TY  - JOUR
AU  - Anđelković, Ljubica
AU  - Šuljagić, Marija
AU  - Pavlović, Vladimir
AU  - Mirković, Miljana
AU  - Vrbica, Boško
AU  - Novaković, Irena
AU  - Stanković, Dalibor
AU  - Kremenović, Aleksandar
AU  - Uskoković, Vuk
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7552
AB  - Metals and metal oxides have subpar antibacterial activities compared to those of small-molecule antibiotics, yet there are hopes that with proper compositional and structural adjustments this gap might be bridged. In this study, titanium dioxide (TiO2) nanoparticles were mechanically activated and combined with particulate silver through simple reduction process elicited by UV irradiation and assisted with the ultrasound. The resulting powders in various combinations (Ag vs. no Ag, activated vs. non-activated) were characterized using a range of experimental techniques and assessed for their antibacterial activities. The preparation procedure presented in this work prevails over the disadvantages of many chemical routes, most critically by avoiding the use of toxic substances. The mechanical activation did not reduce the particle size or crystallinity of TiO2 nor did it consistently alter the bandgap, yet it enabled the doubling of the amount of silver incorporable into the material. Further, while both mechanical activation and the addition of silver in the amount not exceeding 0.5 wt% produced barely detectable structural changes in the material, they both augmented its antibacterial activity. The precursor TiO2 powder produced no inhibition zone against any of the four bacterial species tested, while the mechanical activation of TiO2 led to the formation of distinct inhibition zones against each of the four bacterial species tested. The addition of silver to activated TiO2 further widened the inhibition zones and it also imparted the antibacterial activity to non-activated TiO2. The boost in the antibacterial activity achieved by the short mechanical activation was of a similar magnitude as the boost obtained after the addition of silver. The antibacterial activity was not different for different species when no silver was added to the system. However, with the addition of silver, species selectivity was obtained, as the composites were more effective against the two Gram-negative species (Escherichia coli and Klebsiella pneumoniae) than against the two Gram-positive ones (Staphylococcus aureus and Bacillus subtilis). The antibacterial activity increased with the addition of silver in the broth assay, but it was mediocre compared to that detected in the agar assay, attesting to the poor dispersability of the powders and their best performance when the bacterial cells migrate to the composite surface than vice versa. The findings of this study give hope that with appropriate microstructural or compositional alterations, the antibacterial activity of metal oxide powders and inorganic materials in general can be made comparable to that of small-molecule antibiotics.
PB  - Elsevier
T2  - Colloids and Surfaces A: Physicochemical and Engineering Aspects
T1  - Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles
VL  - 691
SP  - 133890
DO  - 10.1016/j.colsurfa.2024.133890
ER  - 

@article{
author = "Anđelković, Ljubica and Šuljagić, Marija and Pavlović, Vladimir and Mirković, Miljana and Vrbica, Boško and Novaković, Irena and Stanković, Dalibor and Kremenović, Aleksandar and Uskoković, Vuk",
year = "2024",
abstract = "Metals and metal oxides have subpar antibacterial activities compared to those of small-molecule antibiotics, yet there are hopes that with proper compositional and structural adjustments this gap might be bridged. In this study, titanium dioxide (TiO2) nanoparticles were mechanically activated and combined with particulate silver through simple reduction process elicited by UV irradiation and assisted with the ultrasound. The resulting powders in various combinations (Ag vs. no Ag, activated vs. non-activated) were characterized using a range of experimental techniques and assessed for their antibacterial activities. The preparation procedure presented in this work prevails over the disadvantages of many chemical routes, most critically by avoiding the use of toxic substances. The mechanical activation did not reduce the particle size or crystallinity of TiO2 nor did it consistently alter the bandgap, yet it enabled the doubling of the amount of silver incorporable into the material. Further, while both mechanical activation and the addition of silver in the amount not exceeding 0.5 wt% produced barely detectable structural changes in the material, they both augmented its antibacterial activity. The precursor TiO2 powder produced no inhibition zone against any of the four bacterial species tested, while the mechanical activation of TiO2 led to the formation of distinct inhibition zones against each of the four bacterial species tested. The addition of silver to activated TiO2 further widened the inhibition zones and it also imparted the antibacterial activity to non-activated TiO2. The boost in the antibacterial activity achieved by the short mechanical activation was of a similar magnitude as the boost obtained after the addition of silver. The antibacterial activity was not different for different species when no silver was added to the system. However, with the addition of silver, species selectivity was obtained, as the composites were more effective against the two Gram-negative species (Escherichia coli and Klebsiella pneumoniae) than against the two Gram-positive ones (Staphylococcus aureus and Bacillus subtilis). The antibacterial activity increased with the addition of silver in the broth assay, but it was mediocre compared to that detected in the agar assay, attesting to the poor dispersability of the powders and their best performance when the bacterial cells migrate to the composite surface than vice versa. The findings of this study give hope that with appropriate microstructural or compositional alterations, the antibacterial activity of metal oxide powders and inorganic materials in general can be made comparable to that of small-molecule antibiotics.",
publisher = "Elsevier",
journal = "Colloids and Surfaces A: Physicochemical and Engineering Aspects",
title = "Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles",
volume = "691",
pages = "133890",
doi = "10.1016/j.colsurfa.2024.133890"
}

Anđelković, L., Šuljagić, M., Pavlović, V., Mirković, M., Vrbica, B., Novaković, I., Stanković, D., Kremenović, A.,& Uskoković, V.. (2024). Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles. in Colloids and Surfaces A: Physicochemical and Engineering Aspects
Elsevier., 691, 133890.
https://doi.org/10.1016/j.colsurfa.2024.133890

Anđelković L, Šuljagić M, Pavlović V, Mirković M, Vrbica B, Novaković I, Stanković D, Kremenović A, Uskoković V. Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles. in Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2024;691:133890.
doi:10.1016/j.colsurfa.2024.133890 .

Anđelković, Ljubica, Šuljagić, Marija, Pavlović, Vladimir, Mirković, Miljana, Vrbica, Boško, Novaković, Irena, Stanković, Dalibor, Kremenović, Aleksandar, Uskoković, Vuk, "Mechanical activation and silver supplementation as determinants of the antibacterial activity of titanium dioxide nanoparticles" in Colloids and Surfaces A: Physicochemical and Engineering Aspects, 691 (2024):133890,
https://doi.org/10.1016/j.colsurfa.2024.133890 . .

TY  - CONF
AU  - Šuljagić, Marija
AU  - Petronijević, Ivan
AU  - Mirković, Miljana
AU  - Kremenović, Aleksandar
AU  - Džunuzović, Adis
AU  - Pavlović, Vladimir
AU  - Kalezić-Glišović, Aleksandra
AU  - Anđelković, Ljubica
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6328
AB  - In order to examine the influence of phase composition and sintering temperature on the functional properties of perovskite/spinel composites, BaTiO3/NixZn1−xFe2O4 (x = 0, 0.5, 1), NiFe2O4, ZnFe2O4, and Ni0.5Zn0.5Fe2O4 were in situ prepared by thermal decomposition onto BaTiO3 surface. Acetylacetonate complexes were used as the precursors. The obtained powders were compressed to pellets and sintered at 1150 °C and 1300 °C. X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM) coupled with electron dispersive spectroscopy (EDS) were used for the comprehensive investigation of phase composition and morphology. The magnetic, dielectric, and ferroelectric properties were performed in detail. The optimal phase composition was found in the BaTiO3/NiFe2O4 composite sintered at 1150 °C, which resulted in a wide frequency range stability. Furthermore, particular phase composition led to suitable properties such as low conductivity and ideal-like hysteresis loop behavior [1]. These functional properties of BaTiO3/NiFe2O4 make this composite a “material of choice“ for further studies on applications of multiferroic devices.
AB  - U cilju ispitivanja uticaja faznog sastava i temperature sinterovanja na funkcionalna svojstva perovskit/spinel kompozita BaTiO3/NixZn1−xFe2O4 (x = 0, 0,5, 1), NiFe2O4, ZnFe2O4, i Ni0,5Zn0,5Fe2O4 pripremljeni su in situ metodom termalne dekompozicije. U sintezi su korišćeni acetilacetonatni kompleksi kao prekursori. Dobijeni prahovi su komprimovani u tablete i sinterovani na 1150 °C i 1300 °C. Za detaljno ispitivanje faznog sastava i morfologije sintetisanih kompozita korišćene su metode rendgenske difrakcije praha (XRPD) i skenirajuće elektronske mikroskopije (SEM) spregnute sa energetsko disperzivnom spektroskopijom (EDS). Ispitivana su i magnetna, dielektrična i feroelektrična svojstva sinterovanih kompozita. Ustanovljeno je da optimalni fazni sastav pronađen kod kompozita BaTiO3/NiFe2O4 sinterovanog na 1150 °C dovodi do stabilnosti u širokom opsegu frekvencija. Optimalni fazni sastav pomenutog kompozita povoljno je uticao na funkcionalna svojstva kao što su niska provodnost i feroelektrično ponašenje koje se ogleda u zadovoljavajućem izgledu histerezisa [1]. Ova svojstva nedvosmisleno ukazuju da je kompozit BaTiO3/NiFe2O4 odgovarajući izbor za dalja istraživanja posvećena primeni multiferoičnih materijala.
PB  - Belgrade, Serbia : Serbian Cristallographic Soceity / Beograd, Srbija : Srpsko kristalografsko društvo
C3  - 28th Conference of the Serbian Crystallographic Society - Abstracts, June 14–15th, 2023 Čačak, Serbia / XXVIII Konferencija Srpskog kristalografskog društva - Izvodi radova, Jun 14–15, 2023 Čačak, Srbija
T1  - BaTiO3/NixZn1-xFe2O4 (x =0, 0.5, 1) composites synthesized by thermal decomposition: The influence of phase composition and sintering temperature on their physical properties
T1  - Uticaj faznog sastava i temperature sinterovanja na fizička svojstva BaTiO3/NixZn1-xFe2O4 (x =0, 0.5, 1) kompozita sintetisanih metodom termalne dekompozicije
SP  - 36
EP  - 37
UR  - https://hdl.handle.net/21.15107/rcub_cer_6328
ER  - 

@conference{
author = "Šuljagić, Marija and Petronijević, Ivan and Mirković, Miljana and Kremenović, Aleksandar and Džunuzović, Adis and Pavlović, Vladimir and Kalezić-Glišović, Aleksandra and Anđelković, Ljubica",
year = "2023",
abstract = "In order to examine the influence of phase composition and sintering temperature on the functional properties of perovskite/spinel composites, BaTiO3/NixZn1−xFe2O4 (x = 0, 0.5, 1), NiFe2O4, ZnFe2O4, and Ni0.5Zn0.5Fe2O4 were in situ prepared by thermal decomposition onto BaTiO3 surface. Acetylacetonate complexes were used as the precursors. The obtained powders were compressed to pellets and sintered at 1150 °C and 1300 °C. X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM) coupled with electron dispersive spectroscopy (EDS) were used for the comprehensive investigation of phase composition and morphology. The magnetic, dielectric, and ferroelectric properties were performed in detail. The optimal phase composition was found in the BaTiO3/NiFe2O4 composite sintered at 1150 °C, which resulted in a wide frequency range stability. Furthermore, particular phase composition led to suitable properties such as low conductivity and ideal-like hysteresis loop behavior [1]. These functional properties of BaTiO3/NiFe2O4 make this composite a “material of choice“ for further studies on applications of multiferroic devices., U cilju ispitivanja uticaja faznog sastava i temperature sinterovanja na funkcionalna svojstva perovskit/spinel kompozita BaTiO3/NixZn1−xFe2O4 (x = 0, 0,5, 1), NiFe2O4, ZnFe2O4, i Ni0,5Zn0,5Fe2O4 pripremljeni su in situ metodom termalne dekompozicije. U sintezi su korišćeni acetilacetonatni kompleksi kao prekursori. Dobijeni prahovi su komprimovani u tablete i sinterovani na 1150 °C i 1300 °C. Za detaljno ispitivanje faznog sastava i morfologije sintetisanih kompozita korišćene su metode rendgenske difrakcije praha (XRPD) i skenirajuće elektronske mikroskopije (SEM) spregnute sa energetsko disperzivnom spektroskopijom (EDS). Ispitivana su i magnetna, dielektrična i feroelektrična svojstva sinterovanih kompozita. Ustanovljeno je da optimalni fazni sastav pronađen kod kompozita BaTiO3/NiFe2O4 sinterovanog na 1150 °C dovodi do stabilnosti u širokom opsegu frekvencija. Optimalni fazni sastav pomenutog kompozita povoljno je uticao na funkcionalna svojstva kao što su niska provodnost i feroelektrično ponašenje koje se ogleda u zadovoljavajućem izgledu histerezisa [1]. Ova svojstva nedvosmisleno ukazuju da je kompozit BaTiO3/NiFe2O4 odgovarajući izbor za dalja istraživanja posvećena primeni multiferoičnih materijala.",
publisher = "Belgrade, Serbia : Serbian Cristallographic Soceity / Beograd, Srbija : Srpsko kristalografsko društvo",
journal = "28th Conference of the Serbian Crystallographic Society - Abstracts, June 14–15th, 2023 Čačak, Serbia / XXVIII Konferencija Srpskog kristalografskog društva - Izvodi radova, Jun 14–15, 2023 Čačak, Srbija",
title = "BaTiO3/NixZn1-xFe2O4 (x =0, 0.5, 1) composites synthesized by thermal decomposition: The influence of phase composition and sintering temperature on their physical properties, Uticaj faznog sastava i temperature sinterovanja na fizička svojstva BaTiO3/NixZn1-xFe2O4 (x =0, 0.5, 1) kompozita sintetisanih metodom termalne dekompozicije",
pages = "36-37",
url = "https://hdl.handle.net/21.15107/rcub_cer_6328"
}

Šuljagić, M., Petronijević, I., Mirković, M., Kremenović, A., Džunuzović, A., Pavlović, V., Kalezić-Glišović, A.,& Anđelković, L.. (2023). BaTiO3/NixZn1-xFe2O4 (x =0, 0.5, 1) composites synthesized by thermal decomposition: The influence of phase composition and sintering temperature on their physical properties. in 28th Conference of the Serbian Crystallographic Society - Abstracts, June 14–15th, 2023 Čačak, Serbia / XXVIII Konferencija Srpskog kristalografskog društva - Izvodi radova, Jun 14–15, 2023 Čačak, Srbija
Belgrade, Serbia : Serbian Cristallographic Soceity / Beograd, Srbija : Srpsko kristalografsko društvo., 36-37.
https://hdl.handle.net/21.15107/rcub_cer_6328

Šuljagić M, Petronijević I, Mirković M, Kremenović A, Džunuzović A, Pavlović V, Kalezić-Glišović A, Anđelković L. BaTiO3/NixZn1-xFe2O4 (x =0, 0.5, 1) composites synthesized by thermal decomposition: The influence of phase composition and sintering temperature on their physical properties. in 28th Conference of the Serbian Crystallographic Society - Abstracts, June 14–15th, 2023 Čačak, Serbia / XXVIII Konferencija Srpskog kristalografskog društva - Izvodi radova, Jun 14–15, 2023 Čačak, Srbija. 2023;:36-37.
https://hdl.handle.net/21.15107/rcub_cer_6328 .

