TY  - JOUR
AU  - Čobeljić, Božidar
AU  - Warzajtis, Beata
AU  - Rychlewska, Urszula
AU  - Radanović, Dušanka
AU  - Spasojević, Vojislav
AU  - Sladić, Dušan
AU  - Eshkourfu, Rabia
AU  - Anđelković, Katarina
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1041
AB  - A new malonic dihydrazide-based ligand, N',N'(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide (H(2)L3), has been prepared and characterized by elemental analysis, IR, C-13 NMR, and H-1 NMR spectroscopies. In the reaction of H(2)L3 with Ni(II) a binuclear complex has been obtained. The structure of the complex was established by X-ray analysis. Each Ni(II) is coordinated with two NNO donor sets from two ligand molecules in dianionic form (L3(2-)) forming an octahedral geometry. Multiple intramolecular C-H center dot center dot center dot pi (chelate ring) interactions support the molecular geometry of the [Ni-2(L3)(2)] complex. The structure of [Ni-2(L3)(2)] is compared with those of analogous Ni(II) complexes with pyridine dihydrazone type ligands. Magnetic behavior of the dinuclear complex was studied in temperature range of 2-300 K.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Journal of Coordination Chemistry
T1  - Synthesis and structure of a Ni(II) complex with N ',N '(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate
VL  - 65
IS  - 4
SP  - 655
EP  - 667
DO  - 10.1080/00958972.2012.658778
ER  - 

@article{
author = "Čobeljić, Božidar and Warzajtis, Beata and Rychlewska, Urszula and Radanović, Dušanka and Spasojević, Vojislav and Sladić, Dušan and Eshkourfu, Rabia and Anđelković, Katarina",
year = "2012",
abstract = "A new malonic dihydrazide-based ligand, N',N'(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide (H(2)L3), has been prepared and characterized by elemental analysis, IR, C-13 NMR, and H-1 NMR spectroscopies. In the reaction of H(2)L3 with Ni(II) a binuclear complex has been obtained. The structure of the complex was established by X-ray analysis. Each Ni(II) is coordinated with two NNO donor sets from two ligand molecules in dianionic form (L3(2-)) forming an octahedral geometry. Multiple intramolecular C-H center dot center dot center dot pi (chelate ring) interactions support the molecular geometry of the [Ni-2(L3)(2)] complex. The structure of [Ni-2(L3)(2)] is compared with those of analogous Ni(II) complexes with pyridine dihydrazone type ligands. Magnetic behavior of the dinuclear complex was studied in temperature range of 2-300 K.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Journal of Coordination Chemistry",
title = "Synthesis and structure of a Ni(II) complex with N ',N '(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate",
volume = "65",
number = "4",
pages = "655-667",
doi = "10.1080/00958972.2012.658778"
}

Čobeljić, B., Warzajtis, B., Rychlewska, U., Radanović, D., Spasojević, V., Sladić, D., Eshkourfu, R.,& Anđelković, K.. (2012). Synthesis and structure of a Ni(II) complex with N ',N '(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate. in Journal of Coordination Chemistry
Taylor & Francis Ltd, Abingdon., 65(4), 655-667.
https://doi.org/10.1080/00958972.2012.658778

Čobeljić B, Warzajtis B, Rychlewska U, Radanović D, Spasojević V, Sladić D, Eshkourfu R, Anđelković K. Synthesis and structure of a Ni(II) complex with N ',N '(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate. in Journal of Coordination Chemistry. 2012;65(4):655-667.
doi:10.1080/00958972.2012.658778 .

Čobeljić, Božidar, Warzajtis, Beata, Rychlewska, Urszula, Radanović, Dušanka, Spasojević, Vojislav, Sladić, Dušan, Eshkourfu, Rabia, Anđelković, Katarina, "Synthesis and structure of a Ni(II) complex with N ',N '(2)-bis[(1E)-1-(2-quinolyl)methylene]propanedihydrazide: multiple intramolecular CH center dot center dot center dot pi interactions between quinoline and quinolineimine chelate" in Journal of Coordination Chemistry, 65, no. 4 (2012):655-667,
https://doi.org/10.1080/00958972.2012.658778 . .

