TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Jevtić, Sanja
AU  - Jeremić, Sanja
AU  - Đokić, Lidija
AU  - Đonlagić, Jasna
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5392
AB  - The present study reports the potential application of star-shaped poly(ε-caprolactones) with different number of arms as new drug delivery matrix. Linear and star-shaped PCL ibuprofen loaded microspheres were prepared using oil-in-water (o/w) solvent evaporation technique and characterized with FTIR, DSC, XRD and SEM analysis. High yield, encapsulation efficiency and drug loadings were obtained for all microspheres. FTIR analysis revealed the existence of interactions between polymer matrix and drug, while the DSC analysis suggested that drug was encapsulated in an amorphous form. SEM analysis confirmed that regular, spherical in shape star-shaped microspheres, with diameter between 80 and 90 μm, were obtained, while quite larger microspheres, 110 μm, were prepared from linear PCL. The advantage of using star-shaped PCL microspheres instead of linear PCL was seen from drug release profiles which demonstrated higher amount of drug released from star-shaped polymer matrix as a consequence of their branched, flexible structure. Microspheres prepared from the polymers with the most branched structure showed the highest amount of the released drug after 24 h. Finally, cytotoxicity tests, performed using normal human fibroblasts (MRC5), indicated the absence of cytotoxicity at lower concentrations of microspheres proving the great potential of star-shaped PCL systems in comparison to linear ones.
AB  - У оквиру ове студије је приказана потенцијална примена разгранатих поли(ε-кап-
ролактона) са различитим бројем грана као новог полимерног матрикса за уношење
лекова у организам. Микросфере линеарног и разгранатих PCL са инкапсулираним ибу-
профеном су припремљене применом технике отпаравања лако испарљивог растварача
из емулзије “уље у води” (oil-in-water, o/w) и карактерисане помоћу FTIR, DSC, XRD и
SEM анализе. За све микросфере су добијени висок принос, висока ефикасност инкaпсу-
лације и висок садржај лека. FTIR анализом је потврђено постојање интеракција између
полимерног матрикса и лека, док је DSC анализа указала да је лек инкапсулиран у
аморфном облику. SEM анализа је потврдила да су добијене микросфере разгранатих
PCL правилног, сферичног облика, са пречником између 80 до 90 μm, док су знатно веће
микросфере, 110 μm, припремљене од линеарног PCL. Предност употребе микросфера
разгранатих PCL уместо линеарног PCL се види из профила отпуштања лека, који су
показали већу количину отпуштеног лека из микросфера разгранатог полимернe мат-
рице као последица њихове разгранате, флексибилне структуре. Микросфере припре-
мљене од полимера са најразгранитијом структуром су показале највећу количину
отпуштеног лека након 24 h. Тестови цитотоксичности, изведени коришћењем ћелија
нормалних, хуманих фибробласта (MRC5), показали су одсуство цитотоксичности при
нижим концентрацијама микросфера доказујући велики потенцијал разгранатих PCL
система у поређењу са линеарним.
PB  - Serbia : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Star-shaped poly(ε-caprolactones) with well-defined architecture as potential drug carriers
T1  - Разгранати поли (ε-капролактони) са добро одређеном архитектуром као потенцијални носачи лекова
VL  - 87
IS  - 9
SP  - 1075
EP  - 1090
DO  - 10.2298/JSC220202032P
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Jevtić, Sanja and Jeremić, Sanja and Đokić, Lidija and Đonlagić, Jasna",
year = "2022",
abstract = "The present study reports the potential application of star-shaped poly(ε-caprolactones) with different number of arms as new drug delivery matrix. Linear and star-shaped PCL ibuprofen loaded microspheres were prepared using oil-in-water (o/w) solvent evaporation technique and characterized with FTIR, DSC, XRD and SEM analysis. High yield, encapsulation efficiency and drug loadings were obtained for all microspheres. FTIR analysis revealed the existence of interactions between polymer matrix and drug, while the DSC analysis suggested that drug was encapsulated in an amorphous form. SEM analysis confirmed that regular, spherical in shape star-shaped microspheres, with diameter between 80 and 90 μm, were obtained, while quite larger microspheres, 110 μm, were prepared from linear PCL. The advantage of using star-shaped PCL microspheres instead of linear PCL was seen from drug release profiles which demonstrated higher amount of drug released from star-shaped polymer matrix as a consequence of their branched, flexible structure. Microspheres prepared from the polymers with the most branched structure showed the highest amount of the released drug after 24 h. Finally, cytotoxicity tests, performed using normal human fibroblasts (MRC5), indicated the absence of cytotoxicity at lower concentrations of microspheres proving the great potential of star-shaped PCL systems in comparison to linear ones., У оквиру ове студије је приказана потенцијална примена разгранатих поли(ε-кап-
ролактона) са различитим бројем грана као новог полимерног матрикса за уношење
лекова у организам. Микросфере линеарног и разгранатих PCL са инкапсулираним ибу-
профеном су припремљене применом технике отпаравања лако испарљивог растварача
из емулзије “уље у води” (oil-in-water, o/w) и карактерисане помоћу FTIR, DSC, XRD и
SEM анализе. За све микросфере су добијени висок принос, висока ефикасност инкaпсу-
лације и висок садржај лека. FTIR анализом је потврђено постојање интеракција између
полимерног матрикса и лека, док је DSC анализа указала да је лек инкапсулиран у
аморфном облику. SEM анализа је потврдила да су добијене микросфере разгранатих
PCL правилног, сферичног облика, са пречником између 80 до 90 μm, док су знатно веће
микросфере, 110 μm, припремљене од линеарног PCL. Предност употребе микросфера
разгранатих PCL уместо линеарног PCL се види из профила отпуштања лека, који су
показали већу количину отпуштеног лека из микросфера разгранатог полимернe мат-
рице као последица њихове разгранате, флексибилне структуре. Микросфере припре-
мљене од полимера са најразгранитијом структуром су показале највећу количину
отпуштеног лека након 24 h. Тестови цитотоксичности, изведени коришћењем ћелија
нормалних, хуманих фибробласта (MRC5), показали су одсуство цитотоксичности при
нижим концентрацијама микросфера доказујући велики потенцијал разгранатих PCL
система у поређењу са линеарним.",
publisher = "Serbia : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Star-shaped poly(ε-caprolactones) with well-defined architecture as potential drug carriers, Разгранати поли (ε-капролактони) са добро одређеном архитектуром као потенцијални носачи лекова",
volume = "87",
number = "9",
pages = "1075-1090",
doi = "10.2298/JSC220202032P"
}

Ponjavić, M., Nikolić, M. S., Jevtić, S., Jeremić, S., Đokić, L.,& Đonlagić, J.. (2022). Star-shaped poly(ε-caprolactones) with well-defined architecture as potential drug carriers. in Journal of the Serbian Chemical Society
Serbia : Serbian Chemical Society., 87(9), 1075-1090.
https://doi.org/10.2298/JSC220202032P

Ponjavić M, Nikolić MS, Jevtić S, Jeremić S, Đokić L, Đonlagić J. Star-shaped poly(ε-caprolactones) with well-defined architecture as potential drug carriers. in Journal of the Serbian Chemical Society. 2022;87(9):1075-1090.
doi:10.2298/JSC220202032P .

Ponjavić, Marijana, Nikolić, Marija S., Jevtić, Sanja, Jeremić, Sanja, Đokić, Lidija, Đonlagić, Jasna, "Star-shaped poly(ε-caprolactones) with well-defined architecture as potential drug carriers" in Journal of the Serbian Chemical Society, 87, no. 9 (2022):1075-1090,
https://doi.org/10.2298/JSC220202032P . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Stevanović, Sanja
AU  - Nikodinović-Runić, Jasmina
AU  - Jeremić, Sanja
AU  - Pavić, Aleksandar
AU  - Đongalić, Jasna
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4019
AB  - Star-shaped polymers of biodegradable aliphatic polyester, poly(ε-caprolactone), PCL, with different number of arms (three, four, and six) were synthesized by ring-opening polymerization initiated by multifunctional alcohols used as cores. As potential biomaterials, synthesized star-shaped poly(ε-caprolactone)s, sPCL, were thoroughly characterized in terms of their degradation under different pH conditions and in respect to their cytotoxicity. The in vitro degradation was performed in phosphate buffer (pH 7.4) and hydrochloric acid solution (pH 1.0) over 5 weeks. Degradation of sPCL films was followed by the weight loss measurements, GPC, FTIR, and AFM analysis. While the most of the samples were stable against the abiotic hydrolysis at pH 7.4 after 5 weeks of degradation, degradation was significantly accelerated in the acidic medium. Degradation rate of polymer films was affected by the polymer architecture and molecular weight. The molecular weight profiles during the degradation revealed random chain scission of the ester bonds indicating bulk degradation mechanism of hydrolysis at pH 7.4, while acidic hydrolysis proceeded through the bulk degradation associated with surface erosion, confirmed by AFM. The in vitro toxicity tests, cytotoxicity applying normal human fibroblasts (MRC5) and embryotoxicity assessment (using zebra fish model, Danio rerio), suggested those polymeric materials as suitable for biomedical application.
PB  - SAGE Publications
T2  - Journal of Bioactive and Compatible Polymers
T1  - Hydrolytic degradation of star-shaped poly(ε-caprolactone)s with different number of arms and their cytotoxic effects
VL  - 35
IS  - 6
SP  - 517
EP  - 537
DO  - 10.1177/0883911520951826
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Stevanović, Sanja and Nikodinović-Runić, Jasmina and Jeremić, Sanja and Pavić, Aleksandar and Đongalić, Jasna",
year = "2020",
abstract = "Star-shaped polymers of biodegradable aliphatic polyester, poly(ε-caprolactone), PCL, with different number of arms (three, four, and six) were synthesized by ring-opening polymerization initiated by multifunctional alcohols used as cores. As potential biomaterials, synthesized star-shaped poly(ε-caprolactone)s, sPCL, were thoroughly characterized in terms of their degradation under different pH conditions and in respect to their cytotoxicity. The in vitro degradation was performed in phosphate buffer (pH 7.4) and hydrochloric acid solution (pH 1.0) over 5 weeks. Degradation of sPCL films was followed by the weight loss measurements, GPC, FTIR, and AFM analysis. While the most of the samples were stable against the abiotic hydrolysis at pH 7.4 after 5 weeks of degradation, degradation was significantly accelerated in the acidic medium. Degradation rate of polymer films was affected by the polymer architecture and molecular weight. The molecular weight profiles during the degradation revealed random chain scission of the ester bonds indicating bulk degradation mechanism of hydrolysis at pH 7.4, while acidic hydrolysis proceeded through the bulk degradation associated with surface erosion, confirmed by AFM. The in vitro toxicity tests, cytotoxicity applying normal human fibroblasts (MRC5) and embryotoxicity assessment (using zebra fish model, Danio rerio), suggested those polymeric materials as suitable for biomedical application.",
publisher = "SAGE Publications",
journal = "Journal of Bioactive and Compatible Polymers",
title = "Hydrolytic degradation of star-shaped poly(ε-caprolactone)s with different number of arms and their cytotoxic effects",
volume = "35",
number = "6",
pages = "517-537",
doi = "10.1177/0883911520951826"
}

Ponjavić, M., Nikolić, M. S., Stevanović, S., Nikodinović-Runić, J., Jeremić, S., Pavić, A.,& Đongalić, J.. (2020). Hydrolytic degradation of star-shaped poly(ε-caprolactone)s with different number of arms and their cytotoxic effects. in Journal of Bioactive and Compatible Polymers
SAGE Publications., 35(6), 517-537.
https://doi.org/10.1177/0883911520951826

Ponjavić M, Nikolić MS, Stevanović S, Nikodinović-Runić J, Jeremić S, Pavić A, Đongalić J. Hydrolytic degradation of star-shaped poly(ε-caprolactone)s with different number of arms and their cytotoxic effects. in Journal of Bioactive and Compatible Polymers. 2020;35(6):517-537.
doi:10.1177/0883911520951826 .

Ponjavić, Marijana, Nikolić, Marija S., Stevanović, Sanja, Nikodinović-Runić, Jasmina, Jeremić, Sanja, Pavić, Aleksandar, Đongalić, Jasna, "Hydrolytic degradation of star-shaped poly(ε-caprolactone)s with different number of arms and their cytotoxic effects" in Journal of Bioactive and Compatible Polymers, 35, no. 6 (2020):517-537,
https://doi.org/10.1177/0883911520951826 . .

TY  - JOUR
AU  - Rusmirović, Jelena
AU  - Rancic, Milica P.
AU  - Pavlović, Vladimir B.
AU  - Rakić, Vesna M.
AU  - Stevanović, Sanja
AU  - Đonlagić, Jasna
AU  - Marinković, Aleksandar D.
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2421
AB  - Unsaturated fatty acid (FA)-modified nanocellulose (m-NC) shows potential application in improving mechanical properties of unsaturated polyester/m-NC nanocomposites (UPe/m-NC). A polyester matrix is obtained by polycondensation of maleic anhydride and products of poly(ethylene terephthalate) depolymerization with propylene glycol. Two methods of NC modification are performed: direct esterification with oleic acid, linseed, or sunflower oil FAs, and esterification/amidation with maleic acid/ethylene diamine (MA/EDA) bridging group followed by amidation with methyl ester of FAs. Increases of stress at break in the ranges from 148.8% to 181.4% and from 155.8% to193.0% for UPe/m-NC composites loaded with 1 wt% of NC modified directly or via MA/EDA cross-linker, respectively, are obtained. Results of the modeling of tensile modulus, by using the Cox-Krenchel model, show good agreement with experimentally obtained data. The effect of FAs' cross-linking capabilities on the dynamic-mechanical and thermal properties of the UPe/m-NC is studied. Cross-linking density, modulus, and T-g of the nanocomposite show appropriate relation with the unsaturation extent/structure of NC modification.
PB  - Wiley
T2  - Macromolecular Materials and Engineering
T1  - Cross-Linkable Modified Nanocellulose/Polyester Resin-Based Composites: Effect of Unsaturated Fatty Acid Nanocellulose Modification on Material Performances
VL  - 303
IS  - 8
DO  - 10.1002/mame.201700648
ER  - 

@article{
author = "Rusmirović, Jelena and Rancic, Milica P. and Pavlović, Vladimir B. and Rakić, Vesna M. and Stevanović, Sanja and Đonlagić, Jasna and Marinković, Aleksandar D.",
year = "2018",
abstract = "Unsaturated fatty acid (FA)-modified nanocellulose (m-NC) shows potential application in improving mechanical properties of unsaturated polyester/m-NC nanocomposites (UPe/m-NC). A polyester matrix is obtained by polycondensation of maleic anhydride and products of poly(ethylene terephthalate) depolymerization with propylene glycol. Two methods of NC modification are performed: direct esterification with oleic acid, linseed, or sunflower oil FAs, and esterification/amidation with maleic acid/ethylene diamine (MA/EDA) bridging group followed by amidation with methyl ester of FAs. Increases of stress at break in the ranges from 148.8% to 181.4% and from 155.8% to193.0% for UPe/m-NC composites loaded with 1 wt% of NC modified directly or via MA/EDA cross-linker, respectively, are obtained. Results of the modeling of tensile modulus, by using the Cox-Krenchel model, show good agreement with experimentally obtained data. The effect of FAs' cross-linking capabilities on the dynamic-mechanical and thermal properties of the UPe/m-NC is studied. Cross-linking density, modulus, and T-g of the nanocomposite show appropriate relation with the unsaturation extent/structure of NC modification.",
publisher = "Wiley",
journal = "Macromolecular Materials and Engineering",
title = "Cross-Linkable Modified Nanocellulose/Polyester Resin-Based Composites: Effect of Unsaturated Fatty Acid Nanocellulose Modification on Material Performances",
volume = "303",
number = "8",
doi = "10.1002/mame.201700648"
}

Rusmirović, J., Rancic, M. P., Pavlović, V. B., Rakić, V. M., Stevanović, S., Đonlagić, J.,& Marinković, A. D.. (2018). Cross-Linkable Modified Nanocellulose/Polyester Resin-Based Composites: Effect of Unsaturated Fatty Acid Nanocellulose Modification on Material Performances. in Macromolecular Materials and Engineering
Wiley., 303(8).
https://doi.org/10.1002/mame.201700648

Rusmirović J, Rancic MP, Pavlović VB, Rakić VM, Stevanović S, Đonlagić J, Marinković AD. Cross-Linkable Modified Nanocellulose/Polyester Resin-Based Composites: Effect of Unsaturated Fatty Acid Nanocellulose Modification on Material Performances. in Macromolecular Materials and Engineering. 2018;303(8).
doi:10.1002/mame.201700648 .

