TY  - JOUR
AU  - Varničić, Miroslava
AU  - Zasheva, Iva
AU  - Haak, Edgar
AU  - Sundmacher, Kai
AU  - Vidakovic-Koch, Tanja
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5978
AB  - Electroenzymatic processes are interesting solutions for the development of new processes based on renewable feedstocks, renewable energies, and green catalysts. High-selectivity and sustainability of these processes are usually assumed. In this contribution, these two aspects were studied in more detail. In a membrane-less electroenzymatic reactor, 97% product selectivity at 80% glucose conversion to gluconic acid was determined. With the help of nuclear magnetic resonance spectroscopy, two main side products were identified. The yields of D-arabinose and formic acid can be controlled by the flow rate and the electroenzymatic reactor mode of operation (fuel cell or ion-pumping). The possible pathways for the side product formation have been discussed. The electroenzymatic cathode was found to be responsible for a decrease in selectivity. The choice of the enzymatic catalyst on the cathode side led to 100% selectivity of gluconic acid at somewhat reduced conversion. Furthermore, sustainability of the electroenzymatic process is estimated based on several sustainability indicators. Although some indicators (like Space Time Yield) are favorable for electroenzymatic process, the E-factor of electroenzymatic process has to improve significantly in order to compete with the fermentation process. This can be achieved by an increase of a cycle time and/or enzyme utilization which is currently low.
PB  - MDPI
T2  - Catalysts
T1  - Selectivity and sustainability of electroenzymatic process for glucose conversion to gluconic acid
VL  - 10
IS  - 3
SP  - 269
DO  - 10.3390/catal10030269
ER  - 

@article{
author = "Varničić, Miroslava and Zasheva, Iva and Haak, Edgar and Sundmacher, Kai and Vidakovic-Koch, Tanja",
year = "2020",
abstract = "Electroenzymatic processes are interesting solutions for the development of new processes based on renewable feedstocks, renewable energies, and green catalysts. High-selectivity and sustainability of these processes are usually assumed. In this contribution, these two aspects were studied in more detail. In a membrane-less electroenzymatic reactor, 97% product selectivity at 80% glucose conversion to gluconic acid was determined. With the help of nuclear magnetic resonance spectroscopy, two main side products were identified. The yields of D-arabinose and formic acid can be controlled by the flow rate and the electroenzymatic reactor mode of operation (fuel cell or ion-pumping). The possible pathways for the side product formation have been discussed. The electroenzymatic cathode was found to be responsible for a decrease in selectivity. The choice of the enzymatic catalyst on the cathode side led to 100% selectivity of gluconic acid at somewhat reduced conversion. Furthermore, sustainability of the electroenzymatic process is estimated based on several sustainability indicators. Although some indicators (like Space Time Yield) are favorable for electroenzymatic process, the E-factor of electroenzymatic process has to improve significantly in order to compete with the fermentation process. This can be achieved by an increase of a cycle time and/or enzyme utilization which is currently low.",
publisher = "MDPI",
journal = "Catalysts",
title = "Selectivity and sustainability of electroenzymatic process for glucose conversion to gluconic acid",
volume = "10",
number = "3",
pages = "269",
doi = "10.3390/catal10030269"
}

Varničić, M., Zasheva, I., Haak, E., Sundmacher, K.,& Vidakovic-Koch, T.. (2020). Selectivity and sustainability of electroenzymatic process for glucose conversion to gluconic acid. in Catalysts
MDPI., 10(3), 269.
https://doi.org/10.3390/catal10030269

Varničić M, Zasheva I, Haak E, Sundmacher K, Vidakovic-Koch T. Selectivity and sustainability of electroenzymatic process for glucose conversion to gluconic acid. in Catalysts. 2020;10(3):269.
doi:10.3390/catal10030269 .

Varničić, Miroslava, Zasheva, Iva, Haak, Edgar, Sundmacher, Kai, Vidakovic-Koch, Tanja, "Selectivity and sustainability of electroenzymatic process for glucose conversion to gluconic acid" in Catalysts, 10, no. 3 (2020):269,
https://doi.org/10.3390/catal10030269 . .