Šuljagić, Marija, Petronijević, Ivan, Mirković, Miljana, Kremenović, Aleksandar, Džunuzović, Adis, Pavlović, Vladimir, Kalezić-Glišović, Aleksandra, Anđelković, Ljubica, "BaTiO3/NixZn1-xFe2O4 (x =0, 0.5, 1) composites synthesized by thermal decomposition: The influence of phase composition and sintering temperature on their physical properties" in 28th Conference of the Serbian Crystallographic Society - Abstracts, June 14–15th, 2023 Čačak, Serbia / XXVIII Konferencija Srpskog kristalografskog društva - Izvodi radova, Jun 14–15, 2023 Čačak, Srbija (2023):36-37,
https://hdl.handle.net/21.15107/rcub_cer_6328 .

TY  - JOUR
AU  - Šuljagić, Marija
AU  - Kremenović, Aleksandar
AU  - Petronijević, Ivan
AU  - Džunuzović, Adis
AU  - Mirković, Miljana
AU  - Pavlović, Vladimir
AU  - Anđelković, Ljubica
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6643
AB  - To investigate the effect of synthesis procedure and sintering temperature on the functional properties of perovskite/spinel ceramics, BaTiO3/CoFe2O4 composites were prepared by thermal decomposition, coprecipitation, and microemulsion method, and sintered at 1150°C and 1300°C. The phase composition and morphology of as-prepared powders as well as sintered ceramics were thoroughly examined by X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM) coupled with electron dispersive spectroscopy (EDS). The dielectric and ferroelectric measurements were performed in detail. Generally, the samples sintered at 1300°C had better performances than those sintered at 1150°C. The composite synthesized by thermal decomposition and sintered at 1300 °C stands out among other prepared BaTiO3/CoFe2O4 ceramics, owing to high stability in the wide frequency range and low leakage currents. The obtained results indicate that such composite might be successfully applied as a functional multiferroic.
AB  - У циљу испитивања утицаја методе синтезе као и температуре синтеровања на функционална својства керамике перовскитно/спинелне структуре, синтетисани су BaTiO3/CoFe2O4 композити методама термалне декомпозиције, копреципитације и микроемулзије, а затим синтеровани на 1150 °C и 1300 °C. Фазни састав и морфологија синтетисаних узорака детаљно су испитани пре и после синтеровања помоћу рендгенске дифракције на праху (XRPD) и скенирајуће електронске микроскпије (SEM) спрегнуте са елекрон дисперзивном спектроскопијом (EDS). Изведена су опсежна испитивања како диелектричних, тако и фероелектричних својстава датих композита. У већини случајева узорци синтеровани на 1300 °C показали су боља својства од узорака синтерованих на 1150 °C. Композит синтетисан методом термалне декомпозиције и синтерован на 1300 °C издваја се од осталих синтетисаних BaTiO3/CoFe2O4 узорака захваљујући великој стабилносту у широком фреквентном опсегу и малим струјама цурења. Добијени резултати недвосмислено указују да истакнути композит може бити успешно примењен као функционални мултифероик.
PB  - Association for ETRAN Society
T2  - Science of Sintering
T1  - Understanding the  Effect of Synthesis and Sintering Temperature on the Functional Properties of Barium Titanate/ Cobalt Ferrite  Composites
VL  - 55
SP  - 367
EP  - 381
DO  - 10.2298/SOS220512013S
ER  - 

@article{
author = "Šuljagić, Marija and Kremenović, Aleksandar and Petronijević, Ivan and Džunuzović, Adis and Mirković, Miljana and Pavlović, Vladimir and Anđelković, Ljubica",
year = "2023",
abstract = "To investigate the effect of synthesis procedure and sintering temperature on the functional properties of perovskite/spinel ceramics, BaTiO3/CoFe2O4 composites were prepared by thermal decomposition, coprecipitation, and microemulsion method, and sintered at 1150°C and 1300°C. The phase composition and morphology of as-prepared powders as well as sintered ceramics were thoroughly examined by X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM) coupled with electron dispersive spectroscopy (EDS). The dielectric and ferroelectric measurements were performed in detail. Generally, the samples sintered at 1300°C had better performances than those sintered at 1150°C. The composite synthesized by thermal decomposition and sintered at 1300 °C stands out among other prepared BaTiO3/CoFe2O4 ceramics, owing to high stability in the wide frequency range and low leakage currents. The obtained results indicate that such composite might be successfully applied as a functional multiferroic., У циљу испитивања утицаја методе синтезе као и температуре синтеровања на функционална својства керамике перовскитно/спинелне структуре, синтетисани су BaTiO3/CoFe2O4 композити методама термалне декомпозиције, копреципитације и микроемулзије, а затим синтеровани на 1150 °C и 1300 °C. Фазни састав и морфологија синтетисаних узорака детаљно су испитани пре и после синтеровања помоћу рендгенске дифракције на праху (XRPD) и скенирајуће електронске микроскпије (SEM) спрегнуте са елекрон дисперзивном спектроскопијом (EDS). Изведена су опсежна испитивања како диелектричних, тако и фероелектричних својстава датих композита. У већини случајева узорци синтеровани на 1300 °C показали су боља својства од узорака синтерованих на 1150 °C. Композит синтетисан методом термалне декомпозиције и синтерован на 1300 °C издваја се од осталих синтетисаних BaTiO3/CoFe2O4 узорака захваљујући великој стабилносту у широком фреквентном опсегу и малим струјама цурења. Добијени резултати недвосмислено указују да истакнути композит може бити успешно примењен као функционални мултифероик.",
publisher = "Association for ETRAN Society",
journal = "Science of Sintering",
title = "Understanding the  Effect of Synthesis and Sintering Temperature on the Functional Properties of Barium Titanate/ Cobalt Ferrite  Composites",
volume = "55",
pages = "367-381",
doi = "10.2298/SOS220512013S"
}

Šuljagić, M., Kremenović, A., Petronijević, I., Džunuzović, A., Mirković, M., Pavlović, V.,& Anđelković, L.. (2023). Understanding the  Effect of Synthesis and Sintering Temperature on the Functional Properties of Barium Titanate/ Cobalt Ferrite  Composites. in Science of Sintering
Association for ETRAN Society., 55, 367-381.
https://doi.org/10.2298/SOS220512013S

Šuljagić M, Kremenović A, Petronijević I, Džunuzović A, Mirković M, Pavlović V, Anđelković L. Understanding the  Effect of Synthesis and Sintering Temperature on the Functional Properties of Barium Titanate/ Cobalt Ferrite  Composites. in Science of Sintering. 2023;55:367-381.
doi:10.2298/SOS220512013S .

Šuljagić, Marija, Kremenović, Aleksandar, Petronijević, Ivan, Džunuzović, Adis, Mirković, Miljana, Pavlović, Vladimir, Anđelković, Ljubica, "Understanding the  Effect of Synthesis and Sintering Temperature on the Functional Properties of Barium Titanate/ Cobalt Ferrite  Composites" in Science of Sintering, 55 (2023):367-381,
https://doi.org/10.2298/SOS220512013S . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Malagurski, Ivana
AU  - Lazić, Jelena
AU  - Jeremić, Sanja
AU  - Pavlović, Vladimir
AU  - Prlainović, Nevena
AU  - Maksimović, Vesna
AU  - Ćosović, Vladan
AU  - Atanase, Leonard Ionut
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5690
AB  - The quest for sustainable biomaterials with excellent biocompatibility and tailorable
properties has put polyhydroxyalkanoates (PHAs) into the research spotlight. However, high production
costs and the lack of bioactivity limit their market penetration. To address this, poly(3-
hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was combined with a bacterial pigment with strong
anticancer activity, prodigiosin (PG), to obtain functionally enhanced PHBV-based biomaterials. The
samples were produced in the form of films 115.6–118.8  m in thickness using the solvent casting
method. The effects of PG incorporation on the physical properties (morphology, biopolymer crystallinity
and thermal stability) and functionality of the obtained biomaterials were investigated. PG
has acted as a nucleating agent, in turn affecting the degree of crystallinity, thermal stability and
morphology of the films. All samples with PG had a more organized internal structure and higher
melting and degradation temperatures. The calculated degree of crystallinity of the PHBV copolymer
was 53%, while the PG1, PG3 and PG3 films had values of 64.0%, 63.9% and 69.2%, respectively.
Cytotoxicity studies have shown the excellent anticancer activity of films against HCT116 (colon
cancer) cells, thus advancing PHBV biomedical application potential.
PB  - Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)
T2  - International Journal of Molecular Sciences
T1  - Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin
VL  - 24
SP  - 1906
DO  - 10.3390/ijms24031906
ER  - 

@article{
author = "Ponjavić, Marijana and Malagurski, Ivana and Lazić, Jelena and Jeremić, Sanja and Pavlović, Vladimir and Prlainović, Nevena and Maksimović, Vesna and Ćosović, Vladan and Atanase, Leonard Ionut",
year = "2023",
abstract = "The quest for sustainable biomaterials with excellent biocompatibility and tailorable
properties has put polyhydroxyalkanoates (PHAs) into the research spotlight. However, high production
costs and the lack of bioactivity limit their market penetration. To address this, poly(3-
hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was combined with a bacterial pigment with strong
anticancer activity, prodigiosin (PG), to obtain functionally enhanced PHBV-based biomaterials. The
samples were produced in the form of films 115.6–118.8  m in thickness using the solvent casting
method. The effects of PG incorporation on the physical properties (morphology, biopolymer crystallinity
and thermal stability) and functionality of the obtained biomaterials were investigated. PG
has acted as a nucleating agent, in turn affecting the degree of crystallinity, thermal stability and
morphology of the films. All samples with PG had a more organized internal structure and higher
melting and degradation temperatures. The calculated degree of crystallinity of the PHBV copolymer
was 53%, while the PG1, PG3 and PG3 films had values of 64.0%, 63.9% and 69.2%, respectively.
Cytotoxicity studies have shown the excellent anticancer activity of films against HCT116 (colon
cancer) cells, thus advancing PHBV biomedical application potential.",
publisher = "Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "International Journal of Molecular Sciences",
title = "Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin",
volume = "24",
pages = "1906",
doi = "10.3390/ijms24031906"
}

Ponjavić, M., Malagurski, I., Lazić, J., Jeremić, S., Pavlović, V., Prlainović, N., Maksimović, V., Ćosović, V.,& Atanase, L. I.. (2023). Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin. in International Journal of Molecular Sciences
Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)., 24, 1906.
https://doi.org/10.3390/ijms24031906

Ponjavić M, Malagurski I, Lazić J, Jeremić S, Pavlović V, Prlainović N, Maksimović V, Ćosović V, Atanase LI. Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin. in International Journal of Molecular Sciences. 2023;24:1906.
doi:10.3390/ijms24031906 .

Ponjavić, Marijana, Malagurski, Ivana, Lazić, Jelena, Jeremić, Sanja, Pavlović, Vladimir, Prlainović, Nevena, Maksimović, Vesna, Ćosović, Vladan, Atanase, Leonard Ionut, "Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin" in International Journal of Molecular Sciences, 24 (2023):1906,
https://doi.org/10.3390/ijms24031906 . .

TY  - CONF
AU  - Mirković, Miljana
AU  - Sknepnek, Aleksandra
AU  - Miletić, Dunja
AU  - Pavlović, Vladimir
AU  - Đukić, Dunja
AU  - Šuljagić, Marija
AU  - Anđelković, Ljubica
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6783
AB  - Hydroxyapatite Ca10(PO4)6(OH)2 - HAp presents natural construction material for bones and teeth and therefore is considered biocompatible, and has various applications in fields such as biomedicine, drug delivery, and as a biomarker. Considering nanoceramics' high specific surface area and antimicrobial activity, they can be used as potential antimicrobial materials. Bacterial cellulose (BC) is a biopolymer that stands out in its biodegradability, biocompatibility, and high water retention capacity, but also lacks functional properties. The main goal of this study is to create a newly designed composite material with the functionalization of cellulose by hydroxyapatite with antimicrobial properties. Hydroxyapatite material was incorporated in wet cellulose during the precipitation synthesis reaction. Obtained BC-HAp material was structurally and phase investigated by the XRD method. The morphology of obtained material was done by SEM, and appropriate functional groups were determined by the FTIR method. According to antimicrobial results investigated composite is shown proper antimicrobial activity.
PB  - Faculty of Technology, University of Novi Sad, Bul. cara Lazara 1, 21000 Novi Sad, Serbia
C3  - Programme and book of abstracts / 15th ECerS Conference for Young Scientists in Ceramics, October 11-14, 2023, Novi Sad
T1  - Synthesis and characterization of cellulose-hydroxyapatite composite material with proper antimicrobial properties
SP  - 70
EP  - 70
UR  - https://hdl.handle.net/21.15107/rcub_cer_6783
ER  - 

@conference{
author = "Mirković, Miljana and Sknepnek, Aleksandra and Miletić, Dunja and Pavlović, Vladimir and Đukić, Dunja and Šuljagić, Marija and Anđelković, Ljubica",
year = "2023",
abstract = "Hydroxyapatite Ca10(PO4)6(OH)2 - HAp presents natural construction material for bones and teeth and therefore is considered biocompatible, and has various applications in fields such as biomedicine, drug delivery, and as a biomarker. Considering nanoceramics' high specific surface area and antimicrobial activity, they can be used as potential antimicrobial materials. Bacterial cellulose (BC) is a biopolymer that stands out in its biodegradability, biocompatibility, and high water retention capacity, but also lacks functional properties. The main goal of this study is to create a newly designed composite material with the functionalization of cellulose by hydroxyapatite with antimicrobial properties. Hydroxyapatite material was incorporated in wet cellulose during the precipitation synthesis reaction. Obtained BC-HAp material was structurally and phase investigated by the XRD method. The morphology of obtained material was done by SEM, and appropriate functional groups were determined by the FTIR method. According to antimicrobial results investigated composite is shown proper antimicrobial activity.",
publisher = "Faculty of Technology, University of Novi Sad, Bul. cara Lazara 1, 21000 Novi Sad, Serbia",
journal = "Programme and book of abstracts / 15th ECerS Conference for Young Scientists in Ceramics, October 11-14, 2023, Novi Sad",
title = "Synthesis and characterization of cellulose-hydroxyapatite composite material with proper antimicrobial properties",
pages = "70-70",
url = "https://hdl.handle.net/21.15107/rcub_cer_6783"
}

Mirković, M., Sknepnek, A., Miletić, D., Pavlović, V., Đukić, D., Šuljagić, M.,& Anđelković, L.. (2023). Synthesis and characterization of cellulose-hydroxyapatite composite material with proper antimicrobial properties. in Programme and book of abstracts / 15th ECerS Conference for Young Scientists in Ceramics, October 11-14, 2023, Novi Sad
Faculty of Technology, University of Novi Sad, Bul. cara Lazara 1, 21000 Novi Sad, Serbia., 70-70.
https://hdl.handle.net/21.15107/rcub_cer_6783

Mirković M, Sknepnek A, Miletić D, Pavlović V, Đukić D, Šuljagić M, Anđelković L. Synthesis and characterization of cellulose-hydroxyapatite composite material with proper antimicrobial properties. in Programme and book of abstracts / 15th ECerS Conference for Young Scientists in Ceramics, October 11-14, 2023, Novi Sad. 2023;:70-70.
https://hdl.handle.net/21.15107/rcub_cer_6783 .