Rusmirović, Jelena, Rancic, Milica P., Pavlović, Vladimir B., Rakić, Vesna M., Stevanović, Sanja, Đonlagić, Jasna, Marinković, Aleksandar D., "Cross-Linkable Modified Nanocellulose/Polyester Resin-Based Composites: Effect of Unsaturated Fatty Acid Nanocellulose Modification on Material Performances" in Macromolecular Materials and Engineering, 303, no. 8 (2018),
https://doi.org/10.1002/mame.201700648 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Jeremić, Sanja
AU  - Đokić, Lidija
AU  - Nikodinović-Runić, Jasmina
AU  - Ćosović, Vladan
AU  - Đonlagić, Jasna
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2311
AB  - Hydrolytic, enzymatic degradation and composting under controlled conditions of series of triblock PCL/PEO copolymers, PCEC, with central short PEO block (M (n) 400 g/mol) are presented and compared with homopolymer (PCL). The PCEC copolymers, synthesized via ring-opening polymerization of epsilon-caprolactone, were characterized by H-1 NMR, quantitative C-13 NMR, GPC, DSC and WAXS. The introduction of the PEO central segment ( LT  2 wt%) in PCL chains significantly affected thermal degradation and crystallization behavior, while the hydrophobicity was slightly reduced as confirmed by water absorption and moisture uptake experiments. Hydrolytic degradation studies in phosphate buffer after 8 weeks indicated a small weight loss, while FTIR analysis detected changes in crystallinity indexes and GPC measurements revealed bulk degradation. Enzymatic degradation tested by cell-free extracts containing Pseudomonas aeruginosa PAO1 confirmed high enzyme activity throughout the surface causing morphological changes detected by optical microscopy and AFM analysis. The changes in roughness of polymer films revealed surface erosion mechanism of enzymatic degradation. Copolymer with the highest content of PEO segment and the lowest molecular weight showed better degradation ability compared to PCL and other copolymers. Furthermore, composting of polymer films in a model compost system at 37 A degrees C resulted in significant degradation of the all synthesized block copolymers.
PB  - Springer
T2  - Journal of Polymers and the Environment
T1  - Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers
VL  - 26
IS  - 6
SP  - 2346
EP  - 2359
DO  - 10.1007/s10924-017-1130-2
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Jeremić, Sanja and Đokić, Lidija and Nikodinović-Runić, Jasmina and Ćosović, Vladan and Đonlagić, Jasna",
year = "2018",
abstract = "Hydrolytic, enzymatic degradation and composting under controlled conditions of series of triblock PCL/PEO copolymers, PCEC, with central short PEO block (M (n) 400 g/mol) are presented and compared with homopolymer (PCL). The PCEC copolymers, synthesized via ring-opening polymerization of epsilon-caprolactone, were characterized by H-1 NMR, quantitative C-13 NMR, GPC, DSC and WAXS. The introduction of the PEO central segment ( LT  2 wt%) in PCL chains significantly affected thermal degradation and crystallization behavior, while the hydrophobicity was slightly reduced as confirmed by water absorption and moisture uptake experiments. Hydrolytic degradation studies in phosphate buffer after 8 weeks indicated a small weight loss, while FTIR analysis detected changes in crystallinity indexes and GPC measurements revealed bulk degradation. Enzymatic degradation tested by cell-free extracts containing Pseudomonas aeruginosa PAO1 confirmed high enzyme activity throughout the surface causing morphological changes detected by optical microscopy and AFM analysis. The changes in roughness of polymer films revealed surface erosion mechanism of enzymatic degradation. Copolymer with the highest content of PEO segment and the lowest molecular weight showed better degradation ability compared to PCL and other copolymers. Furthermore, composting of polymer films in a model compost system at 37 A degrees C resulted in significant degradation of the all synthesized block copolymers.",
publisher = "Springer",
journal = "Journal of Polymers and the Environment",
title = "Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers",
volume = "26",
number = "6",
pages = "2346-2359",
doi = "10.1007/s10924-017-1130-2"
}

Ponjavić, M., Nikolić, M. S., Jeremić, S., Đokić, L., Nikodinović-Runić, J., Ćosović, V.,& Đonlagić, J.. (2018). Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers. in Journal of Polymers and the Environment
Springer., 26(6), 2346-2359.
https://doi.org/10.1007/s10924-017-1130-2

Ponjavić M, Nikolić MS, Jeremić S, Đokić L, Nikodinović-Runić J, Ćosović V, Đonlagić J. Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers. in Journal of Polymers and the Environment. 2018;26(6):2346-2359.
doi:10.1007/s10924-017-1130-2 .

Ponjavić, Marijana, Nikolić, Marija S., Jeremić, Sanja, Đokić, Lidija, Nikodinović-Runić, Jasmina, Ćosović, Vladan, Đonlagić, Jasna, "Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers" in Journal of Polymers and the Environment, 26, no. 6 (2018):2346-2359,
https://doi.org/10.1007/s10924-017-1130-2 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Nikodinović-Runić, Jasmina
AU  - Jeremić, Sanja
AU  - Stevanović, Sanja
AU  - Đonlagić, Jasna
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2200
AB  - Short-term hydrolytic and enzymatic degradation of poly(epsilon-caprolactone) (PCL), one series of triblock (PCL/PEO/PCL) and the other of diblock (PCL/PEO) copolymers, with a low content of hydrophilic PEO segments is presented. The effect of the introduction of PEO as the central or lateral segment in the PCL chain on copolymer hydrolysis and biodegradation properties was investigated. FUR results revealed higher hydrolytic degradation susceptibility of diblock copolymers due to a higher hydrophilicity compared to PCL and triblock copolymers. Enzymatic degradation was tested using cell-free extracts of Pseudomonas aeruginosa PAO1, for two weeks by following the weight loss, changes in surface roughness, and changes in carbonyl and crystallinity index. The results confirmed that all samples underwent enzymatic degradation through surface erosion which was accompanied with a decrease in molecular weights. Diblock copolymers showed significantly higher weight loss and decrease in molecular weight in comparison to PCL itself and triblock copolymers. AFM analysis confirmed significant surface erosion and increase in RMS values. In addition, biodegradation of polymer films was tested in compost model system at 37 degrees C, where an effective degradation of block copolymers was observed.
PB  - Elsevier Sci Ltd, Oxford
T2  - Polymer Testing
T1  - Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions
VL  - 57
SP  - 67
EP  - 77
DO  - 10.1016/j.polymertesting.2016.11.018
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Nikodinović-Runić, Jasmina and Jeremić, Sanja and Stevanović, Sanja and Đonlagić, Jasna",
year = "2017",
abstract = "Short-term hydrolytic and enzymatic degradation of poly(epsilon-caprolactone) (PCL), one series of triblock (PCL/PEO/PCL) and the other of diblock (PCL/PEO) copolymers, with a low content of hydrophilic PEO segments is presented. The effect of the introduction of PEO as the central or lateral segment in the PCL chain on copolymer hydrolysis and biodegradation properties was investigated. FUR results revealed higher hydrolytic degradation susceptibility of diblock copolymers due to a higher hydrophilicity compared to PCL and triblock copolymers. Enzymatic degradation was tested using cell-free extracts of Pseudomonas aeruginosa PAO1, for two weeks by following the weight loss, changes in surface roughness, and changes in carbonyl and crystallinity index. The results confirmed that all samples underwent enzymatic degradation through surface erosion which was accompanied with a decrease in molecular weights. Diblock copolymers showed significantly higher weight loss and decrease in molecular weight in comparison to PCL itself and triblock copolymers. AFM analysis confirmed significant surface erosion and increase in RMS values. In addition, biodegradation of polymer films was tested in compost model system at 37 degrees C, where an effective degradation of block copolymers was observed.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Polymer Testing",
title = "Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions",
volume = "57",
pages = "67-77",
doi = "10.1016/j.polymertesting.2016.11.018"
}

Ponjavić, M., Nikolić, M. S., Nikodinović-Runić, J., Jeremić, S., Stevanović, S.,& Đonlagić, J.. (2017). Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions. in Polymer Testing
Elsevier Sci Ltd, Oxford., 57, 67-77.
https://doi.org/10.1016/j.polymertesting.2016.11.018

Ponjavić M, Nikolić MS, Nikodinović-Runić J, Jeremić S, Stevanović S, Đonlagić J. Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions. in Polymer Testing. 2017;57:67-77.
doi:10.1016/j.polymertesting.2016.11.018 .

Ponjavić, Marijana, Nikolić, Marija S., Nikodinović-Runić, Jasmina, Jeremić, Sanja, Stevanović, Sanja, Đonlagić, Jasna, "Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions" in Polymer Testing, 57 (2017):67-77,
https://doi.org/10.1016/j.polymertesting.2016.11.018 . .

TY  - JOUR
AU  - Nikolić, Marija S.
AU  - Petrovic, Rada
AU  - Veljović, Đorđe
AU  - Ćosović, Vladan
AU  - Stankovic, Nadezda
AU  - Đonlagić, Jasna
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2104
AB  - Poly(epsilon-caprolactone) (PCL) based nanocomposites with unmodified and organomodified sepiolites were prepared by solution casting method. The sepiolites were modified with short (3-mercaptopropyl)trimethoxysilane (SEP-SI) by using covalent grafting or with long hexadecylamine (SEP-HDA) by using ionic exchange. In order to reveal the influence of the organomodification on the nanoclay dispersion and the properties of the nano composites XRD, DSC, TG, SEM, TEM, optical microscopy, melt rheology and dynamic-mechanical analyses were performed. A better dispersion was achieved when organomodified sepiolites instead of native ones were used as fillers. As deduced from the melt rheology data, by analysis of the Cole-Cole plots, the best dispersion was obtained for SEP-SI nanoclay. The thermal stability was not improved, however in the initial stages of the thereto-oxidative degradation a delay in the weight loss was observed for nanocomposites with organomodified sepiolites. The mechanical properties of the nanocomposites were improved in comparison to PCL, particularly for those with modified sepiolites. In terms of mechanical properties the use of sepiolite modified with HDA gave the best results, as a consequence of better interaction between longer alkyl hydrophobic part of the organic modificator and the hydrophobic PCL matrix.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - European Polymer Journal
T1  - Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites
VL  - 97
SP  - 198
EP  - 209
DO  - 10.1016/j.eurpolymj.2017.10.010
ER  - 

@article{
author = "Nikolić, Marija S. and Petrovic, Rada and Veljović, Đorđe and Ćosović, Vladan and Stankovic, Nadezda and Đonlagić, Jasna",
year = "2017",
abstract = "Poly(epsilon-caprolactone) (PCL) based nanocomposites with unmodified and organomodified sepiolites were prepared by solution casting method. The sepiolites were modified with short (3-mercaptopropyl)trimethoxysilane (SEP-SI) by using covalent grafting or with long hexadecylamine (SEP-HDA) by using ionic exchange. In order to reveal the influence of the organomodification on the nanoclay dispersion and the properties of the nano composites XRD, DSC, TG, SEM, TEM, optical microscopy, melt rheology and dynamic-mechanical analyses were performed. A better dispersion was achieved when organomodified sepiolites instead of native ones were used as fillers. As deduced from the melt rheology data, by analysis of the Cole-Cole plots, the best dispersion was obtained for SEP-SI nanoclay. The thermal stability was not improved, however in the initial stages of the thereto-oxidative degradation a delay in the weight loss was observed for nanocomposites with organomodified sepiolites. The mechanical properties of the nanocomposites were improved in comparison to PCL, particularly for those with modified sepiolites. In terms of mechanical properties the use of sepiolite modified with HDA gave the best results, as a consequence of better interaction between longer alkyl hydrophobic part of the organic modificator and the hydrophobic PCL matrix.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "European Polymer Journal",
title = "Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites",
volume = "97",
pages = "198-209",
doi = "10.1016/j.eurpolymj.2017.10.010"
}

Nikolić, M. S., Petrovic, R., Veljović, Đ., Ćosović, V., Stankovic, N.,& Đonlagić, J.. (2017). Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites. in European Polymer Journal
Oxford : Pergamon-Elsevier Science Ltd., 97, 198-209.
https://doi.org/10.1016/j.eurpolymj.2017.10.010

Nikolić MS, Petrovic R, Veljović Đ, Ćosović V, Stankovic N, Đonlagić J. Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites. in European Polymer Journal. 2017;97:198-209.
doi:10.1016/j.eurpolymj.2017.10.010 .

Nikolić, Marija S., Petrovic, Rada, Veljović, Đorđe, Ćosović, Vladan, Stankovic, Nadezda, Đonlagić, Jasna, "Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites" in European Polymer Journal, 97 (2017):198-209,
https://doi.org/10.1016/j.eurpolymj.2017.10.010 . .

TY  - JOUR
AU  - Nikolić, Marija S.
AU  - Petrovic, Rada
AU  - Veljović, Đorđe
AU  - Ćosović, Vladan
AU  - Stankovic, Nadezda
AU  - Đonlagić, Jasna
PY  - 2017
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2941
AB  - Poly(epsilon-caprolactone) (PCL) based nanocomposites with unmodified and organomodified sepiolites were prepared by solution casting method. The sepiolites were modified with short (3-mercaptopropyl)trimethoxysilane (SEP-SI) by using covalent grafting or with long hexadecylamine (SEP-HDA) by using ionic exchange. In order to reveal the influence of the organomodification on the nanoclay dispersion and the properties of the nano composites XRD, DSC, TG, SEM, TEM, optical microscopy, melt rheology and dynamic-mechanical analyses were performed. A better dispersion was achieved when organomodified sepiolites instead of native ones were used as fillers. As deduced from the melt rheology data, by analysis of the Cole-Cole plots, the best dispersion was obtained for SEP-SI nanoclay. The thermal stability was not improved, however in the initial stages of the thereto-oxidative degradation a delay in the weight loss was observed for nanocomposites with organomodified sepiolites. The mechanical properties of the nanocomposites were improved in comparison to PCL, particularly for those with modified sepiolites. In terms of mechanical properties the use of sepiolite modified with HDA gave the best results, as a consequence of better interaction between longer alkyl hydrophobic part of the organic modificator and the hydrophobic PCL matrix.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - European Polymer Journal
T1  - Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites
VL  - 97
SP  - 198
EP  - 209
DO  - 10.1016/j.eurpolymj.2017.10.010
ER  - 

@article{
author = "Nikolić, Marija S. and Petrovic, Rada and Veljović, Đorđe and Ćosović, Vladan and Stankovic, Nadezda and Đonlagić, Jasna",
year = "2017",
abstract = "Poly(epsilon-caprolactone) (PCL) based nanocomposites with unmodified and organomodified sepiolites were prepared by solution casting method. The sepiolites were modified with short (3-mercaptopropyl)trimethoxysilane (SEP-SI) by using covalent grafting or with long hexadecylamine (SEP-HDA) by using ionic exchange. In order to reveal the influence of the organomodification on the nanoclay dispersion and the properties of the nano composites XRD, DSC, TG, SEM, TEM, optical microscopy, melt rheology and dynamic-mechanical analyses were performed. A better dispersion was achieved when organomodified sepiolites instead of native ones were used as fillers. As deduced from the melt rheology data, by analysis of the Cole-Cole plots, the best dispersion was obtained for SEP-SI nanoclay. The thermal stability was not improved, however in the initial stages of the thereto-oxidative degradation a delay in the weight loss was observed for nanocomposites with organomodified sepiolites. The mechanical properties of the nanocomposites were improved in comparison to PCL, particularly for those with modified sepiolites. In terms of mechanical properties the use of sepiolite modified with HDA gave the best results, as a consequence of better interaction between longer alkyl hydrophobic part of the organic modificator and the hydrophobic PCL matrix.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "European Polymer Journal",
title = "Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites",
volume = "97",
pages = "198-209",
doi = "10.1016/j.eurpolymj.2017.10.010"
}

Nikolić, M. S., Petrovic, R., Veljović, Đ., Ćosović, V., Stankovic, N.,& Đonlagić, J.. (2017). Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites. in European Polymer Journal
Oxford : Pergamon-Elsevier Science Ltd., 97, 198-209.
https://doi.org/10.1016/j.eurpolymj.2017.10.010

Nikolić MS, Petrovic R, Veljović Đ, Ćosović V, Stankovic N, Đonlagić J. Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites. in European Polymer Journal. 2017;97:198-209.
doi:10.1016/j.eurpolymj.2017.10.010 .

Nikolić, Marija S., Petrovic, Rada, Veljović, Đorđe, Ćosović, Vladan, Stankovic, Nadezda, Đonlagić, Jasna, "Effect of sepiolite organomodification on the performance of PCL/sepiolite nanocomposites" in European Polymer Journal, 97 (2017):198-209,
https://doi.org/10.1016/j.eurpolymj.2017.10.010 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Jevtic, Sanja
AU  - Rogan, Jelena R.
AU  - Stevanović, Sanja
AU  - Đonlagić, Jasna
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2003
AB  - Two series, one of triblock (PCL/PEO/PCL) and the other of diblock (PCL/PEO) copolymers were prepared by ring-opening polymerization of epsilon-caprolactone catalized with tin(II) octoate and by using dihydroxy or monohydroxy poly(ethylene oxide) as the macroinitiator. The PEO block length was fixed (M-n 1,000 g/mol) and the PCL block lengths (M-n 10,000-40,000 g/mol) were tailored by changing weight ratio of epsilon-CL/PEO. The copolymers' structure was confirmed by H-1 and quantitative C-13 NMR spectroscopy while their molecular weights were determined by GPC analysis. The thermal properties and the degree of crystallinity of the copolymers were investigated and compared by using DSC and WAXS. Both types of copolymers were semicrystalline with the orthorhombic PCL crystal lattice. The surface morphology of the copolymer films was investigated by using optical microscopy and AFM analysis, which confirmed the spherulitic lamellar structure with spherulites of different diameters. Data indicated that a low content of PEO segment had an influence on thermal degradation behavior, crystallinity and morphology of copolymers. Roughness of copolymer films was affected by the content of PEO and correlated with the spherulites' diameter. The small changes in water and moisture absorption properties of copolymers compared to homopolymer PCL were observed.
PB  - Springer, Dordrecht
T2  - Macromolecular Research
T1  - Influence of a Low Content of PEO Segment on the Thermal, Surface and Morphological Properties of Triblock and Diblock PCL Copolymers
VL  - 24
IS  - 4
SP  - 323
EP  - 335
DO  - 10.1007/s13233-016-4048-y
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Jevtic, Sanja and Rogan, Jelena R. and Stevanović, Sanja and Đonlagić, Jasna",
year = "2016",
abstract = "Two series, one of triblock (PCL/PEO/PCL) and the other of diblock (PCL/PEO) copolymers were prepared by ring-opening polymerization of epsilon-caprolactone catalized with tin(II) octoate and by using dihydroxy or monohydroxy poly(ethylene oxide) as the macroinitiator. The PEO block length was fixed (M-n 1,000 g/mol) and the PCL block lengths (M-n 10,000-40,000 g/mol) were tailored by changing weight ratio of epsilon-CL/PEO. The copolymers' structure was confirmed by H-1 and quantitative C-13 NMR spectroscopy while their molecular weights were determined by GPC analysis. The thermal properties and the degree of crystallinity of the copolymers were investigated and compared by using DSC and WAXS. Both types of copolymers were semicrystalline with the orthorhombic PCL crystal lattice. The surface morphology of the copolymer films was investigated by using optical microscopy and AFM analysis, which confirmed the spherulitic lamellar structure with spherulites of different diameters. Data indicated that a low content of PEO segment had an influence on thermal degradation behavior, crystallinity and morphology of copolymers. Roughness of copolymer films was affected by the content of PEO and correlated with the spherulites' diameter. The small changes in water and moisture absorption properties of copolymers compared to homopolymer PCL were observed.",
publisher = "Springer, Dordrecht",
journal = "Macromolecular Research",
title = "Influence of a Low Content of PEO Segment on the Thermal, Surface and Morphological Properties of Triblock and Diblock PCL Copolymers",
volume = "24",
number = "4",
pages = "323-335",
doi = "10.1007/s13233-016-4048-y"
}

Ponjavić, M., Nikolić, M. S., Jevtic, S., Rogan, J. R., Stevanović, S.,& Đonlagić, J.. (2016). Influence of a Low Content of PEO Segment on the Thermal, Surface and Morphological Properties of Triblock and Diblock PCL Copolymers. in Macromolecular Research
Springer, Dordrecht., 24(4), 323-335.
https://doi.org/10.1007/s13233-016-4048-y

Ponjavić M, Nikolić MS, Jevtic S, Rogan JR, Stevanović S, Đonlagić J. Influence of a Low Content of PEO Segment on the Thermal, Surface and Morphological Properties of Triblock and Diblock PCL Copolymers. in Macromolecular Research. 2016;24(4):323-335.
doi:10.1007/s13233-016-4048-y .

