TY  - JOUR
AU  - Rajić, Jasmina R.
AU  - Đorđević, Sofija M.
AU  - Tešević, Vele
AU  - Živković, Marijana
AU  - Đorđević, Neda O.
AU  - Paunović, Dragana
AU  - Nedović, Viktor A.
AU  - Petrović, Tanja S.
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2274
AB  - In this study, the polyphenol profile and antioxidant activity of the hydro-ethanolic extract of the fennel fruit were examined in order to investigate the possibility of its application as a potential functional food additive. Total phenols were analyzed by the method of Folin-Ciocalteu, while total flavonoids were determined by the aluminum chloride colorimetric method. The separation and quantification of phenolic compounds were performed by LC-MS/MS analysis, using a multiple reaction monitoring (MRM) mode. The antioxidant capacity was determined by FRAP and DPPH assays. The high values of total phenolics and flavonoids were found, as well as high antioxidant activity which amounted to 9023.33 ± 38.19 µmol Fe(II)/l and 3.73 ± 0.04 mmol TE/l, tested by FRAP and DPPH assays, respectively. Among the identified phenolic compounds, p-hydroxybenzoic and chlorogenic acids were detected as predominant. The obtained results indicated that the hydro-ethanolic extract of the fennel fruit can be used in food industry as a potential natural antioxidant.
AB  - U ovom radu određivan je sadržaj polifenola i antioksidativna aktivnost vodeno-etanolnog ekstrakta morača, sa ciljem ispitivanja mogućnosti njegove primene kao potencijalnog funkcionalnog aditiva. Ukupni fenoli su analizirani metodom po Folin-Ciocalteu, dok je ukupan sadržaj flavonoida određen kolorimetrijskom metodom primenom aluminijum hlorida. Razdvajanje i kvantifikacija fenolnih jedinjenja postignuti su upotrebom LC-MS/MS metode u režimu koji omogućava istovremeno praćenje više jonskih prelaza. Antioksidativni kapacitet je određivan primenom testova FRAP i DPPH. U testiranom ekstraktu dobijene su visoke vrednosti za ukupne fenole i flavonoide, a dobijena je i visoka vrednost antioksidativne aktivnosti, koja je iznosila 9023.33 ± 38,19 mmol Fe(II)/l i 3,73 ± 0,04 mmol TE/l, računato primenom testa FRAP odnosno testa DPPH. Među fenolnim jedinjenjima, phidroksibenzoeva i hlorogena kiselina su pronađene kao dominantne. Dobijeni rezultati ukazuju na to da se ekstrakt morača može primenjivati u prehrambenoj industriji kao potencijalni prirodni antioksidans.
PB  - Poljoprivredni fakultet, Beograd
T2  - Journal of Agricultural Sciences
T1  - The extract of fennel fruit as a potential natural additive in food industry
T1  - Ekstrakt ploda morača kao potencijalni prirodni aditiv u prehrambenoj industriji
VL  - 63
IS  - 2
SP  - 205
EP  - 215
DO  - 10.2298/JAS1802205R
ER  - 

@article{
author = "Rajić, Jasmina R. and Đorđević, Sofija M. and Tešević, Vele and Živković, Marijana and Đorđević, Neda O. and Paunović, Dragana and Nedović, Viktor A. and Petrović, Tanja S.",
year = "2018",
abstract = "In this study, the polyphenol profile and antioxidant activity of the hydro-ethanolic extract of the fennel fruit were examined in order to investigate the possibility of its application as a potential functional food additive. Total phenols were analyzed by the method of Folin-Ciocalteu, while total flavonoids were determined by the aluminum chloride colorimetric method. The separation and quantification of phenolic compounds were performed by LC-MS/MS analysis, using a multiple reaction monitoring (MRM) mode. The antioxidant capacity was determined by FRAP and DPPH assays. The high values of total phenolics and flavonoids were found, as well as high antioxidant activity which amounted to 9023.33 ± 38.19 µmol Fe(II)/l and 3.73 ± 0.04 mmol TE/l, tested by FRAP and DPPH assays, respectively. Among the identified phenolic compounds, p-hydroxybenzoic and chlorogenic acids were detected as predominant. The obtained results indicated that the hydro-ethanolic extract of the fennel fruit can be used in food industry as a potential natural antioxidant., U ovom radu određivan je sadržaj polifenola i antioksidativna aktivnost vodeno-etanolnog ekstrakta morača, sa ciljem ispitivanja mogućnosti njegove primene kao potencijalnog funkcionalnog aditiva. Ukupni fenoli su analizirani metodom po Folin-Ciocalteu, dok je ukupan sadržaj flavonoida određen kolorimetrijskom metodom primenom aluminijum hlorida. Razdvajanje i kvantifikacija fenolnih jedinjenja postignuti su upotrebom LC-MS/MS metode u režimu koji omogućava istovremeno praćenje više jonskih prelaza. Antioksidativni kapacitet je određivan primenom testova FRAP i DPPH. U testiranom ekstraktu dobijene su visoke vrednosti za ukupne fenole i flavonoide, a dobijena je i visoka vrednost antioksidativne aktivnosti, koja je iznosila 9023.33 ± 38,19 mmol Fe(II)/l i 3,73 ± 0,04 mmol TE/l, računato primenom testa FRAP odnosno testa DPPH. Među fenolnim jedinjenjima, phidroksibenzoeva i hlorogena kiselina su pronađene kao dominantne. Dobijeni rezultati ukazuju na to da se ekstrakt morača može primenjivati u prehrambenoj industriji kao potencijalni prirodni antioksidans.",
publisher = "Poljoprivredni fakultet, Beograd",
journal = "Journal of Agricultural Sciences",
title = "The extract of fennel fruit as a potential natural additive in food industry, Ekstrakt ploda morača kao potencijalni prirodni aditiv u prehrambenoj industriji",
volume = "63",
number = "2",
pages = "205-215",
doi = "10.2298/JAS1802205R"
}

Rajić, J. R., Đorđević, S. M., Tešević, V., Živković, M., Đorđević, N. O., Paunović, D., Nedović, V. A.,& Petrović, T. S.. (2018). The extract of fennel fruit as a potential natural additive in food industry. in Journal of Agricultural Sciences
Poljoprivredni fakultet, Beograd., 63(2), 205-215.
https://doi.org/10.2298/JAS1802205R

Rajić JR, Đorđević SM, Tešević V, Živković M, Đorđević NO, Paunović D, Nedović VA, Petrović TS. The extract of fennel fruit as a potential natural additive in food industry. in Journal of Agricultural Sciences. 2018;63(2):205-215.
doi:10.2298/JAS1802205R .