Mirković, Miljana, Sknepnek, Aleksandra, Miletić, Dunja, Pavlović, Vladimir, Đukić, Dunja, Šuljagić, Marija, Anđelković, Ljubica, "Synthesis and characterization of cellulose-hydroxyapatite composite material with proper antimicrobial properties" in Programme and book of abstracts / 15th ECerS Conference for Young Scientists in Ceramics, October 11-14, 2023, Novi Sad (2023):70-70,
https://hdl.handle.net/21.15107/rcub_cer_6783 .

TY  - JOUR
AU  - Labus, Nebojsa
AU  - Krstić, Jugoslav
AU  - Matijašević, Srđan
AU  - Pavlović, Vladimir
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7187
AB  - Powder mixture consisted of ZnO, Mn2O3 (MnCO3) and Fe2O3 blended powders, was found laminating during compaction. Polyvinyl alcohol (PVA) and a combination of PVA with polyethylene glycol (PEG) added as a plasticizer, were introduced as polymer binders to improve the compaction of oxide mixtures. It has been done by forming a suspension of oxide mixture and varying the polymer solution concentration and composition. By evaporating the solvent, new materials were obtained, which consist of oxide particles bound via polymer. In such a manner obtained hybrid materials were characterized with attenuated total reflection Fourier transformed infrared (ATR-FTIR) spectroscopy, differential thermal analysis (DTA) and transmission electron microscopy (TEM). The oxide polymer material was compacted at 200 MPa and the expansion of this compact during heating was monitored in temperature range up to 550ºC with dilatometer. It was found that PVA forms graft polymer with PEG and specific interaction with oxide particles surface was revealed.
AB  - Смеша прахова састављена од ZnO, Mn2O3 (MnCO3) и Fe2O3 комбинацијепрахова је показивала ламинацију током пресовања. Поливинил алкохол (PVA) икомбинација PVA са полиетилен гликолом (PEG) који је додат као пластификатор, сууведени као полимерно везиво за пресовање оксидних прахова. Везиво је уведено такошто је формирана суспензија смеше различитих оксида прахова у полимерномраствору. Концентрације полимера и састави су варирани. Уклањањем растварачадобијени су нови материјали који се састоје од честица оксида повезаних полимерима.Ови хибридни материјали окарактерисани су методама ометене тоталне рефлексијефурије трансформисане инфрацрвене спектроскопије (ATR-FTIR) као идиференцијалне термичке анализе (DTA). Микроструктура је посматранатрансмисоном електронском микроскопијом (TEM). Оксид-полимер материјали супресовани на притиску од 200 MPa и ширење испреска током грејања је праћено у температурском опсегу од собне до 550ºC употребом дилатометра. Нађено је да PVAформира графт полимер са PEG и да постоји специфична интеракција полимера саповршином честица оксида.
PB  - Belgrade : Association for ETRAN Society
T2  - Science of Sintering
T1  - Oxide Powder Mixture with Poly-vinyl Alcohol (PVA) and added Polyethylene Glycol (PEG) as Plasticizer
VL  - 55
SP  - 189
EP  - 2023
DO  - 10.2298/SOS220828005L
ER  - 

@article{
author = "Labus, Nebojsa and Krstić, Jugoslav and Matijašević, Srđan and Pavlović, Vladimir",
year = "2023",
abstract = "Powder mixture consisted of ZnO, Mn2O3 (MnCO3) and Fe2O3 blended powders, was found laminating during compaction. Polyvinyl alcohol (PVA) and a combination of PVA with polyethylene glycol (PEG) added as a plasticizer, were introduced as polymer binders to improve the compaction of oxide mixtures. It has been done by forming a suspension of oxide mixture and varying the polymer solution concentration and composition. By evaporating the solvent, new materials were obtained, which consist of oxide particles bound via polymer. In such a manner obtained hybrid materials were characterized with attenuated total reflection Fourier transformed infrared (ATR-FTIR) spectroscopy, differential thermal analysis (DTA) and transmission electron microscopy (TEM). The oxide polymer material was compacted at 200 MPa and the expansion of this compact during heating was monitored in temperature range up to 550ºC with dilatometer. It was found that PVA forms graft polymer with PEG and specific interaction with oxide particles surface was revealed., Смеша прахова састављена од ZnO, Mn2O3 (MnCO3) и Fe2O3 комбинацијепрахова је показивала ламинацију током пресовања. Поливинил алкохол (PVA) икомбинација PVA са полиетилен гликолом (PEG) који је додат као пластификатор, сууведени као полимерно везиво за пресовање оксидних прахова. Везиво је уведено такошто је формирана суспензија смеше различитих оксида прахова у полимерномраствору. Концентрације полимера и састави су варирани. Уклањањем растварачадобијени су нови материјали који се састоје од честица оксида повезаних полимерима.Ови хибридни материјали окарактерисани су методама ометене тоталне рефлексијефурије трансформисане инфрацрвене спектроскопије (ATR-FTIR) као идиференцијалне термичке анализе (DTA). Микроструктура је посматранатрансмисоном електронском микроскопијом (TEM). Оксид-полимер материјали супресовани на притиску од 200 MPa и ширење испреска током грејања је праћено у температурском опсегу од собне до 550ºC употребом дилатометра. Нађено је да PVAформира графт полимер са PEG и да постоји специфична интеракција полимера саповршином честица оксида.",
publisher = "Belgrade : Association for ETRAN Society",
journal = "Science of Sintering",
title = "Oxide Powder Mixture with Poly-vinyl Alcohol (PVA) and added Polyethylene Glycol (PEG) as Plasticizer",
volume = "55",
pages = "189-2023",
doi = "10.2298/SOS220828005L"
}

Labus, N., Krstić, J., Matijašević, S.,& Pavlović, V.. (2023). Oxide Powder Mixture with Poly-vinyl Alcohol (PVA) and added Polyethylene Glycol (PEG) as Plasticizer. in Science of Sintering
Belgrade : Association for ETRAN Society., 55, 189-2023.
https://doi.org/10.2298/SOS220828005L

Labus N, Krstić J, Matijašević S, Pavlović V. Oxide Powder Mixture with Poly-vinyl Alcohol (PVA) and added Polyethylene Glycol (PEG) as Plasticizer. in Science of Sintering. 2023;55:189-2023.
doi:10.2298/SOS220828005L .

Labus, Nebojsa, Krstić, Jugoslav, Matijašević, Srđan, Pavlović, Vladimir, "Oxide Powder Mixture with Poly-vinyl Alcohol (PVA) and added Polyethylene Glycol (PEG) as Plasticizer" in Science of Sintering, 55 (2023):189-2023,
https://doi.org/10.2298/SOS220828005L . .

TY  - JOUR
AU  - Đukić, Dunja
AU  - Krstić, Aleksandar
AU  - Jakovljević, Ksenija
AU  - Butulija, Svetlana
AU  - Anđelković, Ljubica
AU  - Pavlović, Vladimir
AU  - Mirković, Miljana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4941
AB  - Newly designed mesoporous brushite-metakaolin-based geopolymer materials were examined with an idea for using this material as a potential adsorbent for Pb(II) removal from aqueous solutions. As a starting component for geopolymer synthesis, a natural raw kaolinite clay with the
addition of 2 wt.%, 4 wt.%, 6 wt.%, 8 wt.%, and 10 wt.% of pure brushite was used. Phase, structural,morphological, and adsorption properties of newly synthesized mesoporous brushite-metakaolin geopolymer materials were examined in detail by the means of XRPD, FTIR, SEM-EDS, BET/BJH, and ICP-OES methods. The ICP-OES results showed that the synthesized material samples with 2 wt.%, 4 wt.%, and 6 wt.% of brushite possess significant adsorption properties and the mechanisms of the adsorption process can be attributed to chemisorption. The most notable result is that brushite-metakaolin-geopolymer with 2 wt.% of brushite have the best efficiency removal, more than 85% of Pb(II).
PB  - MDPI
T2  - Sustainability
T1  - Brushite-Metakaolin Composite Geopolymer Material as an Effective Adsorbent for Lead Removal from Aqueous Solutions
VL  - 14
IS  - 7
SP  - 4003
DO  - 10.3390/su14074003
ER  - 

@article{
author = "Đukić, Dunja and Krstić, Aleksandar and Jakovljević, Ksenija and Butulija, Svetlana and Anđelković, Ljubica and Pavlović, Vladimir and Mirković, Miljana",
year = "2022",
abstract = "Newly designed mesoporous brushite-metakaolin-based geopolymer materials were examined with an idea for using this material as a potential adsorbent for Pb(II) removal from aqueous solutions. As a starting component for geopolymer synthesis, a natural raw kaolinite clay with the
addition of 2 wt.%, 4 wt.%, 6 wt.%, 8 wt.%, and 10 wt.% of pure brushite was used. Phase, structural,morphological, and adsorption properties of newly synthesized mesoporous brushite-metakaolin geopolymer materials were examined in detail by the means of XRPD, FTIR, SEM-EDS, BET/BJH, and ICP-OES methods. The ICP-OES results showed that the synthesized material samples with 2 wt.%, 4 wt.%, and 6 wt.% of brushite possess significant adsorption properties and the mechanisms of the adsorption process can be attributed to chemisorption. The most notable result is that brushite-metakaolin-geopolymer with 2 wt.% of brushite have the best efficiency removal, more than 85% of Pb(II).",
publisher = "MDPI",
journal = "Sustainability",
title = "Brushite-Metakaolin Composite Geopolymer Material as an Effective Adsorbent for Lead Removal from Aqueous Solutions",
volume = "14",
number = "7",
pages = "4003",
doi = "10.3390/su14074003"
}

Đukić, D., Krstić, A., Jakovljević, K., Butulija, S., Anđelković, L., Pavlović, V.,& Mirković, M.. (2022). Brushite-Metakaolin Composite Geopolymer Material as an Effective Adsorbent for Lead Removal from Aqueous Solutions. in Sustainability
MDPI., 14(7), 4003.
https://doi.org/10.3390/su14074003

Đukić D, Krstić A, Jakovljević K, Butulija S, Anđelković L, Pavlović V, Mirković M. Brushite-Metakaolin Composite Geopolymer Material as an Effective Adsorbent for Lead Removal from Aqueous Solutions. in Sustainability. 2022;14(7):4003.
doi:10.3390/su14074003 .

Đukić, Dunja, Krstić, Aleksandar, Jakovljević, Ksenija, Butulija, Svetlana, Anđelković, Ljubica, Pavlović, Vladimir, Mirković, Miljana, "Brushite-Metakaolin Composite Geopolymer Material as an Effective Adsorbent for Lead Removal from Aqueous Solutions" in Sustainability, 14, no. 7 (2022):4003,
https://doi.org/10.3390/su14074003 . .

TY  - JOUR
AU  - Filipović, Suzana
AU  - Obradović, Nina
AU  - Anđelković, Ljubica
AU  - Olćan, Dragan
AU  - Petrović, Jovana
AU  - Mirković, Miljana
AU  - Pavlović, Vladimir
AU  - Jeremić, Dejan
AU  - Vlahović, Branislav
AU  - Đorđević, Antonije
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4356
AB  - Solid-state reaction between BaTiO3 and Fe2O3 was used to produce a multiferroic heterostructure composite. Commercial BaTiO3 and Fe(NO3)3•9H2O were suspended in ethanol for 30 minutes in an ultrasound bath. The prepared mixture was thermally processed at 300 oC for 6 h. Sintering at 1300 oC for 1 h resulted in a mixture of different phases, BaTiO3, BaFe12O19 and Ba12Ti28Fe15O84, which were confirmed by x-ray powder diffraction. A dense microstructure with a small volume fraction of closed porosity was indicated by the scanning electron microscopy, while a homogeneous distribution of Fe ions over BaTiO3 phase was visible from energy dispersive spectroscopy mapping. Doping of BaTiO3 with Fe2O3 resulted in formation of magnetic hexaferrite phases, as confirmed by dielectric measurements that showed a broadened maximum of the permittivity measured as a function of temperature.
PB  - Belgrade : International Institute for the Science of Sintering
T2  - Science of Sintering
T1  - Multiferroic Heterostructure BaTiO3/ε-Fe2O3 Composite Obtained by in situ Reaction
VL  - 53
SP  - 1
EP  - 8
DO  - 10.2298/SOS2101001F
ER  - 

@article{
author = "Filipović, Suzana and Obradović, Nina and Anđelković, Ljubica and Olćan, Dragan and Petrović, Jovana and Mirković, Miljana and Pavlović, Vladimir and Jeremić, Dejan and Vlahović, Branislav and Đorđević, Antonije",
year = "2021",
abstract = "Solid-state reaction between BaTiO3 and Fe2O3 was used to produce a multiferroic heterostructure composite. Commercial BaTiO3 and Fe(NO3)3•9H2O were suspended in ethanol for 30 minutes in an ultrasound bath. The prepared mixture was thermally processed at 300 oC for 6 h. Sintering at 1300 oC for 1 h resulted in a mixture of different phases, BaTiO3, BaFe12O19 and Ba12Ti28Fe15O84, which were confirmed by x-ray powder diffraction. A dense microstructure with a small volume fraction of closed porosity was indicated by the scanning electron microscopy, while a homogeneous distribution of Fe ions over BaTiO3 phase was visible from energy dispersive spectroscopy mapping. Doping of BaTiO3 with Fe2O3 resulted in formation of magnetic hexaferrite phases, as confirmed by dielectric measurements that showed a broadened maximum of the permittivity measured as a function of temperature.",
publisher = "Belgrade : International Institute for the Science of Sintering",
journal = "Science of Sintering",
title = "Multiferroic Heterostructure BaTiO3/ε-Fe2O3 Composite Obtained by in situ Reaction",
volume = "53",
pages = "1-8",
doi = "10.2298/SOS2101001F"
}

Filipović, S., Obradović, N., Anđelković, L., Olćan, D., Petrović, J., Mirković, M., Pavlović, V., Jeremić, D., Vlahović, B.,& Đorđević, A.. (2021). Multiferroic Heterostructure BaTiO3/ε-Fe2O3 Composite Obtained by in situ Reaction. in Science of Sintering
Belgrade : International Institute for the Science of Sintering., 53, 1-8.
https://doi.org/10.2298/SOS2101001F

Filipović S, Obradović N, Anđelković L, Olćan D, Petrović J, Mirković M, Pavlović V, Jeremić D, Vlahović B, Đorđević A. Multiferroic Heterostructure BaTiO3/ε-Fe2O3 Composite Obtained by in situ Reaction. in Science of Sintering. 2021;53:1-8.
doi:10.2298/SOS2101001F .

Filipović, Suzana, Obradović, Nina, Anđelković, Ljubica, Olćan, Dragan, Petrović, Jovana, Mirković, Miljana, Pavlović, Vladimir, Jeremić, Dejan, Vlahović, Branislav, Đorđević, Antonije, "Multiferroic Heterostructure BaTiO3/ε-Fe2O3 Composite Obtained by in situ Reaction" in Science of Sintering, 53 (2021):1-8,
https://doi.org/10.2298/SOS2101001F . .