Ponjavić, Marijana, Nikolić, Marija S., Jevtic, Sanja, Rogan, Jelena R., Stevanović, Sanja, Đonlagić, Jasna, "Influence of a Low Content of PEO Segment on the Thermal, Surface and Morphological Properties of Triblock and Diblock PCL Copolymers" in Macromolecular Research, 24, no. 4 (2016):323-335,
https://doi.org/10.1007/s13233-016-4048-y . .

TY  - JOUR
AU  - Stefanović, Ivan
AU  - Đonlagić, Jasna
AU  - Tovilović, Gordana
AU  - Nestorov, Jelena
AU  - Antić, Vesna
AU  - Ostojić, Sanja
AU  - Pergal, Marija
PY  - 2015
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1779
AB  - Polyurethane copolymers based on ,-dihydroxypropyl poly(dimethylsiloxane) (PDMS) with a range of soft segment contents were prepared by two-stage polymerization, and their microstructures, thermal, thermomechanical, and surface properties, as well as in vitro hemo- and cytocompatibility were evaluated. All utilized characterization methods confirmed the existence of moderately microphase separated structures with the appearance of some microphase mixing between segments as the PDMS (i.e., soft segment) content increased. Copolymers showed higher crystallinity, storage moduli, surface roughness, and surface free energy, but less hydrophobicity with decreasing PDMS content. Biocompatibility of copolymers was evaluated using an endothelial EA.hy926 cell line by direct contact, an extraction method and after pretreatment of copolymers with multicomponent protein mixture, as well as by a competitive protein adsorption assay. Copolymers showed no toxic effect to endothelial cells and all copolymers, except that with the lowest PDMS content, exhibited resistance to endothelial cell adhesion, suggesting their unsuitability for long-term biomedical devices which particularly require re-endothelialization. All copolymers exhibited excellent resistance to fibrinogen adsorption and adsorbed more albumin than fibrinogen in the competitive adsorption assay, suggesting their good hemocompatibility. The noncytotoxic chemistry of these synthesized materials, combined with their nonadherent properties which are inhospitable to cell attachment and growth, underlie the need for further investigations to clarify their potential for use in short-term biomedical devices.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Biomedical Materials Research Part A
T1  - Poly(urethane-dimethylsiloxane) copolymers displaying a range of soft segment contents, noncytotoxic chemistry, and nonadherent properties toward endothelial cells
VL  - 103
IS  - 4
SP  - 1459
EP  - 1475
DO  - 10.1002/jbm.a.35285
ER  - 

@article{
author = "Stefanović, Ivan and Đonlagić, Jasna and Tovilović, Gordana and Nestorov, Jelena and Antić, Vesna and Ostojić, Sanja and Pergal, Marija",
year = "2015",
abstract = "Polyurethane copolymers based on ,-dihydroxypropyl poly(dimethylsiloxane) (PDMS) with a range of soft segment contents were prepared by two-stage polymerization, and their microstructures, thermal, thermomechanical, and surface properties, as well as in vitro hemo- and cytocompatibility were evaluated. All utilized characterization methods confirmed the existence of moderately microphase separated structures with the appearance of some microphase mixing between segments as the PDMS (i.e., soft segment) content increased. Copolymers showed higher crystallinity, storage moduli, surface roughness, and surface free energy, but less hydrophobicity with decreasing PDMS content. Biocompatibility of copolymers was evaluated using an endothelial EA.hy926 cell line by direct contact, an extraction method and after pretreatment of copolymers with multicomponent protein mixture, as well as by a competitive protein adsorption assay. Copolymers showed no toxic effect to endothelial cells and all copolymers, except that with the lowest PDMS content, exhibited resistance to endothelial cell adhesion, suggesting their unsuitability for long-term biomedical devices which particularly require re-endothelialization. All copolymers exhibited excellent resistance to fibrinogen adsorption and adsorbed more albumin than fibrinogen in the competitive adsorption assay, suggesting their good hemocompatibility. The noncytotoxic chemistry of these synthesized materials, combined with their nonadherent properties which are inhospitable to cell attachment and growth, underlie the need for further investigations to clarify their potential for use in short-term biomedical devices.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Biomedical Materials Research Part A",
title = "Poly(urethane-dimethylsiloxane) copolymers displaying a range of soft segment contents, noncytotoxic chemistry, and nonadherent properties toward endothelial cells",
volume = "103",
number = "4",
pages = "1459-1475",
doi = "10.1002/jbm.a.35285"
}

Stefanović, I., Đonlagić, J., Tovilović, G., Nestorov, J., Antić, V., Ostojić, S.,& Pergal, M.. (2015). Poly(urethane-dimethylsiloxane) copolymers displaying a range of soft segment contents, noncytotoxic chemistry, and nonadherent properties toward endothelial cells. in Journal of Biomedical Materials Research Part A
Wiley-Blackwell, Hoboken., 103(4), 1459-1475.
https://doi.org/10.1002/jbm.a.35285

Stefanović I, Đonlagić J, Tovilović G, Nestorov J, Antić V, Ostojić S, Pergal M. Poly(urethane-dimethylsiloxane) copolymers displaying a range of soft segment contents, noncytotoxic chemistry, and nonadherent properties toward endothelial cells. in Journal of Biomedical Materials Research Part A. 2015;103(4):1459-1475.
doi:10.1002/jbm.a.35285 .

Stefanović, Ivan, Đonlagić, Jasna, Tovilović, Gordana, Nestorov, Jelena, Antić, Vesna, Ostojić, Sanja, Pergal, Marija, "Poly(urethane-dimethylsiloxane) copolymers displaying a range of soft segment contents, noncytotoxic chemistry, and nonadherent properties toward endothelial cells" in Journal of Biomedical Materials Research Part A, 103, no. 4 (2015):1459-1475,
https://doi.org/10.1002/jbm.a.35285 . .

TY  - JOUR
AU  - Pergal, Marija
AU  - Nestorov, Jelena
AU  - Tovilović, Gordana
AU  - Ostojić, Sanja
AU  - Gođevac, Dejan
AU  - Vasiljević-Radović, Dana
AU  - Đonlagić, Jasna
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1398
AB  - Properties and biocompatibility of a series of thermoplastic poly(urethane-siloxane)s (TPUSs) based on alpha,omega-dihydroxy ethoxy propyl poly(dimethylsiloxane) (PDMS) for potential biomedical application were studied. Thin films of TPUSs with a different PDMS soft segment content were characterized by H-1 NMR, quantitative C-13 NMR, Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), contact angle, and water absorption measurements. Different techniques (FTIR, AFM, and DMA) showed that decrease of PDMS content promotes microphase separation in TPUSs. Samples with a higher PDMS content have more hydrophobic surface and better waterproof performances, but lower degree of crystallinity. Biocompatibility of TPUSs was examined after attachment of endothelial cells to the untreated copolymer surface or surface pretreated with multicomponent protein mixture, and by using competitive protein adsorption assay. TPUSs did not exhibit any cytotoxicity toward endothelial cells, as measured by lactate dehydrogenase and 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide assays. The untreated and proteins preadsorbed TPUS samples favored endothelial cells adhesion and growth, indicating good biocompatibility. All TPUSs adsorbed more albumin than fibrinogen in competitive protein adsorption experiment, which is feature regarded as beneficial for biocompatibility. The results indicate that TPUSs have good surface, thermo-mechanical, and biocompatible properties, which can be tailored for biomedical application requirements by adequate selection of the soft/hard segments ratio of the copolymers.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Biomedical Materials Research Part A
T1  - Structure and properties of thermoplastic polyurethanes based on poly(dimethylsiloxane): Assessment of biocompatibility
VL  - 102
IS  - 11
SP  - 3951
EP  - 3964
DO  - 10.1002/jbm.a.35071
ER  - 

@article{
author = "Pergal, Marija and Nestorov, Jelena and Tovilović, Gordana and Ostojić, Sanja and Gođevac, Dejan and Vasiljević-Radović, Dana and Đonlagić, Jasna",
year = "2014",
abstract = "Properties and biocompatibility of a series of thermoplastic poly(urethane-siloxane)s (TPUSs) based on alpha,omega-dihydroxy ethoxy propyl poly(dimethylsiloxane) (PDMS) for potential biomedical application were studied. Thin films of TPUSs with a different PDMS soft segment content were characterized by H-1 NMR, quantitative C-13 NMR, Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), contact angle, and water absorption measurements. Different techniques (FTIR, AFM, and DMA) showed that decrease of PDMS content promotes microphase separation in TPUSs. Samples with a higher PDMS content have more hydrophobic surface and better waterproof performances, but lower degree of crystallinity. Biocompatibility of TPUSs was examined after attachment of endothelial cells to the untreated copolymer surface or surface pretreated with multicomponent protein mixture, and by using competitive protein adsorption assay. TPUSs did not exhibit any cytotoxicity toward endothelial cells, as measured by lactate dehydrogenase and 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide assays. The untreated and proteins preadsorbed TPUS samples favored endothelial cells adhesion and growth, indicating good biocompatibility. All TPUSs adsorbed more albumin than fibrinogen in competitive protein adsorption experiment, which is feature regarded as beneficial for biocompatibility. The results indicate that TPUSs have good surface, thermo-mechanical, and biocompatible properties, which can be tailored for biomedical application requirements by adequate selection of the soft/hard segments ratio of the copolymers.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Biomedical Materials Research Part A",
title = "Structure and properties of thermoplastic polyurethanes based on poly(dimethylsiloxane): Assessment of biocompatibility",
volume = "102",
number = "11",
pages = "3951-3964",
doi = "10.1002/jbm.a.35071"
}

Pergal, M., Nestorov, J., Tovilović, G., Ostojić, S., Gođevac, D., Vasiljević-Radović, D.,& Đonlagić, J.. (2014). Structure and properties of thermoplastic polyurethanes based on poly(dimethylsiloxane): Assessment of biocompatibility. in Journal of Biomedical Materials Research Part A
Wiley-Blackwell, Hoboken., 102(11), 3951-3964.
https://doi.org/10.1002/jbm.a.35071

Pergal M, Nestorov J, Tovilović G, Ostojić S, Gođevac D, Vasiljević-Radović D, Đonlagić J. Structure and properties of thermoplastic polyurethanes based on poly(dimethylsiloxane): Assessment of biocompatibility. in Journal of Biomedical Materials Research Part A. 2014;102(11):3951-3964.
doi:10.1002/jbm.a.35071 .

Pergal, Marija, Nestorov, Jelena, Tovilović, Gordana, Ostojić, Sanja, Gođevac, Dejan, Vasiljević-Radović, Dana, Đonlagić, Jasna, "Structure and properties of thermoplastic polyurethanes based on poly(dimethylsiloxane): Assessment of biocompatibility" in Journal of Biomedical Materials Research Part A, 102, no. 11 (2014):3951-3964,
https://doi.org/10.1002/jbm.a.35071 . .

TY  - JOUR
AU  - Pergal, Marija
AU  - Nestorov, Jelena
AU  - Tovilović-Kovačević, Gordana
AU  - Jovančić, Petar
AU  - Pezo, Lato
AU  - Vasiljević-Radović, Dana
AU  - Đonlagić, Jasna
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1456
AB  - Segmented polyurethanes based on poly(dimethylsiloxane), currently used for biomedical applications, have sub-optimal biocompatibility which reduces their efficacy. Improving the endothelial cell attachment and blood-contacting properties of PDMS-based copolymers would substantially improve their clinical applications. We have studied the surface properties and in vitro biocompatibility of two series of segmented poly(urethane-dimethylsiloxane)s (SPU-PDMS) based on hydroxypropyl- and hydroxyethoxypropyl-terminated PDMS with potential applications in blood-contacting medical devices. SPU-PDMS copolymers were characterized by contact angle measurements, surface free energy determination (calculated using the van Oss-Chaudhury-Good and Owens-Wendt methods), and atomic force microscopy. The biocompatibility of copolymers was evaluated using an endothelial EA.hy926 cell line by direct contact assay, before and after pre-treatment of copolymers with multicomponent protein mixture, as well as by a competitive blood-protein adsorption assay. The obtained results suggested good blood compatibility of synthesized copolymers. All copolymers exhibited good resistance to fibrinogen adsorption and all favored albumin adsorption. Copolymers based on hydroxyethoxypropyl-PDMS had lower hydrophobicity, higher surface free energy and better microphase separation in comparison with hydroxypropyl-PDMS-based copolymers, which promoted better endothelial cell attachment and growth on the surface of these polymers as compared to hydroxypropyl-PDMS-based copolymers. The results showed that SPU-PDMS copolymers display good surface properties, depending on the type of soft PDMS segments, which can be tailored for biomedical application requirements such as biomedical devices for short- and long-term uses.
AB  - Segmentirani poliuretani na bazi poli(dimetilsiloksana), koji se trenutno koriste u biomedicini, imaju biokompatibilnost ispod optimalne što smanjuje njihovu efikasnost. Poboljšavajući vezivanje endotelnih ćelija i svojstva kopolimera na bazi PDMS u dodiru sa krvlju značajno bi se poboljšala i proširila njihova klinička primena. U ovom radu su proučavana površinska svojstva i in vitro biokompatibilnost dve serije segmentiranih poli(uretan-dimetilsiloksana) (SPU-PDMS) na bazi hidroksipropil- i hidroksietoksipropil- PDMS pretpolimera sa potencijalnim primenama u medicinskim uredjajima u kontaktu sa krvlju. SPU-PDMS kopolimeri su karakterisani merenjem kontaktnih uglova, određivanjem površinske energije (izračunate prema van Oss-Chaudhury-Good i Owens-Wendt metodama), i mikroskopijom atomskih sila. Biokompatibilnost kopolimera je ispitivana primenom endotelnih EA.hy926 ćelija u direktnom kontaktu, pre i nakon pretretiranja kopolimera sa višekomponentnom smešom proteina, kao i pomoću kompetitivne adsorpcije proteina. Dobijeni rezultati su potvrdili da sintetisani kopolimeri imaju dobru kompatibilnost prema krvi. Svi sintetisani kopolimeri pokazivali su dobru otpornost prema adsorpciji fibrinogena i svi kopolimeri su favorizovali adsorpciju albumina. Kopolimeri na bazi hidroksietoksipropil-PDMS imali su manju hidrofobnost, veću površinsku energiju, i bolju mikrofaznu separaciju u poređenju sa kopolimerima na bazi hidroksipropil-PDMS, što je dovelo do boljeg vezivanja i rasta endotelnih ćelija na površini ovih polimera u poređenju sa kopolimerima na bazi hidroksipropil-PDMS. Rezultati su pokazali da SPU-PDMS kopolimeri prikazuju dobra površinska svojstva, zavisno od vrste mekih PDMS segmenata, koja se mogu prilagođavati zahtevima u biomedicini, kao što su biomedicinski uređaji za kratkoročnu i dugoročnu upotrebu.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Surface characterization, hemo- and cytocompatibility of segmented poly(dimethylsiloxane)-based polyurethanes
T1  - Površinska karakterizacija, hemo- i citokompatibilnost segmentiranih poliuretana na bazi poli(dimetilsiloksana)
VL  - 68
IS  - 6
SP  - 731
EP  - 741
DO  - 10.2298/HEMIND141103082P
ER  - 

