TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Todorović, Nevena
AU  - Novaković, Irena
AU  - Pezo, Lato
AU  - Pejin, Boris
AU  - Maras, Vesna
AU  - Tešević, Vele
AU  - Pajovic, Snezana B.
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2485
AB  - Screens of antioxidant activity (AA) of various natural products have been a focus of the research community worldwide. This work aimed to differentiate selected samples of Merlot wines originated from Montenegro, with regard to phenolic profile and antioxidant capacity studied by survival rate, total sulfhydryl groups and activities of glutathione peroxidase (GPx), glutathione reductase and catalase in H2O2-stressed Saccharomyces cerevisiae cells. In this study, DPPH assay was also performed. Higher total phenolic content leads to an enhanced AA under both conditions. The same trend was observed for catechin and gallic acid, the most abundant phenolics in the examined wine samples. Finally, the findings of an Artificial Neural Network (ANN) model were in a good agreement (r(2) = 0.978) with the experimental data. All tested samples exhibited a protective effect in H2O2-stressed yeast cells. Pre-treatment with examined wines increased survival in H2O2-stressed cells and shifted antioxidative defense towards GPx-mediated defense. Finally, sensitivity analysis of obtained ANN model highlights the complexity of the impact that variations in the concentrations of specific phenolic components have on the antioxidant defense system.
PB  - MDPI
T2  - Molecules
T1  - Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine
VL  - 23
IS  - 8
DO  - 10.3390/molecules23081971
ER  - 

@article{
author = "Đorđević, Neda O. and Todorović, Nevena and Novaković, Irena and Pezo, Lato and Pejin, Boris and Maras, Vesna and Tešević, Vele and Pajovic, Snezana B.",
year = "2018",
abstract = "Screens of antioxidant activity (AA) of various natural products have been a focus of the research community worldwide. This work aimed to differentiate selected samples of Merlot wines originated from Montenegro, with regard to phenolic profile and antioxidant capacity studied by survival rate, total sulfhydryl groups and activities of glutathione peroxidase (GPx), glutathione reductase and catalase in H2O2-stressed Saccharomyces cerevisiae cells. In this study, DPPH assay was also performed. Higher total phenolic content leads to an enhanced AA under both conditions. The same trend was observed for catechin and gallic acid, the most abundant phenolics in the examined wine samples. Finally, the findings of an Artificial Neural Network (ANN) model were in a good agreement (r(2) = 0.978) with the experimental data. All tested samples exhibited a protective effect in H2O2-stressed yeast cells. Pre-treatment with examined wines increased survival in H2O2-stressed cells and shifted antioxidative defense towards GPx-mediated defense. Finally, sensitivity analysis of obtained ANN model highlights the complexity of the impact that variations in the concentrations of specific phenolic components have on the antioxidant defense system.",
publisher = "MDPI",
journal = "Molecules",
title = "Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine",
volume = "23",
number = "8",
doi = "10.3390/molecules23081971"
}

Đorđević, N. O., Todorović, N., Novaković, I., Pezo, L., Pejin, B., Maras, V., Tešević, V.,& Pajovic, S. B.. (2018). Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine. in Molecules
MDPI., 23(8).
https://doi.org/10.3390/molecules23081971

Đorđević NO, Todorović N, Novaković I, Pezo L, Pejin B, Maras V, Tešević V, Pajovic SB. Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine. in Molecules. 2018;23(8).
doi:10.3390/molecules23081971 .

Đorđević, Neda O., Todorović, Nevena, Novaković, Irena, Pezo, Lato, Pejin, Boris, Maras, Vesna, Tešević, Vele, Pajovic, Snezana B., "Antioxidant Activity of Selected Polyphenolics in Yeast Cells: The Case Study of Montenegrin Merlot Wine" in Molecules, 23, no. 8 (2018),
https://doi.org/10.3390/molecules23081971 . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2456
AB  - The overall aim of this paper was to compare the multielement composition and antioxidant capacity of two Montenegrin Merlot wines obtained from specific vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011. Elemental composition was analysed using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Additionally, antioxidant capacity was assessed by cyclic voltammetry. VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, all three wines are good source of essential elements and products with a significant antioxidant activity and specific geographical origin.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro
VL  - 32
IS  - 3
SP  - 247
EP  - 251
DO  - 10.1080/14786419.2017.1347171
ER  - 