TY  - JOUR
AU  - Eshkourfu, Rabia
AU  - Čobeljić, Božidar
AU  - Vujčić, Miroslava
AU  - Turel, Iztok
AU  - Pevec, Andrej
AU  - Sepcic, Kristina
AU  - Zec, Manja
AU  - Radulovic, Sinisa
AU  - Srdic-Radic, Tatjana
AU  - Mitić, Dragana
AU  - Anđelković, Katarina
AU  - Sladić, Dušan
PY  - 2011
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/769
AB  - A novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide, N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide was synthesized and characterized by elemental analysis, spectroscopy (NMR and infrared), and X-ray crystal analysis. The complex showed a moderate activity towards Artemia salina. The highest cytotoxic potential of the complex was observed on the epithelial breast cancer (MDA-361) cell line. The investigated complex induced apoptosis, the early apoptotic cells comprising 28.18%, compared to 5.64% of control cells in the same phase. The interaction of the complex with calf thymus DNA (CT-DNA) was monitored by blue shift and hyperchromism in the UV-vis spectra. The observed intrinsic binding constant (K(b) = 4.2 x 10(5) M(-1)) together with structural analysis of the complex indicate the groove binding.
PB  - Elsevier Science Inc, New York
T2  - Journal of Inorganic Biochemistry
T1  - Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide
VL  - 105
IS  - 9
SP  - 1196
EP  - 1203
DO  - 10.1016/j.jinorgbio.2011.05.024
ER  - 

@article{
author = "Eshkourfu, Rabia and Čobeljić, Božidar and Vujčić, Miroslava and Turel, Iztok and Pevec, Andrej and Sepcic, Kristina and Zec, Manja and Radulovic, Sinisa and Srdic-Radic, Tatjana and Mitić, Dragana and Anđelković, Katarina and Sladić, Dušan",
year = "2011",
abstract = "A novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide, N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide was synthesized and characterized by elemental analysis, spectroscopy (NMR and infrared), and X-ray crystal analysis. The complex showed a moderate activity towards Artemia salina. The highest cytotoxic potential of the complex was observed on the epithelial breast cancer (MDA-361) cell line. The investigated complex induced apoptosis, the early apoptotic cells comprising 28.18%, compared to 5.64% of control cells in the same phase. The interaction of the complex with calf thymus DNA (CT-DNA) was monitored by blue shift and hyperchromism in the UV-vis spectra. The observed intrinsic binding constant (K(b) = 4.2 x 10(5) M(-1)) together with structural analysis of the complex indicate the groove binding.",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Inorganic Biochemistry",
title = "Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide",
volume = "105",
number = "9",
pages = "1196-1203",
doi = "10.1016/j.jinorgbio.2011.05.024"
}

Eshkourfu, R., Čobeljić, B., Vujčić, M., Turel, I., Pevec, A., Sepcic, K., Zec, M., Radulovic, S., Srdic-Radic, T., Mitić, D., Anđelković, K.,& Sladić, D.. (2011). Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide. in Journal of Inorganic Biochemistry
Elsevier Science Inc, New York., 105(9), 1196-1203.
https://doi.org/10.1016/j.jinorgbio.2011.05.024

Eshkourfu R, Čobeljić B, Vujčić M, Turel I, Pevec A, Sepcic K, Zec M, Radulovic S, Srdic-Radic T, Mitić D, Anđelković K, Sladić D. Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide. in Journal of Inorganic Biochemistry. 2011;105(9):1196-1203.
doi:10.1016/j.jinorgbio.2011.05.024 .

Eshkourfu, Rabia, Čobeljić, Božidar, Vujčić, Miroslava, Turel, Iztok, Pevec, Andrej, Sepcic, Kristina, Zec, Manja, Radulovic, Sinisa, Srdic-Radic, Tatjana, Mitić, Dragana, Anđelković, Katarina, Sladić, Dušan, "Synthesis, characterization, cytotoxic activity and DNA binding properties of the novel dinuclear cobalt(III) complex with the condensation product of 2-acetylpyridine and malonic acid dihydrazide" in Journal of Inorganic Biochemistry, 105, no. 9 (2011):1196-1203,
https://doi.org/10.1016/j.jinorgbio.2011.05.024 . .