@article{
author = "Pergal, Marija and Nestorov, Jelena and Tovilović-Kovačević, Gordana and Jovančić, Petar and Pezo, Lato and Vasiljević-Radović, Dana and Đonlagić, Jasna",
year = "2014",
abstract = "Segmented polyurethanes based on poly(dimethylsiloxane), currently used for biomedical applications, have sub-optimal biocompatibility which reduces their efficacy. Improving the endothelial cell attachment and blood-contacting properties of PDMS-based copolymers would substantially improve their clinical applications. We have studied the surface properties and in vitro biocompatibility of two series of segmented poly(urethane-dimethylsiloxane)s (SPU-PDMS) based on hydroxypropyl- and hydroxyethoxypropyl-terminated PDMS with potential applications in blood-contacting medical devices. SPU-PDMS copolymers were characterized by contact angle measurements, surface free energy determination (calculated using the van Oss-Chaudhury-Good and Owens-Wendt methods), and atomic force microscopy. The biocompatibility of copolymers was evaluated using an endothelial EA.hy926 cell line by direct contact assay, before and after pre-treatment of copolymers with multicomponent protein mixture, as well as by a competitive blood-protein adsorption assay. The obtained results suggested good blood compatibility of synthesized copolymers. All copolymers exhibited good resistance to fibrinogen adsorption and all favored albumin adsorption. Copolymers based on hydroxyethoxypropyl-PDMS had lower hydrophobicity, higher surface free energy and better microphase separation in comparison with hydroxypropyl-PDMS-based copolymers, which promoted better endothelial cell attachment and growth on the surface of these polymers as compared to hydroxypropyl-PDMS-based copolymers. The results showed that SPU-PDMS copolymers display good surface properties, depending on the type of soft PDMS segments, which can be tailored for biomedical application requirements such as biomedical devices for short- and long-term uses., Segmentirani poliuretani na bazi poli(dimetilsiloksana), koji se trenutno koriste u biomedicini, imaju biokompatibilnost ispod optimalne što smanjuje njihovu efikasnost. Poboljšavajući vezivanje endotelnih ćelija i svojstva kopolimera na bazi PDMS u dodiru sa krvlju značajno bi se poboljšala i proširila njihova klinička primena. U ovom radu su proučavana površinska svojstva i in vitro biokompatibilnost dve serije segmentiranih poli(uretan-dimetilsiloksana) (SPU-PDMS) na bazi hidroksipropil- i hidroksietoksipropil- PDMS pretpolimera sa potencijalnim primenama u medicinskim uredjajima u kontaktu sa krvlju. SPU-PDMS kopolimeri su karakterisani merenjem kontaktnih uglova, određivanjem površinske energije (izračunate prema van Oss-Chaudhury-Good i Owens-Wendt metodama), i mikroskopijom atomskih sila. Biokompatibilnost kopolimera je ispitivana primenom endotelnih EA.hy926 ćelija u direktnom kontaktu, pre i nakon pretretiranja kopolimera sa višekomponentnom smešom proteina, kao i pomoću kompetitivne adsorpcije proteina. Dobijeni rezultati su potvrdili da sintetisani kopolimeri imaju dobru kompatibilnost prema krvi. Svi sintetisani kopolimeri pokazivali su dobru otpornost prema adsorpciji fibrinogena i svi kopolimeri su favorizovali adsorpciju albumina. Kopolimeri na bazi hidroksietoksipropil-PDMS imali su manju hidrofobnost, veću površinsku energiju, i bolju mikrofaznu separaciju u poređenju sa kopolimerima na bazi hidroksipropil-PDMS, što je dovelo do boljeg vezivanja i rasta endotelnih ćelija na površini ovih polimera u poređenju sa kopolimerima na bazi hidroksipropil-PDMS. Rezultati su pokazali da SPU-PDMS kopolimeri prikazuju dobra površinska svojstva, zavisno od vrste mekih PDMS segmenata, koja se mogu prilagođavati zahtevima u biomedicini, kao što su biomedicinski uređaji za kratkoročnu i dugoročnu upotrebu.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Surface characterization, hemo- and cytocompatibility of segmented poly(dimethylsiloxane)-based polyurethanes, Površinska karakterizacija, hemo- i citokompatibilnost segmentiranih poliuretana na bazi poli(dimetilsiloksana)",
volume = "68",
number = "6",
pages = "731-741",
doi = "10.2298/HEMIND141103082P"
}

Pergal, M., Nestorov, J., Tovilović-Kovačević, G., Jovančić, P., Pezo, L., Vasiljević-Radović, D.,& Đonlagić, J.. (2014). Surface characterization, hemo- and cytocompatibility of segmented poly(dimethylsiloxane)-based polyurethanes. in Hemijska industrija
Association of Chemical Engineers of Serbia., 68(6), 731-741.
https://doi.org/10.2298/HEMIND141103082P

Pergal M, Nestorov J, Tovilović-Kovačević G, Jovančić P, Pezo L, Vasiljević-Radović D, Đonlagić J. Surface characterization, hemo- and cytocompatibility of segmented poly(dimethylsiloxane)-based polyurethanes. in Hemijska industrija. 2014;68(6):731-741.
doi:10.2298/HEMIND141103082P .

Pergal, Marija, Nestorov, Jelena, Tovilović-Kovačević, Gordana, Jovančić, Petar, Pezo, Lato, Vasiljević-Radović, Dana, Đonlagić, Jasna, "Surface characterization, hemo- and cytocompatibility of segmented poly(dimethylsiloxane)-based polyurethanes" in Hemijska industrija, 68, no. 6 (2014):731-741,
https://doi.org/10.2298/HEMIND141103082P . .

TY  - JOUR
AU  - Pergal, Marija
AU  - Stefanović, Ivan
AU  - Gođevac, Dejan
AU  - Antić, Vesna
AU  - Milačić, Vesna
AU  - Ostojić, Sanja
AU  - Rogan, Jelena R.
AU  - Đonlagić, Jasna
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1561
AB  - In this study, the synthesis, structure and physical properties of two series of thermoplastic polyurethanes based on hydroxypropyl-terminated poly(dimethylsiloxane) (HP-PDMS) or hydroxyethoxypropyl-terminated poly(dimethylsiloxane) (EO-PDMS) as soft segments, and 4,4'-methylenediphenyl diisocyanate and 1,4-butanediol as hard segments were investigated. The polyurethanes were synthesized by two-step polyaddition in solution. The effects of the type and content of PDMS segments on the structure, thermal and surface properties of copolymers were studied by H-1-, C-13-nuclear magnetic resonance (NMR) spectroscopy and two-dimensional NMR spectroscopies (heteronuclear multiple bond correlation (HMBC) and rotating-frame nuclear Overhauser effect (ROESY)), gel permeation chromatography (GPC), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), wide-angle X-ray scattering (WAXS), scanning electron microscopy (SEM) and water contact angle and water absorption measurements. Thermal properties investigated by DSC indicated that the presence of soft PDMS segments lowers the glass transition and melting temperatures of the hard phase as well as the degree of crystallinity. SEM analysis of the copolymers with a lower soft segment content confirmed the presence of spherulite superstructures, which arise from the crystallization of the hard segments. When compared with polyurethanes prepared from HP-PDMS, the copolymers synthesized from EO-PDMS with the same content of the soft segments had a higher degree of crystallinity, better thermal stability and a less hydrophobic surface. The obtained results showed that the synthesized polyurethanes had good thermal and surface properties, which could be further modified by changing the type or content of the soft segments.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane)
VL  - 79
IS  - 7
SP  - 843
DO  - 10.2298/JSC130819149P
ER  - 

@article{
author = "Pergal, Marija and Stefanović, Ivan and Gođevac, Dejan and Antić, Vesna and Milačić, Vesna and Ostojić, Sanja and Rogan, Jelena R. and Đonlagić, Jasna",
year = "2014",
abstract = "In this study, the synthesis, structure and physical properties of two series of thermoplastic polyurethanes based on hydroxypropyl-terminated poly(dimethylsiloxane) (HP-PDMS) or hydroxyethoxypropyl-terminated poly(dimethylsiloxane) (EO-PDMS) as soft segments, and 4,4'-methylenediphenyl diisocyanate and 1,4-butanediol as hard segments were investigated. The polyurethanes were synthesized by two-step polyaddition in solution. The effects of the type and content of PDMS segments on the structure, thermal and surface properties of copolymers were studied by H-1-, C-13-nuclear magnetic resonance (NMR) spectroscopy and two-dimensional NMR spectroscopies (heteronuclear multiple bond correlation (HMBC) and rotating-frame nuclear Overhauser effect (ROESY)), gel permeation chromatography (GPC), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), wide-angle X-ray scattering (WAXS), scanning electron microscopy (SEM) and water contact angle and water absorption measurements. Thermal properties investigated by DSC indicated that the presence of soft PDMS segments lowers the glass transition and melting temperatures of the hard phase as well as the degree of crystallinity. SEM analysis of the copolymers with a lower soft segment content confirmed the presence of spherulite superstructures, which arise from the crystallization of the hard segments. When compared with polyurethanes prepared from HP-PDMS, the copolymers synthesized from EO-PDMS with the same content of the soft segments had a higher degree of crystallinity, better thermal stability and a less hydrophobic surface. The obtained results showed that the synthesized polyurethanes had good thermal and surface properties, which could be further modified by changing the type or content of the soft segments.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane)",
volume = "79",
number = "7",
pages = "843",
doi = "10.2298/JSC130819149P"
}

Pergal, M., Stefanović, I., Gođevac, D., Antić, V., Milačić, V., Ostojić, S., Rogan, J. R.,& Đonlagić, J.. (2014). Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane). in Journal of the Serbian Chemical Society
Serbian Chemical Society., 79(7), 843.
https://doi.org/10.2298/JSC130819149P

Pergal M, Stefanović I, Gođevac D, Antić V, Milačić V, Ostojić S, Rogan JR, Đonlagić J. Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane). in Journal of the Serbian Chemical Society. 2014;79(7):843.
doi:10.2298/JSC130819149P .

Pergal, Marija, Stefanović, Ivan, Gođevac, Dejan, Antić, Vesna, Milačić, Vesna, Ostojić, Sanja, Rogan, Jelena R., Đonlagić, Jasna, "Structural, thermal and surface characterization of thermoplastic polyurethanes based on poly(dimethylsiloxane)" in Journal of the Serbian Chemical Society, 79, no. 7 (2014):843,
https://doi.org/10.2298/JSC130819149P . .

TY  - JOUR
AU  - Balaban, Milica
AU  - Antić, Vesna
AU  - Pergal, Marija
AU  - Gođevac, Dejan
AU  - Francolini, Iolanda
AU  - Martinelli, Andrea
AU  - Rogan, Jelena R.
AU  - Đonlagić, Jasna
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1204
AB  - Segmented poly(urethane-urea-siloxane)s (PUUS) were synthesized using 4,4'-methylenediphenyl diisocyanate (MDI) and ethylene diamine (ED) as the hard segment components and hydroxypropyl-terminated poly(dimethylsiloxane) (PDMS) as the soft segment component, where the hard segment content ranged from 38 to 65 wt%. Segmented PUUSs were prepared by a two-step polymerization procedure in tetrahydrofuran/N-methylpyrrolidone (THF/NMP) mixture with a large proportion of polar solvent. The structure, composition and hard segment length were determined by C-13 NMR and two-dimensional correlation spectroscopy. Thermal, mechanical, small-angle X-ray scattering and hydrogen bonding analyses indicated the formation of the microphase-separated copolymers with high tensile strength. Globular superstructures observed in the copolymer films by scanning electron microscopy (SEM) and atomic force microscopy (AFM) were probably arisen from the microstructural organization of the MDI-ED segments, depending on their content and length. The PUUS copolymers showed high water resistance and became more hydrophobic with increasing weight fraction of PDMS.
PB  - Springer Verlag
T2  - Polymer Bulletin
T1  - Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties
VL  - 70
IS  - 9
SP  - 2493
EP  - 2518
DO  - 10.1007/s00289-013-0968-2
ER  - 

@article{
author = "Balaban, Milica and Antić, Vesna and Pergal, Marija and Gođevac, Dejan and Francolini, Iolanda and Martinelli, Andrea and Rogan, Jelena R. and Đonlagić, Jasna",
year = "2013",
abstract = "Segmented poly(urethane-urea-siloxane)s (PUUS) were synthesized using 4,4'-methylenediphenyl diisocyanate (MDI) and ethylene diamine (ED) as the hard segment components and hydroxypropyl-terminated poly(dimethylsiloxane) (PDMS) as the soft segment component, where the hard segment content ranged from 38 to 65 wt%. Segmented PUUSs were prepared by a two-step polymerization procedure in tetrahydrofuran/N-methylpyrrolidone (THF/NMP) mixture with a large proportion of polar solvent. The structure, composition and hard segment length were determined by C-13 NMR and two-dimensional correlation spectroscopy. Thermal, mechanical, small-angle X-ray scattering and hydrogen bonding analyses indicated the formation of the microphase-separated copolymers with high tensile strength. Globular superstructures observed in the copolymer films by scanning electron microscopy (SEM) and atomic force microscopy (AFM) were probably arisen from the microstructural organization of the MDI-ED segments, depending on their content and length. The PUUS copolymers showed high water resistance and became more hydrophobic with increasing weight fraction of PDMS.",
publisher = "Springer Verlag",
journal = "Polymer Bulletin",
title = "Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties",
volume = "70",
number = "9",
pages = "2493-2518",
doi = "10.1007/s00289-013-0968-2"
}

Balaban, M., Antić, V., Pergal, M., Gođevac, D., Francolini, I., Martinelli, A., Rogan, J. R.,& Đonlagić, J.. (2013). Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties. in Polymer Bulletin
Springer Verlag., 70(9), 2493-2518.
https://doi.org/10.1007/s00289-013-0968-2

Balaban M, Antić V, Pergal M, Gođevac D, Francolini I, Martinelli A, Rogan JR, Đonlagić J. Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties. in Polymer Bulletin. 2013;70(9):2493-2518.
doi:10.1007/s00289-013-0968-2 .

Balaban, Milica, Antić, Vesna, Pergal, Marija, Gođevac, Dejan, Francolini, Iolanda, Martinelli, Andrea, Rogan, Jelena R., Đonlagić, Jasna, "Influence of the chemical structure of poly(urea-urethane-siloxane)s on their morphological, surface and thermal properties" in Polymer Bulletin, 70, no. 9 (2013):2493-2518,
https://doi.org/10.1007/s00289-013-0968-2 . .

TY  - CONF
AU  - Stefanović, Ivan
AU  - Pergal, Marija
AU  - Vasiljević-Radović, Dana
AU  - Gođevac, Dejan
AU  - Antić, Vesna
AU  - Đonlagić, Jasna
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6488
AB  - Polyurethane copolymers based on poly(dimethylsiloxane) represent an important class of thermoplastic elastomers, whirls due to good mechanical and surface properties as well as biocompatibility, may be of interest as biomaterials. In this work, the surface properties of a series of new thermoplastic polyurethanes (TPUs), based on 4,4'-methylenediphenyl diisocyanate and 1,4-butanediol as the hard segments and α,ω-dihydroxypropyl-poly(dimethylsiloxane) (PDMS) as the soft segments, were investigated. The molecular structure and composition of the copolymers were determined by 2D NMR and quantitative 13C NMR spectroscopy. Surface properties of the copolymers were investigated by water contact angle measurements, water absorption and atomic force microscopy (AFM). AFM analysis revealed existence of spherulitic morphology of the copolymers. Also, the results of AFM analysis showed that the coefficient of roughness of TPUs increased with increasing the hard segment content. The hydrophobicity of copolymers increased with increasing the weight fraction of PDMS. This behavior may be ascribed to a tendency of the PDMS segments to migrate on the surface of TPUs caused by its low surface energy.
AB  - Poliuretanski kopolimeri na bazi poli(dimetilsiloksana) predstavljaju važnu klasu termoplastičnih elastomera koji zbog izuzetnih mehaničkih i površinskih svojstava, kao i biokompatibilnosti, mogu biti interesantni kao biomaterijali. U ovom radu su ispitana površinska svojstva serije novih termoplastičnih poliuretana (TPUs) sa tvrdim segmentima na bazi 4,4'-metilendifenildiizocijanata i 1,4-butandiola i mekim segmentima na bazi α,ω-dihidroksipropil-poli(dimetilsiloksana) (PDMS). Struktura i sastav TPU su određeni 2D NMR i kvantitativnom 13C NMR spektroskopijom. Površinska svojstva TPU su ispitana određivanjem kontaktnih uglova i merenjem apsorpcije vode, kao i atomskom mikroskopijom sila (AFM). Na osnovu AFM analize uočeno je da kopolimeri pokazuju sferulitnu morfologiju. Takode, rezultati AFM analize su pokazali da se sa povećanjem sadržaja tvrdih segmenata povećavao koeficijent hrapavosti TPU. Hidrofobnost kopolimera je rasla sa povećanjem sadržaja PDMS-a. Ovo ponašanje se može pripisati tendenciji PDMS da migrira na površinu TPU, zbog male površinske energije PDMS-a.
PB  - Belgrade : Serbian Chemical Society
C3  - Program i kratki izvodi radova - 50. jubilarno savetovanje Srpskog hemijskog društva, 14-15.06.2012, Beograd / Program and Book of abstracts - 50th Golden Jubilee Meeting of the Serbian Chemical Society, 14-15. June 2012, Belgrade
T1  - Surface properties of polyurethane copolymers based on α,ω-dihydroxypropyl-poly(dimethylsiloxane)
T1  - Površinska svojstva poliuretanskih kopolimera na bazi α,ω-dihidroksipropil-poli(deimetilsiloksana)
SP  - 140
EP  - 140
UR  - https://hdl.handle.net/21.15107/rcub_cer_6488
ER  - 