TY  - CONF
AU  - Popović, Mina
AU  - Marinković, Aleksandar
AU  - Pavlović, Vladimir
AU  - Ljubić, Verica
AU  - Veličković, Zlate
AU  - Perendija, Jovana
AU  - Vasiljević, Ljubica
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7088
AB  - The very serious problem in developing countries has become the presence of the arsenic
contamination in the water for the public health. Still, millions of people in their daily lives are
highly dependent on groundwater containing high levels of arsenic, as well as, in drinking water,
which causes excessive exposure to this toxic element, due to the high cost and lack of watertreatment infrastructures. The maximal allowed concentration (MAC) for As(V) in water
decreased from 50 to 10 μg/l, by considering the harmful effects of arsenic on the environment
and human health. In order to achieve the established rigorous requirements, it is necessary to
develop new materials and design new forms of adsorbents that can reduce the concentration of
arsenic in drinking water. Therefore, in this study, the target was to synthesize magnetite/3Dprinted wollastonite hybrid sorbent that was used to remove As(V) from aqueous solutions. 3Dprinted wollastonite was obtained using the 3D-printing technique from
methylhydrocyclosiloxane and calcium carbonate as precursors. Synthesis of adsorption
material was carried out by depositing magnetite from an iron(II)-sulfate solution by potassium
hydroxide on 3D-printed wollastonite. Characterization of the obtained material was performed
using FTIR and SEM. An investigation of the sorption properties of hybrid adsorbents was
carried out for As(V) removal - one relative to the starting pH value of the solution, the
adsorbent mass and the temperature and the adsorption time. Determination of adsorption
parameters was performed by applying Langmuir, Freundlich and Dubinin-Radushkevich
equations. Determination of kinetics and adhesion parameters at three different temperatures
enabled the calculation of thermodynamic and activation parameters of the adsorption process,
which contributed to a better understanding of the adsorption mechanism. Also, based on the
results, it was noticed that the highest adsorption capacity of the mentioned material for arsenic
ions at a temperature of 45 °C. The compact filter presented in this report should serve well as a
small-scale water-purification unit that can be easily carried to any site having water
contaminated with arsenic
PB  - Zvornik : Faculty of Technology
C3  - Book of Abstracts - VII International Congress “Engineering, Environment and Materials in Process Industry“, March 17-19 2021, Jahorina, Republic of Srpska, Bosnia and Herzegovina
T1  - Removal of the As(V) from the water using magnetite/3D-printed wollastonite hybrid sorbent
SP  - 186
EP  - 186
UR  - https://hdl.handle.net/21.15107/rcub_cer_7088
ER  - 

@conference{
author = "Popović, Mina and Marinković, Aleksandar and Pavlović, Vladimir and Ljubić, Verica and Veličković, Zlate and Perendija, Jovana and Vasiljević, Ljubica",
year = "2021",
abstract = "The very serious problem in developing countries has become the presence of the arsenic
contamination in the water for the public health. Still, millions of people in their daily lives are
highly dependent on groundwater containing high levels of arsenic, as well as, in drinking water,
which causes excessive exposure to this toxic element, due to the high cost and lack of watertreatment infrastructures. The maximal allowed concentration (MAC) for As(V) in water
decreased from 50 to 10 μg/l, by considering the harmful effects of arsenic on the environment
and human health. In order to achieve the established rigorous requirements, it is necessary to
develop new materials and design new forms of adsorbents that can reduce the concentration of
arsenic in drinking water. Therefore, in this study, the target was to synthesize magnetite/3Dprinted wollastonite hybrid sorbent that was used to remove As(V) from aqueous solutions. 3Dprinted wollastonite was obtained using the 3D-printing technique from
methylhydrocyclosiloxane and calcium carbonate as precursors. Synthesis of adsorption
material was carried out by depositing magnetite from an iron(II)-sulfate solution by potassium
hydroxide on 3D-printed wollastonite. Characterization of the obtained material was performed
using FTIR and SEM. An investigation of the sorption properties of hybrid adsorbents was
carried out for As(V) removal - one relative to the starting pH value of the solution, the
adsorbent mass and the temperature and the adsorption time. Determination of adsorption
parameters was performed by applying Langmuir, Freundlich and Dubinin-Radushkevich
equations. Determination of kinetics and adhesion parameters at three different temperatures
enabled the calculation of thermodynamic and activation parameters of the adsorption process,
which contributed to a better understanding of the adsorption mechanism. Also, based on the
results, it was noticed that the highest adsorption capacity of the mentioned material for arsenic
ions at a temperature of 45 °C. The compact filter presented in this report should serve well as a
small-scale water-purification unit that can be easily carried to any site having water
contaminated with arsenic",
publisher = "Zvornik : Faculty of Technology",
journal = "Book of Abstracts - VII International Congress “Engineering, Environment and Materials in Process Industry“, March 17-19 2021, Jahorina, Republic of Srpska, Bosnia and Herzegovina",
title = "Removal of the As(V) from the water using magnetite/3D-printed wollastonite hybrid sorbent",
pages = "186-186",
url = "https://hdl.handle.net/21.15107/rcub_cer_7088"
}

Popović, M., Marinković, A., Pavlović, V., Ljubić, V., Veličković, Z., Perendija, J.,& Vasiljević, L.. (2021). Removal of the As(V) from the water using magnetite/3D-printed wollastonite hybrid sorbent. in Book of Abstracts - VII International Congress “Engineering, Environment and Materials in Process Industry“, March 17-19 2021, Jahorina, Republic of Srpska, Bosnia and Herzegovina
Zvornik : Faculty of Technology., 186-186.
https://hdl.handle.net/21.15107/rcub_cer_7088

Popović M, Marinković A, Pavlović V, Ljubić V, Veličković Z, Perendija J, Vasiljević L. Removal of the As(V) from the water using magnetite/3D-printed wollastonite hybrid sorbent. in Book of Abstracts - VII International Congress “Engineering, Environment and Materials in Process Industry“, March 17-19 2021, Jahorina, Republic of Srpska, Bosnia and Herzegovina. 2021;:186-186.
https://hdl.handle.net/21.15107/rcub_cer_7088 .

Popović, Mina, Marinković, Aleksandar, Pavlović, Vladimir, Ljubić, Verica, Veličković, Zlate, Perendija, Jovana, Vasiljević, Ljubica, "Removal of the As(V) from the water using magnetite/3D-printed wollastonite hybrid sorbent" in Book of Abstracts - VII International Congress “Engineering, Environment and Materials in Process Industry“, March 17-19 2021, Jahorina, Republic of Srpska, Bosnia and Herzegovina (2021):186-186,
https://hdl.handle.net/21.15107/rcub_cer_7088 .

TY  - CONF
AU  - Stefanović, Ivan
AU  - Stefanov, Plamen
AU  - Pavlović, Vladimir
AU  - Pergal, Marija
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5739
AB  - Series of poly(urethane-siloxane) nanocomposites (PUSN) was synthesized based on 4,4'-methylenediphenyldiisocyanate and 1,4-butanediol as the comonomers of the hard segments and 
poly(propyleneoxide)-b-poly(dimethylsiloxane)-b-poly(propyleneoxide) as the part of the soft 
segments. The effect of the addition of nanoparticles of organomodified clay (Cloisite 30B*) on 
thermal, mechanical, surface and morphological properties of these PUSNs was investigated. 
TGA analysis confirmed that the addition of clay nanoparticles in the amount of only 1 wt. % 
leads to an improvement C. Modulus of elasticity and tensile strength were also increased after the reinforcement of poly(urethane-siloxane) matrix with clay nanoparticles. XPS analysis confirmed the presence of a large quantity of Si atomon the surface of the films, which is why these PUSNs exhibit extremely high surface hydrophobicity. TEM analysis revealed homogeneous dispersion of clay nanoparticles and existance of mixed intercalary-exfoliated morphology within the structure of PUSNs.
PB  - Serbian Chemical Society
C3  - Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia
T1  - Effects of organically modified clay nanoparticles on the properties of poly(urethane-siloxane) nanocomposites
T1  - Uticaj organski modifikovanih naničestica gline na svojstva  poli(uretan-siloksanskih) nanokompozita
SP  - 12
EP  - 12
UR  - https://hdl.handle.net/21.15107/rcub_cer_5739
ER  - 

@conference{
author = "Stefanović, Ivan and Stefanov, Plamen and Pavlović, Vladimir and Pergal, Marija",
year = "2016",
abstract = "Series of poly(urethane-siloxane) nanocomposites (PUSN) was synthesized based on 4,4'-methylenediphenyldiisocyanate and 1,4-butanediol as the comonomers of the hard segments and 
poly(propyleneoxide)-b-poly(dimethylsiloxane)-b-poly(propyleneoxide) as the part of the soft 
segments. The effect of the addition of nanoparticles of organomodified clay (Cloisite 30B*) on 
thermal, mechanical, surface and morphological properties of these PUSNs was investigated. 
TGA analysis confirmed that the addition of clay nanoparticles in the amount of only 1 wt. % 
leads to an improvement C. Modulus of elasticity and tensile strength were also increased after the reinforcement of poly(urethane-siloxane) matrix with clay nanoparticles. XPS analysis confirmed the presence of a large quantity of Si atomon the surface of the films, which is why these PUSNs exhibit extremely high surface hydrophobicity. TEM analysis revealed homogeneous dispersion of clay nanoparticles and existance of mixed intercalary-exfoliated morphology within the structure of PUSNs.",
publisher = "Serbian Chemical Society",
journal = "Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia",
title = "Effects of organically modified clay nanoparticles on the properties of poly(urethane-siloxane) nanocomposites, Uticaj organski modifikovanih naničestica gline na svojstva  poli(uretan-siloksanskih) nanokompozita",
pages = "12-12",
url = "https://hdl.handle.net/21.15107/rcub_cer_5739"
}

Stefanović, I., Stefanov, P., Pavlović, V.,& Pergal, M.. (2016). Effects of organically modified clay nanoparticles on the properties of poly(urethane-siloxane) nanocomposites. in Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia
Serbian Chemical Society., 12-12.
https://hdl.handle.net/21.15107/rcub_cer_5739

Stefanović I, Stefanov P, Pavlović V, Pergal M. Effects of organically modified clay nanoparticles on the properties of poly(urethane-siloxane) nanocomposites. in Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia. 2016;:12-12.
https://hdl.handle.net/21.15107/rcub_cer_5739 .

Stefanović, Ivan, Stefanov, Plamen, Pavlović, Vladimir, Pergal, Marija, "Effects of organically modified clay nanoparticles on the properties of poly(urethane-siloxane) nanocomposites" in Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia (2016):12-12,
https://hdl.handle.net/21.15107/rcub_cer_5739 .

TY  - JOUR
AU  - Krstić, Natalija
AU  - Pavlović, Vladimir D.
AU  - Novaković, Irena
AU  - Matić, Ivana Z.
AU  - Sladić, Dušan
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1200
AB  - The reactions of 21-hydroxyprogesterone with Lawesson's reagent in toluene or gave four P-heterocyclic androst-4-ene derivatives (two tautomeric pairs): 4-(3-thioxoandrost-4-en-17-yl)-1,3,2-oxathiaphosphole-2- sulfide (2), 4-(3-thioxoandrost-4-en-17-ylidene)-1,3,2-oxathiaphospholane-2-sulfide (3), 4-(3-oxoandrost-4-en-17-yl)-1,3,2-oxathiaphosphole-2-sulfide (4), and 4-(3-oxoandrost-4-en-17-ylidene)-1,3,2- oxathiaphospholane-2-sulfide (5). The structures of all novel 17-substituted steroids were elucidated from their analytic and spectral data (HRMS, IR, 1D NMR and 2D NMR-HSQC, HMBC, NOESY, COSY). The detailed NMR analysis for all compounds revealed the presence of two pairs of signals in approx. 8:2 ratio indicating the existence of two diastereoisomers (a and b) with different configurations at the phosphorus atom. A parallel analysis of heteronuclear 2D - spectra (HSQC and HMBC) and homonuclear 2D spectra (NOESY and COSY) enabled complete and assignments of each isomer and provided evidence for the preferred configuration on phosphorus atom. Cytotoxic activity in vitro was tested against four tumor cell lines (human cervix carcinoma HeLa cells, chronic myelogenous leukemia K-562 and two human breast carcinoma MDA-MB-361 and MDA-MB-453 cells). Compounds 3a,b and 4a,b showed a poor activity against HeLa and MDA-MB-453 cell lines, while against MDA-MB-361 cell line, all tested compounds exerted very weak cytotoxic effect. All compounds exerted moderate activity against K562 cells. Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungal cells, and toxicity to brine shrimp Artemia salina were evaluated. All tested compounds showed strong antifungal activity.
PB  - Springer, Dordrecht
T2  - Molecular Diversity
T1  - Synthesis, characterization and biological evaluation of some novel P-heterocyclic androst-4-ene derivatives
VL  - 17
IS  - 3
SP  - 547
EP  - 561
DO  - 10.1007/s11030-013-9455-9
ER  - 

@article{
author = "Krstić, Natalija and Pavlović, Vladimir D. and Novaković, Irena and Matić, Ivana Z. and Sladić, Dušan",
year = "2013",
abstract = "The reactions of 21-hydroxyprogesterone with Lawesson's reagent in toluene or gave four P-heterocyclic androst-4-ene derivatives (two tautomeric pairs): 4-(3-thioxoandrost-4-en-17-yl)-1,3,2-oxathiaphosphole-2- sulfide (2), 4-(3-thioxoandrost-4-en-17-ylidene)-1,3,2-oxathiaphospholane-2-sulfide (3), 4-(3-oxoandrost-4-en-17-yl)-1,3,2-oxathiaphosphole-2-sulfide (4), and 4-(3-oxoandrost-4-en-17-ylidene)-1,3,2- oxathiaphospholane-2-sulfide (5). The structures of all novel 17-substituted steroids were elucidated from their analytic and spectral data (HRMS, IR, 1D NMR and 2D NMR-HSQC, HMBC, NOESY, COSY). The detailed NMR analysis for all compounds revealed the presence of two pairs of signals in approx. 8:2 ratio indicating the existence of two diastereoisomers (a and b) with different configurations at the phosphorus atom. A parallel analysis of heteronuclear 2D - spectra (HSQC and HMBC) and homonuclear 2D spectra (NOESY and COSY) enabled complete and assignments of each isomer and provided evidence for the preferred configuration on phosphorus atom. Cytotoxic activity in vitro was tested against four tumor cell lines (human cervix carcinoma HeLa cells, chronic myelogenous leukemia K-562 and two human breast carcinoma MDA-MB-361 and MDA-MB-453 cells). Compounds 3a,b and 4a,b showed a poor activity against HeLa and MDA-MB-453 cell lines, while against MDA-MB-361 cell line, all tested compounds exerted very weak cytotoxic effect. All compounds exerted moderate activity against K562 cells. Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungal cells, and toxicity to brine shrimp Artemia salina were evaluated. All tested compounds showed strong antifungal activity.",
publisher = "Springer, Dordrecht",
journal = "Molecular Diversity",
title = "Synthesis, characterization and biological evaluation of some novel P-heterocyclic androst-4-ene derivatives",
volume = "17",
number = "3",
pages = "547-561",
doi = "10.1007/s11030-013-9455-9"
}

Krstić, N., Pavlović, V. D., Novaković, I., Matić, I. Z.,& Sladić, D.. (2013). Synthesis, characterization and biological evaluation of some novel P-heterocyclic androst-4-ene derivatives. in Molecular Diversity
Springer, Dordrecht., 17(3), 547-561.
https://doi.org/10.1007/s11030-013-9455-9

Krstić N, Pavlović VD, Novaković I, Matić IZ, Sladić D. Synthesis, characterization and biological evaluation of some novel P-heterocyclic androst-4-ene derivatives. in Molecular Diversity. 2013;17(3):547-561.
doi:10.1007/s11030-013-9455-9 .

