TY  - JOUR
AU  - Avramov Ivić, Milka
AU  - Petrović, Slobodan D.
AU  - Vonmoos, F.
AU  - Mijin, Dušan
AU  - Živković, Predrag M.
AU  - Drljevic, K. M.
PY  - 2008
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/377
AB  - The aim of the present study was to examine the behavior of commercial clarithromycin, Clathrocyn (R), comparing to the results previously obtained using pure clarithromycin under the same experimental conditions. The study was performed by cyclic linear sweep voltammetry and the bulk of electrolyte was analyzed by FTIR spectroscopy and HPLC. At gold electrode, in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, the electrochemical determination of pure clarithromycin was previously defined by four anodic and one cathodic reproductive peaks, and commercial clarithromycin is defined by reproductive one anodic peak which appears from 0.60 to 0.80 V vs. SCE. Previously, FTIR analysis of the bulk electrolyte showed the apparent changes in pure clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds. FTIR analysis of the bulk electrolyte also showed changes in the molecule structure in commercial-tablets form of clarithromycin: indicating disappearance of lactone structure and changes of carbonyl group at position 9.
PB  - Pleiades Publishing Inc, Moscow
T2  - Russian Journal of Electrochemistry
T1  - The electrochemical behavior of commercial clarithromycin and spectroscopic detection of its structural changes
VL  - 44
IS  - 8
SP  - 931
EP  - 936
DO  - 10.1134/S1023193508080089
ER  - 

@article{
author = "Avramov Ivić, Milka and Petrović, Slobodan D. and Vonmoos, F. and Mijin, Dušan and Živković, Predrag M. and Drljevic, K. M.",
year = "2008",
abstract = "The aim of the present study was to examine the behavior of commercial clarithromycin, Clathrocyn (R), comparing to the results previously obtained using pure clarithromycin under the same experimental conditions. The study was performed by cyclic linear sweep voltammetry and the bulk of electrolyte was analyzed by FTIR spectroscopy and HPLC. At gold electrode, in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, the electrochemical determination of pure clarithromycin was previously defined by four anodic and one cathodic reproductive peaks, and commercial clarithromycin is defined by reproductive one anodic peak which appears from 0.60 to 0.80 V vs. SCE. Previously, FTIR analysis of the bulk electrolyte showed the apparent changes in pure clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds. FTIR analysis of the bulk electrolyte also showed changes in the molecule structure in commercial-tablets form of clarithromycin: indicating disappearance of lactone structure and changes of carbonyl group at position 9.",
publisher = "Pleiades Publishing Inc, Moscow",
journal = "Russian Journal of Electrochemistry",
title = "The electrochemical behavior of commercial clarithromycin and spectroscopic detection of its structural changes",
volume = "44",
number = "8",
pages = "931-936",
doi = "10.1134/S1023193508080089"
}

Avramov Ivić, M., Petrović, S. D., Vonmoos, F., Mijin, D., Živković, P. M.,& Drljevic, K. M.. (2008). The electrochemical behavior of commercial clarithromycin and spectroscopic detection of its structural changes. in Russian Journal of Electrochemistry
Pleiades Publishing Inc, Moscow., 44(8), 931-936.
https://doi.org/10.1134/S1023193508080089

Avramov Ivić M, Petrović SD, Vonmoos F, Mijin D, Živković PM, Drljevic KM. The electrochemical behavior of commercial clarithromycin and spectroscopic detection of its structural changes. in Russian Journal of Electrochemistry. 2008;44(8):931-936.
doi:10.1134/S1023193508080089 .

Avramov Ivić, Milka, Petrović, Slobodan D., Vonmoos, F., Mijin, Dušan, Živković, Predrag M., Drljevic, K. M., "The electrochemical behavior of commercial clarithromycin and spectroscopic detection of its structural changes" in Russian Journal of Electrochemistry, 44, no. 8 (2008):931-936,
https://doi.org/10.1134/S1023193508080089 . .

TY  - JOUR
AU  - Avramov Ivić, Milka
AU  - Petrović, Slobodan D.
AU  - Vonmoos, F.
AU  - Mijin, Dušan
AU  - Živković, Predrag M.
AU  - Drljević, Katica M.
PY  - 2007
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4256
AB  - The aim of the present study was the qualitative determination of the pure clarithromycin using a gold electrode in neutral electrolyte by cyclic linear sweep voltammetry. It was shown that in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, a gold electrode is successfully employed for the qualitative determination of clarithromycin by detection of the reproductive four anodic and one cathodic peaks. After the potentiostatic measurements at the potential values corresponded to current peaks, the bulk electrolyte was analyzed by FTIR spectroscopy to show the changes in molecular structure of clarithromycin. FTIR analysis of the bulk electrolyte after 4 h of holding the potential at -0.61 V vs. SCE (cathodic peak) showed the apparent changes in clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds.
PB  - Elsevier
T2  - Electrochemistry Communications
T1  - The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode
VL  - 9
IS  - 7
SP  - 1643
EP  - 1647
DO  - 10.1016/j.elecom.2007.03.011
ER  - 

@article{
author = "Avramov Ivić, Milka and Petrović, Slobodan D. and Vonmoos, F. and Mijin, Dušan and Živković, Predrag M. and Drljević, Katica M.",
year = "2007",
abstract = "The aim of the present study was the qualitative determination of the pure clarithromycin using a gold electrode in neutral electrolyte by cyclic linear sweep voltammetry. It was shown that in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, a gold electrode is successfully employed for the qualitative determination of clarithromycin by detection of the reproductive four anodic and one cathodic peaks. After the potentiostatic measurements at the potential values corresponded to current peaks, the bulk electrolyte was analyzed by FTIR spectroscopy to show the changes in molecular structure of clarithromycin. FTIR analysis of the bulk electrolyte after 4 h of holding the potential at -0.61 V vs. SCE (cathodic peak) showed the apparent changes in clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds.",
publisher = "Elsevier",
journal = "Electrochemistry Communications",
title = "The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode",
volume = "9",
number = "7",
pages = "1643-1647",
doi = "10.1016/j.elecom.2007.03.011"
}

Avramov Ivić, M., Petrović, S. D., Vonmoos, F., Mijin, D., Živković, P. M.,& Drljević, K. M.. (2007). The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode. in Electrochemistry Communications
Elsevier., 9(7), 1643-1647.
https://doi.org/10.1016/j.elecom.2007.03.011

Avramov Ivić M, Petrović SD, Vonmoos F, Mijin D, Živković PM, Drljević KM. The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode. in Electrochemistry Communications. 2007;9(7):1643-1647.
doi:10.1016/j.elecom.2007.03.011 .

Avramov Ivić, Milka, Petrović, Slobodan D., Vonmoos, F., Mijin, Dušan, Živković, Predrag M., Drljević, Katica M., "The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode" in Electrochemistry Communications, 9, no. 7 (2007):1643-1647,
https://doi.org/10.1016/j.elecom.2007.03.011 . .