TY  - PAT
AU  - Josić, Djuro
AU  - Begić, Marija
AU  - Andjelković, Uroš
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6940
AB  - A process for the purification of Prothrombin Complex Concentrate (PCC) from complete plasma or cryo-poor plasma using chromatography, the method comprising performing an initial sample displacement chromatography step of complete plasma or cryo-poor plasma, in particular undiluted cryo-poor plasma, on an anion exchanger to obtain a first fraction enriched in PCC.A fraction comprising PCC and factor IX obtainable by the process of the invention.
PB  - European Patent Office
T2  - European patent office
T1  - A process for the purification of prothrombin complex concentrate (PCC) and FIX from complete plasma or cryo-poor plasma
IS  - EP3945095A1
UR  - https://hdl.handle.net/21.15107/rcub_cer_6940
ER  - 

@misc{
author = "Josić, Djuro and Begić, Marija and Andjelković, Uroš",
year = "2022",
abstract = "A process for the purification of Prothrombin Complex Concentrate (PCC) from complete plasma or cryo-poor plasma using chromatography, the method comprising performing an initial sample displacement chromatography step of complete plasma or cryo-poor plasma, in particular undiluted cryo-poor plasma, on an anion exchanger to obtain a first fraction enriched in PCC.A fraction comprising PCC and factor IX obtainable by the process of the invention.",
publisher = "European Patent Office",
journal = "European patent office",
title = "A process for the purification of prothrombin complex concentrate (PCC) and FIX from complete plasma or cryo-poor plasma",
number = "EP3945095A1",
url = "https://hdl.handle.net/21.15107/rcub_cer_6940"
}

Josić, D., Begić, M.,& Andjelković, U.. (2022). A process for the purification of prothrombin complex concentrate (PCC) and FIX from complete plasma or cryo-poor plasma. in European patent office
European Patent Office.(EP3945095A1).
https://hdl.handle.net/21.15107/rcub_cer_6940

Josić D, Begić M, Andjelković U. A process for the purification of prothrombin complex concentrate (PCC) and FIX from complete plasma or cryo-poor plasma. in European patent office. 2022;(EP3945095A1).
https://hdl.handle.net/21.15107/rcub_cer_6940 .

Josić, Djuro, Begić, Marija, Andjelković, Uroš, "A process for the purification of prothrombin complex concentrate (PCC) and FIX from complete plasma or cryo-poor plasma" in European patent office, no. EP3945095A1 (2022),
https://hdl.handle.net/21.15107/rcub_cer_6940 .

TY  - JOUR
AU  - Srajer-Gajdošik, Martina
AU  - Anđelković, Uroš
AU  - Gašo Sokač, Dajana
AU  - Pavlović, Hrvoje
AU  - Shevchuk, Olga
AU  - Martinović, Tamara
AU  - Clifton, James
AU  - Begić, Marija
AU  - Josić, Djuro
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6923
AB  - Proteomic analysis of foodborne pathogen Listeria monocytogenes after treatment with three disinfectants based on ammonium salts of pyridoxal oxime (POD) reveal perturbation of cellular processes. These inhibitors caused disturbance in the synthesis of plasma membrane proteins and cell wall proteoglycans. Some of key proteins and proteoglycans from these two groups that are important for bacterial growth are down-regulated. Additionally, we demonstrated that the main bacterial toxin Listeriolysin O (LLO) is significantly down-regulated after treatment with each of three investigated inhibitors. These investigations confirm already postulated mechanism of action of POD-based inhibitors that results in disturbance of key cell surface proteins and proteoglycans in Gram-positive bacteria. Additionally, the use of some proteins such as LLO, as potential biomarker candidates of food poisoning with this bacterium is discussed.
PB  - Elsevier
T2  - Food Research International
T1  - Proteomic analysis of pyridoxal oxime derivatives treated Listeria monocytogenes reveals down-regulation of the main virulence factor, Listeriolysin O
VL  - 131
SP  - 108951
DO  - 10.1016/j.foodres.2019.108951
ER  - 

@article{
author = "Srajer-Gajdošik, Martina and Anđelković, Uroš and Gašo Sokač, Dajana and Pavlović, Hrvoje and Shevchuk, Olga and Martinović, Tamara and Clifton, James and Begić, Marija and Josić, Djuro",
year = "2020",
abstract = "Proteomic analysis of foodborne pathogen Listeria monocytogenes after treatment with three disinfectants based on ammonium salts of pyridoxal oxime (POD) reveal perturbation of cellular processes. These inhibitors caused disturbance in the synthesis of plasma membrane proteins and cell wall proteoglycans. Some of key proteins and proteoglycans from these two groups that are important for bacterial growth are down-regulated. Additionally, we demonstrated that the main bacterial toxin Listeriolysin O (LLO) is significantly down-regulated after treatment with each of three investigated inhibitors. These investigations confirm already postulated mechanism of action of POD-based inhibitors that results in disturbance of key cell surface proteins and proteoglycans in Gram-positive bacteria. Additionally, the use of some proteins such as LLO, as potential biomarker candidates of food poisoning with this bacterium is discussed.",
publisher = "Elsevier",
journal = "Food Research International",
title = "Proteomic analysis of pyridoxal oxime derivatives treated Listeria monocytogenes reveals down-regulation of the main virulence factor, Listeriolysin O",
volume = "131",
pages = "108951",
doi = "10.1016/j.foodres.2019.108951"
}

Srajer-Gajdošik, M., Anđelković, U., Gašo Sokač, D., Pavlović, H., Shevchuk, O., Martinović, T., Clifton, J., Begić, M.,& Josić, D.. (2020). Proteomic analysis of pyridoxal oxime derivatives treated Listeria monocytogenes reveals down-regulation of the main virulence factor, Listeriolysin O. in Food Research International
Elsevier., 131, 108951.
https://doi.org/10.1016/j.foodres.2019.108951

Srajer-Gajdošik M, Anđelković U, Gašo Sokač D, Pavlović H, Shevchuk O, Martinović T, Clifton J, Begić M, Josić D. Proteomic analysis of pyridoxal oxime derivatives treated Listeria monocytogenes reveals down-regulation of the main virulence factor, Listeriolysin O. in Food Research International. 2020;131:108951.
doi:10.1016/j.foodres.2019.108951 .

Srajer-Gajdošik, Martina, Anđelković, Uroš, Gašo Sokač, Dajana, Pavlović, Hrvoje, Shevchuk, Olga, Martinović, Tamara, Clifton, James, Begić, Marija, Josić, Djuro, "Proteomic analysis of pyridoxal oxime derivatives treated Listeria monocytogenes reveals down-regulation of the main virulence factor, Listeriolysin O" in Food Research International, 131 (2020):108951,
https://doi.org/10.1016/j.foodres.2019.108951 . .