Rajić, Jasmina R., Đorđević, Sofija M., Tešević, Vele, Živković, Marijana, Đorđević, Neda O., Paunović, Dragana, Nedović, Viktor A., Petrović, Tanja S., "The extract of fennel fruit as a potential natural additive in food industry" in Journal of Agricultural Sciences, 63, no. 2 (2018):205-215,
https://doi.org/10.2298/JAS1802205R . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Todorović, Nevena
AU  - Novaković, Irena
AU  - Pezo, Lato
AU  - Pejin, Boris
AU  - Maras, Vesna
AU  - Tešević, Vele
AU  - Pajovic, Snezana B.
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2485
AB  - Screens of antioxidant activity (AA) of various natural products have been a focus of the research community worldwide. This work aimed to differentiate selected samples of Merlot wines originated from Montenegro, with regard to phenolic profile and antioxidant capacity studied by survival rate, total sulfhydryl groups and activities of glutathione peroxidase (GPx), glutathione reductase and catalase in H2O2-stressed Saccharomyces cerevisiae cells. In this study, DPPH assay was also performed. Higher total phenolic content leads to an enhanced AA under both conditions. The same trend was observed for catechin and gallic acid, the most abundant phenolics in the examined wine samples. Finally, the findings of an Artificial Neural Network (ANN) model were in a good agreement (r(2) = 0.978) with the experimental data. All tested samples exhibited a protective effect in H2O2-stressed yeast cells. Pre-treatment with examined wines increased survival in H2O2-stressed cells and shifted antioxidative defense towards GPx-mediated defense. Finally, sensitivity analysis of obtained ANN model highlights the complexity of the impact that variations in the concentrations of specific phenolic components have on the antioxidant defense system.
PB  - MDPI
T2  - Molecules
T1  - Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine
VL  - 23
IS  - 8
DO  - 10.3390/molecules23081971
ER  - 

@article{
author = "Đorđević, Neda O. and Todorović, Nevena and Novaković, Irena and Pezo, Lato and Pejin, Boris and Maras, Vesna and Tešević, Vele and Pajovic, Snezana B.",
year = "2018",
abstract = "Screens of antioxidant activity (AA) of various natural products have been a focus of the research community worldwide. This work aimed to differentiate selected samples of Merlot wines originated from Montenegro, with regard to phenolic profile and antioxidant capacity studied by survival rate, total sulfhydryl groups and activities of glutathione peroxidase (GPx), glutathione reductase and catalase in H2O2-stressed Saccharomyces cerevisiae cells. In this study, DPPH assay was also performed. Higher total phenolic content leads to an enhanced AA under both conditions. The same trend was observed for catechin and gallic acid, the most abundant phenolics in the examined wine samples. Finally, the findings of an Artificial Neural Network (ANN) model were in a good agreement (r(2) = 0.978) with the experimental data. All tested samples exhibited a protective effect in H2O2-stressed yeast cells. Pre-treatment with examined wines increased survival in H2O2-stressed cells and shifted antioxidative defense towards GPx-mediated defense. Finally, sensitivity analysis of obtained ANN model highlights the complexity of the impact that variations in the concentrations of specific phenolic components have on the antioxidant defense system.",
publisher = "MDPI",
journal = "Molecules",
title = "Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine",
volume = "23",
number = "8",
doi = "10.3390/molecules23081971"
}

Đorđević, N. O., Todorović, N., Novaković, I., Pezo, L., Pejin, B., Maras, V., Tešević, V.,& Pajovic, S. B.. (2018). Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine. in Molecules
MDPI., 23(8).
https://doi.org/10.3390/molecules23081971

Đorđević NO, Todorović N, Novaković I, Pezo L, Pejin B, Maras V, Tešević V, Pajovic SB. Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine. in Molecules. 2018;23(8).
doi:10.3390/molecules23081971 .

Đorđević, Neda O., Todorović, Nevena, Novaković, Irena, Pezo, Lato, Pejin, Boris, Maras, Vesna, Tešević, Vele, Pajovic, Snezana B., "Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine" in Molecules, 23, no. 8 (2018),
https://doi.org/10.3390/molecules23081971 . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2456
AB  - The overall aim of this paper was to compare the multielement composition and antioxidant capacity of two Montenegrin Merlot wines obtained from specific vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011. Elemental composition was analysed using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Additionally, antioxidant capacity was assessed by cyclic voltammetry. VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, all three wines are good source of essential elements and products with a significant antioxidant activity and specific geographical origin.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro
VL  - 32
IS  - 3
SP  - 247
EP  - 251
DO  - 10.1080/14786419.2017.1347171
ER  - 

@article{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav and Stanković, Dalibor and Mutić, Jelena and Pajovic, Snezana B. and Tešević, Vele",
year = "2018",
abstract = "The overall aim of this paper was to compare the multielement composition and antioxidant capacity of two Montenegrin Merlot wines obtained from specific vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011. Elemental composition was analysed using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Additionally, antioxidant capacity was assessed by cyclic voltammetry. VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, all three wines are good source of essential elements and products with a significant antioxidant activity and specific geographical origin.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro",
volume = "32",
number = "3",
pages = "247-251",
doi = "10.1080/14786419.2017.1347171"
}

Đorđević, N. O., Pejin, B., Novaković, M., Stanković, D., Mutić, J., Pajovic, S. B.,& Tešević, V.. (2018). Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 32(3), 247-251.
https://doi.org/10.1080/14786419.2017.1347171