@article{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav and Stanković, Dalibor and Mutić, Jelena and Pajovic, Snezana B. and Tešević, Vele",
year = "2018",
abstract = "The overall aim of this paper was to compare the multielement composition and antioxidant capacity of two Montenegrin Merlot wines obtained from specific vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011. Elemental composition was analysed using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Additionally, antioxidant capacity was assessed by cyclic voltammetry. VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, all three wines are good source of essential elements and products with a significant antioxidant activity and specific geographical origin.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro",
volume = "32",
number = "3",
pages = "247-251",
doi = "10.1080/14786419.2017.1347171"
}

Đorđević, N. O., Pejin, B., Novaković, M., Stanković, D., Mutić, J., Pajovic, S. B.,& Tešević, V.. (2018). Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 32(3), 247-251.
https://doi.org/10.1080/14786419.2017.1347171

Đorđević NO, Pejin B, Novaković M, Stanković D, Mutić J, Pajovic SB, Tešević V. Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro. in Natural Product Research. 2018;32(3):247-251.
doi:10.1080/14786419.2017.1347171 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav, Stanković, Dalibor, Mutić, Jelena, Pajovic, Snezana B., Tešević, Vele, "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro" in Natural Product Research, 32, no. 3 (2018):247-251,
https://doi.org/10.1080/14786419.2017.1347171 . .

TY  - DATA
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4468
AB  - Experimental details: Standards and solvents; Wine samples; Multielement analysis; Cyclic voltammetric determination of antioxidant capacity. Additional references. Supplementary Figure: Cyclic voltammograms obtained for the analysed wine samples during 2010 (a) and 2011 (b) vintages. Table S1. The contents of major and trace elements in analysed wine samples determined by ICP-OES or ICP-MS. Table S2. The content of ultratrace elements in analysed wine samples determined by ICP-MS. Table S3. Antioxidant potency composite index (ACI) of the selected wine samples determined 9 by cyclic voltammetry and scaled to relative percentages.
PB  - Taylor & Francis
T2  - Natural Product Research
T1  - Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro"
DO  - 10.6084/m9.figshare.5182369
ER  - 

@misc{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav and Stanković, Dalibor and Mutić, Jelena and Pajovic, Snezana B. and Tešević, Vele",
year = "2018",
abstract = "Experimental details: Standards and solvents; Wine samples; Multielement analysis; Cyclic voltammetric determination of antioxidant capacity. Additional references. Supplementary Figure: Cyclic voltammograms obtained for the analysed wine samples during 2010 (a) and 2011 (b) vintages. Table S1. The contents of major and trace elements in analysed wine samples determined by ICP-OES or ICP-MS. Table S2. The content of ultratrace elements in analysed wine samples determined by ICP-MS. Table S3. Antioxidant potency composite index (ACI) of the selected wine samples determined 9 by cyclic voltammetry and scaled to relative percentages.",
publisher = "Taylor & Francis",
journal = "Natural Product Research",
title = "Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro"",
doi = "10.6084/m9.figshare.5182369"
}

Đorđević, N. O., Pejin, B., Novaković, M., Stanković, D., Mutić, J., Pajovic, S. B.,& Tešević, V.. (2018). Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro". in Natural Product Research
Taylor & Francis..
https://doi.org/10.6084/m9.figshare.5182369

Đorđević NO, Pejin B, Novaković M, Stanković D, Mutić J, Pajovic SB, Tešević V. Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro". in Natural Product Research. 2018;.
doi:10.6084/m9.figshare.5182369 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav, Stanković, Dalibor, Mutić, Jelena, Pajovic, Snezana B., Tešević, Vele, "Supplementary material for: "Multielement analysis and antioxidant capacity of Merlot wine clones developed in Montenegro"" in Natural Product Research (2018),
https://doi.org/10.6084/m9.figshare.5182369 . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Pejin, Boris
AU  - Novaković, Miroslav
AU  - Stanković, Dalibor
AU  - Mutić, Jelena
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2154
AB  - The overall aim was to compare the quality of two Montenegrin Merlot wines obtained from new vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011, due to preliminary screening of the potential of novel Merlot vine clones for the wine industry. The content of phenolic compounds was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS). Elemental composition was analysed using inductively coupled plasma optical emission spectrometery (ICP-OES) and inductively coupled plasma mass spectrometery (ICP-MS)]. Additionaly, antioxidant capacity was assessed by cyclic voltammetry. Compared with the commercial one, both wine clones contained higher percent of major phenolic compounds (namely, gallic acid and catechin) with top values recorded for VCR1 both in 2010 (30.46 +/- 0.42 mg/1) and 2011 (28.12 +/- 0.29 mg/1). The same wines were enriched with epicatechin, resveratrol, myricetin and quercetin. Furthermore, VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, both new Montenegrin Merlot wines represent good candidates for the commercialised wines with an indication of geographical origin.
PB  - Elsevier
T2  - Scientia Horticulturae
T1  - Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro
VL  - 225
SP  - 505
EP  - 511
DO  - 10.1016/j.scienta.2017.07.045
ER  - 

