TY  - JOUR
AU  - Aćimović, Milica
AU  - Zorić, Miroslav
AU  - Zheljazkov, Valtcho
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Stanković Jeremić, Jovana
AU  - Cvetković, Mirjana
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3952
AB  - The objective of this study was to evaluate wild growing Satureja kitaibelii, Thymus serpyllum,
Origanum vulgare, Achillea millefolium and Achillea clypeolata with respect to their essential oil (EO)
content, composition and antimicrobial activity. The five species were collected at Mt. Rtanj and the
village of Sesalac, Eastern Serbia. The main EO constituents of Lamiaceae plants were p-cymene
(24.4%), geraniol (63.4%) and germacrene D (21.5%) in Satureja kitaibelii, Thymus serpyllum and
Origanum vulgare ssp. vulgare, respectively. A. millefolium EO had multiple constituents with major
ones being camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-cineole (5.6%),
while the main EO constituents of A. clypeolata were 1,8-cineole (45.1%) and camphor (18.2%).
Antimicrobial testing of the EO showed that Staphylococcus aureus (Gram-positive) was more sensitive
to all of the tested EOs than Escherichia coli (Gram-negative). S. kitaibelii EO showed the highest
antimicrobial activity against both tested bacterial strains. This is the first study to characterize
the EO composition and antimicrobial activity of these five medicinal species from Eastern Serbia
in comparison with comprehensive literature data. The results can be utilized by the perfumery,
cosmetics, food and pharmaceutical industries, but also for healing purposes in self-medication.
PB  - MDPI
T2  - Molecules
T1  - Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia
VL  - 25
IS  - 22
SP  - 5482
DO  - 10.3390/molecules25225482
ER  - 

@article{
author = "Aćimović, Milica and Zorić, Miroslav and Zheljazkov, Valtcho and Pezo, Lato and Čabarkapa, Ivana and Stanković Jeremić, Jovana and Cvetković, Mirjana",
year = "2020",
abstract = "The objective of this study was to evaluate wild growing Satureja kitaibelii, Thymus serpyllum,
Origanum vulgare, Achillea millefolium and Achillea clypeolata with respect to their essential oil (EO)
content, composition and antimicrobial activity. The five species were collected at Mt. Rtanj and the
village of Sesalac, Eastern Serbia. The main EO constituents of Lamiaceae plants were p-cymene
(24.4%), geraniol (63.4%) and germacrene D (21.5%) in Satureja kitaibelii, Thymus serpyllum and
Origanum vulgare ssp. vulgare, respectively. A. millefolium EO had multiple constituents with major
ones being camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-cineole (5.6%),
while the main EO constituents of A. clypeolata were 1,8-cineole (45.1%) and camphor (18.2%).
Antimicrobial testing of the EO showed that Staphylococcus aureus (Gram-positive) was more sensitive
to all of the tested EOs than Escherichia coli (Gram-negative). S. kitaibelii EO showed the highest
antimicrobial activity against both tested bacterial strains. This is the first study to characterize
the EO composition and antimicrobial activity of these five medicinal species from Eastern Serbia
in comparison with comprehensive literature data. The results can be utilized by the perfumery,
cosmetics, food and pharmaceutical industries, but also for healing purposes in self-medication.",
publisher = "MDPI",
journal = "Molecules",
title = "Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia",
volume = "25",
number = "22",
pages = "5482",
doi = "10.3390/molecules25225482"
}

Aćimović, M., Zorić, M., Zheljazkov, V., Pezo, L., Čabarkapa, I., Stanković Jeremić, J.,& Cvetković, M.. (2020). Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia. in Molecules
MDPI., 25(22), 5482.
https://doi.org/10.3390/molecules25225482

Aćimović M, Zorić M, Zheljazkov V, Pezo L, Čabarkapa I, Stanković Jeremić J, Cvetković M. Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia. in Molecules. 2020;25(22):5482.
doi:10.3390/molecules25225482 .

Aćimović, Milica, Zorić, Miroslav, Zheljazkov, Valtcho, Pezo, Lato, Čabarkapa, Ivana, Stanković Jeremić, Jovana, Cvetković, Mirjana, "Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia" in Molecules, 25, no. 22 (2020):5482,
https://doi.org/10.3390/molecules25225482 . .