Đorđević NO, Pejin B, Novaković M, Stanković D, Mutić J, Pajovic SB, Tešević V. Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro. in Natural Product Research. 2018;32(3):247-251.
doi:10.1080/14786419.2017.1347171 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav, Stanković, Dalibor, Mutić, Jelena, Pajovic, Snezana B., Tešević, Vele, "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro" in Natural Product Research, 32, no. 3 (2018):247-251,
https://doi.org/10.1080/14786419.2017.1347171 . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Novaković, Miroslav
AU  - Pejin, Boris
AU  - Živković, Marijana
AU  - Savic, A.
AU  - Mutić, Jelena
AU  - Tešević, Vele
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2474
AB  - This study aimed to describe quality and potential health benefits of three Vranac wines obtained from new grape clones (CI, CII and CIII) recently developed and recognised. In this aim, their phenolic profiles, anti-2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical activities along with metal compositions were analyzed. Compared with the commercial one, CII and CIII Vranac wines were found to contain both higher contents of total phenolics, flavonoids and monomeric anthocyanins as well as anti-DPPH radical activities. The most abundant phenolics were gallic acid (8.88-16.36 mg/L), catechin (12.42-24.35 mg/L) and epicatechin (4.30-7.79 mg/L). Finally, the metal content of all the analyzed samples was within the toxicological safety limits. Taken all together, Montenegrin Vranac wines represent a rich source of both phenolics and minerals exhibiting promising antioxidant potential. CII and CIII wines can be considered for commercialising due to their high amounts of gallic acid, catechin and epicatechin, significant K/Na ratios and favourable contents of essential metals making them products with health added values.
PB  - Elsevier
T2  - Scientia Horticulturae
T1  - An insight into chemical composition and biological activity of Montenegrin Vranac red wine
VL  - 230
SP  - 142
EP  - 148
DO  - 10.1016/j.scienta.2017.11.033
ER  - 

@article{
author = "Đorđević, Neda O. and Novaković, Miroslav and Pejin, Boris and Živković, Marijana and Savic, A. and Mutić, Jelena and Tešević, Vele",
year = "2018",
abstract = "This study aimed to describe quality and potential health benefits of three Vranac wines obtained from new grape clones (CI, CII and CIII) recently developed and recognised. In this aim, their phenolic profiles, anti-2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical activities along with metal compositions were analyzed. Compared with the commercial one, CII and CIII Vranac wines were found to contain both higher contents of total phenolics, flavonoids and monomeric anthocyanins as well as anti-DPPH radical activities. The most abundant phenolics were gallic acid (8.88-16.36 mg/L), catechin (12.42-24.35 mg/L) and epicatechin (4.30-7.79 mg/L). Finally, the metal content of all the analyzed samples was within the toxicological safety limits. Taken all together, Montenegrin Vranac wines represent a rich source of both phenolics and minerals exhibiting promising antioxidant potential. CII and CIII wines can be considered for commercialising due to their high amounts of gallic acid, catechin and epicatechin, significant K/Na ratios and favourable contents of essential metals making them products with health added values.",
publisher = "Elsevier",
journal = "Scientia Horticulturae",
title = "An insight into chemical composition and biological activity of Montenegrin Vranac red wine",
volume = "230",
pages = "142-148",
doi = "10.1016/j.scienta.2017.11.033"
}

Đorđević, N. O., Novaković, M., Pejin, B., Živković, M., Savic, A., Mutić, J.,& Tešević, V.. (2018). An insight into chemical composition and biological activity of Montenegrin Vranac red wine. in Scientia Horticulturae
Elsevier., 230, 142-148.
https://doi.org/10.1016/j.scienta.2017.11.033

Đorđević NO, Novaković M, Pejin B, Živković M, Savic A, Mutić J, Tešević V. An insight into chemical composition and biological activity of Montenegrin Vranac red wine. in Scientia Horticulturae. 2018;230:142-148.
doi:10.1016/j.scienta.2017.11.033 .

Đorđević, Neda O., Novaković, Miroslav, Pejin, Boris, Živković, Marijana, Savic, A., Mutić, Jelena, Tešević, Vele, "An insight into chemical composition and biological activity of Montenegrin Vranac red wine" in Scientia Horticulturae, 230 (2018):142-148,
https://doi.org/10.1016/j.scienta.2017.11.033 . .

TY  - DATA
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4468
AB  - Experimental details: Standards and solvents; Wine samples; Multielement analysis; Cyclic voltammetric determination of antioxidant capacity. Additional references. Supplementary Figure: Cyclic voltammograms obtained for the analysed wine samples during 2010 (a) and 2011 (b) vintages. Table S1. The contents of major and trace elements in analysed wine samples determined by ICP-OES or ICP-MS. Table S2. The content of ultratrace elements in analysed wine samples determined by ICP-MS. Table S3. Antioxidant potency composite index (ACI) of the selected wine samples determined 9 by cyclic voltammetry and scaled to relative percentages.
PB  - Taylor & Francis
T2  - Natural Product Research
T1  - Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro"
DO  - 10.6084/m9.figshare.5182369
ER  - 

@misc{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav and Stanković, Dalibor and Mutić, Jelena and Pajovic, Snezana B. and Tešević, Vele",
year = "2018",
abstract = "Experimental details: Standards and solvents; Wine samples; Multielement analysis; Cyclic voltammetric determination of antioxidant capacity. Additional references. Supplementary Figure: Cyclic voltammograms obtained for the analysed wine samples during 2010 (a) and 2011 (b) vintages. Table S1. The contents of major and trace elements in analysed wine samples determined by ICP-OES or ICP-MS. Table S2. The content of ultratrace elements in analysed wine samples determined by ICP-MS. Table S3. Antioxidant potency composite index (ACI) of the selected wine samples determined 9 by cyclic voltammetry and scaled to relative percentages.",
publisher = "Taylor & Francis",
journal = "Natural Product Research",
title = "Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro"",
doi = "10.6084/m9.figshare.5182369"
}

Đorđević, N. O., Pejin, B., Novaković, M., Stanković, D., Mutić, J., Pajovic, S. B.,& Tešević, V.. (2018). Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro". in Natural Product Research
Taylor & Francis..
https://doi.org/10.6084/m9.figshare.5182369

Đorđević NO, Pejin B, Novaković M, Stanković D, Mutić J, Pajovic SB, Tešević V. Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro". in Natural Product Research. 2018;.
doi:10.6084/m9.figshare.5182369 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav, Stanković, Dalibor, Mutić, Jelena, Pajovic, Snezana B., Tešević, Vele, "Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro"" in Natural Product Research (2018),
https://doi.org/10.6084/m9.figshare.5182369 . .