@conference{
author = "Stefanović, Ivan and Pergal, Marija and Vasiljević-Radović, Dana and Gođevac, Dejan and Antić, Vesna and Đonlagić, Jasna",
year = "2012",
abstract = "Polyurethane copolymers based on poly(dimethylsiloxane) represent an important class of thermoplastic elastomers, whirls due to good mechanical and surface properties as well as biocompatibility, may be of interest as biomaterials. In this work, the surface properties of a series of new thermoplastic polyurethanes (TPUs), based on 4,4'-methylenediphenyl diisocyanate and 1,4-butanediol as the hard segments and α,ω-dihydroxypropyl-poly(dimethylsiloxane) (PDMS) as the soft segments, were investigated. The molecular structure and composition of the copolymers were determined by 2D NMR and quantitative 13C NMR spectroscopy. Surface properties of the copolymers were investigated by water contact angle measurements, water absorption and atomic force microscopy (AFM). AFM analysis revealed existence of spherulitic morphology of the copolymers. Also, the results of AFM analysis showed that the coefficient of roughness of TPUs increased with increasing the hard segment content. The hydrophobicity of copolymers increased with increasing the weight fraction of PDMS. This behavior may be ascribed to a tendency of the PDMS segments to migrate on the surface of TPUs caused by its low surface energy., Poliuretanski kopolimeri na bazi poli(dimetilsiloksana) predstavljaju važnu klasu termoplastičnih elastomera koji zbog izuzetnih mehaničkih i površinskih svojstava, kao i biokompatibilnosti, mogu biti interesantni kao biomaterijali. U ovom radu su ispitana površinska svojstva serije novih termoplastičnih poliuretana (TPUs) sa tvrdim segmentima na bazi 4,4'-metilendifenildiizocijanata i 1,4-butandiola i mekim segmentima na bazi α,ω-dihidroksipropil-poli(dimetilsiloksana) (PDMS). Struktura i sastav TPU su određeni 2D NMR i kvantitativnom 13C NMR spektroskopijom. Površinska svojstva TPU su ispitana određivanjem kontaktnih uglova i merenjem apsorpcije vode, kao i atomskom mikroskopijom sila (AFM). Na osnovu AFM analize uočeno je da kopolimeri pokazuju sferulitnu morfologiju. Takode, rezultati AFM analize su pokazali da se sa povećanjem sadržaja tvrdih segmenata povećavao koeficijent hrapavosti TPU. Hidrofobnost kopolimera je rasla sa povećanjem sadržaja PDMS-a. Ovo ponašanje se može pripisati tendenciji PDMS da migrira na površinu TPU, zbog male površinske energije PDMS-a.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Program i kratki izvodi radova - 50. jubilarno savetovanje Srpskog hemijskog društva, 14-15.06.2012, Beograd / Program and Book of abstracts - 50th Golden Jubilee Meeting of the Serbian Chemical Society, 14-15. June 2012, Belgrade",
title = "Surface properties of polyurethane copolymers based on α,ω-dihydroxypropyl-poly(dimethylsiloxane), Površinska svojstva poliuretanskih kopolimera na bazi α,ω-dihidroksipropil-poli(deimetilsiloksana)",
pages = "140-140",
url = "https://hdl.handle.net/21.15107/rcub_cer_6488"
}

Stefanović, I., Pergal, M., Vasiljević-Radović, D., Gođevac, D., Antić, V.,& Đonlagić, J.. (2012). Surface properties of polyurethane copolymers based on α,ω-dihydroxypropyl-poly(dimethylsiloxane). in Program i kratki izvodi radova - 50. jubilarno savetovanje Srpskog hemijskog društva, 14-15.06.2012, Beograd / Program and Book of abstracts - 50th Golden Jubilee Meeting of the Serbian Chemical Society, 14-15. June 2012, Belgrade
Belgrade : Serbian Chemical Society., 140-140.
https://hdl.handle.net/21.15107/rcub_cer_6488

Stefanović I, Pergal M, Vasiljević-Radović D, Gođevac D, Antić V, Đonlagić J. Surface properties of polyurethane copolymers based on α,ω-dihydroxypropyl-poly(dimethylsiloxane). in Program i kratki izvodi radova - 50. jubilarno savetovanje Srpskog hemijskog društva, 14-15.06.2012, Beograd / Program and Book of abstracts - 50th Golden Jubilee Meeting of the Serbian Chemical Society, 14-15. June 2012, Belgrade. 2012;:140-140.
https://hdl.handle.net/21.15107/rcub_cer_6488 .

Stefanović, Ivan, Pergal, Marija, Vasiljević-Radović, Dana, Gođevac, Dejan, Antić, Vesna, Đonlagić, Jasna, "Surface properties of polyurethane copolymers based on α,ω-dihydroxypropyl-poly(dimethylsiloxane)" in Program i kratki izvodi radova - 50. jubilarno savetovanje Srpskog hemijskog društva, 14-15.06.2012, Beograd / Program and Book of abstracts - 50th Golden Jubilee Meeting of the Serbian Chemical Society, 14-15. June 2012, Belgrade (2012):140-140,
https://hdl.handle.net/21.15107/rcub_cer_6488 .

TY  - JOUR
AU  - Pergal, Marija
AU  - Antić, Vesna
AU  - Tovilović, Gordana
AU  - Nestorov, Jelena
AU  - Vasiljević-Radović, Dana
AU  - Đonlagić, Jasna
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1110
AB  - Novel polyurethane co-polymers (TPUs), based on poly(epsilon-caprolactone)-block-poly(dimethylsiloxane)-block-poly(epsilon-caprolactone) (PCL-PDMS-PCL) as soft segment and 4,4'-methylenediphenyl diisocyanate (MDI) and 1,4-butanediol (BD) as hard segment, were synthesized and evaluated for biomedical applications. The content of hard segments (HS) in the polymer chains was varied from 9 to 63 wt%. The influence of the content and length of the HS on the thermal, surface, mechanical properties and biocompatibility was investigated. The structure, composition and HS length were examined using H-1- and quantitative C-13-NMR spectroscopy. DSC results implied that the synthesized TPUs were semicrystalline polymers in which both the hard MDI/BD and soft PCL-PDMS-PCL segments participated. It was found that an increase in the average HS length (from 1.2 to 14.4 MDI/BD units) was accompanied by an increase in the crystallinity of the hard segments, storage moduli, hydrophilicity and degree of microphase separation of the co-polymers. Depending on the HS content, a gradual variation in surface properties of co-polymers was revealed by FTIR, AFM and static water contact angle measurements. The in vitro biocompatibility of co-polymers was evaluated using the endothelial EA. hy926 cell line and protein adsorption on the polyurethane films. All synthesized TPUs adsorbed more albumin than fibrinogen from multicomponent protein mixture, which may indicate biocompatibility. The polyurethane films with high HS content and/or high roughness coefficient exhibit good surface properties and biocompatible behavior, which was confirmed by non-toxic effects to cells and good cell adhesion. Therefore, the non-cytotoxic chemistry of the co-polymers makes them good candidates for further development as biomedical implants.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Journal of Biomaterials Science-Polymer Edition
T1  - In Vitro Biocompatibility Evaluation of Novel Urethane-Siloxane Co-Polymers Based on Poly(epsilon-Caprolactone)-block-Poly(Dimethylsiloxane)-block-Poly(epsilon-Caprolactone)
VL  - 23
IS  - 13
SP  - 1629
EP  - 1657
DO  - 10.1163/092050611X589338
ER  - 

@article{
author = "Pergal, Marija and Antić, Vesna and Tovilović, Gordana and Nestorov, Jelena and Vasiljević-Radović, Dana and Đonlagić, Jasna",
year = "2012",
abstract = "Novel polyurethane co-polymers (TPUs), based on poly(epsilon-caprolactone)-block-poly(dimethylsiloxane)-block-poly(epsilon-caprolactone) (PCL-PDMS-PCL) as soft segment and 4,4'-methylenediphenyl diisocyanate (MDI) and 1,4-butanediol (BD) as hard segment, were synthesized and evaluated for biomedical applications. The content of hard segments (HS) in the polymer chains was varied from 9 to 63 wt%. The influence of the content and length of the HS on the thermal, surface, mechanical properties and biocompatibility was investigated. The structure, composition and HS length were examined using H-1- and quantitative C-13-NMR spectroscopy. DSC results implied that the synthesized TPUs were semicrystalline polymers in which both the hard MDI/BD and soft PCL-PDMS-PCL segments participated. It was found that an increase in the average HS length (from 1.2 to 14.4 MDI/BD units) was accompanied by an increase in the crystallinity of the hard segments, storage moduli, hydrophilicity and degree of microphase separation of the co-polymers. Depending on the HS content, a gradual variation in surface properties of co-polymers was revealed by FTIR, AFM and static water contact angle measurements. The in vitro biocompatibility of co-polymers was evaluated using the endothelial EA. hy926 cell line and protein adsorption on the polyurethane films. All synthesized TPUs adsorbed more albumin than fibrinogen from multicomponent protein mixture, which may indicate biocompatibility. The polyurethane films with high HS content and/or high roughness coefficient exhibit good surface properties and biocompatible behavior, which was confirmed by non-toxic effects to cells and good cell adhesion. Therefore, the non-cytotoxic chemistry of the co-polymers makes them good candidates for further development as biomedical implants.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Journal of Biomaterials Science-Polymer Edition",
title = "In Vitro Biocompatibility Evaluation of Novel Urethane-Siloxane Co-Polymers Based on Poly(epsilon-Caprolactone)-block-Poly(Dimethylsiloxane)-block-Poly(epsilon-Caprolactone)",
volume = "23",
number = "13",
pages = "1629-1657",
doi = "10.1163/092050611X589338"
}

Pergal, M., Antić, V., Tovilović, G., Nestorov, J., Vasiljević-Radović, D.,& Đonlagić, J.. (2012). In Vitro Biocompatibility Evaluation of Novel Urethane-Siloxane Co-Polymers Based on Poly(epsilon-Caprolactone)-block-Poly(Dimethylsiloxane)-block-Poly(epsilon-Caprolactone). in Journal of Biomaterials Science-Polymer Edition
Taylor & Francis Ltd, Abingdon., 23(13), 1629-1657.
https://doi.org/10.1163/092050611X589338

Pergal M, Antić V, Tovilović G, Nestorov J, Vasiljević-Radović D, Đonlagić J. In Vitro Biocompatibility Evaluation of Novel Urethane-Siloxane Co-Polymers Based on Poly(epsilon-Caprolactone)-block-Poly(Dimethylsiloxane)-block-Poly(epsilon-Caprolactone). in Journal of Biomaterials Science-Polymer Edition. 2012;23(13):1629-1657.
doi:10.1163/092050611X589338 .

Pergal, Marija, Antić, Vesna, Tovilović, Gordana, Nestorov, Jelena, Vasiljević-Radović, Dana, Đonlagić, Jasna, "In Vitro Biocompatibility Evaluation of Novel Urethane-Siloxane Co-Polymers Based on Poly(epsilon-Caprolactone)-block-Poly(Dimethylsiloxane)-block-Poly(epsilon-Caprolactone)" in Journal of Biomaterials Science-Polymer Edition, 23, no. 13 (2012):1629-1657,
https://doi.org/10.1163/092050611X589338 . .

TY  - JOUR
AU  - Balaban, Milica
AU  - Antić, Vesna
AU  - Pergal, Marija
AU  - Francolini, Iolanda
AU  - Martinelli, Andrea
AU  - Đonlagić, Jasna
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1123
AB  - Segmented poly(urethane-urea-siloxanes) (PUUS) based on 4,4'- methylene diphenyl diisocyanate-ethylene diamine (MDI-ED) hard segments and hydroxypropyl-terminated poly(dimethylsiloxane) (PDMS, Mn = 1000 g mol-1) soft segments were prepared under various experimental conditions. The copolymers with constant molar ratio of hard and soft segments (PDMS:MDI:ED = 1:2:1; 20 wt. % of the hard segments) were synthesized in two different solvent mixtures, by a two-step polyaddition procedure. The first one was tetrahydrofuran/N,N-dimethylacetamide (THF/DMAc) with different co-solvent ratios (1/1, 1/2 and 1/9, v/v), whereas the second one was tetrahydrofuran/N-methylpyrrolidone (THF/NMP, 1/9, v/v). The reaction conditions were optimized by varying the co-solvents ratio, the concentration of the catalyst, the initial monomer concentration, as well as the time of the first and the second step of the reaction. The effects of the experimental conditions on the size of the PUUS were investigated by gel permeation chromatography (GPC) and dilute solution viscometry. The copolymers with the highest molecular weights were obtained in the THF/NMP mixture (1/9, v/v). The structure and composition of the copolymers were determined by 1H-NMR and FTIR spectroscopy. The morphology of the synthesized copolymers was investigated by atomic force microscopy (AFM), while the thermal properties were studied by differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The surface properties were evaluated by measuring the water contact angle (WCA). The copolymers exhibited phase-separated microstructure and were stable up to 200°C in nitrogen.
AB  - Segmentirani poli(uretan-urea-siloksani) (PUUS), sa tvrdim segmentima na bazi 4,4'-metilendifenildiizocijanata i etilendiamina (MDI-ED) i mekim segmentima na bazi hidroksipropil-terminiranog poli(dimetilsiloksana) (PDMS, Mn = 1000 g mol-1), sintetisani su pod različitim eksperimentalnim uslovima. Kopolimeri sa konstantnim molskim odnosom tvrdih i mekih segmenata (PDMS:MDI:ED = 1:2:1; 20 mas. % tvrdih segmenata), sintetisani su u dve različite smeše rastvarača kao reakcionog medijuma, metodom dvostepene poliadicije. Prva kombinacija rastvarača je bila smeša tetrahidrofurana (THF) i N,N-dimetilacetamida (DMAc), dok je u drugom slučaju korišćena smeša THF-a i N-metilpirolidona (NMP). Reakcioni uslovi su optimizovani u pogledu odnosa ko-rastvarača, koncentracije katalizatora, početne koncentracije monomera i vremena odigravanja prve i druge faze reakcije. Ispitan je uticaj primenjenih eksperimentalnih uslova na veličinu PUUS primenom gel-propusne hromatografije (GPC) i viskozimetrije razblaženih rastvora [η]. Kopolimeri najvećih molarnih masa su dobijeni u smeši THF/NMP (1/9, v/v). Struktura i sastav kopolimera su okarakterisani 1H-NMR i FTIR spektroskopijom. Morfologija sintetisanih kopolimera je ispitana mikroskopijom atomskih sila (AFM), dok su termička svojstva ispitana diferencijalnom skenirajućom kalorimetrijom (DSC) i termogravimetrijskom analizom (TGA). Površinska svojstva kopolimera su ispitana određivanjem kontaktnih uglova sa vodom (WCA). Kopolimeri su pokazali dvofaznu mikrostrukturu i bili su stabilni do 200°C u atmosteri azota.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - The effect of polar solvents on the synthesis of poly(urethane-urea-siloxane)s
T1  - Uticaj polarnih rastvarača na sintezu poli(uretan-urea-siloksana)
VL  - 77
IS  - 10
SP  - 1457
EP  - 1481
DO  - 10.2298/JSC111025056B
ER  - 

@article{
author = "Balaban, Milica and Antić, Vesna and Pergal, Marija and Francolini, Iolanda and Martinelli, Andrea and Đonlagić, Jasna",
year = "2012",
abstract = "Segmented poly(urethane-urea-siloxanes) (PUUS) based on 4,4'- methylene diphenyl diisocyanate-ethylene diamine (MDI-ED) hard segments and hydroxypropyl-terminated poly(dimethylsiloxane) (PDMS, Mn = 1000 g mol-1) soft segments were prepared under various experimental conditions. The copolymers with constant molar ratio of hard and soft segments (PDMS:MDI:ED = 1:2:1; 20 wt. % of the hard segments) were synthesized in two different solvent mixtures, by a two-step polyaddition procedure. The first one was tetrahydrofuran/N,N-dimethylacetamide (THF/DMAc) with different co-solvent ratios (1/1, 1/2 and 1/9, v/v), whereas the second one was tetrahydrofuran/N-methylpyrrolidone (THF/NMP, 1/9, v/v). The reaction conditions were optimized by varying the co-solvents ratio, the concentration of the catalyst, the initial monomer concentration, as well as the time of the first and the second step of the reaction. The effects of the experimental conditions on the size of the PUUS were investigated by gel permeation chromatography (GPC) and dilute solution viscometry. The copolymers with the highest molecular weights were obtained in the THF/NMP mixture (1/9, v/v). The structure and composition of the copolymers were determined by 1H-NMR and FTIR spectroscopy. The morphology of the synthesized copolymers was investigated by atomic force microscopy (AFM), while the thermal properties were studied by differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The surface properties were evaluated by measuring the water contact angle (WCA). The copolymers exhibited phase-separated microstructure and were stable up to 200°C in nitrogen., Segmentirani poli(uretan-urea-siloksani) (PUUS), sa tvrdim segmentima na bazi 4,4'-metilendifenildiizocijanata i etilendiamina (MDI-ED) i mekim segmentima na bazi hidroksipropil-terminiranog poli(dimetilsiloksana) (PDMS, Mn = 1000 g mol-1), sintetisani su pod različitim eksperimentalnim uslovima. Kopolimeri sa konstantnim molskim odnosom tvrdih i mekih segmenata (PDMS:MDI:ED = 1:2:1; 20 mas. % tvrdih segmenata), sintetisani su u dve različite smeše rastvarača kao reakcionog medijuma, metodom dvostepene poliadicije. Prva kombinacija rastvarača je bila smeša tetrahidrofurana (THF) i N,N-dimetilacetamida (DMAc), dok je u drugom slučaju korišćena smeša THF-a i N-metilpirolidona (NMP). Reakcioni uslovi su optimizovani u pogledu odnosa ko-rastvarača, koncentracije katalizatora, početne koncentracije monomera i vremena odigravanja prve i druge faze reakcije. Ispitan je uticaj primenjenih eksperimentalnih uslova na veličinu PUUS primenom gel-propusne hromatografije (GPC) i viskozimetrije razblaženih rastvora [η]. Kopolimeri najvećih molarnih masa su dobijeni u smeši THF/NMP (1/9, v/v). Struktura i sastav kopolimera su okarakterisani 1H-NMR i FTIR spektroskopijom. Morfologija sintetisanih kopolimera je ispitana mikroskopijom atomskih sila (AFM), dok su termička svojstva ispitana diferencijalnom skenirajućom kalorimetrijom (DSC) i termogravimetrijskom analizom (TGA). Površinska svojstva kopolimera su ispitana određivanjem kontaktnih uglova sa vodom (WCA). Kopolimeri su pokazali dvofaznu mikrostrukturu i bili su stabilni do 200°C u atmosteri azota.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "The effect of polar solvents on the synthesis of poly(urethane-urea-siloxane)s, Uticaj polarnih rastvarača na sintezu poli(uretan-urea-siloksana)",
volume = "77",
number = "10",
pages = "1457-1481",
doi = "10.2298/JSC111025056B"
}

Balaban, M., Antić, V., Pergal, M., Francolini, I., Martinelli, A.,& Đonlagić, J.. (2012). The effect of polar solvents on the synthesis of poly(urethane-urea-siloxane)s. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 77(10), 1457-1481.
https://doi.org/10.2298/JSC111025056B

Balaban M, Antić V, Pergal M, Francolini I, Martinelli A, Đonlagić J. The effect of polar solvents on the synthesis of poly(urethane-urea-siloxane)s. in Journal of the Serbian Chemical Society. 2012;77(10):1457-1481.
doi:10.2298/JSC111025056B .

