TY  - JOUR
AU  - Mileski, Ksenija S
AU  - Ciric, Ana D
AU  - Trifunović, Snežana
AU  - Ristic, Mihailo S
AU  - Soković, Marina
AU  - Matevski, Vlado S
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Marin, Petar D.
AU  - Dzamic, Ana M
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3130
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food & Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
IS  - 9
SP  - 4061
EP  - 4074
DO  - 10.1039/c6fo01018k
ER  - 

@article{
author = "Mileski, Ksenija S and Ciric, Ana D and Trifunović, Snežana and Ristic, Mihailo S and Soković, Marina and Matevski, Vlado S and Tešević, Vele and Jadranin, Milka and Marin, Petar D. and Dzamic, Ana M",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food & Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
number = "9",
pages = "4061-4074",
doi = "10.1039/c6fo01018k"
}

Mileski, K. S., Ciric, A. D., Trifunović, S., Ristic, M. S., Soković, M., Matevski, V. S., Tešević, V., Jadranin, M., Marin, P. D.,& Dzamic, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food & Function
Royal Soc Chemistry, Cambridge., 7(9), 4061-4074.
https://doi.org/10.1039/c6fo01018k

Mileski KS, Ciric AD, Trifunović S, Ristic MS, Soković M, Matevski VS, Tešević V, Jadranin M, Marin PD, Dzamic AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food & Function. 2016;7(9):4061-4074.
doi:10.1039/c6fo01018k .

Mileski, Ksenija S, Ciric, Ana D, Trifunović, Snežana, Ristic, Mihailo S, Soković, Marina, Matevski, Vlado S, Tešević, Vele, Jadranin, Milka, Marin, Petar D., Dzamic, Ana M, "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food & Function, 7, no. 9 (2016):4061-4074,
https://doi.org/10.1039/c6fo01018k . .

TY  - JOUR
AU  - Mileski, Ksenija S
AU  - Ciric, Ana D
AU  - Trifunović, Snežana
AU  - Ristic, Mihailo S
AU  - Soković, Marina
AU  - Matevski, Vlado S
AU  - Tešević, Vele
AU  - Jadranin, Milka
AU  - Marin, Petar D.
AU  - Dzamic, Ana M
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1923
AB  - GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food & Function
T1  - Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1
VL  - 7
IS  - 9
SP  - 4061
EP  - 4074
DO  - 10.1039/c6fo01018k
ER  - 

@article{
author = "Mileski, Ksenija S and Ciric, Ana D and Trifunović, Snežana and Ristic, Mihailo S and Soković, Marina and Matevski, Vlado S and Tešević, Vele and Jadranin, Milka and Marin, Petar D. and Dzamic, Ana M",
year = "2016",
abstract = "GC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food & Function",
title = "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1",
volume = "7",
number = "9",
pages = "4061-4074",
doi = "10.1039/c6fo01018k"
}

Mileski, K. S., Ciric, A. D., Trifunović, S., Ristic, M. S., Soković, M., Matevski, V. S., Tešević, V., Jadranin, M., Marin, P. D.,& Dzamic, A. M.. (2016). Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food & Function
Royal Soc Chemistry, Cambridge., 7(9), 4061-4074.
https://doi.org/10.1039/c6fo01018k

Mileski KS, Ciric AD, Trifunović S, Ristic MS, Soković M, Matevski VS, Tešević V, Jadranin M, Marin PD, Dzamic AM. Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1. in Food & Function. 2016;7(9):4061-4074.
doi:10.1039/c6fo01018k .

Mileski, Ksenija S, Ciric, Ana D, Trifunović, Snežana, Ristic, Mihailo S, Soković, Marina, Matevski, Vlado S, Tešević, Vele, Jadranin, Milka, Marin, Petar D., Dzamic, Ana M, "Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1" in Food & Function, 7, no. 9 (2016):4061-4074,
https://doi.org/10.1039/c6fo01018k . .