TY  - JOUR
AU  - Nikolić, Jasna
AU  - Nešić, Andrijana
AU  - Čavić, Milena
AU  - Đorđević, Neda O.
AU  - Anđelković, Uroš
AU  - Atanasković-Marković, Marina
AU  - Drakulić, Branko
AU  - Gavrović-Jankulović, Marija
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2058
AB  - Background: Protein oxidation can occur as a consequence of lipid peroxidation during food processing. The aim of this work was to explore the effect of malondialdehyde (MDA) modification of ovalbumin (OVA) on its interaction with T84 intestinal cells. Methods: Molecular dynamics simulation was employed for the prediction of MDA modification in the OVA, while introduced structural changes were evaluated by measurement of carbonyl group content, fluorescence spectra, MS/MS analysis, and IgE reactivity. Effects of MDA modified OVA on T84 epithelial cells were analyzed by gene expression for pro-inflammatory cytokines and protein secretion. Results: Out of 9 predicted, five modified Lys residues were confirmed by MS/MS analysis: (51)TQINKVVR(58), (85)DILNQITKPNDVYSFSLASR(104), (111)YPILPEYLQCVKELYR(126), (187)AFKDEDTQAMPFR(99), (KIKVYLPR284)-K-277, and (IKVYLPR284)-I-278. The introduced MDA modifications influenced profile of IgE reactivity to OVA. Treatment of T84 epithelial cells with OVA and OVA modified with 1 mM MDA, induced up-regulation of pro-inflammatory cytokines (IL-1 beta,IL-25, IL-33, TSLP and TNF alpha), while OVA modification with 10 mM MDA induced down regulation of the cytokine expression profile, except for IL-1 beta. OVA and OVA modified with 1 mM MDA induced secretion of epithelial cells specific cytokine IL-33. Conclusions: This finding indicated that OVA and its MDA modified form have the potential to trigger the innate immunity by inducing up-regulation and secretion of pro-allergenic IL-33 in T84 intestinal epithelial cells. General significance: Interactions of ovalbumin and its MDA modified form with intestinal epithelial cells can induce a specific immunological priming necessary for the downstream activation of innate immunity.
PB  - Elsevier
T2  - Biochimica et Biophysica Acta-General Subjects
T1  - Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells
VL  - 1861
IS  - 2
SP  - 126
EP  - 134
DO  - 10.1016/j.bbagen.2016.11.021
ER  - 

@article{
author = "Nikolić, Jasna and Nešić, Andrijana and Čavić, Milena and Đorđević, Neda O. and Anđelković, Uroš and Atanasković-Marković, Marina and Drakulić, Branko and Gavrović-Jankulović, Marija",
year = "2017",
abstract = "Background: Protein oxidation can occur as a consequence of lipid peroxidation during food processing. The aim of this work was to explore the effect of malondialdehyde (MDA) modification of ovalbumin (OVA) on its interaction with T84 intestinal cells. Methods: Molecular dynamics simulation was employed for the prediction of MDA modification in the OVA, while introduced structural changes were evaluated by measurement of carbonyl group content, fluorescence spectra, MS/MS analysis, and IgE reactivity. Effects of MDA modified OVA on T84 epithelial cells were analyzed by gene expression for pro-inflammatory cytokines and protein secretion. Results: Out of 9 predicted, five modified Lys residues were confirmed by MS/MS analysis: (51)TQINKVVR(58), (85)DILNQITKPNDVYSFSLASR(104), (111)YPILPEYLQCVKELYR(126), (187)AFKDEDTQAMPFR(99), (KIKVYLPR284)-K-277, and (IKVYLPR284)-I-278. The introduced MDA modifications influenced profile of IgE reactivity to OVA. Treatment of T84 epithelial cells with OVA and OVA modified with 1 mM MDA, induced up-regulation of pro-inflammatory cytokines (IL-1 beta,IL-25, IL-33, TSLP and TNF alpha), while OVA modification with 10 mM MDA induced down regulation of the cytokine expression profile, except for IL-1 beta. OVA and OVA modified with 1 mM MDA induced secretion of epithelial cells specific cytokine IL-33. Conclusions: This finding indicated that OVA and its MDA modified form have the potential to trigger the innate immunity by inducing up-regulation and secretion of pro-allergenic IL-33 in T84 intestinal epithelial cells. General significance: Interactions of ovalbumin and its MDA modified form with intestinal epithelial cells can induce a specific immunological priming necessary for the downstream activation of innate immunity.",
publisher = "Elsevier",
journal = "Biochimica et Biophysica Acta-General Subjects",
title = "Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells",
volume = "1861",
number = "2",
pages = "126-134",
doi = "10.1016/j.bbagen.2016.11.021"
}

Nikolić, J., Nešić, A., Čavić, M., Đorđević, N. O., Anđelković, U., Atanasković-Marković, M., Drakulić, B.,& Gavrović-Jankulović, M.. (2017). Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells. in Biochimica et Biophysica Acta-General Subjects
Elsevier., 1861(2), 126-134.
https://doi.org/10.1016/j.bbagen.2016.11.021

Nikolić J, Nešić A, Čavić M, Đorđević NO, Anđelković U, Atanasković-Marković M, Drakulić B, Gavrović-Jankulović M. Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells. in Biochimica et Biophysica Acta-General Subjects. 2017;1861(2):126-134.
doi:10.1016/j.bbagen.2016.11.021 .

Nikolić, Jasna, Nešić, Andrijana, Čavić, Milena, Đorđević, Neda O., Anđelković, Uroš, Atanasković-Marković, Marina, Drakulić, Branko, Gavrović-Jankulović, Marija, "Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells" in Biochimica et Biophysica Acta-General Subjects, 1861, no. 2 (2017):126-134,
https://doi.org/10.1016/j.bbagen.2016.11.021 . .

