper(II) and nickel(II) complexes with chelate ligands containing ethane-1,2-diamine or propane-1,2-diamine as the amine part and pentane-2,4-dione and/or 1-phenylbutane-1,3-dione, pentane-2,4-dione and/or 1,1,1-trifluoropentane-2,4-dione, or 1,1,1-trifluoropentane-2,4-dione and/or 1-phenylbutane-1,3-dione as the β-diketone part were synthesized. Some of investigated compounds were screened for their in vitro antifungal activity against Sacharomyces cerevisiae and antibacterial activity against Escherichia coli. Chromatographically obtained lipophilicity parameters were correlated both with calculated n-octanol-water partition coefficient C log P and antimicrobial activities. Satisfactory correlations were obtained. Chromatographic data proved to be reliable parameters for describing the lipophilic properties of the investigated compounds. Additionally, the principal components analysis was performed on the data chromatographically obtained. This statistical method was useful for distinguishing compounds and objective comparison of their lipophilicity parameters. Copyright
T2  - Biomedical Chromatography
T1  - Relationships between structure, retention and biological activity of some Schiff base ligands and their complexes
VL  - 22
IS  - 4
SP  - 379
EP  - 386
DO  - 10.1002/bmc.943
ER  - 
@article{
author = "Baošić, R. and Radojević, A. and Radulović, Milanka and Miletić, Srđan and Natić, Maja and Tešić, Živoslav",
year = "2008",
abstract = "The lipophilicity of a series of Schiff base ligands and their complexes with nickel(II) and copper(II) has been determined by reversed-phase thin-layer chromatography using binary dioxane-water mobile phase. Chelate ligands were prepared by condensation of diamine and the corresponding β-diketone. Copper(II) and nickel(II) complexes with chelate ligands containing ethane-1,2-diamine or propane-1,2-diamine as the amine part and pentane-2,4-dione and/or 1-phenylbutane-1,3-dione, pentane-2,4-dione and/or 1,1,1-trifluoropentane-2,4-dione, or 1,1,1-trifluoropentane-2,4-dione and/or 1-phenylbutane-1,3-dione as the β-diketone part were synthesized. Some of investigated compounds were screened for their in vitro antifungal activity against Sacharomyces cerevisiae and antibacterial activity against Escherichia coli. Chromatographically obtained lipophilicity parameters were correlated both with calculated n-octanol-water partition coefficient C log P and antimicrobial activities. Satisfactory correlations were obtained. Chromatographic data proved to be reliable parameters for describing the lipophilic properties of the investigated compounds. Additionally, the principal components analysis was performed on the data chromatographically obtained. This statistical method was useful for distinguishing compounds and objective comparison of their lipophilicity parameters. Copyright",
journal = "Biomedical Chromatography",
title = "Relationships between structure, retention and biological activity of some Schiff base ligands and their complexes",
volume = "22",
number = "4",
pages = "379-386",
doi = "10.1002/bmc.943"
}
Baošić, R., Radojević, A., Radulović, M., Miletić, S., Natić, M.,& Tešić, Ž.. (2008). Relationships between structure, retention and biological activity of some Schiff base ligands and their complexes. in Biomedical Chromatography, 22(4), 379-386.
https://doi.org/10.1002/bmc.943
Baošić R, Radojević A, Radulović M, Miletić S, Natić M, Tešić Ž. Relationships between structure, retention and biological activity of some Schiff base ligands and their complexes. in Biomedical Chromatography. 2008;22(4):379-386.
doi:10.1002/bmc.943 .
Baošić, R., Radojević, A., Radulović, Milanka, Miletić, Srđan, Natić, Maja, Tešić, Živoslav, "Relationships between structure, retention and biological activity of some Schiff base ligands and their complexes" in Biomedical Chromatography, 22, no. 4 (2008):379-386,
https://doi.org/10.1002/bmc.943 . .
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The effect of the structure of mixed tetraoxanes on their chromatographic behavior on different adsorbents

Gaica, Sandra; Opsenica, Dejan; Šolaja, Bogdan; Tešić, Živoslav; Milojković-Opsenica, Dušanka

(Research Inst Medicinal Plants, Budakalasz, 2004)

TY  - JOUR
AU  - Gaica, Sandra
AU  - Opsenica, Dejan
AU  - Šolaja, Bogdan
AU  - Tešić, Živoslav
AU  - Milojković-Opsenica, Dušanka
PY  - 2004
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2835
AB  - The retention behavior of 29 biologically active compounds, mixed 1,2,4,5-tetraoxanes, has been investigated by thin-layer chromatography on unmodified silica, CN-silica, and RP-18-silica. The binary mobile phases ethyl acetate-petroleum ether and ethyl acetate-toluene were used under normal-phase conditions and water-organic modifier (methanol, acetone, dioxane) under reversed-phase conditions. For normal-phase conditions R-F values were plotted against the amount [%, v/v] of more polar component in the mobile phase. For reversed-phase conditions R-M values were calculated and plotted against the amount [%, v/v] of organic modifier in the mobile phase. On the basis of the results obtained the effects of the structures of the compounds on their retention were studied. Retention mechanisms are discussed for all the separations.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
T1  - The effect of the structure of mixed tetraoxanes on their chromatographic behavior on different adsorbents
VL  - 17
IS  - 5
SP  - 342
EP  - 349
DO  - 10.1556/JPC.17.2004.5.4
ER  - 
@article{
author = "Gaica, Sandra and Opsenica, Dejan and Šolaja, Bogdan and Tešić, Živoslav and Milojković-Opsenica, Dušanka",
year = "2004",
abstract = "The retention behavior of 29 biologically active compounds, mixed 1,2,4,5-tetraoxanes, has been investigated by thin-layer chromatography on unmodified silica, CN-silica, and RP-18-silica. The binary mobile phases ethyl acetate-petroleum ether and ethyl acetate-toluene were used under normal-phase conditions and water-organic modifier (methanol, acetone, dioxane) under reversed-phase conditions. For normal-phase conditions R-F values were plotted against the amount [%, v/v] of more polar component in the mobile phase. For reversed-phase conditions R-M values were calculated and plotted against the amount [%, v/v] of organic modifier in the mobile phase. On the basis of the results obtained the effects of the structures of the compounds on their retention were studied. Retention mechanisms are discussed for all the separations.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography",
title = "The effect of the structure of mixed tetraoxanes on their chromatographic behavior on different adsorbents",
volume = "17",
number = "5",
pages = "342-349",
doi = "10.1556/JPC.17.2004.5.4"
}
Gaica, S., Opsenica, D., Šolaja, B., Tešić, Ž.,& Milojković-Opsenica, D.. (2004). The effect of the structure of mixed tetraoxanes on their chromatographic behavior on different adsorbents. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography
Research Inst Medicinal Plants, Budakalasz., 17(5), 342-349.
https://doi.org/10.1556/JPC.17.2004.5.4
Gaica S, Opsenica D, Šolaja B, Tešić Ž, Milojković-Opsenica D. The effect of the structure of mixed tetraoxanes on their chromatographic behavior on different adsorbents. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2004;17(5):342-349.
doi:10.1556/JPC.17.2004.5.4 .
Gaica, Sandra, Opsenica, Dejan, Šolaja, Bogdan, Tešić, Živoslav, Milojković-Opsenica, Dušanka, "The effect of the structure of mixed tetraoxanes on their chromatographic behavior on different adsorbents" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 17, no. 5 (2004):342-349,
https://doi.org/10.1556/JPC.17.2004.5.4 . .
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