Randjelović, Danijela

Link to this page

Authority KeyName Variants
orcid::0000-0003-0780-5058
  • Randjelović, Danijela (142)
  • Ranđelović, Danijela (2)
Projects
Micro- Nanosystems and Sensors for Electric Power and Process Industry and Environmental Protection Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM)
Development of micro- and nanosystems as carriers for drugs with anti-inflammatory effect and methods for their characterization Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200168 (University of Belgrade, Faculty of Chemistry)
Nanostructured Functional and Composite Materials in Catalytic and Sorption Processes Dynamics of nonlinear physicochemical and biochemical systems with modeling and predicting of their behavior under nonequilibrium conditions
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200161 (University of Belgrade, Faculty of Pharmacy) Behavioral ?ffects following repeated administration of newly synthesized ligands selective for distinct subtypes of GABAA receptor benzodiazepine binding site: comparison with standard psychopharmacologic drugs
Simultaneous Bioremediation and Soilification of Degraded Areas to Preserve Natural Resources of Biologically Active Substances, and Development and Production of Biomaterials and Dietetic Products Reinforcement of Regional Microsystems and Nanosystems Centre
Advanced technologies for monitoring and environmental protection from chemical pollutants and radiation burden Measurements in a smart grid concept
NanoCellEmoCog - Neuroimmune aspects of mood, anxiety and cognitive effects of leads/drug candidates acting at GABAA and/or sigma-2 receptors: In vitro/in vivo delineation by nano- and hiPSC-based platform Volkswagen Foundation within the framework of the project I/72 957
Innovative bio-inspired sensors and microfluidic devices for saliva-based theranostics of oral and systemic diseases Synthesis and characterization of novel functional polymers and polymeric nanocomposites
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200135 (University of Belgrade, Faculty of Technology and Metallurgy) Zero- to Three-Dimensional Nanostructures for Application in Electronics and Renewable Energy Sources: Synthesis, Characterization and Processing
Magnetic and radionuclide labeled nanostructured materials for medical applications 142-451-2168/2019-02
bilateral project between the Republic of Serbia and the Federal Republic of Germany (Biosurfactants and biopolysaccharides/film-forming polymers as cosmetic raw materials and prospective pharmaceutical excipients: formulation of colloidal and film-forming delivery systems) Bioplastech (BP2017)
COST Action FP1405 Federal Republic of Germany
Cell Cycle Aberrations and the Impact of Oxidative Stress in Neurodegenerative Processes and Malignant Transformation of the Cell Agrobiodiversity and land-use change in Serbia: an integrated biodiversity assessment of key functional groups of arthropods and plant pathogens
Mikrosistemske, nanosistemske tehnologije i komponente Innovative electronic components and systems based on inorganic and organic technologies embedded in consumer goods and products
“Modelling of the Pharmaceutical Spray Drying Process of the Emulsions in Laboratory and Pilot Scale” in collaboration with the industrial partner PLIVA Croatia Ltd. opical nanodelivery systems funded by the University of Zagreb (Z169)

Author's Bibliography

Investigation of morphology of the polyurethane/TiO2 composites

Stefanović, Ivan; Džunuzović, Jasna; Džunuzović, Enis; Ranđelović, Danijela; Basagni, Andrea; Marega, Carla

(Serbian Ceramic Society, 2024)

TY  - CONF
AU  - Stefanović, Ivan
AU  - Džunuzović, Jasna
AU  - Džunuzović, Enis
AU  - Ranđelović, Danijela
AU  - Basagni, Andrea
AU  - Marega, Carla
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7840
AB  - Two series of polyurethane (PU) composites based on poly(ε-caprolactone), aliphatic
hyperbranched polyester, isophorone diisocyanate and different content (0.5, 1 and 2 wt.%) of
unmodified or surface-modified TiO2 nanoparticles were prepared. For the surface modification
of TiO2 nanoparticles lauryl gallate was applied. Neat PU and composites were prepared by a
two-step solution polymerization method, using sonification in an ultrasonic bath for composite
fabrication in order to achieve homogenous distribution of nanoparticles, added in the first step of
polymerization reaction. Morphology of prepared neat PU and its composites were investigated
by utilizing scanning electron microscopy (SEM) and atomic force microscopy (AFM).
According to the obtained SEM micrographs, neat PU has compact and uniform cross-sectional
morphology, while in the structure of its composites small voids and certain micro-structures,
such as clusters or aggregates, can be observed. Furthermore, SEM-EDS measurements
confirmed the presence of Ti atoms in composites, originating from the incorporated nanoparticles. AFM analysis showed the existence of microphase separated morphology on the
surface of PU and its composites. Moreover, the surface of both series of composites became
rougher with the addition of nanoparticles, and its roughness increases with increasing amount of
TiO2 nanoparticles. Prepared PU composites may have potential application as coatings.
PB  - Serbian Ceramic Society
C3  - Conference Advanced Ceramics and Application : New Frontiers in Multifunctional Material Science and Processing, Program and the Book of abstracts; September 18-20, 2024; Belgrade, Serbia
T1  - Investigation of morphology of the polyurethane/TiO2 composites
SP  - 55
EP  - 56
UR  - https://hdl.handle.net/21.15107/rcub_cer_7840
ER  - 
@conference{
author = "Stefanović, Ivan and Džunuzović, Jasna and Džunuzović, Enis and Ranđelović, Danijela and Basagni, Andrea and Marega, Carla",
year = "2024",
abstract = "Two series of polyurethane (PU) composites based on poly(ε-caprolactone), aliphatic
hyperbranched polyester, isophorone diisocyanate and different content (0.5, 1 and 2 wt.%) of
unmodified or surface-modified TiO2 nanoparticles were prepared. For the surface modification
of TiO2 nanoparticles lauryl gallate was applied. Neat PU and composites were prepared by a
two-step solution polymerization method, using sonification in an ultrasonic bath for composite
fabrication in order to achieve homogenous distribution of nanoparticles, added in the first step of
polymerization reaction. Morphology of prepared neat PU and its composites were investigated
by utilizing scanning electron microscopy (SEM) and atomic force microscopy (AFM).
According to the obtained SEM micrographs, neat PU has compact and uniform cross-sectional
morphology, while in the structure of its composites small voids and certain micro-structures,
such as clusters or aggregates, can be observed. Furthermore, SEM-EDS measurements
confirmed the presence of Ti atoms in composites, originating from the incorporated nanoparticles. AFM analysis showed the existence of microphase separated morphology on the
surface of PU and its composites. Moreover, the surface of both series of composites became
rougher with the addition of nanoparticles, and its roughness increases with increasing amount of
TiO2 nanoparticles. Prepared PU composites may have potential application as coatings.",
publisher = "Serbian Ceramic Society",
journal = "Conference Advanced Ceramics and Application : New Frontiers in Multifunctional Material Science and Processing, Program and the Book of abstracts; September 18-20, 2024; Belgrade, Serbia",
title = "Investigation of morphology of the polyurethane/TiO2 composites",
pages = "55-56",
url = "https://hdl.handle.net/21.15107/rcub_cer_7840"
}
Stefanović, I., Džunuzović, J., Džunuzović, E., Ranđelović, D., Basagni, A.,& Marega, C.. (2024). Investigation of morphology of the polyurethane/TiO2 composites. in Conference Advanced Ceramics and Application : New Frontiers in Multifunctional Material Science and Processing, Program and the Book of abstracts; September 18-20, 2024; Belgrade, Serbia
Serbian Ceramic Society., 55-56.
https://hdl.handle.net/21.15107/rcub_cer_7840
Stefanović I, Džunuzović J, Džunuzović E, Ranđelović D, Basagni A, Marega C. Investigation of morphology of the polyurethane/TiO2 composites. in Conference Advanced Ceramics and Application : New Frontiers in Multifunctional Material Science and Processing, Program and the Book of abstracts; September 18-20, 2024; Belgrade, Serbia. 2024;:55-56.
https://hdl.handle.net/21.15107/rcub_cer_7840 .
Stefanović, Ivan, Džunuzović, Jasna, Džunuzović, Enis, Ranđelović, Danijela, Basagni, Andrea, Marega, Carla, "Investigation of morphology of the polyurethane/TiO2 composites" in Conference Advanced Ceramics and Application : New Frontiers in Multifunctional Material Science and Processing, Program and the Book of abstracts; September 18-20, 2024; Belgrade, Serbia (2024):55-56,
https://hdl.handle.net/21.15107/rcub_cer_7840 .

Morphology of the Polyurethane Networks Based on Polycaprolactone

Stefanović, Ivan; Džunuzović, Jasna; Džunuzović, Enis; Ranđelović, Danijela

(Serbian Academy of Sciences and Arts, 2024)