Krstić, Natalija, Pavlović, Vladimir D., Novaković, Irena, Matić, Ivana Z., Sladić, Dušan, "Synthesis, characterization and biological evaluation of some novel P-heterocyclic androst-4-ene derivatives" in Molecular Diversity, 17, no. 3 (2013):547-561,
https://doi.org/10.1007/s11030-013-9455-9 . .

TY  - JOUR
AU  - Krstić, Natalija
AU  - Bjelaković, Mira
AU  - Pavlović, Vladimir D.
AU  - Robeyns, Koen
AU  - Juranić, Zorica
AU  - Matić, Ivana Z.
AU  - Novaković, Irena
AU  - Sladić, Dušan
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/945
AB  - The reactions of 17 alpha-hydroxyprogesterone with Lawesson's reagent (LR) in toluene, CH2Cl2 and/or CCl4 gave, depending on the duration of the reaction, two diastereoisomeric androst-4-en-17-spiro-1,3,2-oxathiaphospholane-2-sulfide pairs 2a,b and 3a,b in approximately 7:3 ratio, differing in configuration at the phosphorus atom. A parallel analysis of heteronuclear 2D H-1-C-13 spectra (HSQC and HMBC) and homo-nuclear 2D spectra (NOESY) enabled complete H-1 and C-13 assignments of each isomer. Also, analysis of NOESY correlations provided evidence for the preferred conformation. X-ray analysis of 3a confirmed the structure and absolute configuration on phosphorus. A pathway for the formation of 1,3,2-oxathiaphospholane ring was proposed. Cytotoxic activity in vitro was tested against three tumor cell lines (human cervix carcinoma HeLa cells and two human breast carcinoma MDA-MB-361 and MDA-MB-453 cells). Compound 3a and mixture 3a,b showed a moderate activity against HeLa and MDA-MB-453 cell lines while against MDA-MB-361 cell line all tested compounds exerted very weak cytotoxic effect. Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungal cells, toxicity to brine shrimp Artemia sauna, were evaluated. All tested compounds showed strong antifungal activity.
PB  - Elsevier Science Inc, New York
T2  - Steroids
T1  - New androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. Synthesis, assignment of absolute configuration and in vitro cytotoxic and antimicrobial activities
VL  - 77
IS  - 5
SP  - 558
EP  - 565
DO  - 10.1016/j.steroids.2012.01.021
ER  - 

@article{
author = "Krstić, Natalija and Bjelaković, Mira and Pavlović, Vladimir D. and Robeyns, Koen and Juranić, Zorica and Matić, Ivana Z. and Novaković, Irena and Sladić, Dušan",
year = "2012",
abstract = "The reactions of 17 alpha-hydroxyprogesterone with Lawesson's reagent (LR) in toluene, CH2Cl2 and/or CCl4 gave, depending on the duration of the reaction, two diastereoisomeric androst-4-en-17-spiro-1,3,2-oxathiaphospholane-2-sulfide pairs 2a,b and 3a,b in approximately 7:3 ratio, differing in configuration at the phosphorus atom. A parallel analysis of heteronuclear 2D H-1-C-13 spectra (HSQC and HMBC) and homo-nuclear 2D spectra (NOESY) enabled complete H-1 and C-13 assignments of each isomer. Also, analysis of NOESY correlations provided evidence for the preferred conformation. X-ray analysis of 3a confirmed the structure and absolute configuration on phosphorus. A pathway for the formation of 1,3,2-oxathiaphospholane ring was proposed. Cytotoxic activity in vitro was tested against three tumor cell lines (human cervix carcinoma HeLa cells and two human breast carcinoma MDA-MB-361 and MDA-MB-453 cells). Compound 3a and mixture 3a,b showed a moderate activity against HeLa and MDA-MB-453 cell lines while against MDA-MB-361 cell line all tested compounds exerted very weak cytotoxic effect. Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungal cells, toxicity to brine shrimp Artemia sauna, were evaluated. All tested compounds showed strong antifungal activity.",
publisher = "Elsevier Science Inc, New York",
journal = "Steroids",
title = "New androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. Synthesis, assignment of absolute configuration and in vitro cytotoxic and antimicrobial activities",
volume = "77",
number = "5",
pages = "558-565",
doi = "10.1016/j.steroids.2012.01.021"
}

Krstić, N., Bjelaković, M., Pavlović, V. D., Robeyns, K., Juranić, Z., Matić, I. Z., Novaković, I.,& Sladić, D.. (2012). New androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. Synthesis, assignment of absolute configuration and in vitro cytotoxic and antimicrobial activities. in Steroids
Elsevier Science Inc, New York., 77(5), 558-565.
https://doi.org/10.1016/j.steroids.2012.01.021

Krstić N, Bjelaković M, Pavlović VD, Robeyns K, Juranić Z, Matić IZ, Novaković I, Sladić D. New androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. Synthesis, assignment of absolute configuration and in vitro cytotoxic and antimicrobial activities. in Steroids. 2012;77(5):558-565.
doi:10.1016/j.steroids.2012.01.021 .

Krstić, Natalija, Bjelaković, Mira, Pavlović, Vladimir D., Robeyns, Koen, Juranić, Zorica, Matić, Ivana Z., Novaković, Irena, Sladić, Dušan, "New androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. Synthesis, assignment of absolute configuration and in vitro cytotoxic and antimicrobial activities" in Steroids, 77, no. 5 (2012):558-565,
https://doi.org/10.1016/j.steroids.2012.01.021 . .

TY  - JOUR
AU  - Bjelaković, Mira
AU  - Krstić, Natalija
AU  - Milić, Dragana
AU  - Kop, Tatjana
AU  - Robeyns, Koen
AU  - Pavlović, Vladimir D.
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1114
AB  - The present study is concerned with the oxidative behaviour of unsaturated and epoxy 5-oxo-5,10-secosteroids in the presence of m-CPBA or TFAA-UHP as oxidants in order to investigate potential parameters controlling the chemoselectivity and regioselectivity. In the study we discovered a striking difference in the chemical behaviour of stereoisomeric compounds, (Z)- and (E)-3 beta-acetoxy-5,10-secocholest-1(10)-en-5-ones, as well as 1S,10R- and 1R,10R-epoxides. The secoketones were oxidized with exclusively C-6 migration and Baeyer-Villiger rearrangement product formation, whereas their stereoisomers provided the ring-contracted products, without lactone formation. The preferred conformation of expanded and contracted rings was established by NOESY correlations. The structures of two obtained lactones were also confirmed by X-ray analysis. The mechanistic and stereochemical aspects of these transformations are discussed.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Tetrahedron
T1  - Oxidative 10-membered ring expansion and contraction of stereoisomeric 1(10)-unsaturated and 1,10-epoxy-5-oxo-5,10-secosteroids induced by peracids
VL  - 68
IS  - 36
SP  - 7479
EP  - 7488
DO  - 10.1016/j.tet.2012.06.024
ER  - 

@article{
author = "Bjelaković, Mira and Krstić, Natalija and Milić, Dragana and Kop, Tatjana and Robeyns, Koen and Pavlović, Vladimir D.",
year = "2012",
abstract = "The present study is concerned with the oxidative behaviour of unsaturated and epoxy 5-oxo-5,10-secosteroids in the presence of m-CPBA or TFAA-UHP as oxidants in order to investigate potential parameters controlling the chemoselectivity and regioselectivity. In the study we discovered a striking difference in the chemical behaviour of stereoisomeric compounds, (Z)- and (E)-3 beta-acetoxy-5,10-secocholest-1(10)-en-5-ones, as well as 1S,10R- and 1R,10R-epoxides. The secoketones were oxidized with exclusively C-6 migration and Baeyer-Villiger rearrangement product formation, whereas their stereoisomers provided the ring-contracted products, without lactone formation. The preferred conformation of expanded and contracted rings was established by NOESY correlations. The structures of two obtained lactones were also confirmed by X-ray analysis. The mechanistic and stereochemical aspects of these transformations are discussed.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Tetrahedron",
title = "Oxidative 10-membered ring expansion and contraction of stereoisomeric 1(10)-unsaturated and 1,10-epoxy-5-oxo-5,10-secosteroids induced by peracids",
volume = "68",
number = "36",
pages = "7479-7488",
doi = "10.1016/j.tet.2012.06.024"
}

Bjelaković, M., Krstić, N., Milić, D., Kop, T., Robeyns, K.,& Pavlović, V. D.. (2012). Oxidative 10-membered ring expansion and contraction of stereoisomeric 1(10)-unsaturated and 1,10-epoxy-5-oxo-5,10-secosteroids induced by peracids. in Tetrahedron
Oxford : Pergamon-Elsevier Science Ltd., 68(36), 7479-7488.
https://doi.org/10.1016/j.tet.2012.06.024

Bjelaković M, Krstić N, Milić D, Kop T, Robeyns K, Pavlović VD. Oxidative 10-membered ring expansion and contraction of stereoisomeric 1(10)-unsaturated and 1,10-epoxy-5-oxo-5,10-secosteroids induced by peracids. in Tetrahedron. 2012;68(36):7479-7488.
doi:10.1016/j.tet.2012.06.024 .

Bjelaković, Mira, Krstić, Natalija, Milić, Dragana, Kop, Tatjana, Robeyns, Koen, Pavlović, Vladimir D., "Oxidative 10-membered ring expansion and contraction of stereoisomeric 1(10)-unsaturated and 1,10-epoxy-5-oxo-5,10-secosteroids induced by peracids" in Tetrahedron, 68, no. 36 (2012):7479-7488,
https://doi.org/10.1016/j.tet.2012.06.024 . .

TY  - JOUR
AU  - Krstić, Natalija
AU  - Bjelaković, Mira
AU  - Dabović, Milan
AU  - Pavlović, Vladimir D.
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/629
AB  - The reactions of selected alpha,beta-unsaturated steroidal ketones with Lawesson's reagent (LR) in CH(2)Cl(2) and toluene under the standard reaction conditions and with a combination of phosphorus pentasulfide with hexamethyldisiloxane (P(4)S(10)/HMDO) in 1,2-dichlorobenzene (ODCB) under microwave irradiation were investigated and for this purpose several cholestane, androstane and pregnane carbonyl derivatives were chosen. Depending on the reagent and the solvent, 19 new sulfur containing compounds, including dithiones 4c and 4d, alpha,beta-unsaturated 3-thiones 3a-e, dimer-sulfides 2a-e, 1,2,4-trithiolanes 5a-e and phosphonotrithioates 6b-e were synthesized. All newly prepared compounds were characterized by IR, (1)H- and (13)C-NMR spectroscopy and elemental analysis.
PB  - MDPI
T2  - Molecules
T1  - Thionation of Some alpha,beta-Unsaturated Steroidal Ketones
VL  - 15
IS  - 5
SP  - 3462
EP  - 3477
DO  - 10.3390/molecules15053462
ER  - 

@article{
author = "Krstić, Natalija and Bjelaković, Mira and Dabović, Milan and Pavlović, Vladimir D.",
year = "2010",
abstract = "The reactions of selected alpha,beta-unsaturated steroidal ketones with Lawesson's reagent (LR) in CH(2)Cl(2) and toluene under the standard reaction conditions and with a combination of phosphorus pentasulfide with hexamethyldisiloxane (P(4)S(10)/HMDO) in 1,2-dichlorobenzene (ODCB) under microwave irradiation were investigated and for this purpose several cholestane, androstane and pregnane carbonyl derivatives were chosen. Depending on the reagent and the solvent, 19 new sulfur containing compounds, including dithiones 4c and 4d, alpha,beta-unsaturated 3-thiones 3a-e, dimer-sulfides 2a-e, 1,2,4-trithiolanes 5a-e and phosphonotrithioates 6b-e were synthesized. All newly prepared compounds were characterized by IR, (1)H- and (13)C-NMR spectroscopy and elemental analysis.",
publisher = "MDPI",
journal = "Molecules",
title = "Thionation of Some alpha,beta-Unsaturated Steroidal Ketones",
volume = "15",
number = "5",
pages = "3462-3477",
doi = "10.3390/molecules15053462"
}

Krstić, N., Bjelaković, M., Dabović, M.,& Pavlović, V. D.. (2010). Thionation of Some alpha,beta-Unsaturated Steroidal Ketones. in Molecules
MDPI., 15(5), 3462-3477.
https://doi.org/10.3390/molecules15053462

Krstić N, Bjelaković M, Dabović M, Pavlović VD. Thionation of Some alpha,beta-Unsaturated Steroidal Ketones. in Molecules. 2010;15(5):3462-3477.
doi:10.3390/molecules15053462 .

Krstić, Natalija, Bjelaković, Mira, Dabović, Milan, Pavlović, Vladimir D., "Thionation of Some alpha,beta-Unsaturated Steroidal Ketones" in Molecules, 15, no. 5 (2010):3462-3477,
https://doi.org/10.3390/molecules15053462 . .

TY  - JOUR
AU  - Bjelaković, Mira
AU  - Krstić, Natalija
AU  - Todorović, Nina
AU  - Krunić, Aleksej
AU  - Tinant, Bernard
AU  - Dabović, Milan
AU  - Pavlović, Vladimir D.
PY  - 2009
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/620
AB  - In this paper a synthetic pathway to the modified 5,10:13,14-bisfragmentation cholestane derivatives 8-14 is described. The synthesis involves introduction of the 5α- and 14α-hydroxyl groups in the cholestane molecule and subsequent cleavage of the C(5)-C(10) bond in 5α,14α-dihydroxycholestan-3β-yl acetate (4) with the HgO/I2 reagent and the C(13)-C(14) bond in the stereoisomeric 14α-hydroxy-5,10-secosteroids 5 and 6 with the Pb(OAc)4/I2 reagent. Complete and unambiguous 1H and 13C NMR resonance assignments of the obtained secosteroids, as well as the solution conformations of their 10- and 9-membered rings were determined by extensive analysis of 1D and 2D NMR spectral data. The structures and the solid-state conformations of 5,10-secosteroids 5-7 were confirmed by X-ray analysis. All diseco-compounds have a novel 5,10:13,14-disecocholestane skeleton.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Tetrahedron
T1  - 5,10:13,14-Disecosteroids: novel modified steroids containing 10- and 9-membered rings
VL  - 65
IS  - 46
SP  - 9557
EP  - 9568
DO  - 10.1016/j.tet.2009.09.066
ER  - 

@article{
author = "Bjelaković, Mira and Krstić, Natalija and Todorović, Nina and Krunić, Aleksej and Tinant, Bernard and Dabović, Milan and Pavlović, Vladimir D.",
year = "2009",
abstract = "In this paper a synthetic pathway to the modified 5,10:13,14-bisfragmentation cholestane derivatives 8-14 is described. The synthesis involves introduction of the 5α- and 14α-hydroxyl groups in the cholestane molecule and subsequent cleavage of the C(5)-C(10) bond in 5α,14α-dihydroxycholestan-3β-yl acetate (4) with the HgO/I2 reagent and the C(13)-C(14) bond in the stereoisomeric 14α-hydroxy-5,10-secosteroids 5 and 6 with the Pb(OAc)4/I2 reagent. Complete and unambiguous 1H and 13C NMR resonance assignments of the obtained secosteroids, as well as the solution conformations of their 10- and 9-membered rings were determined by extensive analysis of 1D and 2D NMR spectral data. The structures and the solid-state conformations of 5,10-secosteroids 5-7 were confirmed by X-ray analysis. All diseco-compounds have a novel 5,10:13,14-disecocholestane skeleton.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Tetrahedron",
title = "5,10:13,14-Disecosteroids: novel modified steroids containing 10- and 9-membered rings",
volume = "65",
number = "46",
pages = "9557-9568",
doi = "10.1016/j.tet.2009.09.066"
}

Bjelaković, M., Krstić, N., Todorović, N., Krunić, A., Tinant, B., Dabović, M.,& Pavlović, V. D.. (2009). 5,10:13,14-Disecosteroids: novel modified steroids containing 10- and 9-membered rings. in Tetrahedron
Oxford : Pergamon-Elsevier Science Ltd., 65(46), 9557-9568.
https://doi.org/10.1016/j.tet.2009.09.066

Bjelaković M, Krstić N, Todorović N, Krunić A, Tinant B, Dabović M, Pavlović VD. 5,10:13,14-Disecosteroids: novel modified steroids containing 10- and 9-membered rings. in Tetrahedron. 2009;65(46):9557-9568.
doi:10.1016/j.tet.2009.09.066 .