TY  - JOUR
AU  - Nikolić, Jasna
AU  - Nešić, Andrijana
AU  - Čavić, Milena
AU  - Đorđević, Neda O.
AU  - Anđelković, Uroš
AU  - Atanasković-Marković, Marina
AU  - Drakulić, Branko
AU  - Gavrović-Jankulović, Marija
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3042
AB  - Background: Protein oxidation can occur as a consequence of lipid peroxidation during food processing. The aim of this work was to explore the effect of malondialdehyde (MDA) modification of ovalbumin (OVA) on its interaction with T84 intestinal cells. Methods: Molecular dynamics simulation was employed for the prediction of MDA modification in the OVA, while introduced structural changes were evaluated by measurement of carbonyl group content, fluorescence spectra, MS/MS analysis, and IgE reactivity. Effects of MDA modified OVA on T84 epithelial cells were analyzed by gene expression for pro-inflammatory cytokines and protein secretion. Results: Out of 9 predicted, five modified Lys residues were confirmed by MS/MS analysis: (51)TQINKVVR(58), (85)DILNQITKPNDVYSFSLASR(104), (111)YPILPEYLQCVKELYR(126), (187)AFKDEDTQAMPFR(99), (KIKVYLPR284)-K-277, and (IKVYLPR284)-I-278. The introduced MDA modifications influenced profile of IgE reactivity to OVA. Treatment of T84 epithelial cells with OVA and OVA modified with 1 mM MDA, induced up-regulation of pro-inflammatory cytokines (IL-1 beta,IL-25, IL-33, TSLP and TNF alpha), while OVA modification with 10 mM MDA induced down regulation of the cytokine expression profile, except for IL-1 beta. OVA and OVA modified with 1 mM MDA induced secretion of epithelial cells specific cytokine IL-33. Conclusions: This finding indicated that OVA and its MDA modified form have the potential to trigger the innate immunity by inducing up-regulation and secretion of pro-allergenic IL-33 in T84 intestinal epithelial cells. General significance: Interactions of ovalbumin and its MDA modified form with intestinal epithelial cells can induce a specific immunological priming necessary for the downstream activation of innate immunity.
PB  - Elsevier
T2  - Biochimica et Biophysica Acta-General Subjects
T1  - Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells
VL  - 1861
IS  - 2
SP  - 126
EP  - 134
DO  - 10.1016/j.bbagen.2016.11.021
ER  - 

@article{
author = "Nikolić, Jasna and Nešić, Andrijana and Čavić, Milena and Đorđević, Neda O. and Anđelković, Uroš and Atanasković-Marković, Marina and Drakulić, Branko and Gavrović-Jankulović, Marija",
year = "2017",
abstract = "Background: Protein oxidation can occur as a consequence of lipid peroxidation during food processing. The aim of this work was to explore the effect of malondialdehyde (MDA) modification of ovalbumin (OVA) on its interaction with T84 intestinal cells. Methods: Molecular dynamics simulation was employed for the prediction of MDA modification in the OVA, while introduced structural changes were evaluated by measurement of carbonyl group content, fluorescence spectra, MS/MS analysis, and IgE reactivity. Effects of MDA modified OVA on T84 epithelial cells were analyzed by gene expression for pro-inflammatory cytokines and protein secretion. Results: Out of 9 predicted, five modified Lys residues were confirmed by MS/MS analysis: (51)TQINKVVR(58), (85)DILNQITKPNDVYSFSLASR(104), (111)YPILPEYLQCVKELYR(126), (187)AFKDEDTQAMPFR(99), (KIKVYLPR284)-K-277, and (IKVYLPR284)-I-278. The introduced MDA modifications influenced profile of IgE reactivity to OVA. Treatment of T84 epithelial cells with OVA and OVA modified with 1 mM MDA, induced up-regulation of pro-inflammatory cytokines (IL-1 beta,IL-25, IL-33, TSLP and TNF alpha), while OVA modification with 10 mM MDA induced down regulation of the cytokine expression profile, except for IL-1 beta. OVA and OVA modified with 1 mM MDA induced secretion of epithelial cells specific cytokine IL-33. Conclusions: This finding indicated that OVA and its MDA modified form have the potential to trigger the innate immunity by inducing up-regulation and secretion of pro-allergenic IL-33 in T84 intestinal epithelial cells. General significance: Interactions of ovalbumin and its MDA modified form with intestinal epithelial cells can induce a specific immunological priming necessary for the downstream activation of innate immunity.",
publisher = "Elsevier",
journal = "Biochimica et Biophysica Acta-General Subjects",
title = "Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells",
volume = "1861",
number = "2",
pages = "126-134",
doi = "10.1016/j.bbagen.2016.11.021"
}

Nikolić, J., Nešić, A., Čavić, M., Đorđević, N. O., Anđelković, U., Atanasković-Marković, M., Drakulić, B.,& Gavrović-Jankulović, M.. (2017). Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells. in Biochimica et Biophysica Acta-General Subjects
Elsevier., 1861(2), 126-134.
https://doi.org/10.1016/j.bbagen.2016.11.021

Nikolić J, Nešić A, Čavić M, Đorđević NO, Anđelković U, Atanasković-Marković M, Drakulić B, Gavrović-Jankulović M. Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells. in Biochimica et Biophysica Acta-General Subjects. 2017;1861(2):126-134.
doi:10.1016/j.bbagen.2016.11.021 .

Nikolić, Jasna, Nešić, Andrijana, Čavić, Milena, Đorđević, Neda O., Anđelković, Uroš, Atanasković-Marković, Marina, Drakulić, Branko, Gavrović-Jankulović, Marija, "Effect of malondialdehyde on the ovalbumin structure and its interactions with T84 epithelial cells" in Biochimica et Biophysica Acta-General Subjects, 1861, no. 2 (2017):126-134,
https://doi.org/10.1016/j.bbagen.2016.11.021 . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2154
AB  - The overall aim was to compare the quality of two Montenegrin Merlot wines obtained from new vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011, due to preliminary screening of the potential of novel Merlot vine clones for the wine industry. The content of phenolic compounds was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS). Elemental composition was analysed using inductively coupled plasma optical emission spectrometery (ICP-OES) and inductively coupled plasma mass spectrometery (ICP-MS)]. Additionaly, antioxidant capacity was assessed by cyclic voltammetry. Compared with the commercial one, both wine clones contained higher percent of major phenolic compounds (namely, gallic acid and catechin) with top values recorded for VCR1 both in 2010 (30.46 +/- 0.42 mg/1) and 2011 (28.12 +/- 0.29 mg/1). The same wines were enriched with epicatechin, resveratrol, myricetin and quercetin. Furthermore, VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, both new Montenegrin Merlot wines represent good candidates for the commercialised wines with an indication of geographical origin.
PB  - Elsevier
T2  - Scientia Horticulturae
T1  - Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro
VL  - 225
SP  - 505
EP  - 511
DO  - 10.1016/j.scienta.2017.07.045
ER  - 