TY  - CONF
AU  - Stefanović, Ivan
AU  - Džunuzović, Jasna
AU  - Džunuzović, Enis
AU  - Ranđelović, Danijela
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7839
AB  - Polyurethane networks (PUNs) are versatile materials that have a wide range of
applications. Their structure is often segmented which means that it is built from thermodynamically incompatible flexible soft (SS) and rigid hard segments (HS) leading to the formation of microphase separation in the PUNs. With the careful design and selection of SS and HS it’s possible to control PUNs structure, morphology, solvent resistance, etc. Here, polycaprolactone (PCL) was used as SS to prepare segmented PUNs, due to its attractive features, such as low glass transition temperature (around -60 °C), biocompatibility, biodegradability, hydrophobicity, good solubility in various solvents, high permeability to many gasses, etc., in order to prepare PUNs with desired surface properties for their application as coatings [1,2].
In this study, a series of PUNs was synthesized by a two-step polymerization process, according to the procedure described elsewhere [1,3]. The synthesized PUNs are based on Boltorn®
hydroxy-functional aliphatic hyperbranched polyester of the second pseudo generation (BH-20,
Mn = 1340 g mol-1), isophorone diisocyanate (IPDI) and polycaprolactone diol (PCL, Mn
 = 2000 g mol-1). Five samples with diferent SS content (from 10 to 50 wt.% SS content) and constant –NCO/−OH molar ratio of 1.05 were synthesized. Stannous octoate (Sn(Oct)2
) was used as a catalyst, while a mixture of N,N-dimethylacetamide (DMAc) and tetrahydrofuran (THF) was used as a solvents during the synthesis of PUNs. PUN samples were labeled as PUN-XX, where XX represents the SS content (from 10 to 50). Surface morphology and the surface roughness of the PUNs were investigated by atomic force microscopy (AFM). AFM examination of
PUNs was performed by applying NTEGRA Prima atomic force microscope (NT-MDT, Moscow, Russia). Measurements were done using NT-MDT NSGO1 silicon cantilevers (N-type,
antimony doped with Au reflective coating). The nominal force constant of the cantilevers was
5.1 N m-1, whereas the cantilever driving frequency was around 150 kHz. Intermittent-contact
AFM mode was applied and data related with topography and phase were collected. AFM
images were created and analyzed with Image Analysis 2.2.0 (NT-MDT) and Gwyddion 2.61
(Free and Open Source software, Czech Metrology Institute) software. The scan area of the
PUNs surface was 20 × 20 μm2.
AFM analysis was carried out to explore the surface topography, homogeneity and the
impact of the SS content on microstructural features of the synthesized PUNs, such as nanometer scale structures and roughness. The recorded 3D height and 2D phase pictures (scan size 20
× 20 μm2) and obtained roughness values are presented in Figure 1 and Table 1, respectively.
According to the captured 3D height pictures it can be seen that surface topography of PUNs
strongly depends on the SS content. That is reflected in the fact that samples with smaller SS
content have more flat and smoother relief structures, without any larger domains, opposite
to the samples with the higher SS content. Furthermore, according to the presented 2D phase
pictures it can be observed that prepared PUNs have heterogeneous surface morphology, due to
the existence of more pronounced and more noticeable interface borders between phases. This
behavior is more prevalent in PUN samples with higher SS content [3]. The examined roughness of the PUNs shows that samples with SS content of 30 and 40 wt.% (PUN-30 and PUN-40
samples) have the highest roughness values (Rq and Ra, Table 1). The reason for this may lie in the fact that these samples have optimal ratio between HS and SS, allowing easier organization of SS [4].
A series of PUNs based on BH-20, IPDI and PCL was successfully synthesized. AFM
analysis showed that the content of SS has a significant impact on the surface properties of
these PUNs. Moreover, PUNs have two phase morphology that originates from the presence of
HS and SS, and it was more pronounced in the samples with higher SS content [5].
.
PB  - Serbian Academy of Sciences and Arts
C3  - Third International Conference On Electron Microscopy Of Nanostructures (ELMINA 2024), Program and Book of Abstracts; September 9-13, 2024, Belgrade, Serbia
T1  - Morphology of the Polyurethane Networks Based on Polycaprolactone
SP  - 150
EP  - 152
UR  - https://hdl.handle.net/21.15107/rcub_cer_7839
ER  - 
@conference{
author = "Stefanović, Ivan and Džunuzović, Jasna and Džunuzović, Enis and Ranđelović, Danijela",
year = "2024",
abstract = "Polyurethane networks (PUNs) are versatile materials that have a wide range of
applications. Their structure is often segmented which means that it is built from thermodynamically incompatible flexible soft (SS) and rigid hard segments (HS) leading to the formation of microphase separation in the PUNs. With the careful design and selection of SS and HS it’s possible to control PUNs structure, morphology, solvent resistance, etc. Here, polycaprolactone (PCL) was used as SS to prepare segmented PUNs, due to its attractive features, such as low glass transition temperature (around -60 °C), biocompatibility, biodegradability, hydrophobicity, good solubility in various solvents, high permeability to many gasses, etc., in order to prepare PUNs with desired surface properties for their application as coatings [1,2].
In this study, a series of PUNs was synthesized by a two-step polymerization process, according to the procedure described elsewhere [1,3]. The synthesized PUNs are based on Boltorn®
hydroxy-functional aliphatic hyperbranched polyester of the second pseudo generation (BH-20,
Mn = 1340 g mol-1), isophorone diisocyanate (IPDI) and polycaprolactone diol (PCL, Mn
 = 2000 g mol-1). Five samples with diferent SS content (from 10 to 50 wt.% SS content) and constant –NCO/−OH molar ratio of 1.05 were synthesized. Stannous octoate (Sn(Oct)2
) was used as a catalyst, while a mixture of N,N-dimethylacetamide (DMAc) and tetrahydrofuran (THF) was used as a solvents during the synthesis of PUNs. PUN samples were labeled as PUN-XX, where XX represents the SS content (from 10 to 50). Surface morphology and the surface roughness of the PUNs were investigated by atomic force microscopy (AFM). AFM examination of
PUNs was performed by applying NTEGRA Prima atomic force microscope (NT-MDT, Moscow, Russia). Measurements were done using NT-MDT NSGO1 silicon cantilevers (N-type,
antimony doped with Au reflective coating). The nominal force constant of the cantilevers was
5.1 N m-1, whereas the cantilever driving frequency was around 150 kHz. Intermittent-contact
AFM mode was applied and data related with topography and phase were collected. AFM
images were created and analyzed with Image Analysis 2.2.0 (NT-MDT) and Gwyddion 2.61
(Free and Open Source software, Czech Metrology Institute) software. The scan area of the
PUNs surface was 20 × 20 μm2.
AFM analysis was carried out to explore the surface topography, homogeneity and the
impact of the SS content on microstructural features of the synthesized PUNs, such as nanometer scale structures and roughness. The recorded 3D height and 2D phase pictures (scan size 20
× 20 μm2) and obtained roughness values are presented in Figure 1 and Table 1, respectively.
According to the captured 3D height pictures it can be seen that surface topography of PUNs
strongly depends on the SS content. That is reflected in the fact that samples with smaller SS
content have more flat and smoother relief structures, without any larger domains, opposite
to the samples with the higher SS content. Furthermore, according to the presented 2D phase
pictures it can be observed that prepared PUNs have heterogeneous surface morphology, due to
the existence of more pronounced and more noticeable interface borders between phases. This
behavior is more prevalent in PUN samples with higher SS content [3]. The examined roughness of the PUNs shows that samples with SS content of 30 and 40 wt.% (PUN-30 and PUN-40
samples) have the highest roughness values (Rq and Ra, Table 1). The reason for this may lie in the fact that these samples have optimal ratio between HS and SS, allowing easier organization of SS [4].
A series of PUNs based on BH-20, IPDI and PCL was successfully synthesized. AFM
analysis showed that the content of SS has a significant impact on the surface properties of
these PUNs. Moreover, PUNs have two phase morphology that originates from the presence of
HS and SS, and it was more pronounced in the samples with higher SS content [5].
.",
publisher = "Serbian Academy of Sciences and Arts",
journal = "Third International Conference On Electron Microscopy Of Nanostructures (ELMINA 2024), Program and Book of Abstracts; September 9-13, 2024, Belgrade, Serbia",
title = "Morphology of the Polyurethane Networks Based on Polycaprolactone",
pages = "150-152",
url = "https://hdl.handle.net/21.15107/rcub_cer_7839"
}
Stefanović, I., Džunuzović, J., Džunuzović, E.,& Ranđelović, D.. (2024). Morphology of the Polyurethane Networks Based on Polycaprolactone. in Third International Conference On Electron Microscopy Of Nanostructures (ELMINA 2024), Program and Book of Abstracts; September 9-13, 2024, Belgrade, Serbia
Serbian Academy of Sciences and Arts., 150-152.
https://hdl.handle.net/21.15107/rcub_cer_7839
Stefanović I, Džunuzović J, Džunuzović E, Ranđelović D. Morphology of the Polyurethane Networks Based on Polycaprolactone. in Third International Conference On Electron Microscopy Of Nanostructures (ELMINA 2024), Program and Book of Abstracts; September 9-13, 2024, Belgrade, Serbia. 2024;:150-152.
https://hdl.handle.net/21.15107/rcub_cer_7839 .
Stefanović, Ivan, Džunuzović, Jasna, Džunuzović, Enis, Ranđelović, Danijela, "Morphology of the Polyurethane Networks Based on Polycaprolactone" in Third International Conference On Electron Microscopy Of Nanostructures (ELMINA 2024), Program and Book of Abstracts; September 9-13, 2024, Belgrade, Serbia (2024):150-152,
https://hdl.handle.net/21.15107/rcub_cer_7839 .

Evaluation of PEGylation efficacy of curcumin-loaded nanoemulsions using complementary methods to assess protein interactions and physicochemical properties

Đoković, Jelena; Demisli, Sortiria; Savić, Sanela M.; Savić, Saša R.; Randjelović, Danijela; Marković, Bojan; Pantelić, Ivana; Mitrović, Jelena; Stanković, Tijana; Papadimitrou, Vassiliki; Xenakis, Aristotelis; Savić, Snežana

(Elsevier, 2024)

TY  - JOUR
AU  - Đoković, Jelena
AU  - Demisli, Sortiria
AU  - Savić, Sanela M.
AU  - Savić, Saša R.
AU  - Randjelović, Danijela
AU  - Marković, Bojan
AU  - Pantelić, Ivana
AU  - Mitrović, Jelena
AU  - Stanković, Tijana
AU  - Papadimitrou, Vassiliki
AU  - Xenakis, Aristotelis
AU  - Savić, Snežana
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7786
AB  - Nanoemulsions (NEs) are frequently used in the food, cosmetics and pharmaceutical industries to deliver nutraceuticals, pharmaceutical or cosmetic active ingredients. When administering NEs parenterally, various stabilisers are added to prevent rapid plasma clearance and to successfully deliver the active ingredient to the target site. For this purpose, PEGylation is often used to prolong the circulation time of the droplets. However, the problem is to determine the optimal concentration of the PEGylating agent – the PEGylation efficacy – that ensures adequate surface protection. This is a particular challenge when the active ingredient is incorporated into the stabilising layer, where any changes could disrupt the stability of the droplet. For this reason, we aimed to determine the optimal concentration of PEG2000-DSPE for surface protection of curcumin-loaded NEs for parenteral administration using electron paramagnetic resonance (EPR) spectroscopy. NEs were prepared using the high pressure homogenisation technique with 0.1 %, 0.3 % or 0.6 % of the PEGylated phospholipid. A droplet size of approximately 100 nm and polydispersity index below 0.25 indicated suitability for parenteral application. EPR analysis showed that PEG2000-DSPE had a stabilising effect on selected NEs, which was most pronounced in the part of the stabilising layer closest to the aqueous phase. To confirm these results, protein interaction studies were carried out using dynamic light scattering, UV–Vis spectroscopy, atomic force microscopy and release studies from protein-enriched media – bovine serum albumin (BSA) or foetal bovine serum (FBS) in phosphate-buffered saline. These analyses confirmed that the addition of PEG2000-DSPE reduced protein binding to the droplets as a function of concentration, with 0.3 % providing the best protection for the droplets. Our conclusions from the EPR spectroscopy study demonstrate the usefulness of EPR in determining the optimal concentrations of PEGylating agents for surface coverage and its usefulness in the formulation development phase.
PB  - Elsevier
T2  - Journal of Molecular Liquids
T1  - Evaluation of PEGylation efficacy of curcumin-loaded nanoemulsions using complementary methods to assess protein interactions and physicochemical properties
VL  - 404
SP  - 124888
DO  - 10.1016/j.molliq.2024.124888
ER  - 
@article{
author = "Đoković, Jelena and Demisli, Sortiria and Savić, Sanela M. and Savić, Saša R. and Randjelović, Danijela and Marković, Bojan and Pantelić, Ivana and Mitrović, Jelena and Stanković, Tijana and Papadimitrou, Vassiliki and Xenakis, Aristotelis and Savić, Snežana",
year = "2024",
abstract = "Nanoemulsions (NEs) are frequently used in the food, cosmetics and pharmaceutical industries to deliver nutraceuticals, pharmaceutical or cosmetic active ingredients. When administering NEs parenterally, various stabilisers are added to prevent rapid plasma clearance and to successfully deliver the active ingredient to the target site. For this purpose, PEGylation is often used to prolong the circulation time of the droplets. However, the problem is to determine the optimal concentration of the PEGylating agent – the PEGylation efficacy – that ensures adequate surface protection. This is a particular challenge when the active ingredient is incorporated into the stabilising layer, where any changes could disrupt the stability of the droplet. For this reason, we aimed to determine the optimal concentration of PEG2000-DSPE for surface protection of curcumin-loaded NEs for parenteral administration using electron paramagnetic resonance (EPR) spectroscopy. NEs were prepared using the high pressure homogenisation technique with 0.1 %, 0.3 % or 0.6 % of the PEGylated phospholipid. A droplet size of approximately 100 nm and polydispersity index below 0.25 indicated suitability for parenteral application. EPR analysis showed that PEG2000-DSPE had a stabilising effect on selected NEs, which was most pronounced in the part of the stabilising layer closest to the aqueous phase. To confirm these results, protein interaction studies were carried out using dynamic light scattering, UV–Vis spectroscopy, atomic force microscopy and release studies from protein-enriched media – bovine serum albumin (BSA) or foetal bovine serum (FBS) in phosphate-buffered saline. These analyses confirmed that the addition of PEG2000-DSPE reduced protein binding to the droplets as a function of concentration, with 0.3 % providing the best protection for the droplets. Our conclusions from the EPR spectroscopy study demonstrate the usefulness of EPR in determining the optimal concentrations of PEGylating agents for surface coverage and its usefulness in the formulation development phase.",
publisher = "Elsevier",
journal = "Journal of Molecular Liquids",
title = "Evaluation of PEGylation efficacy of curcumin-loaded nanoemulsions using complementary methods to assess protein interactions and physicochemical properties",
volume = "404",
pages = "124888",
doi = "10.1016/j.molliq.2024.124888"
}
Đoković, J., Demisli, S., Savić, S. M., Savić, S. R., Randjelović, D., Marković, B., Pantelić, I., Mitrović, J., Stanković, T., Papadimitrou, V., Xenakis, A.,& Savić, S.. (2024). Evaluation of PEGylation efficacy of curcumin-loaded nanoemulsions using complementary methods to assess protein interactions and physicochemical properties. in Journal of Molecular Liquids
Elsevier., 404, 124888.
https://doi.org/10.1016/j.molliq.2024.124888
Đoković J, Demisli S, Savić SM, Savić SR, Randjelović D, Marković B, Pantelić I, Mitrović J, Stanković T, Papadimitrou V, Xenakis A, Savić S. Evaluation of PEGylation efficacy of curcumin-loaded nanoemulsions using complementary methods to assess protein interactions and physicochemical properties. in Journal of Molecular Liquids. 2024;404:124888.
doi:10.1016/j.molliq.2024.124888 .
Đoković, Jelena, Demisli, Sortiria, Savić, Sanela M., Savić, Saša R., Randjelović, Danijela, Marković, Bojan, Pantelić, Ivana, Mitrović, Jelena, Stanković, Tijana, Papadimitrou, Vassiliki, Xenakis, Aristotelis, Savić, Snežana, "Evaluation of PEGylation efficacy of curcumin-loaded nanoemulsions using complementary methods to assess protein interactions and physicochemical properties" in Journal of Molecular Liquids, 404 (2024):124888,
https://doi.org/10.1016/j.molliq.2024.124888 . .

Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration

Joksimović, Kristina; Lješević, Marija; Lončarević, Branka; Žerađanin, Aleksandra; Kodranov, Igor; Randjelović, Danijela; Beškoski, Vladimir

(Chemical Society of Montenegro, 2023)

TY  - CONF
AU  - Joksimović, Kristina
AU  - Lješević, Marija
AU  - Lončarević, Branka
AU  - Žerađanin, Aleksandra
AU  - Kodranov, Igor
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7121
AB  - Microbial fuel cells (MFCs) are a promising technology that has the potential to solve environmental problems while simultaneously generating electricity. Thanks to the direct use of energy from the substrate and its conversion into electricity, as well as the controlled production of activated sludge, the multiplicity of independent applications highly qualifies MFC for the use of wastewater treatment. Wastewater from various industries is an ideal source of organic substrate that can potentially be used in MFC systems. In this way besides degrading organic pollutants, generated energy can be obtained as added value and used for various purposes.
PB  - Chemical Society of Montenegro
C3  - 23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro
T1  - Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration
SP  - 96
EP  - 96
UR  - https://hdl.handle.net/21.15107/rcub_cer_7121
ER  - 
@conference{
author = "Joksimović, Kristina and Lješević, Marija and Lončarević, Branka and Žerađanin, Aleksandra and Kodranov, Igor and Randjelović, Danijela and Beškoski, Vladimir",
year = "2023",
abstract = "Microbial fuel cells (MFCs) are a promising technology that has the potential to solve environmental problems while simultaneously generating electricity. Thanks to the direct use of energy from the substrate and its conversion into electricity, as well as the controlled production of activated sludge, the multiplicity of independent applications highly qualifies MFC for the use of wastewater treatment. Wastewater from various industries is an ideal source of organic substrate that can potentially be used in MFC systems. In this way besides degrading organic pollutants, generated energy can be obtained as added value and used for various purposes.",
publisher = "Chemical Society of Montenegro",
journal = "23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro",
title = "Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration",
pages = "96-96",
url = "https://hdl.handle.net/21.15107/rcub_cer_7121"
}
Joksimović, K., Lješević, M., Lončarević, B., Žerađanin, A., Kodranov, I., Randjelović, D.,& Beškoski, V.. (2023). Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration. in 23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro
Chemical Society of Montenegro., 96-96.
https://hdl.handle.net/21.15107/rcub_cer_7121
Joksimović K, Lješević M, Lončarević B, Žerađanin A, Kodranov I, Randjelović D, Beškoski V. Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration. in 23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro. 2023;:96-96.
https://hdl.handle.net/21.15107/rcub_cer_7121 .
Joksimović, Kristina, Lješević, Marija, Lončarević, Branka, Žerađanin, Aleksandra, Kodranov, Igor, Randjelović, Danijela, Beškoski, Vladimir, "Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration" in 23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro (2023):96-96,
https://hdl.handle.net/21.15107/rcub_cer_7121 .

Utilization of carbon fiber in the context of microbial fuel cell systems

Joksimović, Kristina; Žerađanin, Aleksandra; Lončarević, Branka; Lješević, Marija; Randjelović, Danijela; Beškoski, Vladimir

(Institute of Technical Sciences of SASA, 2023)

TY  - CONF
AU  - Joksimović, Kristina
AU  - Žerađanin, Aleksandra
AU  - Lončarević, Branka
AU  - Lješević, Marija
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7117
AB  - The paramount challenge of the 21st century lies in the profound energy demands imposed by
contemporary society. The utilization of energy derived from non-renewable sources,
notably coal, oil, and their byproducts, is intrinsically associated with grave environmental
repercussions, primarily manifested in the form of pollution. The notion of fuel cells stands
as a prospective resolution to this problem, offering a sustainable avenue for energy
production devoid of environmentally adverse emissions. The aim of this research was to
explore the potential of carbon cloth electrodes in the Microbial Fuel Cell (MFC) system.
PB  - Institute of Technical Sciences of SASA
C3  - Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade
T1  - Utilization of carbon fiber in the context of microbial fuel cell systems
SP  - 70
EP  - 70
UR  - https://hdl.handle.net/21.15107/rcub_cer_7117
ER  - 
@conference{
author = "Joksimović, Kristina and Žerađanin, Aleksandra and Lončarević, Branka and Lješević, Marija and Randjelović, Danijela and Beškoski, Vladimir",
year = "2023",
abstract = "The paramount challenge of the 21st century lies in the profound energy demands imposed by
contemporary society. The utilization of energy derived from non-renewable sources,
notably coal, oil, and their byproducts, is intrinsically associated with grave environmental
repercussions, primarily manifested in the form of pollution. The notion of fuel cells stands
as a prospective resolution to this problem, offering a sustainable avenue for energy
production devoid of environmentally adverse emissions. The aim of this research was to
explore the potential of carbon cloth electrodes in the Microbial Fuel Cell (MFC) system.",
publisher = "Institute of Technical Sciences of SASA",
journal = "Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade",
title = "Utilization of carbon fiber in the context of microbial fuel cell systems",
pages = "70-70",
url = "https://hdl.handle.net/21.15107/rcub_cer_7117"
}
Joksimović, K., Žerađanin, A., Lončarević, B., Lješević, M., Randjelović, D.,& Beškoski, V.. (2023). Utilization of carbon fiber in the context of microbial fuel cell systems. in Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade
Institute of Technical Sciences of SASA., 70-70.
https://hdl.handle.net/21.15107/rcub_cer_7117
Joksimović K, Žerađanin A, Lončarević B, Lješević M, Randjelović D, Beškoski V. Utilization of carbon fiber in the context of microbial fuel cell systems. in Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade. 2023;:70-70.
https://hdl.handle.net/21.15107/rcub_cer_7117 .
Joksimović, Kristina, Žerađanin, Aleksandra, Lončarević, Branka, Lješević, Marija, Randjelović, Danijela, Beškoski, Vladimir, "Utilization of carbon fiber in the context of microbial fuel cell systems" in Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade (2023):70-70,
https://hdl.handle.net/21.15107/rcub_cer_7117 .

High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances

Mitrović, Jelena; Divović-Matović, Branka; Knutson, Daniel E.; Petković, Miloš; Đorović, Đordje; Randjelović, Danijela; Dobričić, Vladimir D.; Đoković, Jelena B.; Lunter, Dominique J.; Cook, James M.; Savić, Miroslav M.; Savić, Snežana D.

(Elsevier B.V., 2023)

TY  - JOUR
AU  - Mitrović, Jelena
AU  - Divović-Matović, Branka
AU  - Knutson, Daniel E.
AU  - Petković, Miloš
AU  - Đorović, Đordje
AU  - Randjelović, Danijela
AU  - Dobričić, Vladimir D.
AU  - Đoković, Jelena B.
AU  - Lunter, Dominique J.
AU  - Cook, James M.
AU  - Savić, Miroslav M.
AU  - Savić, Snežana D.
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5665
AB  - Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in water and oils. DK-I-60-3 (7-methoxy-d3-2-(4-methoxy-d3-phenyl)-2,5-dihydro-3Hpyrazolo[4,3-c]quinolin-3-one) is one of such pyrazoloquinolinones, and we recently reported about increased oral bioavailability of its nanocrystal formulation (NC). Lipid nanoparticles (LNP) with a high concentration of lecithin, which enhances loading capacity of the lipid matrix, may give rise to further improvement. After preformulation studies by differential scanning calorimetry and polarized light microscopy, LNP were prepared by the hot high pressure homogenization, and characterized in terms of particle size, morphology, and encapsulation efficacy. The layered structure visible on atomic force micrographs was confirmed by nuclear magnetic resonance. Obtained formulations were desirably stable, with small particle size (<100 nm), and high encapsulation efficacy (>99 %). Lecithin was partially fluid and most probably located in the outer shell of the particle, together with DK-I-60-3. While the hydrophobic part of polysorbate 80 was completely immobilized, its hydrophilic part was free in the aqueous phase. In oral neuropharmacokinetic study in rats, an around 1.5-fold increase of area under the curve with LNP compared to NC was noticed both in brain and plasma. In bioavailability study, F value of LNP (34.7 ± 12.4 %) was 1.4-fold higher than of NC (24.5 ± 7.8 %); however, this difference did not reach statistical significance. Therefore, employment of LNP platform in preclinical formulation of DK-I-60-3 imparted an incremental improvement of its physicochemical as well as pharmacokinetic behavior.
PB  - Elsevier B.V.
T2  - International Journal of Pharmaceutics
T1  - High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances
VL  - 633
SP  - 122613
DO  - 10.1016/j.ijpharm.2023.122613
ER  - 
@article{
author = "Mitrović, Jelena and Divović-Matović, Branka and Knutson, Daniel E. and Petković, Miloš and Đorović, Đordje and Randjelović, Danijela and Dobričić, Vladimir D. and Đoković, Jelena B. and Lunter, Dominique J. and Cook, James M. and Savić, Miroslav M. and Savić, Snežana D.",
year = "2023",
abstract = "Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in water and oils. DK-I-60-3 (7-methoxy-d3-2-(4-methoxy-d3-phenyl)-2,5-dihydro-3Hpyrazolo[4,3-c]quinolin-3-one) is one of such pyrazoloquinolinones, and we recently reported about increased oral bioavailability of its nanocrystal formulation (NC). Lipid nanoparticles (LNP) with a high concentration of lecithin, which enhances loading capacity of the lipid matrix, may give rise to further improvement. After preformulation studies by differential scanning calorimetry and polarized light microscopy, LNP were prepared by the hot high pressure homogenization, and characterized in terms of particle size, morphology, and encapsulation efficacy. The layered structure visible on atomic force micrographs was confirmed by nuclear magnetic resonance. Obtained formulations were desirably stable, with small particle size (<100 nm), and high encapsulation efficacy (>99 %). Lecithin was partially fluid and most probably located in the outer shell of the particle, together with DK-I-60-3. While the hydrophobic part of polysorbate 80 was completely immobilized, its hydrophilic part was free in the aqueous phase. In oral neuropharmacokinetic study in rats, an around 1.5-fold increase of area under the curve with LNP compared to NC was noticed both in brain and plasma. In bioavailability study, F value of LNP (34.7 ± 12.4 %) was 1.4-fold higher than of NC (24.5 ± 7.8 %); however, this difference did not reach statistical significance. Therefore, employment of LNP platform in preclinical formulation of DK-I-60-3 imparted an incremental improvement of its physicochemical as well as pharmacokinetic behavior.",
publisher = "Elsevier B.V.",
journal = "International Journal of Pharmaceutics",
title = "High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances",
volume = "633",
pages = "122613",
doi = "10.1016/j.ijpharm.2023.122613"
}
Mitrović, J., Divović-Matović, B., Knutson, D. E., Petković, M., Đorović, Đ., Randjelović, D., Dobričić, V. D., Đoković, J. B., Lunter, D. J., Cook, J. M., Savić, M. M.,& Savić, S. D.. (2023). High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances. in International Journal of Pharmaceutics
Elsevier B.V.., 633, 122613.
https://doi.org/10.1016/j.ijpharm.2023.122613
Mitrović J, Divović-Matović B, Knutson DE, Petković M, Đorović Đ, Randjelović D, Dobričić VD, Đoković JB, Lunter DJ, Cook JM, Savić MM, Savić SD. High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances. in International Journal of Pharmaceutics. 2023;633:122613.
doi:10.1016/j.ijpharm.2023.122613 .
Mitrović, Jelena, Divović-Matović, Branka, Knutson, Daniel E., Petković, Miloš, Đorović, Đordje, Randjelović, Danijela, Dobričić, Vladimir D., Đoković, Jelena B., Lunter, Dominique J., Cook, James M., Savić, Miroslav M., Savić, Snežana D., "High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances" in International Journal of Pharmaceutics, 633 (2023):122613,
https://doi.org/10.1016/j.ijpharm.2023.122613 . .
5
3
4

Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta

Lončarević, Branka; Joksimović, Kristina; Popović, Lazar; Avdalović, Jelena; Randjelović, Danijela; Beškoski, Vladimir

(Srpsko hemijsko društvo, 2023)

TY  - CONF
AU  - Lončarević, Branka
AU  - Joksimović, Kristina
AU  - Popović, Lazar
AU  - Avdalović, Jelena
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6427
AB  - Aktivnost mikroorganizama je direktno povezana sa njihovim disanjem. U prisustvu
velikih količina biodostupne organske supstance, brzina disanja mikroorganizama je veća.
Praćenje disanja je postalo bitan parametar u raznim procesima biodegradacije otpadne
supstance. Stoga, cilj ovog rada obuhvata praćenje ćelijskog disanja pomoću Micro-Oxymax
respirometra, kako bi se dobio bolji uvid u prisustvo dostupne organske supstance u
upotrebljenom rečnom sedimentu za generisanje električne energije pomoću MFC
PB  - Srpsko hemijsko društvo
C3  - Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023
T1  - Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta
T1  - Respiration of microorganisms in the MFC system during the generation of energy from river sediment
SP  - 169
EP  - 170
UR  - https://hdl.handle.net/21.15107/rcub_cer_6427
ER  - 
@conference{
author = "Lončarević, Branka and Joksimović, Kristina and Popović, Lazar and Avdalović, Jelena and Randjelović, Danijela and Beškoski, Vladimir",
year = "2023",
abstract = "Aktivnost mikroorganizama je direktno povezana sa njihovim disanjem. U prisustvu
velikih količina biodostupne organske supstance, brzina disanja mikroorganizama je veća.
Praćenje disanja je postalo bitan parametar u raznim procesima biodegradacije otpadne
supstance. Stoga, cilj ovog rada obuhvata praćenje ćelijskog disanja pomoću Micro-Oxymax
respirometra, kako bi se dobio bolji uvid u prisustvo dostupne organske supstance u
upotrebljenom rečnom sedimentu za generisanje električne energije pomoću MFC",
publisher = "Srpsko hemijsko društvo",
journal = "Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023",
title = "Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta, Respiration of microorganisms in the MFC system during the generation of energy from river sediment",
pages = "169-170",
url = "https://hdl.handle.net/21.15107/rcub_cer_6427"
}
Lončarević, B., Joksimović, K., Popović, L., Avdalović, J., Randjelović, D.,& Beškoski, V.. (2023). Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta. in Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023
Srpsko hemijsko društvo., 169-170.
https://hdl.handle.net/21.15107/rcub_cer_6427
Lončarević B, Joksimović K, Popović L, Avdalović J, Randjelović D, Beškoski V. Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta. in Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023. 2023;:169-170.
https://hdl.handle.net/21.15107/rcub_cer_6427 .
Lončarević, Branka, Joksimović, Kristina, Popović, Lazar, Avdalović, Jelena, Randjelović, Danijela, Beškoski, Vladimir, "Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta" in Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023 (2023):169-170,
https://hdl.handle.net/21.15107/rcub_cer_6427 .

Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography

Kašiković, Nemanja; Jurič, Ivana; Randjelović, Danijela; Spiridonov, Iskren; Żołek-Tryznowska, Zuzanna; Boeva, Rumyana; Petrović, Saša

(Osijek : Sveučilište Josipa Jurja Strossmayera, 2023)

TY  - JOUR
AU  - Kašiković, Nemanja
AU  - Jurič, Ivana
AU  - Randjelović, Danijela
AU  - Spiridonov, Iskren
AU  - Żołek-Tryznowska, Zuzanna
AU  - Boeva, Rumyana
AU  - Petrović, Saša
PY  - 2023
UR  - https://hrcak.srce.hr/file/426027
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5868
AB  - Electrophotography is affected by several parameters, including printing machines and paper type, which determine the final quality of reproduction. For the
investigation of those effects, tests were done on the three types of electrophotography printing machines and eight types of uncoated paper with different properties of
weight, surface roughness, whiteness, brightness and opacity. Samples were printed with cyan, magenta, yellow and black toner under the standard, identical conditions.
The assessment of standard print quality parameter (optical density) was done using spectrodensitometer Techkon Spectro Dens. At the same time, the paper substrates
were characterized using the atomic force microscopy (AFM) as well as by spectrophotometric measurements (X Rite Eye-One, i1). Obtained results showed that the
reproducibility significantly depends on the type of printing machine rather than optical and mechanical properties of paper.
PB  - Osijek : Sveučilište Josipa Jurja Strossmayera
PB  - Slavonski brod : Strojarski Fakultet
T2  - Technical Gazette (Tehnički vjesnik)
T1  - Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography
VL  - 30
IS  - 2
SP  - 481
EP  - 485
DO  - 10.17559/TV-20220725151112
ER  - 
@article{
author = "Kašiković, Nemanja and Jurič, Ivana and Randjelović, Danijela and Spiridonov, Iskren and Żołek-Tryznowska, Zuzanna and Boeva, Rumyana and Petrović, Saša",
year = "2023",
abstract = "Electrophotography is affected by several parameters, including printing machines and paper type, which determine the final quality of reproduction. For the
investigation of those effects, tests were done on the three types of electrophotography printing machines and eight types of uncoated paper with different properties of
weight, surface roughness, whiteness, brightness and opacity. Samples were printed with cyan, magenta, yellow and black toner under the standard, identical conditions.
The assessment of standard print quality parameter (optical density) was done using spectrodensitometer Techkon Spectro Dens. At the same time, the paper substrates
were characterized using the atomic force microscopy (AFM) as well as by spectrophotometric measurements (X Rite Eye-One, i1). Obtained results showed that the
reproducibility significantly depends on the type of printing machine rather than optical and mechanical properties of paper.",
publisher = "Osijek : Sveučilište Josipa Jurja Strossmayera, Slavonski brod : Strojarski Fakultet",
journal = "Technical Gazette (Tehnički vjesnik)",
title = "Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography",
volume = "30",
number = "2",
pages = "481-485",
doi = "10.17559/TV-20220725151112"
}
Kašiković, N., Jurič, I., Randjelović, D., Spiridonov, I., Żołek-Tryznowska, Z., Boeva, R.,& Petrović, S.. (2023). Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography. in Technical Gazette (Tehnički vjesnik)
Osijek : Sveučilište Josipa Jurja Strossmayera., 30(2), 481-485.
https://doi.org/10.17559/TV-20220725151112
Kašiković N, Jurič I, Randjelović D, Spiridonov I, Żołek-Tryznowska Z, Boeva R, Petrović S. Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography. in Technical Gazette (Tehnički vjesnik). 2023;30(2):481-485.
doi:10.17559/TV-20220725151112 .
Kašiković, Nemanja, Jurič, Ivana, Randjelović, Danijela, Spiridonov, Iskren, Żołek-Tryznowska, Zuzanna, Boeva, Rumyana, Petrović, Saša, "Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography" in Technical Gazette (Tehnički vjesnik), 30, no. 2 (2023):481-485,
https://doi.org/10.17559/TV-20220725151112 . .

Sizing experiments and bio-nano interactions: method matters

Nikolić, Ines; Petrović, Marija; Krupnik, Leondard; Randjelović, Danijela; Avaro, Jonathan; Neels, Antonia; Borchard, Gerrit; Jordan, Olivier; Đoković, Jelena; Savić, Snežana

(2023)

TY  - CONF
AU  - Nikolić, Ines
AU  - Petrović, Marija
AU  - Krupnik, Leondard
AU  - Randjelović, Danijela
AU  - Avaro, Jonathan
AU  - Neels, Antonia
AU  - Borchard, Gerrit
AU  - Jordan, Olivier
AU  - Đoković, Jelena
AU  - Savić, Snežana
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6419
AB  - The aim of the presented research was to perform a thorough analysis of the selected nanosystem (nanoemulsion) focusing on size estimation and particle-protein interaction applying several state-of-the art techniques, highlighting important factors for a reliable analysis.
T1  - Sizing experiments and bio-nano interactions: method matters
UR  - https://hdl.handle.net/21.15107/rcub_cer_6419
ER  - 
@conference{
author = "Nikolić, Ines and Petrović, Marija and Krupnik, Leondard and Randjelović, Danijela and Avaro, Jonathan and Neels, Antonia and Borchard, Gerrit and Jordan, Olivier and Đoković, Jelena and Savić, Snežana",
year = "2023",
abstract = "The aim of the presented research was to perform a thorough analysis of the selected nanosystem (nanoemulsion) focusing on size estimation and particle-protein interaction applying several state-of-the art techniques, highlighting important factors for a reliable analysis.",
title = "Sizing experiments and bio-nano interactions: method matters",
url = "https://hdl.handle.net/21.15107/rcub_cer_6419"
}
Nikolić, I., Petrović, M., Krupnik, L., Randjelović, D., Avaro, J., Neels, A., Borchard, G., Jordan, O., Đoković, J.,& Savić, S.. (2023). Sizing experiments and bio-nano interactions: method matters. .
https://hdl.handle.net/21.15107/rcub_cer_6419
Nikolić I, Petrović M, Krupnik L, Randjelović D, Avaro J, Neels A, Borchard G, Jordan O, Đoković J, Savić S. Sizing experiments and bio-nano interactions: method matters. 2023;.
https://hdl.handle.net/21.15107/rcub_cer_6419 .
Nikolić, Ines, Petrović, Marija, Krupnik, Leondard, Randjelović, Danijela, Avaro, Jonathan, Neels, Antonia, Borchard, Gerrit, Jordan, Olivier, Đoković, Jelena, Savić, Snežana, "Sizing experiments and bio-nano interactions: method matters" (2023),
https://hdl.handle.net/21.15107/rcub_cer_6419 .

Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer

Bulatović, Sandra; Marković, Bojana; Tadić, Tamara; Nastasović, Aleksandra; Ilić, Mila; Randjelović, Danijela; Nedić, Natalija

(Skopje : Society of chemists and technologists of Macedonia, 2023)