Bjelaković, Mira, Krstić, Natalija, Todorović, Nina, Krunić, Aleksej, Tinant, Bernard, Dabović, Milan, Pavlović, Vladimir D., "5,10:13,14-Disecosteroids: novel modified steroids containing 10- and 9-membered rings" in Tetrahedron, 65, no. 46 (2009):9557-9568,
https://doi.org/10.1016/j.tet.2009.09.066 . .

TY  - JOUR
AU  - Krstić, Natalija
AU  - Bjelaković, Mira
AU  - Žižak, Željko
AU  - Pavlović, Mirjana
AU  - Juranić, Zorica
AU  - Pavlović, Vladimir D.
PY  - 2007
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/363
AB  - The antiproliferative activity of previously synthesized (Z)-cholest-4-en-6-one oxime (1), (E)-cholest-4-en-6-one oxime (2), 7-aza-B-homocholest-4-en-6-one (3) and 6-aza-B-homocholest-4-en-7-one (4) and newly synthesized 6-thioxo-7-aza-B-homocholest-4-ene (5) and 6-aza-7-thioxo-B-homocholest-4-ene (6) was tested for their possible effects against two human tumor cell lines, cervical carcinoma (HeLa) and chronic myelogenous leukemia (K-562). Compounds 1-6, exerted a dose-dependent antiproliferative effect toward cell lines used in experimental design, showing high selectivity in their action for tumor cells in comparison to normal immunocompetent cells (non-stimulated PBMC and PHA-stimulated PBMC). Compounds 2, 3 and 4 exhibited a very high but selective antitumor activity, by inducing apoptosis in sensitive, for that purpose targeted tumor cell line (HeLa cells). Low toxic effect upon both non-stimulated, and PHA stimulated PBMCs from control, healthy volunteers, has been detected for compounds 1, 2, 3 and 4. The possible reasons for profound differences in the effects of this spectrum of steroidal compounds between tumor cell lines and normal stimulated and non-stimulated PBMCs are discussed. The molecular mechanisms for apoptotic events in HeLa cell line are suggested. The guidelines for further research are underlined.
PB  - Elsevier
T2  - Steroids
T1  - Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities
VL  - 72
IS  - 5
SP  - 406
EP  - 414
DO  - 10.1016/j.steroids.2007.02.005
ER  - 

@article{
author = "Krstić, Natalija and Bjelaković, Mira and Žižak, Željko and Pavlović, Mirjana and Juranić, Zorica and Pavlović, Vladimir D.",
year = "2007",
abstract = "The antiproliferative activity of previously synthesized (Z)-cholest-4-en-6-one oxime (1), (E)-cholest-4-en-6-one oxime (2), 7-aza-B-homocholest-4-en-6-one (3) and 6-aza-B-homocholest-4-en-7-one (4) and newly synthesized 6-thioxo-7-aza-B-homocholest-4-ene (5) and 6-aza-7-thioxo-B-homocholest-4-ene (6) was tested for their possible effects against two human tumor cell lines, cervical carcinoma (HeLa) and chronic myelogenous leukemia (K-562). Compounds 1-6, exerted a dose-dependent antiproliferative effect toward cell lines used in experimental design, showing high selectivity in their action for tumor cells in comparison to normal immunocompetent cells (non-stimulated PBMC and PHA-stimulated PBMC). Compounds 2, 3 and 4 exhibited a very high but selective antitumor activity, by inducing apoptosis in sensitive, for that purpose targeted tumor cell line (HeLa cells). Low toxic effect upon both non-stimulated, and PHA stimulated PBMCs from control, healthy volunteers, has been detected for compounds 1, 2, 3 and 4. The possible reasons for profound differences in the effects of this spectrum of steroidal compounds between tumor cell lines and normal stimulated and non-stimulated PBMCs are discussed. The molecular mechanisms for apoptotic events in HeLa cell line are suggested. The guidelines for further research are underlined.",
publisher = "Elsevier",
journal = "Steroids",
title = "Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities",
volume = "72",
number = "5",
pages = "406-414",
doi = "10.1016/j.steroids.2007.02.005"
}

Krstić, N., Bjelaković, M., Žižak, Ž., Pavlović, M., Juranić, Z.,& Pavlović, V. D.. (2007). Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities. in Steroids
Elsevier., 72(5), 406-414.
https://doi.org/10.1016/j.steroids.2007.02.005

Krstić N, Bjelaković M, Žižak Ž, Pavlović M, Juranić Z, Pavlović VD. Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities. in Steroids. 2007;72(5):406-414.
doi:10.1016/j.steroids.2007.02.005 .

Krstić, Natalija, Bjelaković, Mira, Žižak, Željko, Pavlović, Mirjana, Juranić, Zorica, Pavlović, Vladimir D., "Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities" in Steroids, 72, no. 5 (2007):406-414,
https://doi.org/10.1016/j.steroids.2007.02.005 . .

TY  - JOUR
AU  - Bjelaković, Mira
AU  - Krstić, Natalija
AU  - Juranić, Nenad
AU  - Dabović, Milan
AU  - Gojković, S.V.
AU  - Kessler, M.
AU  - Kalvoda, J.
AU  - Pavlović, Vladimir D.
PY  - 2007
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/358
AB  - We report herein the synthesis of a novel modified steroid with two rigidly positioned amino acids in C- and N-protected forms (Gly-OtBu and N-Fmoc-l-Phe) at the angular positions (C-18 methylamino group and C-19 carboxylic function) of the steroid nucleus via amide bonds, starting from 18-cyanopregnenolone acetate over 10 steps. In an attempt to gain more insight into the structural and conformational features of this novel 18-Phe,19-Gly-containing steroidal compound, we describe the detailed 2D NMR spectral analysis. Despite the large size and the conformational flexibility of the amino acid units in this molecule, conformational analysis by NOESY connectivities showed the existence of mainly one conformation (∼95%) in CDCl3 solution with approximately parallel orientation of the phenylalanine and glycine moieties.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Tetrahedron
T1  - Steroid template associated peptides: design, synthesis and 2D NMR characterization of a novel protected 18-Phe,19-Gly-containing steroidal compound
VL  - 63
IS  - 40
SP  - 9960
EP  - 9969
DO  - 10.1016/j.tet.2007.07.056
ER  - 

@article{
author = "Bjelaković, Mira and Krstić, Natalija and Juranić, Nenad and Dabović, Milan and Gojković, S.V. and Kessler, M. and Kalvoda, J. and Pavlović, Vladimir D.",
year = "2007",
abstract = "We report herein the synthesis of a novel modified steroid with two rigidly positioned amino acids in C- and N-protected forms (Gly-OtBu and N-Fmoc-l-Phe) at the angular positions (C-18 methylamino group and C-19 carboxylic function) of the steroid nucleus via amide bonds, starting from 18-cyanopregnenolone acetate over 10 steps. In an attempt to gain more insight into the structural and conformational features of this novel 18-Phe,19-Gly-containing steroidal compound, we describe the detailed 2D NMR spectral analysis. Despite the large size and the conformational flexibility of the amino acid units in this molecule, conformational analysis by NOESY connectivities showed the existence of mainly one conformation (∼95%) in CDCl3 solution with approximately parallel orientation of the phenylalanine and glycine moieties.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Tetrahedron",
title = "Steroid template associated peptides: design, synthesis and 2D NMR characterization of a novel protected 18-Phe,19-Gly-containing steroidal compound",
volume = "63",
number = "40",
pages = "9960-9969",
doi = "10.1016/j.tet.2007.07.056"
}

Bjelaković, M., Krstić, N., Juranić, N., Dabović, M., Gojković, S.V., Kessler, M., Kalvoda, J.,& Pavlović, V. D.. (2007). Steroid template associated peptides: design, synthesis and 2D NMR characterization of a novel protected 18-Phe,19-Gly-containing steroidal compound. in Tetrahedron
Oxford : Pergamon-Elsevier Science Ltd., 63(40), 9960-9969.
https://doi.org/10.1016/j.tet.2007.07.056

Bjelaković M, Krstić N, Juranić N, Dabović M, Gojković S, Kessler M, Kalvoda J, Pavlović VD. Steroid template associated peptides: design, synthesis and 2D NMR characterization of a novel protected 18-Phe,19-Gly-containing steroidal compound. in Tetrahedron. 2007;63(40):9960-9969.
doi:10.1016/j.tet.2007.07.056 .

Bjelaković, Mira, Krstić, Natalija, Juranić, Nenad, Dabović, Milan, Gojković, S.V., Kessler, M., Kalvoda, J., Pavlović, Vladimir D., "Steroid template associated peptides: design, synthesis and 2D NMR characterization of a novel protected 18-Phe,19-Gly-containing steroidal compound" in Tetrahedron, 63, no. 40 (2007):9960-9969,
https://doi.org/10.1016/j.tet.2007.07.056 . .

TY  - JOUR
AU  - Bjelaković, Mira
AU  - Krstić, Natalija
AU  - Tinant, Bernard
AU  - Kalvoda, Jaroslav
AU  - Csanadi, Janos
AU  - Pavlović, Vladimir D.
PY  - 2005
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4186
AB  - The conformations of (Z)‐ and (E)‐5‐oxo‐B‐nor‐5,10‐secocholest‐1(10)‐en‐3β‐yl acetates (2 and 3, resp.) were examined by a combination of X‐ray crystallographic analysis and NMR spectroscopy, with emphasis on the geometry of the cyclononenone moiety. The 1H‐ and 13C‐NMR spectra showed that the unsaturated nine‐membered ring of (E)‐isomer 3 in C6D6 and (D6)acetone solution exists in a sole conformation of type B1, which is similar to its solid‐state conformation. The (Z)‐isomer 2 in C6D6, CDCl3, and (D6)acetone solution, however, exists in two conformational forms of different families, with different orientation of the carbonyl group, the predominant form (85%) corresponding to the conformation of type A1 and the minor (15%) to the conformation A2 present also in the crystalline state. In this solid‐state conformations of the nine‐membered ring of both compounds, the 19‐Me and 5‐oxo groups are ‘β’‐oriented. The NMR analysis suggests that the nine‐membered ring of 4 has a conformation of type C1 in CDCl3 solution.
PB  - Wiley
T2  - Helvetica Chimica Acta
T1  - Conformations of the Nine-Membered Ring in the B-Nor-5,10-secosteroids. X-Ray and NMR Analysis
VL  - 88
IS  - 10
SP  - 2812
EP  - 2821
DO  - 10.1002/hlca.200590221
ER  - 

@article{
author = "Bjelaković, Mira and Krstić, Natalija and Tinant, Bernard and Kalvoda, Jaroslav and Csanadi, Janos and Pavlović, Vladimir D.",
year = "2005",
abstract = "The conformations of (Z)‐ and (E)‐5‐oxo‐B‐nor‐5,10‐secocholest‐1(10)‐en‐3β‐yl acetates (2 and 3, resp.) were examined by a combination of X‐ray crystallographic analysis and NMR spectroscopy, with emphasis on the geometry of the cyclononenone moiety. The 1H‐ and 13C‐NMR spectra showed that the unsaturated nine‐membered ring of (E)‐isomer 3 in C6D6 and (D6)acetone solution exists in a sole conformation of type B1, which is similar to its solid‐state conformation. The (Z)‐isomer 2 in C6D6, CDCl3, and (D6)acetone solution, however, exists in two conformational forms of different families, with different orientation of the carbonyl group, the predominant form (85%) corresponding to the conformation of type A1 and the minor (15%) to the conformation A2 present also in the crystalline state. In this solid‐state conformations of the nine‐membered ring of both compounds, the 19‐Me and 5‐oxo groups are ‘β’‐oriented. The NMR analysis suggests that the nine‐membered ring of 4 has a conformation of type C1 in CDCl3 solution.",
publisher = "Wiley",
journal = "Helvetica Chimica Acta",
title = "Conformations of the Nine-Membered Ring in the B-Nor-5,10-secosteroids. X-Ray and NMR Analysis",
volume = "88",
number = "10",
pages = "2812-2821",
doi = "10.1002/hlca.200590221"
}

Bjelaković, M., Krstić, N., Tinant, B., Kalvoda, J., Csanadi, J.,& Pavlović, Vladimir D.. (2005). Conformations of the Nine-Membered Ring in the B-Nor-5,10-secosteroids. X-Ray and NMR Analysis. in Helvetica Chimica Acta
Wiley., 88(10), 2812-2821.
https://doi.org/10.1002/hlca.200590221

Bjelaković M, Krstić N, Tinant B, Kalvoda J, Csanadi J, Pavlović V. Conformations of the Nine-Membered Ring in the B-Nor-5,10-secosteroids. X-Ray and NMR Analysis. in Helvetica Chimica Acta. 2005;88(10):2812-2821.
doi:10.1002/hlca.200590221 .

Bjelaković, Mira, Krstić, Natalija, Tinant, Bernard, Kalvoda, Jaroslav, Csanadi, Janos, Pavlović, Vladimir D., "Conformations of the Nine-Membered Ring in the B-Nor-5,10-secosteroids. X-Ray and NMR Analysis" in Helvetica Chimica Acta, 88, no. 10 (2005):2812-2821,
https://doi.org/10.1002/hlca.200590221 . .