Balaban, Milica, Antić, Vesna, Pergal, Marija, Francolini, Iolanda, Martinelli, Andrea, Đonlagić, Jasna, "The effect of polar solvents on the synthesis of poly(urethane-urea-siloxane)s" in Journal of the Serbian Chemical Society, 77, no. 10 (2012):1457-1481,
https://doi.org/10.2298/JSC111025056B . .

TY  - CONF
AU  - Pergal, Marija
AU  - Stefanović, Ivan
AU  - Antić, Vesna
AU  - Đonlagić, Jasna
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6487
AB  - Segmented polyurethanes are an important class of thermoplastic elastomers that are used in medicine as long-term implants. Biostability and biocompatibility of polyurethanes can be improved by the introduction of poly(dimethylsiloxane) in the polymer chain. A series of novel thermoplastic polyurethanes (TPUs) was synthesized by two-step polyaddition reaction in solution from 4,4'-methylenediphenyl diisocyanate (MDI), 1,4-butanediol (BD) and alpha-omega-dihydroxypropyl-poly(dimethylsiloxane) (PDMS). The content of soft PDMS segment was varied between 34 and 62 wt.%. The structure and composition of the TPUs were determined by 1H and 13C NMR spectroscopy, while the hydrogen bonding interaction in the TPUs were analyzed by FTIR spectroscopy. The influence of PDMS content on the structure, thermal and some physical properties of the TPUs were also investigated. Thermal stability of the copolymers increased with increasing PDMS content. It was clearly demonstrated that the degree of crystallinity, the melting and crystallization temperatures as well as glass transition temperatures increased with increasing weight fraction of the hard MDI-BD segment. SEM analysis confirmed the presence of a fibrillar morphology, which arises from the crystallization of the MDI-BD segments.
AB  - Segmentirani poliuretani predstavljaju važnu klasu termoplastičnih elastomera koji su našli primenu u medicini za izradu dugotrajnih implanata. Jedan od načina da se poboljša biostabilnost i biokompatibilnost termoplastičnih poliuretana je uvodenje poli(dimetilsiloksana) u polimemi lanac. Serija novih termoplastičnih poliuretana (TPUs) sintetisana je dvostepenom poliadicijom u rastvoru polazeći od 4,4'-metilendifenildiizocijanata (MDI), 1,4-butandiola (BD) i alpha-omega-dihidroksipropil-poli(dimetilsiloksana) (PDMS). Sadržaj mekih PDMS segmenata je variran od 34 do 62 mas%. Struktura i sastav kopolimera odredeni su 1H i 13C NMR spektroskopijom, dok su vrste vodoničnih interakcija u TPUs analizirane FTIR spektroskopijom. Uticaj sadržaja mekog PDMS segmenta na strukturu, termička i neka fizička svojstava kopolimera, su takode ispitani. Termička stabilnost kopolimera se povećavala sa povećanjem sadržaja PDMS-a. Pokazano je da stepen kristaliničnosti, a samim tim i temperature topljenja i kristalizacije, kao i temperatura ostalcliivanja TPUs rastu sa povećanjem masenog udela tvrdih MDI-BD segmanata. SEM analiza je pokazala da sintetisani kopolimeri imaju fibrilarnu morfologiju, koja potiče od kristalizacije MDI-BD segmenata.
PB  - Belgrade : Serbian Chemical Society
C3  - Program i kratki izvodi radova -  XLIX Savetovanje Srpskog hemijskog društva, 13-14. maj 2011., Kragujevac / Programme and book of abstracts - 49th Meeting of the Serbian Chemical Society, 13-14. May 2011. Kragujevac
T1  - The influence of poly(dimethylsiloxane) content on some physical properties of thermoplastic polyurethanes
T1  - Uticaj sadržaja poli(dimetiloksana) na neka fizička svojstva termoplastičnih poliuretana
SP  - 116
EP  - 116
UR  - https://hdl.handle.net/21.15107/rcub_cer_6487
ER  - 

@conference{
author = "Pergal, Marija and Stefanović, Ivan and Antić, Vesna and Đonlagić, Jasna",
year = "2011",
abstract = "Segmented polyurethanes are an important class of thermoplastic elastomers that are used in medicine as long-term implants. Biostability and biocompatibility of polyurethanes can be improved by the introduction of poly(dimethylsiloxane) in the polymer chain. A series of novel thermoplastic polyurethanes (TPUs) was synthesized by two-step polyaddition reaction in solution from 4,4'-methylenediphenyl diisocyanate (MDI), 1,4-butanediol (BD) and alpha-omega-dihydroxypropyl-poly(dimethylsiloxane) (PDMS). The content of soft PDMS segment was varied between 34 and 62 wt.%. The structure and composition of the TPUs were determined by 1H and 13C NMR spectroscopy, while the hydrogen bonding interaction in the TPUs were analyzed by FTIR spectroscopy. The influence of PDMS content on the structure, thermal and some physical properties of the TPUs were also investigated. Thermal stability of the copolymers increased with increasing PDMS content. It was clearly demonstrated that the degree of crystallinity, the melting and crystallization temperatures as well as glass transition temperatures increased with increasing weight fraction of the hard MDI-BD segment. SEM analysis confirmed the presence of a fibrillar morphology, which arises from the crystallization of the MDI-BD segments., Segmentirani poliuretani predstavljaju važnu klasu termoplastičnih elastomera koji su našli primenu u medicini za izradu dugotrajnih implanata. Jedan od načina da se poboljša biostabilnost i biokompatibilnost termoplastičnih poliuretana je uvodenje poli(dimetilsiloksana) u polimemi lanac. Serija novih termoplastičnih poliuretana (TPUs) sintetisana je dvostepenom poliadicijom u rastvoru polazeći od 4,4'-metilendifenildiizocijanata (MDI), 1,4-butandiola (BD) i alpha-omega-dihidroksipropil-poli(dimetilsiloksana) (PDMS). Sadržaj mekih PDMS segmenata je variran od 34 do 62 mas%. Struktura i sastav kopolimera odredeni su 1H i 13C NMR spektroskopijom, dok su vrste vodoničnih interakcija u TPUs analizirane FTIR spektroskopijom. Uticaj sadržaja mekog PDMS segmenta na strukturu, termička i neka fizička svojstava kopolimera, su takode ispitani. Termička stabilnost kopolimera se povećavala sa povećanjem sadržaja PDMS-a. Pokazano je da stepen kristaliničnosti, a samim tim i temperature topljenja i kristalizacije, kao i temperatura ostalcliivanja TPUs rastu sa povećanjem masenog udela tvrdih MDI-BD segmanata. SEM analiza je pokazala da sintetisani kopolimeri imaju fibrilarnu morfologiju, koja potiče od kristalizacije MDI-BD segmenata.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Program i kratki izvodi radova -  XLIX Savetovanje Srpskog hemijskog društva, 13-14. maj 2011., Kragujevac / Programme and book of abstracts - 49th Meeting of the Serbian Chemical Society, 13-14. May 2011. Kragujevac",
title = "The influence of poly(dimethylsiloxane) content on some physical properties of thermoplastic polyurethanes, Uticaj sadržaja poli(dimetiloksana) na neka fizička svojstva termoplastičnih poliuretana",
pages = "116-116",
url = "https://hdl.handle.net/21.15107/rcub_cer_6487"
}

Pergal, M., Stefanović, I., Antić, V.,& Đonlagić, J.. (2011). The influence of poly(dimethylsiloxane) content on some physical properties of thermoplastic polyurethanes. in Program i kratki izvodi radova -  XLIX Savetovanje Srpskog hemijskog društva, 13-14. maj 2011., Kragujevac / Programme and book of abstracts - 49th Meeting of the Serbian Chemical Society, 13-14. May 2011. Kragujevac
Belgrade : Serbian Chemical Society., 116-116.
https://hdl.handle.net/21.15107/rcub_cer_6487

Pergal M, Stefanović I, Antić V, Đonlagić J. The influence of poly(dimethylsiloxane) content on some physical properties of thermoplastic polyurethanes. in Program i kratki izvodi radova -  XLIX Savetovanje Srpskog hemijskog društva, 13-14. maj 2011., Kragujevac / Programme and book of abstracts - 49th Meeting of the Serbian Chemical Society, 13-14. May 2011. Kragujevac. 2011;:116-116.
https://hdl.handle.net/21.15107/rcub_cer_6487 .

Pergal, Marija, Stefanović, Ivan, Antić, Vesna, Đonlagić, Jasna, "The influence of poly(dimethylsiloxane) content on some physical properties of thermoplastic polyurethanes" in Program i kratki izvodi radova -  XLIX Savetovanje Srpskog hemijskog društva, 13-14. maj 2011., Kragujevac / Programme and book of abstracts - 49th Meeting of the Serbian Chemical Society, 13-14. May 2011. Kragujevac (2011):116-116,
https://hdl.handle.net/21.15107/rcub_cer_6487 .

TY  - JOUR
AU  - Pergal, Marija
AU  - Antić, Vesna
AU  - Ostojić, Sanja
AU  - Marinović-Cincović, Milena
AU  - Đonlagić, Jasna
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/804
AB  - A series of novel thermoplastic urethane-siloxane copolymers (TPUSs) based on a α,ω-dihydroxy-[poly(ε-caprolactone)-b-poly(dimethylsiloxane)-b- -poly(ε-caprolactone)] (α,ω-dihydroxy-PCL-PDMS-PCL) triblock copolymer, 4,4'-methylenediphenyl diisocyanate (MDI) and 1,4-butanediol (BD) was synthesized. The effects of the content (9-63 mass %) of hard urethane segments and their degree of polymerization on the properties of the segmented TPUSs were investigated. The structure, composition and hard segment degree of polymerization of the hard segments were examined using 1H- and quantitative 13C-NMR spectroscopy. The degree of crystallinity of the synthesized copolymers was determined using wide-angle X-ray scattering (WAXS). The surface properties were evaluated by measuring the water contact angle and water absorption. In the series of the TPUSs, the average degree of polymerization of the hard segments was varied from 1.2 to 14.4 MDI-BD units. It was found that average values from 3.8 to 14.4 MDI-BD units were effective segment lengths for crystallization of hard segments, which resulted in an increase in the degree of microphase separation of the copolymers. Spherulite-like superstructures were observed in copolymer films by scanning electron microscopy (SEM), which are believed to arise from the crystallization of the hard segments and/or PCL segments, depending on the content of the hard segments. The surface of the copolymers became more hydrophobic with increasing weight fraction of PDMS. The synthesized copolymers based on a PCL-PDMS-PCL segment showed good thermal stability, which increased with increasing content of soft PDMS segments, as was confirmed by the value of the starting temperature of thermal degradation.
AB  - U ovom radu prikazana je struktura i neka svojstva serije novih termoplastičnih uretan-siloksanskih kopolimera (TPUSs) na bazi α,ω-dihidroksi-[poli(ε-kaprolakton)-b-poli(dimetilsiloksan)-b-poli(ε-kaprolakton)] triblok kopolimera (α,ω-dihidroksi-PCL-PDMS-PCL), 4,4'-metilendifenildiizocijanata (MDI) i 1,4-butandiola (BD). Ispitan je uticaj sadržaja uretanskog tvrdog segmenta (9-63 mas. %) i njegove dužine, tj. stepena polimerizacije, izražene preko broja MDI-BD ostataka, na svojstva segmentiranih TPUSs. Struktura, sastav i stepen polimerizacije tvrdog segmenta su ispitani pomoću 1H- i kvantitativne 13C-NMR spektroskopije. Stepen kristaliničnosti kopolimera je određen metodom difrakcije X-zraka na velikim uglovima (WAXS). Površinska svojstva kopolimera su ispitana određivanjem kontaktnih uglova sa vodom i merenjem apsorpcije vode. U seriji kopolimera dužina tvrdog segmenta izražena preko broja ponavljajućih MDI-BD jedinica je varirana od 1,2 do 14,4. Utvrđeno je da tvrdi segmenti sa 3,8 do 14,4 ponavljajućih MDI-BD jedinica efikasno kristališu, što je rezultovalo u povećanju stepena mikrofazne separacije kopolimera. SEM analiza je pokazala prisustvo sferulitne strukture u kopolimernim filmovima, koja najverovatnije potiče od kristalizacije tvrdih i/ili PCL segmenata, zavisno od sadržaja tvrdih segmenata. Hidrofobnost površine kopolimera je rasla sa povećanjem masenog udela PDMS-a u odgovarajućem uzorku. Sintetisani poliuretani na bazi PCL-PDMS-PCL pokazuju povećanje termičke stabilnosti sa povećanjem sadržaja mekih PDMS segmenata, što je potvrđeno porastom početne temperature degradacije, određene TG analizom.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Influence of the content of hard segments on the properties of novel urethane-siloxane copolymers based on a poly(ε-caprolactone)-b-poly(dimethylsiloxane)-b-poly(ε-caprolactone) triblock copolymer
T1  - Uticaj sadržaja tvrdog segmenta na svojstva novih uretan-siloksanskih kopolimera na bazi poli(e-kaprolakton)-b-poli(dimetilsiloksan)-b-poli(e-kaprolaktona)
VL  - 76
IS  - 12
SP  - 1703
EP  - 1723
DO  - 10.2298/JSC110307146P
ER  - 

@article{
author = "Pergal, Marija and Antić, Vesna and Ostojić, Sanja and Marinović-Cincović, Milena and Đonlagić, Jasna",
year = "2011",
abstract = "A series of novel thermoplastic urethane-siloxane copolymers (TPUSs) based on a α,ω-dihydroxy-[poly(ε-caprolactone)-b-poly(dimethylsiloxane)-b- -poly(ε-caprolactone)] (α,ω-dihydroxy-PCL-PDMS-PCL) triblock copolymer, 4,4'-methylenediphenyl diisocyanate (MDI) and 1,4-butanediol (BD) was synthesized. The effects of the content (9-63 mass %) of hard urethane segments and their degree of polymerization on the properties of the segmented TPUSs were investigated. The structure, composition and hard segment degree of polymerization of the hard segments were examined using 1H- and quantitative 13C-NMR spectroscopy. The degree of crystallinity of the synthesized copolymers was determined using wide-angle X-ray scattering (WAXS). The surface properties were evaluated by measuring the water contact angle and water absorption. In the series of the TPUSs, the average degree of polymerization of the hard segments was varied from 1.2 to 14.4 MDI-BD units. It was found that average values from 3.8 to 14.4 MDI-BD units were effective segment lengths for crystallization of hard segments, which resulted in an increase in the degree of microphase separation of the copolymers. Spherulite-like superstructures were observed in copolymer films by scanning electron microscopy (SEM), which are believed to arise from the crystallization of the hard segments and/or PCL segments, depending on the content of the hard segments. The surface of the copolymers became more hydrophobic with increasing weight fraction of PDMS. The synthesized copolymers based on a PCL-PDMS-PCL segment showed good thermal stability, which increased with increasing content of soft PDMS segments, as was confirmed by the value of the starting temperature of thermal degradation., U ovom radu prikazana je struktura i neka svojstva serije novih termoplastičnih uretan-siloksanskih kopolimera (TPUSs) na bazi α,ω-dihidroksi-[poli(ε-kaprolakton)-b-poli(dimetilsiloksan)-b-poli(ε-kaprolakton)] triblok kopolimera (α,ω-dihidroksi-PCL-PDMS-PCL), 4,4'-metilendifenildiizocijanata (MDI) i 1,4-butandiola (BD). Ispitan je uticaj sadržaja uretanskog tvrdog segmenta (9-63 mas. %) i njegove dužine, tj. stepena polimerizacije, izražene preko broja MDI-BD ostataka, na svojstva segmentiranih TPUSs. Struktura, sastav i stepen polimerizacije tvrdog segmenta su ispitani pomoću 1H- i kvantitativne 13C-NMR spektroskopije. Stepen kristaliničnosti kopolimera je određen metodom difrakcije X-zraka na velikim uglovima (WAXS). Površinska svojstva kopolimera su ispitana određivanjem kontaktnih uglova sa vodom i merenjem apsorpcije vode. U seriji kopolimera dužina tvrdog segmenta izražena preko broja ponavljajućih MDI-BD jedinica je varirana od 1,2 do 14,4. Utvrđeno je da tvrdi segmenti sa 3,8 do 14,4 ponavljajućih MDI-BD jedinica efikasno kristališu, što je rezultovalo u povećanju stepena mikrofazne separacije kopolimera. SEM analiza je pokazala prisustvo sferulitne strukture u kopolimernim filmovima, koja najverovatnije potiče od kristalizacije tvrdih i/ili PCL segmenata, zavisno od sadržaja tvrdih segmenata. Hidrofobnost površine kopolimera je rasla sa povećanjem masenog udela PDMS-a u odgovarajućem uzorku. Sintetisani poliuretani na bazi PCL-PDMS-PCL pokazuju povećanje termičke stabilnosti sa povećanjem sadržaja mekih PDMS segmenata, što je potvrđeno porastom početne temperature degradacije, određene TG analizom.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Influence of the content of hard segments on the properties of novel urethane-siloxane copolymers based on a poly(ε-caprolactone)-b-poly(dimethylsiloxane)-b-poly(ε-caprolactone) triblock copolymer, Uticaj sadržaja tvrdog segmenta na svojstva novih uretan-siloksanskih kopolimera na bazi poli(e-kaprolakton)-b-poli(dimetilsiloksan)-b-poli(e-kaprolaktona)",
volume = "76",
number = "12",
pages = "1703-1723",
doi = "10.2298/JSC110307146P"
}

Pergal, M., Antić, V., Ostojić, S., Marinović-Cincović, M.,& Đonlagić, J.. (2011). Influence of the content of hard segments on the properties of novel urethane-siloxane copolymers based on a poly(ε-caprolactone)-b-poly(dimethylsiloxane)-b-poly(ε-caprolactone) triblock copolymer. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 76(12), 1703-1723.
https://doi.org/10.2298/JSC110307146P

Pergal M, Antić V, Ostojić S, Marinović-Cincović M, Đonlagić J. Influence of the content of hard segments on the properties of novel urethane-siloxane copolymers based on a poly(ε-caprolactone)-b-poly(dimethylsiloxane)-b-poly(ε-caprolactone) triblock copolymer. in Journal of the Serbian Chemical Society. 2011;76(12):1703-1723.
doi:10.2298/JSC110307146P .