@article{
author = "Đorđević, Neda O. and Pejin, Boris and Novaković, Miroslav and Stanković, Dalibor and Mutić, Jelena and Pajovic, Snezana B. and Tešević, Vele",
year = "2017",
abstract = "The overall aim was to compare the quality of two Montenegrin Merlot wines obtained from new vine clones (VCR1 and VCR 101) along with commercial Merlot wine throughout the consecutive vintages in 2010 and 2011, due to preliminary screening of the potential of novel Merlot vine clones for the wine industry. The content of phenolic compounds was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS). Elemental composition was analysed using inductively coupled plasma optical emission spectrometery (ICP-OES) and inductively coupled plasma mass spectrometery (ICP-MS)]. Additionaly, antioxidant capacity was assessed by cyclic voltammetry. Compared with the commercial one, both wine clones contained higher percent of major phenolic compounds (namely, gallic acid and catechin) with top values recorded for VCR1 both in 2010 (30.46 +/- 0.42 mg/1) and 2011 (28.12 +/- 0.29 mg/1). The same wines were enriched with epicatechin, resveratrol, myricetin and quercetin. Furthermore, VCR 1 wine from 2011 stood out for its elemental composition. On the other hand, antioxidant capacity of VCR 101 wines was the highest one for the both vintages. According to the experimental data obtained, both new Montenegrin Merlot wines represent good candidates for the commercialised wines with an indication of geographical origin.",
publisher = "Elsevier",
journal = "Scientia Horticulturae",
title = "Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro",
volume = "225",
pages = "505-511",
doi = "10.1016/j.scienta.2017.07.045"
}

Đorđević, N. O., Pejin, B., Novaković, M., Stanković, D., Mutić, J., Pajovic, S. B.,& Tešević, V.. (2017). Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro. in Scientia Horticulturae
Elsevier., 225, 505-511.
https://doi.org/10.1016/j.scienta.2017.07.045

Đorđević NO, Pejin B, Novaković M, Stanković D, Mutić J, Pajovic SB, Tešević V. Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro. in Scientia Horticulturae. 2017;225:505-511.
doi:10.1016/j.scienta.2017.07.045 .

Đorđević, Neda O., Pejin, Boris, Novaković, Miroslav, Stanković, Dalibor, Mutić, Jelena, Pajovic, Snezana B., Tešević, Vele, "Some chemical characteristics and antioxidant capacity of novel Merlot wine clones developed in Montenegro" in Scientia Horticulturae, 225 (2017):505-511,
https://doi.org/10.1016/j.scienta.2017.07.045 . .

TY  - JOUR
AU  - Đorđević, Neda O.
AU  - Novaković, Miroslav
AU  - Pejin, Boris
AU  - Mutić, Jelena
AU  - Vajs, Vlatka
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2252
AB  - Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010-2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R=0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products. [GRAPHICS] .
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Comparative analytical study of the selected wine varieties grown in Montenegro
VL  - 31
IS  - 15
SP  - 1825
EP  - 1830
DO  - 10.1080/14786419.2017.1289209
ER  - 

@article{
author = "Đorđević, Neda O. and Novaković, Miroslav and Pejin, Boris and Mutić, Jelena and Vajs, Vlatka and Pajovic, Snezana B. and Tešević, Vele",
year = "2017",
abstract = "Samples of the selected red wine varieties grown in Montenegro (Merlot, Cabernet Sauvignon and Vranac; vintages 2010-2012) were compared according to total phenolic content, anti-DPPH radical activity, phenolic profile and elemental composition. All the samples showed profound anti-DPPH radical activity, due to high content of total phenolic compounds (R=0.92). The most abundant phenolics were catechin and gallic acid with the highest values recorded for Merlot 2012 (43.22 and 28.65mg/L, respectively). In addition to this, the content of essential elements including the potentially toxic ones was within healthy (safe) level for all the samples analysed. This study has actually pointed out Merlot wine variety as the best quality one, though all three varieties may be used as safe and health-promoting nutritional products. [GRAPHICS] .",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Comparative analytical study of the selected wine varieties grown in Montenegro",
volume = "31",
number = "15",
pages = "1825-1830",
doi = "10.1080/14786419.2017.1289209"
}

Đorđević, N. O., Novaković, M., Pejin, B., Mutić, J., Vajs, V., Pajovic, S. B.,& Tešević, V.. (2017). Comparative analytical study of the selected wine varieties grown in Montenegro. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 31(15), 1825-1830.
https://doi.org/10.1080/14786419.2017.1289209

Đorđević NO, Novaković M, Pejin B, Mutić J, Vajs V, Pajovic SB, Tešević V. Comparative analytical study of the selected wine varieties grown in Montenegro. in Natural Product Research. 2017;31(15):1825-1830.
doi:10.1080/14786419.2017.1289209 .