TY  - CONF
AU  - Bulatović, Sandra
AU  - Marković, Bojana
AU  - Tadić, Tamara
AU  - Nastasović, Aleksandra
AU  - Ilić, Mila
AU  - Randjelović, Danijela
AU  - Nedić, Natalija
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6692
AB  - Macroporous (glycidyl methacrylate) GMA-based composite was
synthesized via suspension polymerization in the presence of 2 wt. % magnetic
nanoparticles and functionalized with triethylenetetramine. Copper was immobilized
on composite by contacting modified copolymer with 0.1 M solution of CuCl2, at pH
5, and 25 ̊C. The obtained composite was characterized by mercury porosimetry,
Fourier transform infrared spectroscopy (FTIR) analysis and atomic force
microscopy (AFM). GMA-based composites, due to their properties (size, porosity,
etc.), and the presence of reactive epoxy group, have found a variety of applications
as sorbents, enzyme supports, in biomedical applications, for metal and organic
compounds sorption.1
The antimicrobial activity of the synthesized GMA/Cu copolymer against
Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger as
representatives for Gram-positive bacteria, Gram-negative bacteria, yeast and fungi
were investigated in this study.2 The copolymer displayed good antimicrobial activity
against all analyzed microbes, which makes it a material that can be potentially used
for biomedical (antibacterial and antifungal) applications.
PB  - Skopje : Society of chemists and technologists of Macedonia
C3  - Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia
T1  - Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer
SP  - 163
EP  - 163
UR  - https://hdl.handle.net/21.15107/rcub_cer_6692
ER  - 
@conference{
author = "Bulatović, Sandra and Marković, Bojana and Tadić, Tamara and Nastasović, Aleksandra and Ilić, Mila and Randjelović, Danijela and Nedić, Natalija",
year = "2023",
abstract = "Macroporous (glycidyl methacrylate) GMA-based composite was
synthesized via suspension polymerization in the presence of 2 wt. % magnetic
nanoparticles and functionalized with triethylenetetramine. Copper was immobilized
on composite by contacting modified copolymer with 0.1 M solution of CuCl2, at pH
5, and 25 ̊C. The obtained composite was characterized by mercury porosimetry,
Fourier transform infrared spectroscopy (FTIR) analysis and atomic force
microscopy (AFM). GMA-based composites, due to their properties (size, porosity,
etc.), and the presence of reactive epoxy group, have found a variety of applications
as sorbents, enzyme supports, in biomedical applications, for metal and organic
compounds sorption.1
The antimicrobial activity of the synthesized GMA/Cu copolymer against
Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger as
representatives for Gram-positive bacteria, Gram-negative bacteria, yeast and fungi
were investigated in this study.2 The copolymer displayed good antimicrobial activity
against all analyzed microbes, which makes it a material that can be potentially used
for biomedical (antibacterial and antifungal) applications.",
publisher = "Skopje : Society of chemists and technologists of Macedonia",
journal = "Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia",
title = "Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer",
pages = "163-163",
url = "https://hdl.handle.net/21.15107/rcub_cer_6692"
}
Bulatović, S., Marković, B., Tadić, T., Nastasović, A., Ilić, M., Randjelović, D.,& Nedić, N.. (2023). Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer. in Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia
Skopje : Society of chemists and technologists of Macedonia., 163-163.
https://hdl.handle.net/21.15107/rcub_cer_6692
Bulatović S, Marković B, Tadić T, Nastasović A, Ilić M, Randjelović D, Nedić N. Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer. in Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia. 2023;:163-163.
https://hdl.handle.net/21.15107/rcub_cer_6692 .
Bulatović, Sandra, Marković, Bojana, Tadić, Tamara, Nastasović, Aleksandra, Ilić, Mila, Randjelović, Danijela, Nedić, Natalija, "Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer" in Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia (2023):163-163,
https://hdl.handle.net/21.15107/rcub_cer_6692 .

The influence of polycaprolactone content on the surface properties of polyurethane networks

Stefanović, Ivan; Džunuzović, Jasna; Džunuzović, Enis; Randjelović, Danijela

(John Wiley and Sons Inc., 2023)

TY  - JOUR
AU  - Stefanović, Ivan
AU  - Džunuzović, Jasna
AU  - Džunuzović, Enis
AU  - Randjelović, Danijela
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7192
AB  - The aim of this work was to examine the influence of polycaprolactone (PCL) as a soft segment (SS) on the surface properties of polyurethane networks (PUNs). Five PUNs with different SS content (from 10 to 50 wt%) were prepared using Boltorn® aliphatic hyperbranched polyester of the second pseudo generation and isophorone diisocyanate as components of hard segments. The structure, hydrophobicity, wettability, and swelling behavior of these PUNs were investigated. Primarily, the obtained results showed that properties of prepared PUNs strongly depend on the content of SS that is, PCL. It has been established that the increase of SS content reduced the degree of hydrogen bonding in PUNs. Also, the increase of the SS content in PUNs induced appearance of more pronounced microphase separated morphology, better hydrophobicity and non-wetting with diiodomethane. Simultaneously, the increase of the SS content led to the decrease of contact angles with formamide, and surface free energy of the prepared PUNs. These PUNs show good surface properties that are required for their potential application such as coatings.
PB  - John Wiley and Sons Inc.
T2  - Journal of Applied Polymer Science
T1  - The influence of polycaprolactone content on the surface properties of polyurethane networks
SP  - e54989
DO  - 10.1002/app.54989
ER  - 
@article{
author = "Stefanović, Ivan and Džunuzović, Jasna and Džunuzović, Enis and Randjelović, Danijela",
year = "2023",
abstract = "The aim of this work was to examine the influence of polycaprolactone (PCL) as a soft segment (SS) on the surface properties of polyurethane networks (PUNs). Five PUNs with different SS content (from 10 to 50 wt%) were prepared using Boltorn® aliphatic hyperbranched polyester of the second pseudo generation and isophorone diisocyanate as components of hard segments. The structure, hydrophobicity, wettability, and swelling behavior of these PUNs were investigated. Primarily, the obtained results showed that properties of prepared PUNs strongly depend on the content of SS that is, PCL. It has been established that the increase of SS content reduced the degree of hydrogen bonding in PUNs. Also, the increase of the SS content in PUNs induced appearance of more pronounced microphase separated morphology, better hydrophobicity and non-wetting with diiodomethane. Simultaneously, the increase of the SS content led to the decrease of contact angles with formamide, and surface free energy of the prepared PUNs. These PUNs show good surface properties that are required for their potential application such as coatings.",
publisher = "John Wiley and Sons Inc.",
journal = "Journal of Applied Polymer Science",
title = "The influence of polycaprolactone content on the surface properties of polyurethane networks",
pages = "e54989",
doi = "10.1002/app.54989"
}
Stefanović, I., Džunuzović, J., Džunuzović, E.,& Randjelović, D.. (2023). The influence of polycaprolactone content on the surface properties of polyurethane networks. in Journal of Applied Polymer Science
John Wiley and Sons Inc.., e54989.
https://doi.org/10.1002/app.54989
Stefanović I, Džunuzović J, Džunuzović E, Randjelović D. The influence of polycaprolactone content on the surface properties of polyurethane networks. in Journal of Applied Polymer Science. 2023;:e54989.
doi:10.1002/app.54989 .
Stefanović, Ivan, Džunuzović, Jasna, Džunuzović, Enis, Randjelović, Danijela, "The influence of polycaprolactone content on the surface properties of polyurethane networks" in Journal of Applied Polymer Science (2023):e54989,
https://doi.org/10.1002/app.54989 . .

Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study

Timotijević, Mirjana; Ilić, Tanja; Marković, Bojan; Randjelović, Danijela; Cekić, Nebojša; Nikolić, Ines; Savić, Snežana; Pantelić, Ivana

(MDPI, 2022)

TY  - JOUR
AU  - Timotijević, Mirjana
AU  - Ilić, Tanja
AU  - Marković, Bojan
AU  - Randjelović, Danijela
AU  - Cekić, Nebojša
AU  - Nikolić, Ines
AU  - Savić, Snežana
AU  - Pantelić, Ivana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5258
AB  - Polymeric film-forming systems have emerged as an esthetically acceptable option for targeted, less frequent and controlled dermal drug delivery. However, their dynamic nature (rapid evaporation of solvents leading to the formation of thin films) presents a true characterization chal- lenge. In this study, we tested a tiered characterization approach, leading to more efficient definition of the quality target product profiles of film-forming systems. After assessing a number of physico- chemico-mechanical properties, thermal, spectroscopic and microscopic techniques were introduced. Final confirmation of betamethasone dipropionate-loaded FFS biopharmaceutical properties was sought via an in vitro skin permeation study. A number of applied characterization methods showed complementarity. The sample based on a combination of hydrophobic Eudragit® RS PO and hy- droxypropyl cellulose showed higher viscosity (47.17 ± 3.06 mPa·s) and film thickness, resulting in sustained skin permeation (permeation rate of 0.348 ± 0.157 ng/cm2 h), and even the pH of the sample with Eudragit® NE 30D, along with higher surface roughness and thermal analysis, implied its immediate delivery through the epidermal membrane. Therefore, this study revealed the utility of several methods able to refine the number of needed tests within the final product profile.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study
VL  - 23
IS  - 11
DO  - 10.3390/ijms23116013
ER  - 
@article{
author = "Timotijević, Mirjana and Ilić, Tanja and Marković, Bojan and Randjelović, Danijela and Cekić, Nebojša and Nikolić, Ines and Savić, Snežana and Pantelić, Ivana",
year = "2022",
abstract = "Polymeric film-forming systems have emerged as an esthetically acceptable option for targeted, less frequent and controlled dermal drug delivery. However, their dynamic nature (rapid evaporation of solvents leading to the formation of thin films) presents a true characterization chal- lenge. In this study, we tested a tiered characterization approach, leading to more efficient definition of the quality target product profiles of film-forming systems. After assessing a number of physico- chemico-mechanical properties, thermal, spectroscopic and microscopic techniques were introduced. Final confirmation of betamethasone dipropionate-loaded FFS biopharmaceutical properties was sought via an in vitro skin permeation study. A number of applied characterization methods showed complementarity. The sample based on a combination of hydrophobic Eudragit® RS PO and hy- droxypropyl cellulose showed higher viscosity (47.17 ± 3.06 mPa·s) and film thickness, resulting in sustained skin permeation (permeation rate of 0.348 ± 0.157 ng/cm2 h), and even the pH of the sample with Eudragit® NE 30D, along with higher surface roughness and thermal analysis, implied its immediate delivery through the epidermal membrane. Therefore, this study revealed the utility of several methods able to refine the number of needed tests within the final product profile.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study",
volume = "23",
number = "11",
doi = "10.3390/ijms23116013"
}
Timotijević, M., Ilić, T., Marković, B., Randjelović, D., Cekić, N., Nikolić, I., Savić, S.,& Pantelić, I.. (2022). Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study. in International Journal of Molecular Sciences
MDPI., 23(11).
https://doi.org/10.3390/ijms23116013
Timotijević M, Ilić T, Marković B, Randjelović D, Cekić N, Nikolić I, Savić S, Pantelić I. Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study. in International Journal of Molecular Sciences. 2022;23(11).
doi:10.3390/ijms23116013 .
Timotijević, Mirjana, Ilić, Tanja, Marković, Bojan, Randjelović, Danijela, Cekić, Nebojša, Nikolić, Ines, Savić, Snežana, Pantelić, Ivana, "Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study" in International Journal of Molecular Sciences, 23, no. 11 (2022),
https://doi.org/10.3390/ijms23116013 . .
1
1
1

Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3

Mitrović, Jelena; Petković, Miloš; Randjelović, Danijela; Đoković, Jelena; Knutson, Daniel; Cook, James; Savić, Vladimir; Savić, Miroslav; Savić, Snežana

(2022)

TY  - CONF
AU  - Mitrović, Jelena
AU  - Petković, Miloš
AU  - Randjelović, Danijela
AU  - Đoković, Jelena
AU  - Knutson, Daniel
AU  - Cook, James
AU  - Savić, Vladimir
AU  - Savić, Miroslav
AU  - Savić, Snežana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5259
AB  - Poster presented at 13th World meeting on pharmaceutics, biopharmaceutics and pharmaceutical technology, 28-31 March 2022, Rotterdam, Netherlands
T1  - Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3
UR  - https://hdl.handle.net/21.15107/rcub_cer_5259
ER  - 
@conference{
author = "Mitrović, Jelena and Petković, Miloš and Randjelović, Danijela and Đoković, Jelena and Knutson, Daniel and Cook, James and Savić, Vladimir and Savić, Miroslav and Savić, Snežana",
year = "2022",
abstract = "Poster presented at 13th World meeting on pharmaceutics, biopharmaceutics and pharmaceutical technology, 28-31 March 2022, Rotterdam, Netherlands",
title = "Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3",
url = "https://hdl.handle.net/21.15107/rcub_cer_5259"
}
Mitrović, J., Petković, M., Randjelović, D., Đoković, J., Knutson, D., Cook, J., Savić, V., Savić, M.,& Savić, S.. (2022). Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3. .
https://hdl.handle.net/21.15107/rcub_cer_5259
Mitrović J, Petković M, Randjelović D, Đoković J, Knutson D, Cook J, Savić V, Savić M, Savić S. Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3. 2022;.
https://hdl.handle.net/21.15107/rcub_cer_5259 .
Mitrović, Jelena, Petković, Miloš, Randjelović, Danijela, Đoković, Jelena, Knutson, Daniel, Cook, James, Savić, Vladimir, Savić, Miroslav, Savić, Snežana, "Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3" (2022),
https://hdl.handle.net/21.15107/rcub_cer_5259 .

Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye

Joksimović, Kristina; Kodranov, Igor; Randjelović, Danijela; Slavković Beškoski, Latinka; Radulović, Jelena; Lješević, Marija; Manojlović, Dragan; Beškoski, Vladimir

(Elsevier, 2022)

TY  - JOUR
AU  - Joksimović, Kristina
AU  - Kodranov, Igor
AU  - Randjelović, Danijela
AU  - Slavković Beškoski, Latinka
AU  - Radulović, Jelena
AU  - Lješević, Marija
AU  - Manojlović, Dragan
AU  - Beškoski, Vladimir
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4942
AB  - The problem of wastewater has long been ubiquitous and has great consequences for the environment and its
inhabitants. Microbial fuel cells (MFCs) have enormous potential for the treatment of wastewaters polluted with
azo dyes. The amount of energy that can be produced from a single-chamber MFC is sufficient to perform
decolorization and degradation of such dyes, which are widely used in the textile industry. This study on the azo
dye, reactive black 5 (RB5), provides an alternative method through three parallel-connected MFCs to obtain
electricity that directly serves for the dye’s electrochemical degradation. We examined degradation followed by
decolorization of RB5 using Fe and Pt electrodes, together with H2O2, to achieve the electro-Fenton process. The
amount of voltage produced (295 mV), the current density (276 mA m− 3
) and the power density (50 mW m− 3
)
were sufficient to degrade 25 mg L-1 RB5 dye with 0.5 mM H2O2 in just 2 h. The dye degradation mechanism was
investigated using UV–VIS, FT-IR and HPLC-MS/MS. The ecotoxicity of the degradation products was assessed
using a bacterial model, Aliivibrio fischeri. These tests showed that there was successful degradation of the dye to
products whose toxicity is less than that of RB5.
PB  - Elsevier
T2  - Bioelectrochemistry
T1  - Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye
VL  - 145
SP  - 108088
DO  - 10.1016/j.bioelechem.2022.108088
ER  - 
@article{
author = "Joksimović, Kristina and Kodranov, Igor and Randjelović, Danijela and Slavković Beškoski, Latinka and Radulović, Jelena and Lješević, Marija and Manojlović, Dragan and Beškoski, Vladimir",
year = "2022",
abstract = "The problem of wastewater has long been ubiquitous and has great consequences for the environment and its
inhabitants. Microbial fuel cells (MFCs) have enormous potential for the treatment of wastewaters polluted with
azo dyes. The amount of energy that can be produced from a single-chamber MFC is sufficient to perform
decolorization and degradation of such dyes, which are widely used in the textile industry. This study on the azo
dye, reactive black 5 (RB5), provides an alternative method through three parallel-connected MFCs to obtain
electricity that directly serves for the dye’s electrochemical degradation. We examined degradation followed by
decolorization of RB5 using Fe and Pt electrodes, together with H2O2, to achieve the electro-Fenton process. The
amount of voltage produced (295 mV), the current density (276 mA m− 3
) and the power density (50 mW m− 3
)
were sufficient to degrade 25 mg L-1 RB5 dye with 0.5 mM H2O2 in just 2 h. The dye degradation mechanism was
investigated using UV–VIS, FT-IR and HPLC-MS/MS. The ecotoxicity of the degradation products was assessed
using a bacterial model, Aliivibrio fischeri. These tests showed that there was successful degradation of the dye to
products whose toxicity is less than that of RB5.",
publisher = "Elsevier",
journal = "Bioelectrochemistry",
title = "Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye",
volume = "145",
pages = "108088",
doi = "10.1016/j.bioelechem.2022.108088"
}
Joksimović, K., Kodranov, I., Randjelović, D., Slavković Beškoski, L., Radulović, J., Lješević, M., Manojlović, D.,& Beškoski, V.. (2022). Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye. in Bioelectrochemistry
Elsevier., 145, 108088.
https://doi.org/10.1016/j.bioelechem.2022.108088
Joksimović K, Kodranov I, Randjelović D, Slavković Beškoski L, Radulović J, Lješević M, Manojlović D, Beškoski V. Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye. in Bioelectrochemistry. 2022;145:108088.
doi:10.1016/j.bioelechem.2022.108088 .
Joksimović, Kristina, Kodranov, Igor, Randjelović, Danijela, Slavković Beškoski, Latinka, Radulović, Jelena, Lješević, Marija, Manojlović, Dragan, Beškoski, Vladimir, "Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye" in Bioelectrochemistry, 145 (2022):108088,
https://doi.org/10.1016/j.bioelechem.2022.108088 . .
14
10
13

The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions

Đoković, Jelena B.; Demisli, Sotiria; Savić, Sanela M.; Marković, Bojan D.; Cekić, Nebojša D.; Randjelović, Danijela; Mitrović, Jelena R.; Lunter, Dominique Jasmin; Papadimitriou, Vassiliki; Xenakis, Aristotelis; Savić, Snežana D.

(Switzerland : Multidisciplinary Digital Publishing Institute (MDPI), 2022)

TY  - JOUR
AU  - Đoković, Jelena B.
AU  - Demisli, Sotiria
AU  - Savić, Sanela M.
AU  - Marković, Bojan D.
AU  - Cekić, Nebojša D.
AU  - Randjelović, Danijela
AU  - Mitrović, Jelena R.
AU  - Lunter, Dominique Jasmin
AU  - Papadimitriou, Vassiliki
AU  - Xenakis, Aristotelis
AU  - Savić, Snežana D.
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5375
AB  - A nanotechnology-based approach to drug delivery presents one of the biggest trends in biomedical science that can provide increased active concentration, bioavailability, and safety compared to conventional drug-delivery systems. Nanoemulsions stand out amongst other nanocarriers for being biodegradable, biocompatible, and relatively easy to manufacture. For improved drug-delivery properties, longer circulation for the nanoemulsion droplets should be provided, to allow the active to reach the target site. One of the strategies used for this purpose is PEGylation. The aim of this research was assessing the impact of the oil phase selection, soybean or fish oil mixtures with medium chain triglycerides, on the physicochemical characteristics and injectability of curcumin-loaded PEGylated nanoemulsions. Electron paramagnetic resonance spectroscopy demonstrated the structural impact of the oil phase on the stabilizing layer of nanoemulsions, with a more pronounced stabilizing effect of curcumin observed in the fish oil nanoemulsion compared to the soybean oil one. The design of the experiment study, employed to simultaneously assess the impact of the oil phase, different PEGylated phospholipids and their concentrations, as well as the presence of curcumin, showed that not only the investigated factors alone, but also their interactions, had a significant influence on the critical quality attributes of the PEGylated nanoemulsions. Detailed physicochemical characterization of the NEs found all formulations were appropriate for parenteral administration and remained stable during two years of storage, with the preserved antioxidant activity demonstrated by DPPH and FRAP assays. In vitro release studies showed a more pronounced release of curcumin from the fish oil NEs compared to that from the soybean oil ones. The innovative in vitro injectability assessment, designed to mimic intravenous application, proved that all formulations tested in selected experimental setting could be employed in prospective in vivo studies. Overall, the current study shows the importance of oil phase selection when formulating PEGylated nanoemulsions.
PB  - Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)
T2  - Pharmaceutics
T1  - The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions
VL  - 14
IS  - 8
SP  - 1666
DO  - 10.3390/pharmaceutics14081666
ER  - 
@article{
author = "Đoković, Jelena B. and Demisli, Sotiria and Savić, Sanela M. and Marković, Bojan D. and Cekić, Nebojša D. and Randjelović, Danijela and Mitrović, Jelena R. and Lunter, Dominique Jasmin and Papadimitriou, Vassiliki and Xenakis, Aristotelis and Savić, Snežana D.",
year = "2022",
abstract = "A nanotechnology-based approach to drug delivery presents one of the biggest trends in biomedical science that can provide increased active concentration, bioavailability, and safety compared to conventional drug-delivery systems. Nanoemulsions stand out amongst other nanocarriers for being biodegradable, biocompatible, and relatively easy to manufacture. For improved drug-delivery properties, longer circulation for the nanoemulsion droplets should be provided, to allow the active to reach the target site. One of the strategies used for this purpose is PEGylation. The aim of this research was assessing the impact of the oil phase selection, soybean or fish oil mixtures with medium chain triglycerides, on the physicochemical characteristics and injectability of curcumin-loaded PEGylated nanoemulsions. Electron paramagnetic resonance spectroscopy demonstrated the structural impact of the oil phase on the stabilizing layer of nanoemulsions, with a more pronounced stabilizing effect of curcumin observed in the fish oil nanoemulsion compared to the soybean oil one. The design of the experiment study, employed to simultaneously assess the impact of the oil phase, different PEGylated phospholipids and their concentrations, as well as the presence of curcumin, showed that not only the investigated factors alone, but also their interactions, had a significant influence on the critical quality attributes of the PEGylated nanoemulsions. Detailed physicochemical characterization of the NEs found all formulations were appropriate for parenteral administration and remained stable during two years of storage, with the preserved antioxidant activity demonstrated by DPPH and FRAP assays. In vitro release studies showed a more pronounced release of curcumin from the fish oil NEs compared to that from the soybean oil ones. The innovative in vitro injectability assessment, designed to mimic intravenous application, proved that all formulations tested in selected experimental setting could be employed in prospective in vivo studies. Overall, the current study shows the importance of oil phase selection when formulating PEGylated nanoemulsions.",
publisher = "Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "Pharmaceutics",
title = "The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions",
volume = "14",
number = "8",
pages = "1666",
doi = "10.3390/pharmaceutics14081666"
}
Đoković, J. B., Demisli, S., Savić, S. M., Marković, B. D., Cekić, N. D., Randjelović, D., Mitrović, J. R., Lunter, D. J., Papadimitriou, V., Xenakis, A.,& Savić, S. D.. (2022). The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions. in Pharmaceutics
Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)., 14(8), 1666.
https://doi.org/10.3390/pharmaceutics14081666
Đoković JB, Demisli S, Savić SM, Marković BD, Cekić ND, Randjelović D, Mitrović JR, Lunter DJ, Papadimitriou V, Xenakis A, Savić SD. The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions. in Pharmaceutics. 2022;14(8):1666.
doi:10.3390/pharmaceutics14081666 .
Đoković, Jelena B., Demisli, Sotiria, Savić, Sanela M., Marković, Bojan D., Cekić, Nebojša D., Randjelović, Danijela, Mitrović, Jelena R., Lunter, Dominique Jasmin, Papadimitriou, Vassiliki, Xenakis, Aristotelis, Savić, Snežana D., "The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions" in Pharmaceutics, 14, no. 8 (2022):1666,
https://doi.org/10.3390/pharmaceutics14081666 . .
6
6
6

Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms

Đukanović, Stefana; Ganić, Tea; Lončarević, Branka; Cvetković, Stefana; Nikolić, Biljana; Tenji, Dina; Randjelović, Danijela; Mitić-Ćulafić, Dragana

(Wiley, 2022)