@article{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav and Stanković, Dalibor and Mutić, Jelena and Pajovic, Snezana B. and Tešević, Vele",
year = "2017",
abstract = "The overall aim was to compare the quality of two Montenegrin Merlot wines obtained from new vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011, due to preliminary screening of the potential of novel Merlot vine clones for the wine industry. The content of phenolic compounds was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS). Elemental composition was analysed using inductively coupled plasma optical emission spectrometery (ICP-OES) and inductively coupled plasma mass spectrometery (ICP-MS)]. Additionaly, antioxidant capacity was assessed by cyclic voltammetry. Compared with the commercial one, both wine clones contained higher percent of major phenolic compounds (namely, gallic acid and catechin) with top values recorded for VCR1 both in 2010 (30.46 +/- 0.42 mg/1) and 2011 (28.12 +/- 0.29 mg/1). The same wines were enriched with epicatechin, resveratrol, myricetin and quercetin. Furthermore, VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, both new Montenegrin Merlot wines represent good candidates for the commercialised wines with an indication of geographical origin.",
publisher = "Elsevier",
journal = "Scientia Horticulturae",
title = "Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro",
volume = "225",
pages = "505-511",
doi = "10.1016/j.scienta.2017.07.045"
}

Đorđević, N. O., Pejin, B., Novaković, M., Stanković, D., Mutić, J., Pajovic, S. B.,& Tešević, V.. (2017). Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro. in Scientia Horticulturae
Elsevier., 225, 505-511.
https://doi.org/10.1016/j.scienta.2017.07.045

Đorđević NO, Pejin B, Novaković M, Stanković D, Mutić J, Pajovic SB, Tešević V. Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro. in Scientia Horticulturae. 2017;225:505-511.
doi:10.1016/j.scienta.2017.07.045 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav, Stanković, Dalibor, Mutić, Jelena, Pajovic, Snezana B., Tešević, Vele, "Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro" in Scientia Horticulturae, 225 (2017):505-511,
https://doi.org/10.1016/j.scienta.2017.07.045 . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Novaković, Miroslav
AU  - Pejin, Boris
AU  - Mutić, Jelena
AU  - Vajs, Vlatka
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2252
AB  - Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010-2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R=0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products. [GRAPHICS] .
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Comparative analytical study of the selected wine varieties grown in Montenegro
VL  - 31
IS  - 15
SP  - 1825
EP  - 1830
DO  - 10.1080/14786419.2017.1289209
ER  - 

@article{
author = "Đorđević, Neda O. and Novaković, Miroslav and Pejin, Boris and Mutić, Jelena and Vajs, Vlatka and Pajovic, Snezana B. and Tešević, Vele",
year = "2017",
abstract = "Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010-2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R=0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products. [GRAPHICS] .",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Comparative analytical study of the selected wine varieties grown in Montenegro",
volume = "31",
number = "15",
pages = "1825-1830",
doi = "10.1080/14786419.2017.1289209"
}

Đorđević, N. O., Novaković, M., Pejin, B., Mutić, J., Vajs, V., Pajovic, S. B.,& Tešević, V.. (2017). Comparative analytical study of the selected wine varieties grown in Montenegro. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 31(15), 1825-1830.
https://doi.org/10.1080/14786419.2017.1289209

Đorđević NO, Novaković M, Pejin B, Mutić J, Vajs V, Pajovic SB, Tešević V. Comparative analytical study of the selected wine varieties grown in Montenegro. in Natural Product Research. 2017;31(15):1825-1830.
doi:10.1080/14786419.2017.1289209 .

Đorđević, Neda O., Novaković, Miroslav, Pejin, Boris, Mutić, Jelena, Vajs, Vlatka, Pajovic, Snezana B., Tešević, Vele, "Comparative analytical study of the selected wine varieties grown in Montenegro" in Natural Product Research, 31, no. 15 (2017):1825-1830,
https://doi.org/10.1080/14786419.2017.1289209 . .

TY  - DATA
AU  - Đorđević, Neda O.
AU  - Novaković, Miroslav
AU  - Pejin, Boris
AU  - Mutić, Jelena
AU  - Vajs, Vlatka
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4467
AB  - Experimental details: standards and solvents; wine samples; Spectrophotometric analysis of total phenolic content; Determination of anti-DPPH radical activity; LC-MS/MS profiling of phenolic compounds; Multi-element analysis; Statistical analysis; Additional references. Figure S1. Representative LC-MS/MS chromatograms for the phenolic compounds analysed. Table S1. Total phenolic content and anti-DPPH radical activity of the red wines varieties selected. Table S2. The content of the phenolic compounds in the wine samples examined, determined by LC-MS/MS. Table S3. The contents of major and trace elements in the wine samples selected, determined by ICP-OES or ICP-MS. Table S4a. The content of ultratrace elements in the wine samples selected, determined by ICP-MS. Table S4b. The content of ultratrace elements in the wine samples selected, determined by ICP-MS. Table S5. Basic parameters of the analytes applied for the analysis of the compounds selected.
PB  - Taylor & Francis
T2  - Natural Product Research
T1  - Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro"
DO  - 10.6084/m9.figshare.4738396.v1
ER  - 

@misc{
author = "Đorđević, Neda O. and Novaković, Miroslav and Pejin, Boris and Mutić, Jelena and Vajs, Vlatka and Pajovic, Snezana B. and Tešević, Vele",
year = "2017",
abstract = "Experimental details: standards and solvents; wine samples; Spectrophotometric analysis of total phenolic content; Determination of anti-DPPH radical activity; LC-MS/MS profiling of phenolic compounds; Multi-element analysis; Statistical analysis; Additional references. Figure S1. Representative LC-MS/MS chromatograms for the phenolic compounds analysed. Table S1. Total phenolic content and anti-DPPH radical activity of the red wines varieties selected. Table S2. The content of the phenolic compounds in the wine samples examined, determined by LC-MS/MS. Table S3. The contents of major and trace elements in the wine samples selected, determined by ICP-OES or ICP-MS. Table S4a. The content of ultratrace elements in the wine samples selected, determined by ICP-MS. Table S4b. The content of ultratrace elements in the wine samples selected, determined by ICP-MS. Table S5. Basic parameters of the analytes applied for the analysis of the compounds selected.",
publisher = "Taylor & Francis",
journal = "Natural Product Research",
title = "Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro"",
doi = "10.6084/m9.figshare.4738396.v1"
}

Đorđević, N. O., Novaković, M., Pejin, B., Mutić, J., Vajs, V., Pajovic, S. B.,& Tešević, V.. (2017). Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro". in Natural Product Research
Taylor & Francis..
https://doi.org/10.6084/m9.figshare.4738396.v1

Đorđević NO, Novaković M, Pejin B, Mutić J, Vajs V, Pajovic SB, Tešević V. Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro". in Natural Product Research. 2017;.
doi:10.6084/m9.figshare.4738396.v1 .