Đorđević, Neda O., Novaković, Miroslav, Pejin, Boris, Mutić, Jelena, Vajs, Vlatka, Pajovic, Snezana B., Tešević, Vele, "Comparative analytical study of the selected wine varieties grown in Montenegro" in Natural Product Research, 31, no. 15 (2017):1825-1830,
https://doi.org/10.1080/14786419.2017.1289209 . .

TY  - DATA
AU  - Đorđević, Neda O.
AU  - Novaković, Miroslav
AU  - Pejin, Boris
AU  - Mutić, Jelena
AU  - Vajs, Vlatka
AU  - Pajovic, Snezana B.
AU  - Tešević, Vele
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4467
AB  - Experimental details: standards and solvents; wine samples; Spectrophotometric analysis of total phenolic content; Determination of anti-DPPH radical activity; LC-MS/MS profiling of phenolic compounds; Multi-element analysis; Statistical analysis; Additional references. Figure S1. Representative LC-MS/MS chromatograms for the phenolic compounds analysed. Table S1. Total phenolic content and anti-DPPH radical activity of the red wines varieties selected. Table S2. The content of the phenolic compounds in the wine samples examined, determined by LC-MS/MS. Table S3. The contents of major and trace elements in the wine samples selected, determined by ICP-OES or ICP-MS. Table S4a. The content of ultratrace elements in the wine samples selected, determined by ICP-MS. Table S4b. The content of ultratrace elements in the wine samples selected, determined by ICP-MS. Table S5. Basic parameters of the analytes applied for the analysis of the compounds selected.
PB  - Taylor & Francis
T2  - Natural Product Research
T1  - Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro"
DO  - 10.6084/m9.figshare.4738396.v1
ER  - 

@misc{
author = "Đorđević, Neda O. and Novaković, Miroslav and Pejin, Boris and Mutić, Jelena and Vajs, Vlatka and Pajovic, Snezana B. and Tešević, Vele",
year = "2017",
abstract = "Experimental details: standards and solvents; wine samples; Spectrophotometric analysis of total phenolic content; Determination of anti-DPPH radical activity; LC-MS/MS profiling of phenolic compounds; Multi-element analysis; Statistical analysis; Additional references. Figure S1. Representative LC-MS/MS chromatograms for the phenolic compounds analysed. Table S1. Total phenolic content and anti-DPPH radical activity of the red wines varieties selected. Table S2. The content of the phenolic compounds in the wine samples examined, determined by LC-MS/MS. Table S3. The contents of major and trace elements in the wine samples selected, determined by ICP-OES or ICP-MS. Table S4a. The content of ultratrace elements in the wine samples selected, determined by ICP-MS. Table S4b. The content of ultratrace elements in the wine samples selected, determined by ICP-MS. Table S5. Basic parameters of the analytes applied for the analysis of the compounds selected.",
publisher = "Taylor & Francis",
journal = "Natural Product Research",
title = "Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro"",
doi = "10.6084/m9.figshare.4738396.v1"
}

Đorđević, N. O., Novaković, M., Pejin, B., Mutić, J., Vajs, V., Pajovic, S. B.,& Tešević, V.. (2017). Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro". in Natural Product Research
Taylor & Francis..
https://doi.org/10.6084/m9.figshare.4738396.v1

Đorđević NO, Novaković M, Pejin B, Mutić J, Vajs V, Pajovic SB, Tešević V. Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro". in Natural Product Research. 2017;.
doi:10.6084/m9.figshare.4738396.v1 .

Đorđević, Neda O., Novaković, Miroslav, Pejin, Boris, Mutić, Jelena, Vajs, Vlatka, Pajovic, Snezana B., Tešević, Vele, "Supplementary material for: "Comparative analytical study of the selected wine varieties grown in Montenegro"" in Natural Product Research (2017),
https://doi.org/10.6084/m9.figshare.4738396.v1 . .