Pergal, Marija, Antić, Vesna, Ostojić, Sanja, Marinović-Cincović, Milena, Đonlagić, Jasna, "Influence of the content of hard segments on the properties of novel urethane-siloxane copolymers based on a poly(ε-caprolactone)-b-poly(dimethylsiloxane)-b-poly(ε-caprolactone) triblock copolymer" in Journal of the Serbian Chemical Society, 76, no. 12 (2011):1703-1723,
https://doi.org/10.2298/JSC110307146P . .

TY  - JOUR
AU  - Pergal, Marija
AU  - Antić, Vesna
AU  - Govedarica, Milutin
AU  - Gođevac, Dejan
AU  - Ostojić, Sanja
AU  - Đonlagić, Jasna
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/859
AB  - Novel polyurethane copolymers derived from 4,4'-methylenediphenyl diisocyanate (MDI), 1,4-butanediol (BD) and alpha, omega-dihydroxy-[poly(caprolactone)-poly (dimethylsiloxane)-poly(caprolactone)] (a, x-dihydroxy( PCL-PDMS-PCL); (M) over bar (n) 6100 g mol(-1)) were synthesized by a two-step polyaddition reaction in solution. In the synthesis of the polyurethanes, the PCL blocks served as a compatibilizer between the nonpolar PDMS blocks and the polar comonomers, MDI and BD. The synthesis of thermoplastic polyurethanes (TPU) with high soft segment contents was optimized in terms of the concentrations of the reactants, the molar ratio of the NCO/OH groups, and the time and temperature of the polyaddition reaction. The structure, composition, and hard MDI/BD segment length of the synthesized polyurethane copolymers were determined by H-1, C-13-NMR, and two-dimensional correlation (COSY, HSQC, and HMBC) spectroscopy, while the hydrogen bonding interactions in the copolymers were analyzed by FT-IR spectroscopy. The influence of the reaction conditions on the structure, molecular weight, thermal, and some physical properties was studied at constant composition of the reaction mixture. A change in the molar ratio of the NCO/OH groups and the reaction conditions modified not only the molecular weight of the synthesized polyurethanes, but also the microstructure and therefore the thermal and physical properties of the copolymers. It was demonstrated that only PCL segments with high soft segment contents crystallize, thereby showing spherulitic morphology.
PB  - Wiley-Blackwell, Malden
T2  - Journal of Applied Polymer Science
T1  - Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments
VL  - 122
IS  - 4
SP  - 2715
EP  - 2730
DO  - 10.1002/app.33926
ER  - 

@article{
author = "Pergal, Marija and Antić, Vesna and Govedarica, Milutin and Gođevac, Dejan and Ostojić, Sanja and Đonlagić, Jasna",
year = "2011",
abstract = "Novel polyurethane copolymers derived from 4,4'-methylenediphenyl diisocyanate (MDI), 1,4-butanediol (BD) and alpha, omega-dihydroxy-[poly(caprolactone)-poly (dimethylsiloxane)-poly(caprolactone)] (a, x-dihydroxy( PCL-PDMS-PCL); (M) over bar (n) 6100 g mol(-1)) were synthesized by a two-step polyaddition reaction in solution. In the synthesis of the polyurethanes, the PCL blocks served as a compatibilizer between the nonpolar PDMS blocks and the polar comonomers, MDI and BD. The synthesis of thermoplastic polyurethanes (TPU) with high soft segment contents was optimized in terms of the concentrations of the reactants, the molar ratio of the NCO/OH groups, and the time and temperature of the polyaddition reaction. The structure, composition, and hard MDI/BD segment length of the synthesized polyurethane copolymers were determined by H-1, C-13-NMR, and two-dimensional correlation (COSY, HSQC, and HMBC) spectroscopy, while the hydrogen bonding interactions in the copolymers were analyzed by FT-IR spectroscopy. The influence of the reaction conditions on the structure, molecular weight, thermal, and some physical properties was studied at constant composition of the reaction mixture. A change in the molar ratio of the NCO/OH groups and the reaction conditions modified not only the molecular weight of the synthesized polyurethanes, but also the microstructure and therefore the thermal and physical properties of the copolymers. It was demonstrated that only PCL segments with high soft segment contents crystallize, thereby showing spherulitic morphology.",
publisher = "Wiley-Blackwell, Malden",
journal = "Journal of Applied Polymer Science",
title = "Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments",
volume = "122",
number = "4",
pages = "2715-2730",
doi = "10.1002/app.33926"
}

Pergal, M., Antić, V., Govedarica, M., Gođevac, D., Ostojić, S.,& Đonlagić, J.. (2011). Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments. in Journal of Applied Polymer Science
Wiley-Blackwell, Malden., 122(4), 2715-2730.
https://doi.org/10.1002/app.33926

Pergal M, Antić V, Govedarica M, Gođevac D, Ostojić S, Đonlagić J. Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments. in Journal of Applied Polymer Science. 2011;122(4):2715-2730.
doi:10.1002/app.33926 .

Pergal, Marija, Antić, Vesna, Govedarica, Milutin, Gođevac, Dejan, Ostojić, Sanja, Đonlagić, Jasna, "Synthesis and Characterization of Novel Urethane-Siloxane Copolymers with a High Content of PCL-PDMS-PCL Segments" in Journal of Applied Polymer Science, 122, no. 4 (2011):2715-2730,
https://doi.org/10.1002/app.33926 . .

TY  - JOUR
AU  - Antić, Vesna
AU  - Pergal, Marija
AU  - Govedarica, Milutin
AU  - Antić, Mališa
AU  - Đonlagić, Jasna
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/630
AB  - A series of novel thermoplastic elastomers, based on poly(butylene terephthalate) (PBT) and polycaprolactone-block-polydimethylsiloxane-b/ock-polycaprolactone (PCL-PDMS-PCL), with various mass fractions, were synthesized through melt polycondensation. In the synthesis of the poly(ester-siloxane)s, the PCL blocks served as a compatibilizer for the non-polar PDMS blocks and the polar comonomers dimethyl terephthalate and 1,4-butanediol. The introduction of PCL-PDMS-PCL soft segments resulted in an improvement of the miscibility of the reaction mixture and therefore in higher molecular weight polymers. The content of hard PBT segments in the polymer chains was varied from 10 to 80 mass%. The degree of crystallinity of the poly(ester-siloxane)s was determined using differential scanning calorimetry and wide-angle X-ray scattering. The introduction of PCL-PDMS-PCL soft segments into the polymer main chains reduced the crystallinity of the hard segments and altered related properties such as melting temperature and storage modulus, and also modified the surface properties. The thermal stability of the poly(ester-siloxane)s was higher than that of the PBT homopolymer. The inclusion of the siloxane prepolymer with terminal PCL into the macromolecular chains increased the molecular weight of the copolymers, the homogeneity of the samples in terms of composition and structure and the thermal stability. It also resulted in mechanical properties which could be tailored.
PB  - Wiley, Hoboken
T2  - Polymer International
T1  - Copolymers based on poly(butylene terephthalate) and polycaprolactone-block-polydimethylsiloxane-block-polycaprolactone
VL  - 59
IS  - 6
SP  - 796
EP  - 807
DO  - 10.1002/pi.2791
ER  - 

@article{
author = "Antić, Vesna and Pergal, Marija and Govedarica, Milutin and Antić, Mališa and Đonlagić, Jasna",
year = "2010",
abstract = "A series of novel thermoplastic elastomers, based on poly(butylene terephthalate) (PBT) and polycaprolactone-block-polydimethylsiloxane-b/ock-polycaprolactone (PCL-PDMS-PCL), with various mass fractions, were synthesized through melt polycondensation. In the synthesis of the poly(ester-siloxane)s, the PCL blocks served as a compatibilizer for the non-polar PDMS blocks and the polar comonomers dimethyl terephthalate and 1,4-butanediol. The introduction of PCL-PDMS-PCL soft segments resulted in an improvement of the miscibility of the reaction mixture and therefore in higher molecular weight polymers. The content of hard PBT segments in the polymer chains was varied from 10 to 80 mass%. The degree of crystallinity of the poly(ester-siloxane)s was determined using differential scanning calorimetry and wide-angle X-ray scattering. The introduction of PCL-PDMS-PCL soft segments into the polymer main chains reduced the crystallinity of the hard segments and altered related properties such as melting temperature and storage modulus, and also modified the surface properties. The thermal stability of the poly(ester-siloxane)s was higher than that of the PBT homopolymer. The inclusion of the siloxane prepolymer with terminal PCL into the macromolecular chains increased the molecular weight of the copolymers, the homogeneity of the samples in terms of composition and structure and the thermal stability. It also resulted in mechanical properties which could be tailored.",
publisher = "Wiley, Hoboken",
journal = "Polymer International",
title = "Copolymers based on poly(butylene terephthalate) and polycaprolactone-block-polydimethylsiloxane-block-polycaprolactone",
volume = "59",
number = "6",
pages = "796-807",
doi = "10.1002/pi.2791"
}

Antić, V., Pergal, M., Govedarica, M., Antić, M.,& Đonlagić, J.. (2010). Copolymers based on poly(butylene terephthalate) and polycaprolactone-block-polydimethylsiloxane-block-polycaprolactone. in Polymer International
Wiley, Hoboken., 59(6), 796-807.
https://doi.org/10.1002/pi.2791

Antić V, Pergal M, Govedarica M, Antić M, Đonlagić J. Copolymers based on poly(butylene terephthalate) and polycaprolactone-block-polydimethylsiloxane-block-polycaprolactone. in Polymer International. 2010;59(6):796-807.
doi:10.1002/pi.2791 .

Antić, Vesna, Pergal, Marija, Govedarica, Milutin, Antić, Mališa, Đonlagić, Jasna, "Copolymers based on poly(butylene terephthalate) and polycaprolactone-block-polydimethylsiloxane-block-polycaprolactone" in Polymer International, 59, no. 6 (2010):796-807,
https://doi.org/10.1002/pi.2791 . .

TY  - JOUR
AU  - Antić, Vesna
AU  - Pergal, Marija
AU  - Antić, Mališa
AU  - Đonlagić, Jasna
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/727
AB  - Two series of thermoplastic elastomers (TPES), based on poly(dimethylsiloxane) (PDMS) as the soft segment and poly(butylene terephthalate) (PBT) as the hard segment, were analyzed by dynamic mechanical spectroscopy. In the first TPES series the lengths of both hard and soft segments were varied while the mass ratio of the hard to soft segments was nearly constant (about 60 mass%). In the second series, the mass ratio of hard and soft segments was varied in the range from 60/40 to 40/60, with a constant length of soft PDMS segments. The influence of the structure and composition of TPESs on the rheological properties, such as complex dynamic viscosity, μ*, the storage, G', and loss, G', shear modulus as well as the microphase separation transition temperature, TMST, was examined. The obtained results showed that the storage modulus of the TPESs increased in a rubbery plateau region with increase in degree of crystallinity. The rheological measurements of TPESs also showed that a microphase reorganization occurred during the melting process. The microphase separation transition temperatures were in the range from 220 to 234°C. In the isotropic molten state, the complex dynamic viscosity increased with increasing both the content and length of hard PBT segments.
AB  - Dve serije termoplastičnih elastomera (TPES) na bazi poli(dimetilsiloksana) kao mekog segmenta i poli(butilentereftalata) kao tvrdog segmenta su analizirane dinamičko-mehaničkom spektroskopijom. U prvoj TPES seriji varirane su dužine tvrdih i mekih segmenata dok je njihov maseni odnos bio skoro konstantan (oko 60 mas%). U drugoj seriji, odnos tvrdih i mekih segmenata je variran u opsegu od 60/40 do 40/60, dok je dužina mekih PDMS segmenata bila konstantna. Ispitan je uticaj strukture i sastava TPES kopolimera na reološka svojstva, kao što su kompleksni dinamički viskozitet, μ*, moduli sačuvane, G', i izgubljene energije, G', i temperatura mikrofaznog razdvajanja, TMST. Dobijeni rezultati su pokazali da su uzorci sa većim stepenom kristaliničnosti imali i veće module sačuvane energije u gumolikom platou. Reološka merenja su takođe pokazala da svi TPES uzorci ispoljavaju mikrofaznu reorganizaciju u procesu topljenja. Temperature mikrofaznog razdvajanja su bile u opsegu od 220 do 234°C. U izotropskom rastopu, kompleksni dinamički viskoziteti su rasli sa povećanjem sadržaja i dužine PBT segmenata.
PB  - Association of Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Rheological behaviour of thermoplastic poly(ester-siloxane)s
T1  - Reološko ponašanje termoplastičnih poli(estar-siloksana)
VL  - 64
IS  - 6
SP  - 537
EP  - 545
DO  - 10.2298/HEMIND101015067A
ER  - 

@article{
author = "Antić, Vesna and Pergal, Marija and Antić, Mališa and Đonlagić, Jasna",
year = "2010",
abstract = "Two series of thermoplastic elastomers (TPES), based on poly(dimethylsiloxane) (PDMS) as the soft segment and poly(butylene terephthalate) (PBT) as the hard segment, were analyzed by dynamic mechanical spectroscopy. In the first TPES series the lengths of both hard and soft segments were varied while the mass ratio of the hard to soft segments was nearly constant (about 60 mass%). In the second series, the mass ratio of hard and soft segments was varied in the range from 60/40 to 40/60, with a constant length of soft PDMS segments. The influence of the structure and composition of TPESs on the rheological properties, such as complex dynamic viscosity, μ*, the storage, G', and loss, G', shear modulus as well as the microphase separation transition temperature, TMST, was examined. The obtained results showed that the storage modulus of the TPESs increased in a rubbery plateau region with increase in degree of crystallinity. The rheological measurements of TPESs also showed that a microphase reorganization occurred during the melting process. The microphase separation transition temperatures were in the range from 220 to 234°C. In the isotropic molten state, the complex dynamic viscosity increased with increasing both the content and length of hard PBT segments., Dve serije termoplastičnih elastomera (TPES) na bazi poli(dimetilsiloksana) kao mekog segmenta i poli(butilentereftalata) kao tvrdog segmenta su analizirane dinamičko-mehaničkom spektroskopijom. U prvoj TPES seriji varirane su dužine tvrdih i mekih segmenata dok je njihov maseni odnos bio skoro konstantan (oko 60 mas%). U drugoj seriji, odnos tvrdih i mekih segmenata je variran u opsegu od 60/40 do 40/60, dok je dužina mekih PDMS segmenata bila konstantna. Ispitan je uticaj strukture i sastava TPES kopolimera na reološka svojstva, kao što su kompleksni dinamički viskozitet, μ*, moduli sačuvane, G', i izgubljene energije, G', i temperatura mikrofaznog razdvajanja, TMST. Dobijeni rezultati su pokazali da su uzorci sa većim stepenom kristaliničnosti imali i veće module sačuvane energije u gumolikom platou. Reološka merenja su takođe pokazala da svi TPES uzorci ispoljavaju mikrofaznu reorganizaciju u procesu topljenja. Temperature mikrofaznog razdvajanja su bile u opsegu od 220 do 234°C. U izotropskom rastopu, kompleksni dinamički viskoziteti su rasli sa povećanjem sadržaja i dužine PBT segmenata.",
publisher = "Association of Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Rheological behaviour of thermoplastic poly(ester-siloxane)s, Reološko ponašanje termoplastičnih poli(estar-siloksana)",
volume = "64",
number = "6",
pages = "537-545",
doi = "10.2298/HEMIND101015067A"
}

Antić, V., Pergal, M., Antić, M.,& Đonlagić, J.. (2010). Rheological behaviour of thermoplastic poly(ester-siloxane)s. in Hemijska industrija
Association of Chemical Engineers of Serbia., 64(6), 537-545.
https://doi.org/10.2298/HEMIND101015067A

Antić V, Pergal M, Antić M, Đonlagić J. Rheological behaviour of thermoplastic poly(ester-siloxane)s. in Hemijska industrija. 2010;64(6):537-545.
doi:10.2298/HEMIND101015067A .