TY  - JOUR
AU  - Pavlović, Vladimir D.
AU  - Dabović, Milan
AU  - Martinović, Saša B.
AU  - Lorenc, Ljubinka
AU  - Kalvoda, J
PY  - 2004
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2705
AB  - In the present paper, the preparation of 3β-hydroxy-17β-dimethyl- tert-butylsilyloxy-5-azaandrostane (15) in fourteen steps is described. B-nor-17-oxoandrost-5-en-3β-yl acetate (1) 1,2 was used as the starting material, which was transformed to the key intermediate of the synthesis, B-nor-17β-dimethyl-tert-butylsilyloxyandrost-4-en-3β-yl acetate (7).
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Synthesis of 5-azaandrostane-3β,17β-diol protected at the 17β-hydroxyl group
VL  - 69
IS  - 11
SP  - 861
EP  - 869
DO  - 10.2298/JSC0411861P
ER  - 

@article{
author = "Pavlović, Vladimir D. and Dabović, Milan and Martinović, Saša B. and Lorenc, Ljubinka and Kalvoda, J",
year = "2004",
abstract = "In the present paper, the preparation of 3β-hydroxy-17β-dimethyl- tert-butylsilyloxy-5-azaandrostane (15) in fourteen steps is described. B-nor-17-oxoandrost-5-en-3β-yl acetate (1) 1,2 was used as the starting material, which was transformed to the key intermediate of the synthesis, B-nor-17β-dimethyl-tert-butylsilyloxyandrost-4-en-3β-yl acetate (7).",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis of 5-azaandrostane-3β,17β-diol protected at the 17β-hydroxyl group",
volume = "69",
number = "11",
pages = "861-869",
doi = "10.2298/JSC0411861P"
}

Pavlović, V. D., Dabović, M., Martinović, S. B., Lorenc, L.,& Kalvoda, J.. (2004). Synthesis of 5-azaandrostane-3β,17β-diol protected at the 17β-hydroxyl group. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 69(11), 861-869.
https://doi.org/10.2298/JSC0411861P

Pavlović VD, Dabović M, Martinović SB, Lorenc L, Kalvoda J. Synthesis of 5-azaandrostane-3β,17β-diol protected at the 17β-hydroxyl group. in Journal of the Serbian Chemical Society. 2004;69(11):861-869.
doi:10.2298/JSC0411861P .

Pavlović, Vladimir D., Dabović, Milan, Martinović, Saša B., Lorenc, Ljubinka, Kalvoda, J, "Synthesis of 5-azaandrostane-3β,17β-diol protected at the 17β-hydroxyl group" in Journal of the Serbian Chemical Society, 69, no. 11 (2004):861-869,
https://doi.org/10.2298/JSC0411861P . .

TY  - JOUR
AU  - Krstić, Natalija
AU  - Bjelaković, Mira
AU  - Dabović, Milan
AU  - Lorenc, Ljubinka
AU  - Pavlović, Vladimir D.
PY  - 2004
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/148
AB  - Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime (4) (prepared in 4 steps starting from cholest-5-en-3β-ol ο1)) with thionyl chloride in dioxane solution afforded an enamide-type lactam, i.e. 7-aza-B-homocholest-4-en-6-one (6) as a single product. Photoreaction of the same compound in methanol or benzene-acetic acid solution gave a mixture of products, with the formation of the parent ketone 3 and the occurrence of Z/E isomerization, while the lactam 6 was obtained only when the reaction was performed in methanol and then in very low yield (7%).
AB  - Bekmanovo premeštanje (Z)-holest-4-en-6-on oksima (4) (koji je dobijen u 4 faze, polazeći od holest-5-en-3 β-ola (1)) sa tionil-hloridom u dioksanskom rastvoru, kao jedini proizvod daje laktam enamidnog tipa, tj. 7-aza-B-homoholest-4-en-6-on (6). Fotoreakcijom istog jedinjenja u metanolu ili u rastvoru benzen-sirćetna kiselina, nastaje smesa proizvoda koju čine polazni keton 3 i proizvodi Z/E izomerizacije, dok je laktam 6 dobiven u vrlo niskom prinosu (7%) samo u metanolnom rastvoru.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime
T1  - Fotohemijsko i Bekmanovo premeštanje(z)-holest-4-en-6-on oksima
VL  - 69
IS  - 6
SP  - 413
EP  - 420
DO  - 10.2298/JSC0406413K
ER  - 

@article{
author = "Krstić, Natalija and Bjelaković, Mira and Dabović, Milan and Lorenc, Ljubinka and Pavlović, Vladimir D.",
year = "2004",
abstract = "Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime (4) (prepared in 4 steps starting from cholest-5-en-3β-ol ο1)) with thionyl chloride in dioxane solution afforded an enamide-type lactam, i.e. 7-aza-B-homocholest-4-en-6-one (6) as a single product. Photoreaction of the same compound in methanol or benzene-acetic acid solution gave a mixture of products, with the formation of the parent ketone 3 and the occurrence of Z/E isomerization, while the lactam 6 was obtained only when the reaction was performed in methanol and then in very low yield (7%)., Bekmanovo premeštanje (Z)-holest-4-en-6-on oksima (4) (koji je dobijen u 4 faze, polazeći od holest-5-en-3 β-ola (1)) sa tionil-hloridom u dioksanskom rastvoru, kao jedini proizvod daje laktam enamidnog tipa, tj. 7-aza-B-homoholest-4-en-6-on (6). Fotoreakcijom istog jedinjenja u metanolu ili u rastvoru benzen-sirćetna kiselina, nastaje smesa proizvoda koju čine polazni keton 3 i proizvodi Z/E izomerizacije, dok je laktam 6 dobiven u vrlo niskom prinosu (7%) samo u metanolnom rastvoru.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime, Fotohemijsko i Bekmanovo premeštanje(z)-holest-4-en-6-on oksima",
volume = "69",
number = "6",
pages = "413-420",
doi = "10.2298/JSC0406413K"
}

Krstić, N., Bjelaković, M., Dabović, M., Lorenc, L.,& Pavlović, V. D.. (2004). Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 69(6), 413-420.
https://doi.org/10.2298/JSC0406413K

Krstić N, Bjelaković M, Dabović M, Lorenc L, Pavlović VD. Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime. in Journal of the Serbian Chemical Society. 2004;69(6):413-420.
doi:10.2298/JSC0406413K .

Krstić, Natalija, Bjelaković, Mira, Dabović, Milan, Lorenc, Ljubinka, Pavlović, Vladimir D., "Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime" in Journal of the Serbian Chemical Society, 69, no. 6 (2004):413-420,
https://doi.org/10.2298/JSC0406413K . .

TY  - JOUR
AU  - Bjelaković, Mira
AU  - Lorenc, Ljubinka
AU  - Pavlović, Vladimir D.
AU  - Tinant, Bernard
AU  - Declercq, Jean-Paul
AU  - Kalvoda, Jaroslav
PY  - 2003
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4187
AB  - Oxidations of 5α‐hydroxy‐B‐norcholestan‐3β‐yl acetate (8) with Pb(OAc)4 under thermal or photolytic conditions or in the presence of iodine afforded only complex mixtures of compounds. However, the HgO/I2 version of the hypoiodite reaction gave as the primary products the stereoisomeric (Z)‐ and (E)‐1(10)‐unsaturated 5,10‐seco B‐nor‐derivatives 10 and 11, and the stereoisomeric (5R,10R)‐ and (5S,10S)‐acetals 14 and 15 (Scheme 4). Further reaction of these compounds under conditions of their formation afforded, in addition, the A‐nor 1,5‐cyclization products 13 and 16 (from 10) and 12 (from 11) (see also Scheme 6) and the 6‐iodo‐5,6‐secolactones 17 and 19 (from 14 and 15, resp.) and 4‐iodo‐4,5‐secolactone 18 (from 15) (see also Scheme 7). Oxidations of 5β‐hydroxy‐B‐norcholestan‐3β‐yl acetate (9) with both hypoiodite‐forming reagents (Pb(OAc)4/I2 and HgO/I2) proceeded similarly to the HgO/I2 reaction of the corresponding 5α‐hydroxy analogue 8. Photolytic Pb(OAc)4 oxidation of 9 afforded, in addition to the (Z)‐ and (E)‐5,10‐seco 1(10)‐unsaturated ketones 10 and 11, their isomeric 5,10‐seco 10(19)‐unsaturated ketone 22, the acetal 5‐acetate 21, and 5β,19‐epoxy derivative 23 (Scheme 9). Exceptionally, in the thermal Pb(OAc)4 oxidation of 9, the 5,10‐seco ketones 10, 11, and 22 were not formed, the only reaction being the stereoselective formation of the 5,10‐ethers with the β‐oriented epoxy bridge, i.e. the (10R)‐enol ether 20 and (5S,10R)‐acetal 5‐acetate 21 (Scheme 8). Possible mechanistic interpretations of the above transformations are discussed.
PB  - Wiley
T2  - Helvetica Chimica Acta
T1  - Oxidative Fragmentations of the 5-alpha and 5-beta-Hydroxy-B-norcholestan-3-beta-yl Acetates
VL  - 86
IS  - 6
SP  - 2121
EP  - 2135
DO  - 10.1002/hlca.200390169
ER  - 

@article{
author = "Bjelaković, Mira and Lorenc, Ljubinka and Pavlović, Vladimir D. and Tinant, Bernard and Declercq, Jean-Paul and Kalvoda, Jaroslav",
year = "2003",
abstract = "Oxidations of 5α‐hydroxy‐B‐norcholestan‐3β‐yl acetate (8) with Pb(OAc)4 under thermal or photolytic conditions or in the presence of iodine afforded only complex mixtures of compounds. However, the HgO/I2 version of the hypoiodite reaction gave as the primary products the stereoisomeric (Z)‐ and (E)‐1(10)‐unsaturated 5,10‐seco B‐nor‐derivatives 10 and 11, and the stereoisomeric (5R,10R)‐ and (5S,10S)‐acetals 14 and 15 (Scheme 4). Further reaction of these compounds under conditions of their formation afforded, in addition, the A‐nor 1,5‐cyclization products 13 and 16 (from 10) and 12 (from 11) (see also Scheme 6) and the 6‐iodo‐5,6‐secolactones 17 and 19 (from 14 and 15, resp.) and 4‐iodo‐4,5‐secolactone 18 (from 15) (see also Scheme 7). Oxidations of 5β‐hydroxy‐B‐norcholestan‐3β‐yl acetate (9) with both hypoiodite‐forming reagents (Pb(OAc)4/I2 and HgO/I2) proceeded similarly to the HgO/I2 reaction of the corresponding 5α‐hydroxy analogue 8. Photolytic Pb(OAc)4 oxidation of 9 afforded, in addition to the (Z)‐ and (E)‐5,10‐seco 1(10)‐unsaturated ketones 10 and 11, their isomeric 5,10‐seco 10(19)‐unsaturated ketone 22, the acetal 5‐acetate 21, and 5β,19‐epoxy derivative 23 (Scheme 9). Exceptionally, in the thermal Pb(OAc)4 oxidation of 9, the 5,10‐seco ketones 10, 11, and 22 were not formed, the only reaction being the stereoselective formation of the 5,10‐ethers with the β‐oriented epoxy bridge, i.e. the (10R)‐enol ether 20 and (5S,10R)‐acetal 5‐acetate 21 (Scheme 8). Possible mechanistic interpretations of the above transformations are discussed.",
publisher = "Wiley",
journal = "Helvetica Chimica Acta",
title = "Oxidative Fragmentations of the 5-alpha and 5-beta-Hydroxy-B-norcholestan-3-beta-yl Acetates",
volume = "86",
number = "6",
pages = "2121-2135",
doi = "10.1002/hlca.200390169"
}

Bjelaković, M., Lorenc, L., Pavlović, Vladimir D., Tinant, B., Declercq, J.,& Kalvoda, J.. (2003). Oxidative Fragmentations of the 5-alpha and 5-beta-Hydroxy-B-norcholestan-3-beta-yl Acetates. in Helvetica Chimica Acta
Wiley., 86(6), 2121-2135.
https://doi.org/10.1002/hlca.200390169

Bjelaković M, Lorenc L, Pavlović V, Tinant B, Declercq J, Kalvoda J. Oxidative Fragmentations of the 5-alpha and 5-beta-Hydroxy-B-norcholestan-3-beta-yl Acetates. in Helvetica Chimica Acta. 2003;86(6):2121-2135.
doi:10.1002/hlca.200390169 .

Bjelaković, Mira, Lorenc, Ljubinka, Pavlović, Vladimir D., Tinant, Bernard, Declercq, Jean-Paul, Kalvoda, Jaroslav, "Oxidative Fragmentations of the 5-alpha and 5-beta-Hydroxy-B-norcholestan-3-beta-yl Acetates" in Helvetica Chimica Acta, 86, no. 6 (2003):2121-2135,
https://doi.org/10.1002/hlca.200390169 . .

TY  - JOUR
AU  - Krstić, Natalija
AU  - Bjelaković, Mira
AU  - Lorenc, Ljubinka
AU  - Pavlović, Vladimir D.
PY  - 2003
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/109
AB  - 5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate (11) was prepared in 5 steps starting from (E)-3β-acetoxy-5,10-seco-1(10)-cholesten-5-one (6). Treatment of the 1-oxo-5-hydroxy derivative 11 with lead tetraacetate (LTA) (under thermal or hypoiodite conditions) or with mercuric oxide/iodine (HgO/I2) reagent resulted in the oxidative β-fragmentation of the C(5)–C(10) bond affording 1,5-dioxo-5,10-secocholest-10(19)-en-3β-yl acetate (12), in different yields, depending on the reagent. Also the stereochemistry of the 1β,6β-cyclization product 13, formed by transannular cyclization of the 1,5-diketone 12 on silica gel, is discussed in this work.
AB  - Sintetizovan je 5-hidroksi-1-okso-5α-holestan-3β-il-acetata (11) u 5 faza polazeći od (E)- 3β-acetoksi-5,10-seko-1(10)-holesten-5-ona (6). Dejstvom olovo-tetraacetata (LTA) (pod termičkim ili hipojoditnim uslovima), ili merkuri-oksid/jodnog reagensa (HgO/I2) na 1-okso-5-hidroksi derivat 11, vrši se oksidativna β-fragmentacija njegove C(5)–C(10) veze, pri čemu se dobija 1,5-diokso-5,10-sekoholest-10(19)-en-3β-il-acetat (12), u različitim prinosima u zavisnosti od upotrebljenog reagensa. Takođe, diskutovana je stereohemija 1β,6β-ciklizacionog proizvoda 13, nastalog intramolekulskom ciklizacijom 1,5-diokso-5,10-seko jedinjenja 12 na silika gelu.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Oxidative fragmentation of 5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate
T1  - Oksidativne fragmentacije 5-hidroksi-1-okso-5α-holestan-3β-il-acetata
VL  - 68
IS  - 11
SP  - 785
EP  - 794
DO  - 10.2298/JSC0311785K
ER  - 

@article{
author = "Krstić, Natalija and Bjelaković, Mira and Lorenc, Ljubinka and Pavlović, Vladimir D.",
year = "2003",
abstract = "5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate (11) was prepared in 5 steps starting from (E)-3β-acetoxy-5,10-seco-1(10)-cholesten-5-one (6). Treatment of the 1-oxo-5-hydroxy derivative 11 with lead tetraacetate (LTA) (under thermal or hypoiodite conditions) or with mercuric oxide/iodine (HgO/I2) reagent resulted in the oxidative β-fragmentation of the C(5)–C(10) bond affording 1,5-dioxo-5,10-secocholest-10(19)-en-3β-yl acetate (12), in different yields, depending on the reagent. Also the stereochemistry of the 1β,6β-cyclization product 13, formed by transannular cyclization of the 1,5-diketone 12 on silica gel, is discussed in this work., Sintetizovan je 5-hidroksi-1-okso-5α-holestan-3β-il-acetata (11) u 5 faza polazeći od (E)- 3β-acetoksi-5,10-seko-1(10)-holesten-5-ona (6). Dejstvom olovo-tetraacetata (LTA) (pod termičkim ili hipojoditnim uslovima), ili merkuri-oksid/jodnog reagensa (HgO/I2) na 1-okso-5-hidroksi derivat 11, vrši se oksidativna β-fragmentacija njegove C(5)–C(10) veze, pri čemu se dobija 1,5-diokso-5,10-sekoholest-10(19)-en-3β-il-acetat (12), u različitim prinosima u zavisnosti od upotrebljenog reagensa. Takođe, diskutovana je stereohemija 1β,6β-ciklizacionog proizvoda 13, nastalog intramolekulskom ciklizacijom 1,5-diokso-5,10-seko jedinjenja 12 na silika gelu.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Oxidative fragmentation of 5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate, Oksidativne fragmentacije 5-hidroksi-1-okso-5α-holestan-3β-il-acetata",
volume = "68",
number = "11",
pages = "785-794",
doi = "10.2298/JSC0311785K"
}

Krstić, N., Bjelaković, M., Lorenc, L.,& Pavlović, V. D.. (2003). Oxidative fragmentation of 5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 68(11), 785-794.
https://doi.org/10.2298/JSC0311785K

Krstić N, Bjelaković M, Lorenc L, Pavlović VD. Oxidative fragmentation of 5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate. in Journal of the Serbian Chemical Society. 2003;68(11):785-794.
doi:10.2298/JSC0311785K .