Đorđević, Neda O., Novaković, Miroslav, Pejin, Boris, Mutić, Jelena, Vajs, Vlatka, Pajovic, Snezana B., Tešević, Vele, "Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro"" in Natural Product Research (2017),
https://doi.org/10.6084/m9.figshare.4738396.v1 . .

TY  - JOUR
AU  - Savikin, Katarina
AU  - Živković, Jelena Č.
AU  - Zdunić, Gordana
AU  - Gođevac, Dejan
AU  - Dordevic, Boban
AU  - Dojčinović, Biljana
AU  - Đorđević, Neda O.
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1396
AB  - Some primary and secondary metabolites, as well as mineral nutrients in pulp, peel and juice obtained from four Serbian indigenous apple cultivars (Kozara, Kolacara, Budimka and.Sumatovka) collected at two different developmental stages were studied. With advanced maturation soluble solids content, total and reducing sugars increased, while L-ascorbic acid content and titratable acidity decreased. Thirteen phenolic compounds were quantified using LC-MS/MS. The total phenolic content (TPC) ranged from 9.37 to 1440 mg/100 g fw, and 0.83 to 7.84 mg/100 g fw in peel and pulp samples, respectively. Quercetin derivatives were the major detected polyphenolic group. Majority of determined phenolic compounds were influenced by cultivar and the best sources were cultivars Kolgara and Budimka. The content of flavonols (with the exception of quercitrin) varied significantly depending on maturity at harvest. With regard to mineral analysis, K was the most abundant ranging from 104 to 158 mg/100 g fw in peel, 74.4 to 93.3 mg/100 g fw in pulp, and 77.1 to 91.5 mg/100 g fw in juice samples. Obtained results provide detailed information on nutritional potential and chemical composition of tested apple cultivars and thereby could encourage their wider cultivation and consumption
PB  - Academic Press Inc.
T2  - Journal of Food Composition and Analysis
T1  - Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages
VL  - 35
IS  - 2
SP  - 101
EP  - 111
DO  - 10.1016/j.jfca.2014.05.004
ER  - 

@article{
author = "Savikin, Katarina and Živković, Jelena Č. and Zdunić, Gordana and Gođevac, Dejan and Dordevic, Boban and Dojčinović, Biljana and Đorđević, Neda O.",
year = "2014",
abstract = "Some primary and secondary metabolites, as well as mineral nutrients in pulp, peel and juice obtained from four Serbian indigenous apple cultivars (Kozara, Kolacara, Budimka and.Sumatovka) collected at two different developmental stages were studied. With advanced maturation soluble solids content, total and reducing sugars increased, while L-ascorbic acid content and titratable acidity decreased. Thirteen phenolic compounds were quantified using LC-MS/MS. The total phenolic content (TPC) ranged from 9.37 to 1440 mg/100 g fw, and 0.83 to 7.84 mg/100 g fw in peel and pulp samples, respectively. Quercetin derivatives were the major detected polyphenolic group. Majority of determined phenolic compounds were influenced by cultivar and the best sources were cultivars Kolgara and Budimka. The content of flavonols (with the exception of quercitrin) varied significantly depending on maturity at harvest. With regard to mineral analysis, K was the most abundant ranging from 104 to 158 mg/100 g fw in peel, 74.4 to 93.3 mg/100 g fw in pulp, and 77.1 to 91.5 mg/100 g fw in juice samples. Obtained results provide detailed information on nutritional potential and chemical composition of tested apple cultivars and thereby could encourage their wider cultivation and consumption",
publisher = "Academic Press Inc.",
journal = "Journal of Food Composition and Analysis",
title = "Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages",
volume = "35",
number = "2",
pages = "101-111",
doi = "10.1016/j.jfca.2014.05.004"
}

Savikin, K., Živković, J. Č., Zdunić, G., Gođevac, D., Dordevic, B., Dojčinović, B.,& Đorđević, N. O.. (2014). Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages. in Journal of Food Composition and Analysis
Academic Press Inc.., 35(2), 101-111.
https://doi.org/10.1016/j.jfca.2014.05.004

Savikin K, Živković JČ, Zdunić G, Gođevac D, Dordevic B, Dojčinović B, Đorđević NO. Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages. in Journal of Food Composition and Analysis. 2014;35(2):101-111.
doi:10.1016/j.jfca.2014.05.004 .

Savikin, Katarina, Živković, Jelena Č., Zdunić, Gordana, Gođevac, Dejan, Dordevic, Boban, Dojčinović, Biljana, Đorđević, Neda O., "Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages" in Journal of Food Composition and Analysis, 35, no. 2 (2014):101-111,
https://doi.org/10.1016/j.jfca.2014.05.004 . .