Antić, Vesna, Pergal, Marija, Antić, Mališa, Đonlagić, Jasna, "Rheological behaviour of thermoplastic poly(ester-siloxane)s" in Hemijska industrija, 64, no. 6 (2010):537-545,
https://doi.org/10.2298/HEMIND101015067A . .

TY  - JOUR
AU  - Vučković, Marija V.
AU  - Antić, Vesna
AU  - Govedarica, Milutin
AU  - Đonlagić, Jasna
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3177
AB  - A series of thermoplastic elastomers based on ethylene oxide- poly(dimethylsiloxane)-ethylene oxide (EO-PDMS-EO), as the soft segment, and poly(butylene terephthalate) (PBT), as the hard segment, were synthesized by catalyzed two-step, melt transesterification reaction of dimethyl terephthalate (DMT) with 1, 4-butanediol (BD) and α, ω-dihydroxy-(EO-PDMS-EO). Copolymers with a content of hard PBT segments between 40 and 90 mass % and a constant length of the soft EO-PDMS-EO segments were prepared. The siloxane prepolymer with hydrophilic terminal EO units was used to improve the miscibility between the polar comonomers, DMT and BD, and the nonpolar PDMS. The molecular structure and composition of the copolymers were determined by 1HNMR spectroscopy, whereas the effectiveness of the incorporation of α, ω-dihydroxy-(EO-PDMS-EO) into the copolymer chains was verified by chloroform extraction. The effects of the structure and composition of the copolymers on the melting temperatures and the degree of crystallinity, as well as on the thermal degradation stability and some rheological properties, were studied. It was demonstrated that the degree of crystallinity, the melting and crystallization temperatures of the copolymers increased with increasing mass fraction of the PBT segments. The thermal stability of the copolymers was lower than that of PBT homopolymer, because of the presence of thermoliable ether bonds in the soft segments.
PB  - Wiley
T2  - Journal of Applied Polymer Science
T1  - Synthesis and characterization of copolymers based on poly(butylene terephthalate) and ethylene oxide-poly(dimethylsiloxane)-ethylene oxide
VL  - 115
IS  - 6
SP  - 3205
EP  - 3216
DO  - 10.1002/app.31416
ER  - 

@article{
author = "Vučković, Marija V. and Antić, Vesna and Govedarica, Milutin and Đonlagić, Jasna",
year = "2010",
abstract = "A series of thermoplastic elastomers based on ethylene oxide- poly(dimethylsiloxane)-ethylene oxide (EO-PDMS-EO), as the soft segment, and poly(butylene terephthalate) (PBT), as the hard segment, were synthesized by catalyzed two-step, melt transesterification reaction of dimethyl terephthalate (DMT) with 1, 4-butanediol (BD) and α, ω-dihydroxy-(EO-PDMS-EO). Copolymers with a content of hard PBT segments between 40 and 90 mass % and a constant length of the soft EO-PDMS-EO segments were prepared. The siloxane prepolymer with hydrophilic terminal EO units was used to improve the miscibility between the polar comonomers, DMT and BD, and the nonpolar PDMS. The molecular structure and composition of the copolymers were determined by 1HNMR spectroscopy, whereas the effectiveness of the incorporation of α, ω-dihydroxy-(EO-PDMS-EO) into the copolymer chains was verified by chloroform extraction. The effects of the structure and composition of the copolymers on the melting temperatures and the degree of crystallinity, as well as on the thermal degradation stability and some rheological properties, were studied. It was demonstrated that the degree of crystallinity, the melting and crystallization temperatures of the copolymers increased with increasing mass fraction of the PBT segments. The thermal stability of the copolymers was lower than that of PBT homopolymer, because of the presence of thermoliable ether bonds in the soft segments.",
publisher = "Wiley",
journal = "Journal of Applied Polymer Science",
title = "Synthesis and characterization of copolymers based on poly(butylene terephthalate) and ethylene oxide-poly(dimethylsiloxane)-ethylene oxide",
volume = "115",
number = "6",
pages = "3205-3216",
doi = "10.1002/app.31416"
}

Vučković, M. V., Antić, V., Govedarica, M.,& Đonlagić, J.. (2010). Synthesis and characterization of copolymers based on poly(butylene terephthalate) and ethylene oxide-poly(dimethylsiloxane)-ethylene oxide. in Journal of Applied Polymer Science
Wiley., 115(6), 3205-3216.
https://doi.org/10.1002/app.31416

Vučković MV, Antić V, Govedarica M, Đonlagić J. Synthesis and characterization of copolymers based on poly(butylene terephthalate) and ethylene oxide-poly(dimethylsiloxane)-ethylene oxide. in Journal of Applied Polymer Science. 2010;115(6):3205-3216.
doi:10.1002/app.31416 .

Vučković, Marija V., Antić, Vesna, Govedarica, Milutin, Đonlagić, Jasna, "Synthesis and characterization of copolymers based on poly(butylene terephthalate) and ethylene oxide-poly(dimethylsiloxane)-ethylene oxide" in Journal of Applied Polymer Science, 115, no. 6 (2010):3205-3216,
https://doi.org/10.1002/app.31416 . .

TY  - JOUR
AU  - Vučković, Marija V.
AU  - Antić, Vesna
AU  - Dojčinović, Biljana
AU  - Govedarica, Milutin
AU  - Đonlagić, Jasna
PY  - 2006
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5715
AB  - A series of novel thermoplastic elastomers based on ABA-type triblock prepolymers, poly[(propylene oxide)–(dimethylsiloxane)–(propylene oxide)] (PPO-PDMS-PPO), as the soft segments, and poly(butylene terephthalate) (PBT), as the hard segments, was synthesized by catalyzed two-step melt transesterification of dimethyl terephthalate (DMT) with 1,4-butanediol (BD) and α,ω-dihydroxy-(PPO-PDMS-PPO) (Mn = 2930 g mol−1). Several copolymers with a content of hard PBT segments between 40 and 60 mass% and a constant length of the soft PPO-PDMS-PPO segments were prepared. The siloxane-containing triblock prepolymer with
hydrophilic terminal PPO blocks was used to improve the compatibility between the polar comonomers, i.e. DMT and BD, and the non-polar PDMS segments. The structure and composition of the copolymers were examined using 1H NMR spectroscopy, while the effectiveness of the incorporation of α,ω-dihydroxy-(PPO-PDMS-PPO) prepolymer into the copolyester chains was controlled by chloroform extraction. The effect of the structure and
composition of the copolymers on the transition temperatures (Tm and Tg) and the thermal and thermo-oxidative degradation stability, as well as on the degree of crystallinity, and some rheological properties, were studied.
PB  - Wiley
T2  - Polymer International
T1  - Synthesis and characterization of poly(ester ether siloxane)s
VL  - 55
IS  - 11
SP  - 1304
EP  - 1314
DO  - 10.1002/pi.2085
ER  - 

@article{
author = "Vučković, Marija V. and Antić, Vesna and Dojčinović, Biljana and Govedarica, Milutin and Đonlagić, Jasna",
year = "2006",
abstract = "A series of novel thermoplastic elastomers based on ABA-type triblock prepolymers, poly[(propylene oxide)–(dimethylsiloxane)–(propylene oxide)] (PPO-PDMS-PPO), as the soft segments, and poly(butylene terephthalate) (PBT), as the hard segments, was synthesized by catalyzed two-step melt transesterification of dimethyl terephthalate (DMT) with 1,4-butanediol (BD) and α,ω-dihydroxy-(PPO-PDMS-PPO) (Mn = 2930 g mol−1). Several copolymers with a content of hard PBT segments between 40 and 60 mass% and a constant length of the soft PPO-PDMS-PPO segments were prepared. The siloxane-containing triblock prepolymer with
hydrophilic terminal PPO blocks was used to improve the compatibility between the polar comonomers, i.e. DMT and BD, and the non-polar PDMS segments. The structure and composition of the copolymers were examined using 1H NMR spectroscopy, while the effectiveness of the incorporation of α,ω-dihydroxy-(PPO-PDMS-PPO) prepolymer into the copolyester chains was controlled by chloroform extraction. The effect of the structure and
composition of the copolymers on the transition temperatures (Tm and Tg) and the thermal and thermo-oxidative degradation stability, as well as on the degree of crystallinity, and some rheological properties, were studied.",
publisher = "Wiley",
journal = "Polymer International",
title = "Synthesis and characterization of poly(ester ether siloxane)s",
volume = "55",
number = "11",
pages = "1304-1314",
doi = "10.1002/pi.2085"
}

Vučković, M. V., Antić, V., Dojčinović, B., Govedarica, M.,& Đonlagić, J.. (2006). Synthesis and characterization of poly(ester ether siloxane)s. in Polymer International
Wiley., 55(11), 1304-1314.
https://doi.org/10.1002/pi.2085

Vučković MV, Antić V, Dojčinović B, Govedarica M, Đonlagić J. Synthesis and characterization of poly(ester ether siloxane)s. in Polymer International. 2006;55(11):1304-1314.
doi:10.1002/pi.2085 .

Vučković, Marija V., Antić, Vesna, Dojčinović, Biljana, Govedarica, Milutin, Đonlagić, Jasna, "Synthesis and characterization of poly(ester ether siloxane)s" in Polymer International, 55, no. 11 (2006):1304-1314,
https://doi.org/10.1002/pi.2085 . .

TY  - JOUR
AU  - Dojčinović, Biljana
AU  - Antić, Vesna
AU  - Vučković, Marija V.
AU  - Đonlagić, Jasna
PY  - 2005
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/216
AB  - Two series of thermoplastic elastomers, based on poly(dimethylsiloxane) PDMS, as the soft segment and poly(butylene terephthalate), PBT, as the hard segment, were synthesized by catalyzed transesterification, from dimethyl terephthalate, DMT, silanol-terminated poly(dimethylsiloxane), PDMS-OH Mn=1750g/mol, and 1,4-butanediol, BD. The mole ratio of the starting comonomers was selected to result in a constant hard to soft weight ratio of 55:45. The first series was synthesized in order to determine the optimal mole ratio of BD and DMT for the synthesis of high molecular weight thermoplastic poly(ester-siloxane)s, TPESs. The second series was performed in the presence of the high-boiling solvent, 1,2,4-trichlorbenzene in order to increase the mixing between the extremely non-polar siloxane prepolymer and the polar reactants, DMT and BD, and, therefore, avoid phase separation during synthesis. The structure and composition of the synthesized poly(ester-siloxane)s were verified by 1H-NMR spectroscopy, while the melting temperatures and degree of crystallinity were determined by differential scanning calorimetry (DSC). The effectiveness of the incorporation of the silanol-terminated poly( dimethylsiloxane) into the polyester chains was verified by chloroform extraction. The rheological properties of the poly(ester-siloxane)s were investigated by dynamic mechanical spectroscopy (DMA).
AB  - Dve serije termoplastičnih elastomera na bazi poli(dimetilsiloksana) kao mekog segmenta i poli(butilentereftalata) kao tvrdog segmenta sintetisane su katalizovanom transesterifikacijom polazeći od dimetiltereftalata, DMT silanol-terminarnog poli(dimetil-siloksana), PDMS-OH, Mn=1750g/mol i 1,4-butandiola, BD. Molski odnos početnih komonomera odabran je tako da je rezultovao u konstantnom masenom odnosu tvrdih i mekih segmenata od 55:45. Prva serija je sintetisana sa ciljem da se odredi optimalan molski odnos komonomera BD i DMT za dobijanje termoplastičnih elastomera velikih molarnih masa. U drugoj seriji sinteze su izvođene u prisustvu teško isparljivog rastvarača 1,2,4-trihlorbenzena sa ciljem da se poveća mešljivost izuzetno nepolarnog poli(dimetilsiloksanskog)pretpolimera i polarnih reaktanata, kao što su DMT i BD i samim tim da se izbegne fazna separacija u reakcionoj smeši tokom sinteze. Struktura i sastav sintetisanih poli(estar-siloksana) potvrđeni su 1H-NMR spektroskopijom, dok su temperatura topljenja i stepen kristaliničnosti određeni diferencijalnom skenirajućom kalometrijom (DSC). Efikasnost ugradnje silanol-terminiranog poli(dimetilsiloksana) u poliestarske lance utvrđena je na osnovu ekstrakcije hloroformom. Reološka svojstva poli(estara-siloksana) ispitana su dinamičko-mehaničkom spektroskopijom.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Synthesis of thermoplastic poly(ester-siloxane)s in the melt and in solution
T1  - Sinteza termoplastičnih poli(estar-siloksana) u rastopu i rastvoru
VL  - 70
IS  - 12
SP  - 1469
EP  - 1485
DO  - 10.2298/JSC0512469D
ER  - 

@article{
author = "Dojčinović, Biljana and Antić, Vesna and Vučković, Marija V. and Đonlagić, Jasna",
year = "2005",
abstract = "Two series of thermoplastic elastomers, based on poly(dimethylsiloxane) PDMS, as the soft segment and poly(butylene terephthalate), PBT, as the hard segment, were synthesized by catalyzed transesterification, from dimethyl terephthalate, DMT, silanol-terminated poly(dimethylsiloxane), PDMS-OH Mn=1750g/mol, and 1,4-butanediol, BD. The mole ratio of the starting comonomers was selected to result in a constant hard to soft weight ratio of 55:45. The first series was synthesized in order to determine the optimal mole ratio of BD and DMT for the synthesis of high molecular weight thermoplastic poly(ester-siloxane)s, TPESs. The second series was performed in the presence of the high-boiling solvent, 1,2,4-trichlorbenzene in order to increase the mixing between the extremely non-polar siloxane prepolymer and the polar reactants, DMT and BD, and, therefore, avoid phase separation during synthesis. The structure and composition of the synthesized poly(ester-siloxane)s were verified by 1H-NMR spectroscopy, while the melting temperatures and degree of crystallinity were determined by differential scanning calorimetry (DSC). The effectiveness of the incorporation of the silanol-terminated poly( dimethylsiloxane) into the polyester chains was verified by chloroform extraction. The rheological properties of the poly(ester-siloxane)s were investigated by dynamic mechanical spectroscopy (DMA)., Dve serije termoplastičnih elastomera na bazi poli(dimetilsiloksana) kao mekog segmenta i poli(butilentereftalata) kao tvrdog segmenta sintetisane su katalizovanom transesterifikacijom polazeći od dimetiltereftalata, DMT silanol-terminarnog poli(dimetil-siloksana), PDMS-OH, Mn=1750g/mol i 1,4-butandiola, BD. Molski odnos početnih komonomera odabran je tako da je rezultovao u konstantnom masenom odnosu tvrdih i mekih segmenata od 55:45. Prva serija je sintetisana sa ciljem da se odredi optimalan molski odnos komonomera BD i DMT za dobijanje termoplastičnih elastomera velikih molarnih masa. U drugoj seriji sinteze su izvođene u prisustvu teško isparljivog rastvarača 1,2,4-trihlorbenzena sa ciljem da se poveća mešljivost izuzetno nepolarnog poli(dimetilsiloksanskog)pretpolimera i polarnih reaktanata, kao što su DMT i BD i samim tim da se izbegne fazna separacija u reakcionoj smeši tokom sinteze. Struktura i sastav sintetisanih poli(estar-siloksana) potvrđeni su 1H-NMR spektroskopijom, dok su temperatura topljenja i stepen kristaliničnosti određeni diferencijalnom skenirajućom kalometrijom (DSC). Efikasnost ugradnje silanol-terminiranog poli(dimetilsiloksana) u poliestarske lance utvrđena je na osnovu ekstrakcije hloroformom. Reološka svojstva poli(estara-siloksana) ispitana su dinamičko-mehaničkom spektroskopijom.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis of thermoplastic poly(ester-siloxane)s in the melt and in solution, Sinteza termoplastičnih poli(estar-siloksana) u rastopu i rastvoru",
volume = "70",
number = "12",
pages = "1469-1485",
doi = "10.2298/JSC0512469D"
}

Dojčinović, B., Antić, V., Vučković, M. V.,& Đonlagić, J.. (2005). Synthesis of thermoplastic poly(ester-siloxane)s in the melt and in solution. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 70(12), 1469-1485.
https://doi.org/10.2298/JSC0512469D

Dojčinović B, Antić V, Vučković MV, Đonlagić J. Synthesis of thermoplastic poly(ester-siloxane)s in the melt and in solution. in Journal of the Serbian Chemical Society. 2005;70(12):1469-1485.
doi:10.2298/JSC0512469D .

Dojčinović, Biljana, Antić, Vesna, Vučković, Marija V., Đonlagić, Jasna, "Synthesis of thermoplastic poly(ester-siloxane)s in the melt and in solution" in Journal of the Serbian Chemical Society, 70, no. 12 (2005):1469-1485,
https://doi.org/10.2298/JSC0512469D . .