TY  - JOUR
AU  - Gligorijević, Nevenka
AU  - Todorović, Tamara
AU  - Radulović, Siniša
AU  - Sladić, Dušan
AU  - Filipović, N.
AU  - Gođevac, Dejan
AU  - Jeremić, D.
AU  - Anđelković, Katarina
PY  - 2009
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/596
AB  - New complexes of Pt(II) and Pd(II) with 2-quinolinecarboxaldehyde selenosemicarbazone were synthesized and characterized by elemental analysis, NMR and IR spectroscopy and molar conductivity measurements. The assumed geometry of Pt(II) and Pd(II) complexes was square planar where the ligand was tridentately coordinated via the quinoline and imine nitrogen atoms and the selenium atom. The cytotoxic activity of the new Pt(II) and Pd(II) compounds, as well as of some previously synthesized Cd(II), Zn(II) and Ni(II) complexes with the same or analogous ligand, was tested against a panel of three human cancer cell lines: human cervix carcinoma cells (HeLa), human melanoma cells (FemX) and breast cancer cells (MDA-361). All investigated compounds, except Pt(II) complex, possess a strong dose-dependent cytotoxic activity of the same order of magnitude as cisplatin (CDDP). The investigation of potential of these compounds to induce HeLa cell cycle perturbations was also evaluated.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux
T2  - European Journal of Medicinal Chemistry
T1  - Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones
VL  - 44
IS  - 4
SP  - 1623
EP  - 1629
DO  - 10.1016/j.ejmech.2008.07.033
ER  - 

@article{
author = "Gligorijević, Nevenka and Todorović, Tamara and Radulović, Siniša and Sladić, Dušan and Filipović, N. and Gođevac, Dejan and Jeremić, D. and Anđelković, Katarina",
year = "2009",
abstract = "New complexes of Pt(II) and Pd(II) with 2-quinolinecarboxaldehyde selenosemicarbazone were synthesized and characterized by elemental analysis, NMR and IR spectroscopy and molar conductivity measurements. The assumed geometry of Pt(II) and Pd(II) complexes was square planar where the ligand was tridentately coordinated via the quinoline and imine nitrogen atoms and the selenium atom. The cytotoxic activity of the new Pt(II) and Pd(II) compounds, as well as of some previously synthesized Cd(II), Zn(II) and Ni(II) complexes with the same or analogous ligand, was tested against a panel of three human cancer cell lines: human cervix carcinoma cells (HeLa), human melanoma cells (FemX) and breast cancer cells (MDA-361). All investigated compounds, except Pt(II) complex, possess a strong dose-dependent cytotoxic activity of the same order of magnitude as cisplatin (CDDP). The investigation of potential of these compounds to induce HeLa cell cycle perturbations was also evaluated.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux",
journal = "European Journal of Medicinal Chemistry",
title = "Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones",
volume = "44",
number = "4",
pages = "1623-1629",
doi = "10.1016/j.ejmech.2008.07.033"
}

Gligorijević, N., Todorović, T., Radulović, S., Sladić, D., Filipović, N., Gođevac, D., Jeremić, D.,& Anđelković, K.. (2009). Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux., 44(4), 1623-1629.
https://doi.org/10.1016/j.ejmech.2008.07.033

Gligorijević N, Todorović T, Radulović S, Sladić D, Filipović N, Gođevac D, Jeremić D, Anđelković K. Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones. in European Journal of Medicinal Chemistry. 2009;44(4):1623-1629.
doi:10.1016/j.ejmech.2008.07.033 .

Gligorijević, Nevenka, Todorović, Tamara, Radulović, Siniša, Sladić, Dušan, Filipović, N., Gođevac, Dejan, Jeremić, D., Anđelković, Katarina, "Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones" in European Journal of Medicinal Chemistry, 44, no. 4 (2009):1623-1629,
https://doi.org/10.1016/j.ejmech.2008.07.033 . .

TY  - CONF
AU  - Filipović, N.R.
AU  - Todorović, Tamara
AU  - Sladić, Dušan
AU  - Novaković, Irena
AU  - Jeremić, D. A.
AU  - Anđelković, Katarina
PY  - 2007
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/344
AB  - New complexes of Pt(II) with condensation derivatives of ethyl hydrazinoacetate and either 2-acetylpyridine or 2-quinolinecarboxaldehyde, and of Pd(II) with the condensation derivative of ethyl hydrazinoacetate and 2-quinolinecarboxaldehyde were synthesized and characterized by elemental analysis, IR, 1H- and 13C-NMR spectroscopy, and molar conductivity measurements. The complexes have a square planar geometry, ligands binding as bidentates in the neutral form, and the remaining two coordination sites being occupied by chloride ions. Biological activity of new complexes, and of previously synthesized Pd(II), Cd(II), Co(III) and Zn(II) complexes with this ligand type was evaluated by the brine shrimp test. All the complexes showed a moderate activity.
C3  - Materials Science Forum
T1  - Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands
VL  - 555
SP  - 423
EP  - 427
DO  - 10.4028/www.scientific.net/MSF.555.423
ER  - 