TY  - JOUR
AU  - Đukanović, Stefana
AU  - Ganić, Tea
AU  - Lončarević, Branka
AU  - Cvetković, Stefana
AU  - Nikolić, Biljana
AU  - Tenji, Dina
AU  - Randjelović, Danijela
AU  - Mitić-Ćulafić, Dragana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5590
AB  - Aims Because the Staphylococcus aureus is one of the most well‐known pathogens associated with medical devices and nosocomial infections, the aim of the study was to examine antibiofilm potential of emodin against it.  Methods and Results Antibacterial activity was examined through microdilution assay. Antibiofilm testing included crystal violet staining of biofilm biomass and morphology analysis by Atomic force microscopy (AFM). Furthermore, aerobic respiration was monitored using the Micro‐Oxymax respirometer. For investigation of gene expression qRT‐PCR was performed. Emodin demonstrated strong antibacterial activity and ability to inhibit biofilm formation of all tested strains. The effect on preformed biofilms was spotted in few strains. AFM revealed that emodin affects biofilm structure and roughness. Monitoring of respiration under emodin treatment in planktonic and biofilm form revealed that emodin influenced aerobic respiration. Moreover, qRT‐PCR showed that emodin modulates expression of icaA, icaD, srrA and srrB genes, as well as RNAIII, and that this activity was strain‐specific.  Conclusion The results obtained in this study indicate the novel antibiofilm activity of emodin and its multiple pathways of action.  Significance and Impact of Study This is the first study that examined pathways through which emodin expressed its antibiofilm activity
PB  - Wiley
T2  - Journal of Applied Microbiology
T1  - Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms
VL  - 132
IS  - 3
SP  - 1840
EP  - 1855
DO  - 10.1111/jam.15360
ER  - 
@article{
author = "Đukanović, Stefana and Ganić, Tea and Lončarević, Branka and Cvetković, Stefana and Nikolić, Biljana and Tenji, Dina and Randjelović, Danijela and Mitić-Ćulafić, Dragana",
year = "2022",
abstract = "Aims Because the Staphylococcus aureus is one of the most well‐known pathogens associated with medical devices and nosocomial infections, the aim of the study was to examine antibiofilm potential of emodin against it.  Methods and Results Antibacterial activity was examined through microdilution assay. Antibiofilm testing included crystal violet staining of biofilm biomass and morphology analysis by Atomic force microscopy (AFM). Furthermore, aerobic respiration was monitored using the Micro‐Oxymax respirometer. For investigation of gene expression qRT‐PCR was performed. Emodin demonstrated strong antibacterial activity and ability to inhibit biofilm formation of all tested strains. The effect on preformed biofilms was spotted in few strains. AFM revealed that emodin affects biofilm structure and roughness. Monitoring of respiration under emodin treatment in planktonic and biofilm form revealed that emodin influenced aerobic respiration. Moreover, qRT‐PCR showed that emodin modulates expression of icaA, icaD, srrA and srrB genes, as well as RNAIII, and that this activity was strain‐specific.  Conclusion The results obtained in this study indicate the novel antibiofilm activity of emodin and its multiple pathways of action.  Significance and Impact of Study This is the first study that examined pathways through which emodin expressed its antibiofilm activity",
publisher = "Wiley",
journal = "Journal of Applied Microbiology",
title = "Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms",
volume = "132",
number = "3",
pages = "1840-1855",
doi = "10.1111/jam.15360"
}
Đukanović, S., Ganić, T., Lončarević, B., Cvetković, S., Nikolić, B., Tenji, D., Randjelović, D.,& Mitić-Ćulafić, D.. (2022). Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms. in Journal of Applied Microbiology
Wiley., 132(3), 1840-1855.
https://doi.org/10.1111/jam.15360
Đukanović S, Ganić T, Lončarević B, Cvetković S, Nikolić B, Tenji D, Randjelović D, Mitić-Ćulafić D. Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms. in Journal of Applied Microbiology. 2022;132(3):1840-1855.
doi:10.1111/jam.15360 .
Đukanović, Stefana, Ganić, Tea, Lončarević, Branka, Cvetković, Stefana, Nikolić, Biljana, Tenji, Dina, Randjelović, Danijela, Mitić-Ćulafić, Dragana, "Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms" in Journal of Applied Microbiology, 132, no. 3 (2022):1840-1855,
https://doi.org/10.1111/jam.15360 . .
2
13
13
14

Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin

Lončarević, Branka; Nikolić, Vladimir; Randjelović, Danijela; Poljak, Predrag; Gojgić-Cvijović, Gordana; Beškoski, Vladimir

(COST Action 19124, 2022)

TY  - CONF
AU  - Lončarević, Branka
AU  - Nikolić, Vladimir
AU  - Randjelović, Danijela
AU  - Poljak, Predrag
AU  - Gojgić-Cvijović, Gordana
AU  - Beškoski, Vladimir
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5720
AB  - Food packaging ensures safety and hygiene, while reducing food waste, therefore it is and ssential component of the food supply chain. A sustainable and biodegradable alternative to conventional food packaging is edible packaging which contributes to the reducing waste and the economic efficiency of packaging materials. The numerous biopolymeric materials could be used as source such as polysaccharides (starch, cellulose, chitosan) and proteins (gelatin, soy protein, whey). Exopolysaccharides (EPS) are fermentation-based biopolyrners, secreted outside the cell wall and synthesized by various microbial species including bacteria, fungi and blue-green algae. Microbial levan is fructose-based EPS and convenient due to its biocornpatibility, renewability, high molecular weight, low viscous nature, antioxidant and prebiotic effects. Levan used in this work was produced by the B. licheniformis NS032 strain and its hydrophobic derivatives were obtained using octenyl succinic anhydride (OSA). Degree of substitution (DS) for modified levans were 0.025 and 0.032 for LH22 and LH25 respectively. Three different film compositions were prepared: 
levan/LH22/LH26 with gelatin in proportions 1:1. Films were prepared by casting technique and evaporated at room temperature. Morphology of the obtained films were studied by ARV (Atomic force microscopy), AutoProbe CP-Research SPM (TM Microscopes-Broker) and mechanical properties were examined by Shimodzu E2-LX tensile tester. The samples had thickness of 150 trrrl. Based on morphological measurements, it can be concluded that use of levan derivatives change roughness of the levan/gelatin blend film. The best mechanical properties (tensile strength and elongation at break) were obtained with pure levan. Obtained films are composed from edible and biodegradable components and therefore are potentially applicable in food industry. Future investigation will be focused on optimization of levan/gelatin proportion and more extensive 
structural and mechanical properties of obtained films.
PB  - COST Action 19124
PB  - Ljubljana, Slovenia : Pulp and Paper Institute
C3  - Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana
T1  - Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin
SP  - 109
EP  - 110
UR  - https://hdl.handle.net/21.15107/rcub_cer_5720
ER  - 
@conference{
author = "Lončarević, Branka and Nikolić, Vladimir and Randjelović, Danijela and Poljak, Predrag and Gojgić-Cvijović, Gordana and Beškoski, Vladimir",
year = "2022",
abstract = "Food packaging ensures safety and hygiene, while reducing food waste, therefore it is and ssential component of the food supply chain. A sustainable and biodegradable alternative to conventional food packaging is edible packaging which contributes to the reducing waste and the economic efficiency of packaging materials. The numerous biopolymeric materials could be used as source such as polysaccharides (starch, cellulose, chitosan) and proteins (gelatin, soy protein, whey). Exopolysaccharides (EPS) are fermentation-based biopolyrners, secreted outside the cell wall and synthesized by various microbial species including bacteria, fungi and blue-green algae. Microbial levan is fructose-based EPS and convenient due to its biocornpatibility, renewability, high molecular weight, low viscous nature, antioxidant and prebiotic effects. Levan used in this work was produced by the B. licheniformis NS032 strain and its hydrophobic derivatives were obtained using octenyl succinic anhydride (OSA). Degree of substitution (DS) for modified levans were 0.025 and 0.032 for LH22 and LH25 respectively. Three different film compositions were prepared: 
levan/LH22/LH26 with gelatin in proportions 1:1. Films were prepared by casting technique and evaporated at room temperature. Morphology of the obtained films were studied by ARV (Atomic force microscopy), AutoProbe CP-Research SPM (TM Microscopes-Broker) and mechanical properties were examined by Shimodzu E2-LX tensile tester. The samples had thickness of 150 trrrl. Based on morphological measurements, it can be concluded that use of levan derivatives change roughness of the levan/gelatin blend film. The best mechanical properties (tensile strength and elongation at break) were obtained with pure levan. Obtained films are composed from edible and biodegradable components and therefore are potentially applicable in food industry. Future investigation will be focused on optimization of levan/gelatin proportion and more extensive 
structural and mechanical properties of obtained films.",
publisher = "COST Action 19124, Ljubljana, Slovenia : Pulp and Paper Institute",
journal = "Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana",
title = "Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin",
pages = "109-110",
url = "https://hdl.handle.net/21.15107/rcub_cer_5720"
}
Lončarević, B., Nikolić, V., Randjelović, D., Poljak, P., Gojgić-Cvijović, G.,& Beškoski, V.. (2022). Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin. in Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana
COST Action 19124., 109-110.
https://hdl.handle.net/21.15107/rcub_cer_5720
Lončarević B, Nikolić V, Randjelović D, Poljak P, Gojgić-Cvijović G, Beškoski V. Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin. in Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana. 2022;:109-110.
https://hdl.handle.net/21.15107/rcub_cer_5720 .
Lončarević, Branka, Nikolić, Vladimir, Randjelović, Danijela, Poljak, Predrag, Gojgić-Cvijović, Gordana, Beškoski, Vladimir, "Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin" in Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana (2022):109-110,
https://hdl.handle.net/21.15107/rcub_cer_5720 .

Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments

Randjelović, Danijela; Joksimović, Kristina; Kodranov, Igor; Žerađanin, Aleksandra; Popović, Bogdan; Poljak, Predrag; Manojlović, Dragan; Beškoski, Vladimir

(Institute of Electrical and Electronics Engineers Inc (IEEE), 2022)

TY  - CONF
AU  - Randjelović, Danijela
AU  - Joksimović, Kristina
AU  - Kodranov, Igor
AU  - Žerađanin, Aleksandra
AU  - Popović, Bogdan
AU  - Poljak, Predrag
AU  - Manojlović, Dragan
AU  - Beškoski, Vladimir
PY  - 2022
UR  - https://ieeexplore.ieee.org/document/9934706
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5857
AB  - This paper gives overview of research activities, performed by our team, in the field of Microbial Fuel Cells (MFCs). Evolution of construction, performance and application of MFCs is presented. The path towards optimization of the performance led through design and construction of the cell and was followed by investigation of impact of different sediments containing different microbial communities. The sediment samples were collected from two locations in Serbia, confluence of rivers Sava and Danube in Belgrade and the acid mine drainage lake "Robule" in the copper mine Bor. Results of verified application in wastewater treatment are discussed.
PB  - Institute of Electrical and Electronics Engineers Inc (IEEE)
C3  - Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania
T1  - Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments
SP  - 30
EP  - 37
DO  - 10.1109/CAS56377.2022.9934706
ER  - 
@conference{
author = "Randjelović, Danijela and Joksimović, Kristina and Kodranov, Igor and Žerađanin, Aleksandra and Popović, Bogdan and Poljak, Predrag and Manojlović, Dragan and Beškoski, Vladimir",
year = "2022",
abstract = "This paper gives overview of research activities, performed by our team, in the field of Microbial Fuel Cells (MFCs). Evolution of construction, performance and application of MFCs is presented. The path towards optimization of the performance led through design and construction of the cell and was followed by investigation of impact of different sediments containing different microbial communities. The sediment samples were collected from two locations in Serbia, confluence of rivers Sava and Danube in Belgrade and the acid mine drainage lake "Robule" in the copper mine Bor. Results of verified application in wastewater treatment are discussed.",
publisher = "Institute of Electrical and Electronics Engineers Inc (IEEE)",
journal = "Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania",
title = "Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments",
pages = "30-37",
doi = "10.1109/CAS56377.2022.9934706"
}
Randjelović, D., Joksimović, K., Kodranov, I., Žerađanin, A., Popović, B., Poljak, P., Manojlović, D.,& Beškoski, V.. (2022). Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments. in Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania
Institute of Electrical and Electronics Engineers Inc (IEEE)., 30-37.
https://doi.org/10.1109/CAS56377.2022.9934706
Randjelović D, Joksimović K, Kodranov I, Žerađanin A, Popović B, Poljak P, Manojlović D, Beškoski V. Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments. in Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania. 2022;:30-37.
doi:10.1109/CAS56377.2022.9934706 .
Randjelović, Danijela, Joksimović, Kristina, Kodranov, Igor, Žerađanin, Aleksandra, Popović, Bogdan, Poljak, Predrag, Manojlović, Dragan, Beškoski, Vladimir, "Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments" in Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania (2022):30-37,
https://doi.org/10.1109/CAS56377.2022.9934706 . .

Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach

Mitrović, Jelena; Divović-Matović, Branka; Knutson, Daniel E.; Ðoković, Jelena B.; Kremenović, Aleksandar; Dobričić, Vladimir; Randjelović, Danijela; Pantelić, Ivana; Cook, James; Savić, Miroslav M.; Savić, Snežana D.