TY  - JOUR
AU  - Pljevljakusic, Dejan
AU  - Savikin, Katarina
AU  - Janković, Teodora
AU  - Zdunić, Gordana
AU  - Ristic, Mihailo
AU  - Gođevac, Dejan
AU  - Konic-Ristic, Aleksandra
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/867
AB  - Phytochemical analyses of the cultivated Sideritis raeseri subsp. raeseri in four different stages of flower development were performed. Traditionally used infusion and decoction were also prepared from aerial parts in full flowering stage, and analyses of active compounds and radical scavenging capacity were performed. The highest yield of the essential oil, obtained by hydrodistillation, was noticed in the full flowering phase (0.11%), with sesquiterpene bicyclogermacrene as the main constituent (42.5%). All examined extracts contained phenolic compounds and their amounts varied from 15.3 to 34.1 mg GAE/g DW. The amounts of total phenolics in infusion and decoction were similar (46.5 and 43.9 mg GAE/100 ml, respectively). LC-ESI-MS analyses of all samples allowed the characterisation of 22 phenolic compounds. Two dominant flavone glycosides, 4'-O-methylhypolaetin-7-O-[6"'-O-acetyl-beta-D-allopyranosyl (1 -> 2)-beta-D-glucopyranoside (17) and 4'-O-methylisoscutellarein-7-O-[6"'-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside (19) were quantified using HPLC. Moreover, the mineral content and the percent of transportation were investigated.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Chemical properties of the cultivated Sideritis raeseri Boiss. & Heldr. subsp raeseri
VL  - 124
IS  - 1
SP  - 226
EP  - 233
DO  - 10.1016/j.foodchem.2010.06.023
ER  - 

@article{
author = "Pljevljakusic, Dejan and Savikin, Katarina and Janković, Teodora and Zdunić, Gordana and Ristic, Mihailo and Gođevac, Dejan and Konic-Ristic, Aleksandra",
year = "2011",
abstract = "Phytochemical analyses of the cultivated Sideritis raeseri subsp. raeseri in four different stages of flower development were performed. Traditionally used infusion and decoction were also prepared from aerial parts in full flowering stage, and analyses of active compounds and radical scavenging capacity were performed. The highest yield of the essential oil, obtained by hydrodistillation, was noticed in the full flowering phase (0.11%), with sesquiterpene bicyclogermacrene as the main constituent (42.5%). All examined extracts contained phenolic compounds and their amounts varied from 15.3 to 34.1 mg GAE/g DW. The amounts of total phenolics in infusion and decoction were similar (46.5 and 43.9 mg GAE/100 ml, respectively). LC-ESI-MS analyses of all samples allowed the characterisation of 22 phenolic compounds. Two dominant flavone glycosides, 4'-O-methylhypolaetin-7-O-[6"'-O-acetyl-beta-D-allopyranosyl (1 -> 2)-beta-D-glucopyranoside (17) and 4'-O-methylisoscutellarein-7-O-[6"'-O-acetyl-beta-D-allopyranosyl-(1 -> 2)]-beta-D-glucopyranoside (19) were quantified using HPLC. Moreover, the mineral content and the percent of transportation were investigated.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Chemical properties of the cultivated Sideritis raeseri Boiss. & Heldr. subsp raeseri",
volume = "124",
number = "1",
pages = "226-233",
doi = "10.1016/j.foodchem.2010.06.023"
}

Pljevljakusic, D., Savikin, K., Janković, T., Zdunić, G., Ristic, M., Gođevac, D.,& Konic-Ristic, A.. (2011). Chemical properties of the cultivated Sideritis raeseri Boiss. & Heldr. subsp raeseri. in Food Chemistry
Elsevier Sci Ltd, Oxford., 124(1), 226-233.
https://doi.org/10.1016/j.foodchem.2010.06.023

Pljevljakusic D, Savikin K, Janković T, Zdunić G, Ristic M, Gođevac D, Konic-Ristic A. Chemical properties of the cultivated Sideritis raeseri Boiss. & Heldr. subsp raeseri. in Food Chemistry. 2011;124(1):226-233.
doi:10.1016/j.foodchem.2010.06.023 .

Pljevljakusic, Dejan, Savikin, Katarina, Janković, Teodora, Zdunić, Gordana, Ristic, Mihailo, Gođevac, Dejan, Konic-Ristic, Aleksandra, "Chemical properties of the cultivated Sideritis raeseri Boiss. & Heldr. subsp raeseri" in Food Chemistry, 124, no. 1 (2011):226-233,
https://doi.org/10.1016/j.foodchem.2010.06.023 . .