@conference{
author = "Filipović, N.R. and Todorović, Tamara and Sladić, Dušan and Novaković, Irena and Jeremić, D. A. and Anđelković, Katarina",
year = "2007",
abstract = "New complexes of Pt(II) with condensation derivatives of ethyl hydrazinoacetate and either 2-acetylpyridine or 2-quinolinecarboxaldehyde, and of Pd(II) with the condensation derivative of ethyl hydrazinoacetate and 2-quinolinecarboxaldehyde were synthesized and characterized by elemental analysis, IR, 1H- and 13C-NMR spectroscopy, and molar conductivity measurements. The complexes have a square planar geometry, ligands binding as bidentates in the neutral form, and the remaining two coordination sites being occupied by chloride ions. Biological activity of new complexes, and of previously synthesized Pd(II), Cd(II), Co(III) and Zn(II) complexes with this ligand type was evaluated by the brine shrimp test. All the complexes showed a moderate activity.",
journal = "Materials Science Forum",
title = "Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands",
volume = "555",
pages = "423-427",
doi = "10.4028/www.scientific.net/MSF.555.423"
}

Filipović, N.R., Todorović, T., Sladić, D., Novaković, I., Jeremić, D. A.,& Anđelković, K.. (2007). Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands. in Materials Science Forum, 555, 423-427.
https://doi.org/10.4028/www.scientific.net/MSF.555.423

Filipović N, Todorović T, Sladić D, Novaković I, Jeremić DA, Anđelković K. Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands. in Materials Science Forum. 2007;555:423-427.
doi:10.4028/www.scientific.net/MSF.555.423 .

Filipović, N.R., Todorović, Tamara, Sladić, Dušan, Novaković, Irena, Jeremić, D. A., Anđelković, Katarina, "Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands" in Materials Science Forum, 555 (2007):423-427,
https://doi.org/10.4028/www.scientific.net/MSF.555.423 . .

TY  - JOUR
AU  - Došen-Mićović, Ljiljana
AU  - Jeremić, D.
PY  - 1985
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4519
AB  - The conformational equilibrium has been measured for r-1,c-3-dichloro-t-5-methylcyclohexane(2) in six solvents from the 500 MHz and 400 MHz 1H NMR spectra. The room-temperature and low-temperature C1H couplings are used as well as the vicinal proton-proton coupling constants based on the MM2-calculated dihedral angles and the empirically generalized Karplus equation. The equilibrium exhibits a very weak solvent dependence; ΔGaa-ee varies from 1.22 kcal mol-1 in CDCl3 to 0.87 kcal mol-1 in DMSO-d6. The free energy difference, Δaa-ee II 0.90 kcal mol-1, in CD2Cl2 is determined by peak-area NMR measurements at -100°C. The reaction field theory is used to calculate the variation of Δaa-ee with solvent polarity. The calculated solvent shift δΔGaa-ee (CDCl3 to DMSO-d6) is -0.21 kcal mol-1, compared with -0.35 kcal mol-1 determined experimentally.
PB  - Elsevier
T2  - Journal of Molecular Structure
T1  - The solvent effect on the conformational equilibrium of 1,3-dichloro-5-methylcylclohexane
VL  - 131
IS  - 3-4
SP  - 261
EP  - 266
DO  - 10.1016/0022-2860(85)87027-7
ER  - 

@article{
author = "Došen-Mićović, Ljiljana and Jeremić, D.",
year = "1985",
abstract = "The conformational equilibrium has been measured for r-1,c-3-dichloro-t-5-methylcyclohexane(2) in six solvents from the 500 MHz and 400 MHz 1H NMR spectra. The room-temperature and low-temperature C1H couplings are used as well as the vicinal proton-proton coupling constants based on the MM2-calculated dihedral angles and the empirically generalized Karplus equation. The equilibrium exhibits a very weak solvent dependence; ΔGaa-ee varies from 1.22 kcal mol-1 in CDCl3 to 0.87 kcal mol-1 in DMSO-d6. The free energy difference, Δaa-ee II 0.90 kcal mol-1, in CD2Cl2 is determined by peak-area NMR measurements at -100°C. The reaction field theory is used to calculate the variation of Δaa-ee with solvent polarity. The calculated solvent shift δΔGaa-ee (CDCl3 to DMSO-d6) is -0.21 kcal mol-1, compared with -0.35 kcal mol-1 determined experimentally.",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "The solvent effect on the conformational equilibrium of 1,3-dichloro-5-methylcylclohexane",
volume = "131",
number = "3-4",
pages = "261-266",
doi = "10.1016/0022-2860(85)87027-7"
}

Došen-Mićović, L.,& Jeremić, D.. (1985). The solvent effect on the conformational equilibrium of 1,3-dichloro-5-methylcylclohexane. in Journal of Molecular Structure
Elsevier., 131(3-4), 261-266.
https://doi.org/10.1016/0022-2860(85)87027-7

Došen-Mićović L, Jeremić D. The solvent effect on the conformational equilibrium of 1,3-dichloro-5-methylcylclohexane. in Journal of Molecular Structure. 1985;131(3-4):261-266.
doi:10.1016/0022-2860(85)87027-7 .

Došen-Mićović, Ljiljana, Jeremić, D., "The solvent effect on the conformational equilibrium of 1,3-dichloro-5-methylcylclohexane" in Journal of Molecular Structure, 131, no. 3-4 (1985):261-266,
https://doi.org/10.1016/0022-2860(85)87027-7 . .