TY  - JOUR
AU  - Veličković, Milovan M.
AU  - Radivojević, Dragan D.
AU  - Oparnica, Čedo Đ.
AU  - Nikićević, Ninoslav
AU  - Živković, Marijana
AU  - Đorđević, Neda O.
AU  - Vajs, Vlatka
AU  - Tešević, Vele
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1164
AB  - Medlar is the fruit of Mespilus germanica L. in the family of Rosaceae. The fruit can be eaten only if "bletted" (softened by frost or longer storage). The effect of the maturation stages on the volatile compounds of the medlar fruit was investigated during two different stages. Volatile flavour substances were isolated from the minced pulp of unripe and full ripe medlar fruits by simultaneous steam distillation extraction (SDE) with methylene chloride as the extracting solvent. The concentrate was analyzed by GC-FID-MS. Hexanoic and hexadecanoic acids were the predominant acids, hexanal and (E)-2-hexenal were the predominant aldehydes, (Z)-3-hexenol and hexanol were the predominant alcohols, with p-cymene, terpinen-4-ol, and γ-terpinene (the terpenes responsible for the characteristic medlar flavour) being also present. The C6 aliphatic compounds, such as hexanal and (E)-2-hexenal, were observed as the major volatile constituents in the green stage. In contrast, hexanol and (Z)-3-hexenol were the main volatiles in ripe fruits.
AB  - Mušmula (Mespilus germanica L) je voće iz porodice ruža (Rosaceae). Zeleni plodovi mušmule nisu jestivi već treba da ugnile (omekšaju usled mraza ili tokom čuvanja) pre nego što se koriste u ishrani. Efekat procesa sazrevanja na isparljive komponente ploda mušmule ispitivan je u dve različite faze njegove zrelosti. Isparljiva jedinjenja su izolovana iz izmrvljene pulpe nezrelih i zrelih plodova mušmule pomoću simultane destilacije vodenom parom i ekstrakcije metilen-hloridom. Koncentrovani uzorak je analiziran kombinacijom metoda GC-FID-MS. Heksanska i palmitinska kiselina su najzastupljenije kiseline, heksanal i (E)-2-heksenal su najzastupljeniji aldehidi, (Z)-3-heksenol i heksanol su najzastupljeniji alkoholi i p-cimen, terpinen-4-ol i γ-terpinen, terpeni odgovorni za karakterističnu aromu ploda mušmule, takođe su prisutni. C6 alifatična jedinjenja, kao što su heksanal i (E)-2-heksenal su nađeni kao glavne isparljive komponente zelenih mušmula. Za razliku od njih, heksanol, (Z)-3-heksenol su glavne komponente zrelih plodova mušmule.
PB  - Assoc Chemists & Chemical Engineers Of Serbia, Belgrade
T2  - Hemijska industrija
T1  - Volatile compounds in medlar fruit (Mespilus germanica L.) at two ripening stages
T1  - Isparljiva jedinjenja iz ploda mušmule (Mespilus germanica L.) u dve faze zrenja
VL  - 67
IS  - 3
SP  - 437
EP  - 441
DO  - 10.2298/HEMIND120611085V
ER  - 

@article{
author = "Veličković, Milovan M. and Radivojević, Dragan D. and Oparnica, Čedo Đ. and Nikićević, Ninoslav and Živković, Marijana and Đorđević, Neda O. and Vajs, Vlatka and Tešević, Vele",
year = "2013",
abstract = "Medlar is the fruit of Mespilus germanica L. in the family of Rosaceae. The fruit can be eaten only if "bletted" (softened by frost or longer storage). The effect of the maturation stages on the volatile compounds of the medlar fruit was investigated during two different stages. Volatile flavour substances were isolated from the minced pulp of unripe and full ripe medlar fruits by simultaneous steam distillation extraction (SDE) with methylene chloride as the extracting solvent. The concentrate was analyzed by GC-FID-MS. Hexanoic and hexadecanoic acids were the predominant acids, hexanal and (E)-2-hexenal were the predominant aldehydes, (Z)-3-hexenol and hexanol were the predominant alcohols, with p-cymene, terpinen-4-ol, and γ-terpinene (the terpenes responsible for the characteristic medlar flavour) being also present. The C6 aliphatic compounds, such as hexanal and (E)-2-hexenal, were observed as the major volatile constituents in the green stage. In contrast, hexanol and (Z)-3-hexenol were the main volatiles in ripe fruits., Mušmula (Mespilus germanica L) je voće iz porodice ruža (Rosaceae). Zeleni plodovi mušmule nisu jestivi već treba da ugnile (omekšaju usled mraza ili tokom čuvanja) pre nego što se koriste u ishrani. Efekat procesa sazrevanja na isparljive komponente ploda mušmule ispitivan je u dve različite faze njegove zrelosti. Isparljiva jedinjenja su izolovana iz izmrvljene pulpe nezrelih i zrelih plodova mušmule pomoću simultane destilacije vodenom parom i ekstrakcije metilen-hloridom. Koncentrovani uzorak je analiziran kombinacijom metoda GC-FID-MS. Heksanska i palmitinska kiselina su najzastupljenije kiseline, heksanal i (E)-2-heksenal su najzastupljeniji aldehidi, (Z)-3-heksenol i heksanol su najzastupljeniji alkoholi i p-cimen, terpinen-4-ol i γ-terpinen, terpeni odgovorni za karakterističnu aromu ploda mušmule, takođe su prisutni. C6 alifatična jedinjenja, kao što su heksanal i (E)-2-heksenal su nađeni kao glavne isparljive komponente zelenih mušmula. Za razliku od njih, heksanol, (Z)-3-heksenol su glavne komponente zrelih plodova mušmule.",
publisher = "Assoc Chemists & Chemical Engineers Of Serbia, Belgrade",
journal = "Hemijska industrija",
title = "Volatile compounds in medlar fruit (Mespilus germanica L.) at two ripening stages, Isparljiva jedinjenja iz ploda mušmule (Mespilus germanica L.) u dve faze zrenja",
volume = "67",
number = "3",
pages = "437-441",
doi = "10.2298/HEMIND120611085V"
}

Veličković, M. M., Radivojević, D. D., Oparnica, Č. Đ., Nikićević, N., Živković, M., Đorđević, N. O., Vajs, V.,& Tešević, V.. (2013). Volatile compounds in medlar fruit (Mespilus germanica L.) at two ripening stages. in Hemijska industrija
Assoc Chemists & Chemical Engineers Of Serbia, Belgrade., 67(3), 437-441.
https://doi.org/10.2298/HEMIND120611085V

Veličković MM, Radivojević DD, Oparnica ČĐ, Nikićević N, Živković M, Đorđević NO, Vajs V, Tešević V. Volatile compounds in medlar fruit (Mespilus germanica L.) at two ripening stages. in Hemijska industrija. 2013;67(3):437-441.
doi:10.2298/HEMIND120611085V .

Veličković, Milovan M., Radivojević, Dragan D., Oparnica, Čedo Đ., Nikićević, Ninoslav, Živković, Marijana, Đorđević, Neda O., Vajs, Vlatka, Tešević, Vele, "Volatile compounds in medlar fruit (Mespilus germanica L.) at two ripening stages" in Hemijska industrija, 67, no. 3 (2013):437-441,
https://doi.org/10.2298/HEMIND120611085V . .