Krstić, Natalija, Bjelaković, Mira, Lorenc, Ljubinka, Pavlović, Vladimir D., "Oxidative fragmentation of 5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate" in Journal of the Serbian Chemical Society, 68, no. 11 (2003):785-794,
https://doi.org/10.2298/JSC0311785K . .

TY  - JOUR
AU  - Bjelaković, Mira
AU  - Pavlović, Vladimir D.
AU  - Dabović, Milan
AU  - Lorenc, Ljubinka
PY  - 2003
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/115
AB  - The acid-catalyzed reaction of (Z)- and (E)-B-nor-5,10-seco-ketones 2 and 3 resulted in an intramolecular cyclization to give the 5-hydroxy-A-nor-1β,5β-10(19)-methylidene derivative 8, the 5β-hydroxy-A-nor-1(10)-unsaturated compound 9 and the 5β,10β-dihydroxy A-nor-product 10, from the (Z)-isomer and the 5-hydroxy-A-nor-1β,5β-10(19)-methylidene product 11, from the (E)-isomer. Upon UV-irradiation, the (Z)- and (E)-seco-ketones 2 and 3 underwent a reversible (Z)/(E) and (E)/(Z)-isomerization and in addition to a transannular photocyclization to afford the 10(19)-methylidene derivatives 8 and 11, respectively, while photolysis of the 10(19)-methylidene-B-nor-5,10-seco-ketone 4 gave the oxetane derivative 12.
AB  - Kiselo-katalizovana reakcija (Z)- i (E)-B-nor-5,10-seko-ketona 2 i 3 rezultuje u intramolekulskoj ciklizaciji dajući 5-hidroksi-A-nor-1β,5β-10(19)-metilidenski derivat 8, 5β-hidroksi A-nor-1(10)-nezasićeno jedinjenje 9 i 5β,10β-dihidroksi-A-nor-proizvod 10, iz Z-izomera, i 5-hidroksi-A-nor-1β,5β-10(19)-metilidenski proizvod 11, iz E-izomera. (Z)- i (E)-Seko- ketoni 2 i 3 UV-ozračivanjem podležu reverzibilnoj (Z)/(E) odnosno (E)/(Z) izomerizaciji, kao i transanularnoj fotociklizaciji dajući 10(19)-metilidenske derivate 8 odnosno 11, dok se fotolizom 10(19)-metilidenskog-5,10-seko-ketona 4 gradi oksetanski derivat 12.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Acid-catalyzed and photolytic reactivity of some unsaturated B-nor-5, 10-secosteroidal ketones
T1  - Kiselo-katalizovana i fotolitička reaktivnost nekih nezasićenih B-nor-5,10-sekosteroidnih ketona
VL  - 68
IS  - 4-5
SP  - 303
EP  - 312
DO  - 10.2298/JSC0305303B
ER  - 

@article{
author = "Bjelaković, Mira and Pavlović, Vladimir D. and Dabović, Milan and Lorenc, Ljubinka",
year = "2003",
abstract = "The acid-catalyzed reaction of (Z)- and (E)-B-nor-5,10-seco-ketones 2 and 3 resulted in an intramolecular cyclization to give the 5-hydroxy-A-nor-1β,5β-10(19)-methylidene derivative 8, the 5β-hydroxy-A-nor-1(10)-unsaturated compound 9 and the 5β,10β-dihydroxy A-nor-product 10, from the (Z)-isomer and the 5-hydroxy-A-nor-1β,5β-10(19)-methylidene product 11, from the (E)-isomer. Upon UV-irradiation, the (Z)- and (E)-seco-ketones 2 and 3 underwent a reversible (Z)/(E) and (E)/(Z)-isomerization and in addition to a transannular photocyclization to afford the 10(19)-methylidene derivatives 8 and 11, respectively, while photolysis of the 10(19)-methylidene-B-nor-5,10-seco-ketone 4 gave the oxetane derivative 12., Kiselo-katalizovana reakcija (Z)- i (E)-B-nor-5,10-seko-ketona 2 i 3 rezultuje u intramolekulskoj ciklizaciji dajući 5-hidroksi-A-nor-1β,5β-10(19)-metilidenski derivat 8, 5β-hidroksi A-nor-1(10)-nezasićeno jedinjenje 9 i 5β,10β-dihidroksi-A-nor-proizvod 10, iz Z-izomera, i 5-hidroksi-A-nor-1β,5β-10(19)-metilidenski proizvod 11, iz E-izomera. (Z)- i (E)-Seko- ketoni 2 i 3 UV-ozračivanjem podležu reverzibilnoj (Z)/(E) odnosno (E)/(Z) izomerizaciji, kao i transanularnoj fotociklizaciji dajući 10(19)-metilidenske derivate 8 odnosno 11, dok se fotolizom 10(19)-metilidenskog-5,10-seko-ketona 4 gradi oksetanski derivat 12.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Acid-catalyzed and photolytic reactivity of some unsaturated B-nor-5, 10-secosteroidal ketones, Kiselo-katalizovana i fotolitička reaktivnost nekih nezasićenih B-nor-5,10-sekosteroidnih ketona",
volume = "68",
number = "4-5",
pages = "303-312",
doi = "10.2298/JSC0305303B"
}

Bjelaković, M., Pavlović, V. D., Dabović, M.,& Lorenc, L.. (2003). Acid-catalyzed and photolytic reactivity of some unsaturated B-nor-5, 10-secosteroidal ketones. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 68(4-5), 303-312.
https://doi.org/10.2298/JSC0305303B

Bjelaković M, Pavlović VD, Dabović M, Lorenc L. Acid-catalyzed and photolytic reactivity of some unsaturated B-nor-5, 10-secosteroidal ketones. in Journal of the Serbian Chemical Society. 2003;68(4-5):303-312.
doi:10.2298/JSC0305303B .

Bjelaković, Mira, Pavlović, Vladimir D., Dabović, Milan, Lorenc, Ljubinka, "Acid-catalyzed and photolytic reactivity of some unsaturated B-nor-5, 10-secosteroidal ketones" in Journal of the Serbian Chemical Society, 68, no. 4-5 (2003):303-312,
https://doi.org/10.2298/JSC0305303B . .

TY  - JOUR
AU  - Bjelaković, Mira
AU  - Pavlović, Vladimir D.
AU  - Lorenc, Ljubinka
PY  - 2002
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/60
AB  - B-Norcholestane epoxide 2 is reduced with lithium aluminium hydride to give either the 3β,6α-diol 3 or the corresponding 3β,5α-diol 4, depending on the quality of the reducing reagent employed. Aplausible mechanistic explanation of the obtained results is suggested.
AB  - Redukcijom B-norholestan-epoksida 2 pomoću litijum-aluminijum-hidrida dobijeni su odgovarajući 3β,6α-diol 3 ili 3β,5α-diol 4, u zavisnosti od kvaliteta upotrebljenog redukcionog reagensa. Predloženo je verovatno mehanističko tumačenje dobijenih rezultata.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Hydride reduction of B-norcholestane 5α,6α-epoxide
T1  - Hidridna redukcija B-norholestan 5α,6α-epoksida
VL  - 67
IS  - 2
SP  - 69
EP  - 75
DO  - 10.2298/JSC0202069B
ER  - 

@article{
author = "Bjelaković, Mira and Pavlović, Vladimir D. and Lorenc, Ljubinka",
year = "2002",
abstract = "B-Norcholestane epoxide 2 is reduced with lithium aluminium hydride to give either the 3β,6α-diol 3 or the corresponding 3β,5α-diol 4, depending on the quality of the reducing reagent employed. Aplausible mechanistic explanation of the obtained results is suggested., Redukcijom B-norholestan-epoksida 2 pomoću litijum-aluminijum-hidrida dobijeni su odgovarajući 3β,6α-diol 3 ili 3β,5α-diol 4, u zavisnosti od kvaliteta upotrebljenog redukcionog reagensa. Predloženo je verovatno mehanističko tumačenje dobijenih rezultata.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Hydride reduction of B-norcholestane 5α,6α-epoxide, Hidridna redukcija B-norholestan 5α,6α-epoksida",
volume = "67",
number = "2",
pages = "69-75",
doi = "10.2298/JSC0202069B"
}

Bjelaković, M., Pavlović, V. D.,& Lorenc, L.. (2002). Hydride reduction of B-norcholestane 5α,6α-epoxide. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 67(2), 69-75.
https://doi.org/10.2298/JSC0202069B

Bjelaković M, Pavlović VD, Lorenc L. Hydride reduction of B-norcholestane 5α,6α-epoxide. in Journal of the Serbian Chemical Society. 2002;67(2):69-75.
doi:10.2298/JSC0202069B .

Bjelaković, Mira, Pavlović, Vladimir D., Lorenc, Ljubinka, "Hydride reduction of B-norcholestane 5α,6α-epoxide" in Journal of the Serbian Chemical Society, 67, no. 2 (2002):69-75,
https://doi.org/10.2298/JSC0202069B . .

TY  - JOUR
AU  - Bjelaković, Mira
AU  - Pavlović, Vladimir D.
AU  - Lorenc, Ljubinka
AU  - Tinant, Bernard
AU  - Declercq, Jean-Paul
PY  - 2000
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/16
AB  - The crystal structure of 14-oxo-13,14-seco-5α-cholest-13(18)-en-3β-yl acetate (2), obtained (in addition to the (E)-Δ12-isomer 3) by oxidative fragmentation of the C(13)-C(14) bond of 14α-hydroxy-5α-cholestan-3β-yl acetate (1), was determined by X-ray analysis. In addition, the configurations of the acetoxy derivatives 4-6, formed by the thermal lead tetraacetate oxidation of 1, were deduced from the relevant 1H-NMR parameters.
AB  - Kristalna struktura 14-okso-13,14-seko-5α-holest-13(18)-en-3β-il-acetata (2). koji se dobiva (pored (E)-Δ12-izomera 3) oksidativnom fragmentacijom C(13)-C(14) veze 14α-hidroksi-5α-holestan-3β-il-acetata (1) određena je analizom X-zraka. Pored toga, konfiguracije njegovih acetoksi derivata 4-6, koji se grade pri termičkoj olovo-tetraacetatnoj oksidaciji, izvedene su na osnovu odgovarajućih 1H-NMR parametara.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - The crystal structure of 14-oxo-13,14-seco-5α-cholest-13(18)-en-3β-yl acetate and the assignment of the configuration of its acetoxy derivatives
T1  - Kristalna struktura 14-okso-13,14-seko-5α-holest-13(18)-en-3β-il-acetata i određivanje konfiguracije njegovih acetoksi derivata
VL  - 65
IS  - 8
SP  - 541
EP  - 547
UR  - https://hdl.handle.net/21.15107/rcub_cer_16
ER  - 

@article{
author = "Bjelaković, Mira and Pavlović, Vladimir D. and Lorenc, Ljubinka and Tinant, Bernard and Declercq, Jean-Paul",
year = "2000",
abstract = "The crystal structure of 14-oxo-13,14-seco-5α-cholest-13(18)-en-3β-yl acetate (2), obtained (in addition to the (E)-Δ12-isomer 3) by oxidative fragmentation of the C(13)-C(14) bond of 14α-hydroxy-5α-cholestan-3β-yl acetate (1), was determined by X-ray analysis. In addition, the configurations of the acetoxy derivatives 4-6, formed by the thermal lead tetraacetate oxidation of 1, were deduced from the relevant 1H-NMR parameters., Kristalna struktura 14-okso-13,14-seko-5α-holest-13(18)-en-3β-il-acetata (2). koji se dobiva (pored (E)-Δ12-izomera 3) oksidativnom fragmentacijom C(13)-C(14) veze 14α-hidroksi-5α-holestan-3β-il-acetata (1) određena je analizom X-zraka. Pored toga, konfiguracije njegovih acetoksi derivata 4-6, koji se grade pri termičkoj olovo-tetraacetatnoj oksidaciji, izvedene su na osnovu odgovarajućih 1H-NMR parametara.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "The crystal structure of 14-oxo-13,14-seco-5α-cholest-13(18)-en-3β-yl acetate and the assignment of the configuration of its acetoxy derivatives, Kristalna struktura 14-okso-13,14-seko-5α-holest-13(18)-en-3β-il-acetata i određivanje konfiguracije njegovih acetoksi derivata",
volume = "65",
number = "8",
pages = "541-547",
url = "https://hdl.handle.net/21.15107/rcub_cer_16"
}

Bjelaković, M., Pavlović, V. D., Lorenc, L., Tinant, B.,& Declercq, J.. (2000). The crystal structure of 14-oxo-13,14-seco-5α-cholest-13(18)-en-3β-yl acetate and the assignment of the configuration of its acetoxy derivatives. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 65(8), 541-547.
https://hdl.handle.net/21.15107/rcub_cer_16

Bjelaković M, Pavlović VD, Lorenc L, Tinant B, Declercq J. The crystal structure of 14-oxo-13,14-seco-5α-cholest-13(18)-en-3β-yl acetate and the assignment of the configuration of its acetoxy derivatives. in Journal of the Serbian Chemical Society. 2000;65(8):541-547.
https://hdl.handle.net/21.15107/rcub_cer_16 .

Bjelaković, Mira, Pavlović, Vladimir D., Lorenc, Ljubinka, Tinant, Bernard, Declercq, Jean-Paul, "The crystal structure of 14-oxo-13,14-seco-5α-cholest-13(18)-en-3β-yl acetate and the assignment of the configuration of its acetoxy derivatives" in Journal of the Serbian Chemical Society, 65, no. 8 (2000):541-547,
https://hdl.handle.net/21.15107/rcub_cer_16 .