(MDPI, 2021)

TY  - JOUR
AU  - Mitrović, Jelena
AU  - Divović-Matović, Branka
AU  - Knutson, Daniel E.
AU  - Ðoković, Jelena B.
AU  - Kremenović, Aleksandar
AU  - Dobričić, Vladimir
AU  - Randjelović, Danijela
AU  - Pantelić, Ivana
AU  - Cook, James
AU  - Savić, Miroslav M.
AU  - Savić, Snežana D.
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4791
AB  - Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric disorders. In this research, based on preformulation studies, nanocrystal technology was chosen to improve the oral bioavailability of DK-I-60-3. Nanocrystal dispersions stabilized by sodium lauryl sulfate and polyvinylpyrrolidone were prepared by modified wet media milling technique, with the selection of appropriate process and formulation parameters. The nanoparticles characterization included particle size and zeta potential measurements, differential scanning calorimetry, X-ray powder diffraction, dissolution and solubility study, and in vivo pharmacokinetic experiments. Developed formulations had small uniform particle sizes and were stable for three months. Nanonization caused decreased crystallite size and induced crystal defects formation, as well as a DK-I-60-3 solubility increase. Furthermore, after oral administration of the developed formulations in rats, two to three-fold bioavailability enhancement was observed in plasma and investigated organs, including the brain.
PB  - MDPI
T2  - Pharmaceutics
T1  - Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach
VL  - 13
IS  - 8
SP  - 1188
DO  - 10.3390/pharmaceutics13081188
ER  - 
@article{
author = "Mitrović, Jelena and Divović-Matović, Branka and Knutson, Daniel E. and Ðoković, Jelena B. and Kremenović, Aleksandar and Dobričić, Vladimir and Randjelović, Danijela and Pantelić, Ivana and Cook, James and Savić, Miroslav M. and Savić, Snežana D.",
year = "2021",
abstract = "Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric disorders. In this research, based on preformulation studies, nanocrystal technology was chosen to improve the oral bioavailability of DK-I-60-3. Nanocrystal dispersions stabilized by sodium lauryl sulfate and polyvinylpyrrolidone were prepared by modified wet media milling technique, with the selection of appropriate process and formulation parameters. The nanoparticles characterization included particle size and zeta potential measurements, differential scanning calorimetry, X-ray powder diffraction, dissolution and solubility study, and in vivo pharmacokinetic experiments. Developed formulations had small uniform particle sizes and were stable for three months. Nanonization caused decreased crystallite size and induced crystal defects formation, as well as a DK-I-60-3 solubility increase. Furthermore, after oral administration of the developed formulations in rats, two to three-fold bioavailability enhancement was observed in plasma and investigated organs, including the brain.",
publisher = "MDPI",
journal = "Pharmaceutics",
title = "Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach",
volume = "13",
number = "8",
pages = "1188",
doi = "10.3390/pharmaceutics13081188"
}
Mitrović, J., Divović-Matović, B., Knutson, D. E., Ðoković, J. B., Kremenović, A., Dobričić, V., Randjelović, D., Pantelić, I., Cook, J., Savić, M. M.,& Savić, S. D.. (2021). Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach. in Pharmaceutics
MDPI., 13(8), 1188.
https://doi.org/10.3390/pharmaceutics13081188
Mitrović J, Divović-Matović B, Knutson DE, Ðoković JB, Kremenović A, Dobričić V, Randjelović D, Pantelić I, Cook J, Savić MM, Savić SD. Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach. in Pharmaceutics. 2021;13(8):1188.
doi:10.3390/pharmaceutics13081188 .
Mitrović, Jelena, Divović-Matović, Branka, Knutson, Daniel E., Ðoković, Jelena B., Kremenović, Aleksandar, Dobričić, Vladimir, Randjelović, Danijela, Pantelić, Ivana, Cook, James, Savić, Miroslav M., Savić, Snežana D., "Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach" in Pharmaceutics, 13, no. 8 (2021):1188,
https://doi.org/10.3390/pharmaceutics13081188 . .
7
6
8

Decolorisation of the textile dye using microbial fuel cells as an electricity source

Joksimović, Kristina; Kodranov, Igor; Žerađanin, Aleksandra; Randjelović, Danijela; Popović, Bogdan; Manojlović, Dragan; Nakano, Takeshi; Beškoski, Vladimir

(Japan Society for Environmental Chemistry, 2021)

TY  - CONF
AU  - Joksimović, Kristina
AU  - Kodranov, Igor
AU  - Žerađanin, Aleksandra
AU  - Randjelović, Danijela
AU  - Popović, Bogdan
AU  - Manojlović, Dragan
AU  - Nakano, Takeshi
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5071
AB  - Microbial fuel cells are increasingly used as alternative energy sources. The amount of electricity produced by MFC systems is sufficient to run systems that do not require high energy consumption, such as electrochemical decomposition of wastewater from the textile dye industry. The aim of this study was to analyze the voltage and current of two parallelly-connected MFC cells used for decolorisation of the wastewater that contained Reactive Black 5 (RB5) dye.
PB  - Japan Society for Environmental Chemistry
C3  - 29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan)
T1  - Decolorisation of the textile dye using microbial fuel cells as an electricity source
SP  - 275
UR  - https://hdl.handle.net/21.15107/rcub_cer_5071
ER  - 
@conference{
author = "Joksimović, Kristina and Kodranov, Igor and Žerađanin, Aleksandra and Randjelović, Danijela and Popović, Bogdan and Manojlović, Dragan and Nakano, Takeshi and Beškoski, Vladimir",
year = "2021",
abstract = "Microbial fuel cells are increasingly used as alternative energy sources. The amount of electricity produced by MFC systems is sufficient to run systems that do not require high energy consumption, such as electrochemical decomposition of wastewater from the textile dye industry. The aim of this study was to analyze the voltage and current of two parallelly-connected MFC cells used for decolorisation of the wastewater that contained Reactive Black 5 (RB5) dye.",
publisher = "Japan Society for Environmental Chemistry",
journal = "29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan)",
title = "Decolorisation of the textile dye using microbial fuel cells as an electricity source",
pages = "275",
url = "https://hdl.handle.net/21.15107/rcub_cer_5071"
}
Joksimović, K., Kodranov, I., Žerađanin, A., Randjelović, D., Popović, B., Manojlović, D., Nakano, T.,& Beškoski, V.. (2021). Decolorisation of the textile dye using microbial fuel cells as an electricity source. in 29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan)
Japan Society for Environmental Chemistry., 275.
https://hdl.handle.net/21.15107/rcub_cer_5071
Joksimović K, Kodranov I, Žerađanin A, Randjelović D, Popović B, Manojlović D, Nakano T, Beškoski V. Decolorisation of the textile dye using microbial fuel cells as an electricity source. in 29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan). 2021;:275.
https://hdl.handle.net/21.15107/rcub_cer_5071 .
Joksimović, Kristina, Kodranov, Igor, Žerađanin, Aleksandra, Randjelović, Danijela, Popović, Bogdan, Manojlović, Dragan, Nakano, Takeshi, Beškoski, Vladimir, "Decolorisation of the textile dye using microbial fuel cells as an electricity source" in 29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan) (2021):275,
https://hdl.handle.net/21.15107/rcub_cer_5071 .

Power generation using parallel connected microbial fuel cells systems

Joksimović, Kristina; Žerađanin, Aleksandra; Lješević, Marija; Lončarević, Branka; Randjelović, Danijela; Beškoski, Vladimir

(India : SRM Research Institute, 2021)

TY  - CONF
AU  - Joksimović, Kristina
AU  - Žerađanin, Aleksandra
AU  - Lješević, Marija
AU  - Lončarević, Branka
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5102
AB  - The use of microbial fuel cells (MFCs) for the purpose of obtaining energy from nature has 
grown in the second decade of the 21st century. Due to the lack of fossil fuels and less and less available renewable energy sources, MFCs have great potential for obtaining small amounts of electricity. Increasing attention is focused on the use of such types of energy. The aim of this paper is to analyse the current generation of two parallel-connected MFC cells and the power generation obtained in this way.
PB  - India : SRM Research Institute
C3  - International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual)
T1  - Power generation using parallel connected microbial fuel cells systems
SP  - 26
UR  - https://hdl.handle.net/21.15107/rcub_cer_5102
ER  - 
@conference{
author = "Joksimović, Kristina and Žerađanin, Aleksandra and Lješević, Marija and Lončarević, Branka and Randjelović, Danijela and Beškoski, Vladimir",
year = "2021",
abstract = "The use of microbial fuel cells (MFCs) for the purpose of obtaining energy from nature has 
grown in the second decade of the 21st century. Due to the lack of fossil fuels and less and less available renewable energy sources, MFCs have great potential for obtaining small amounts of electricity. Increasing attention is focused on the use of such types of energy. The aim of this paper is to analyse the current generation of two parallel-connected MFC cells and the power generation obtained in this way.",
publisher = "India : SRM Research Institute",
journal = "International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual)",
title = "Power generation using parallel connected microbial fuel cells systems",
pages = "26",
url = "https://hdl.handle.net/21.15107/rcub_cer_5102"
}
Joksimović, K., Žerađanin, A., Lješević, M., Lončarević, B., Randjelović, D.,& Beškoski, V.. (2021). Power generation using parallel connected microbial fuel cells systems. in International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual)
India : SRM Research Institute., 26.
https://hdl.handle.net/21.15107/rcub_cer_5102
Joksimović K, Žerađanin A, Lješević M, Lončarević B, Randjelović D, Beškoski V. Power generation using parallel connected microbial fuel cells systems. in International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual). 2021;:26.
https://hdl.handle.net/21.15107/rcub_cer_5102 .
Joksimović, Kristina, Žerađanin, Aleksandra, Lješević, Marija, Lončarević, Branka, Randjelović, Danijela, Beškoski, Vladimir, "Power generation using parallel connected microbial fuel cells systems" in International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual) (2021):26,
https://hdl.handle.net/21.15107/rcub_cer_5102 .

Influence of Microbial Community on Power generation Using MFC System

Joksimović, Kristina; Žerađanin, Aleksandra; Lončarević, Branka; Lješević, Marija; Avdalović, Jelena; Randjelović, Danijela; Beškoski, Vladimir

(Belgrade : Serbian Chemical Society, 2021)

TY  - CONF
AU  - Joksimović, Kristina
AU  - Žerađanin, Aleksandra
AU  - Lončarević, Branka
AU  - Lješević, Marija
AU  - Avdalović, Jelena
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5014
AB  - Global worldwide population and urbanization in general have created an increasing need for new energy sources. These sources need to be renewable, but it is also very important to respect the principles of environmental protection. Microbial fuel cells (MFC) are a green technology that has been attracting more and more attention in the last decade. MFC presents a system that produces electrical current through metabolic processes of microorganisms, such as the decomposition of organic matter. In this process, chemical energy is directly converted into electrical energy.
PB  - Belgrade : Serbian Chemical Society
C3  - 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia
T1  - Influence of Microbial Community on Power generation Using MFC System
SP  - 112
UR  - https://hdl.handle.net/21.15107/rcub_cer_5014
ER  - 
@conference{
author = "Joksimović, Kristina and Žerađanin, Aleksandra and Lončarević, Branka and Lješević, Marija and Avdalović, Jelena and Randjelović, Danijela and Beškoski, Vladimir",
year = "2021",
abstract = "Global worldwide population and urbanization in general have created an increasing need for new energy sources. These sources need to be renewable, but it is also very important to respect the principles of environmental protection. Microbial fuel cells (MFC) are a green technology that has been attracting more and more attention in the last decade. MFC presents a system that produces electrical current through metabolic processes of microorganisms, such as the decomposition of organic matter. In this process, chemical energy is directly converted into electrical energy.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia",
title = "Influence of Microbial Community on Power generation Using MFC System",
pages = "112",
url = "https://hdl.handle.net/21.15107/rcub_cer_5014"
}
Joksimović, K., Žerađanin, A., Lončarević, B., Lješević, M., Avdalović, J., Randjelović, D.,& Beškoski, V.. (2021). Influence of Microbial Community on Power generation Using MFC System. in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia
Belgrade : Serbian Chemical Society., 112.
https://hdl.handle.net/21.15107/rcub_cer_5014
Joksimović K, Žerađanin A, Lončarević B, Lješević M, Avdalović J, Randjelović D, Beškoski V. Influence of Microbial Community on Power generation Using MFC System. in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia. 2021;:112.
https://hdl.handle.net/21.15107/rcub_cer_5014 .
Joksimović, Kristina, Žerađanin, Aleksandra, Lončarević, Branka, Lješević, Marija, Avdalović, Jelena, Randjelović, Danijela, Beškoski, Vladimir, "Influence of Microbial Community on Power generation Using MFC System" in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia (2021):112,
https://hdl.handle.net/21.15107/rcub_cer_5014 .

Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate

Jovanov, Vladislav; Sarajlić, Milija; Randjelović, Danijela

(ИХТМ - Центар за микроелектронске технологиjе, Универзитет у Београду, 2021)

TY  - GEN
AU  - Jovanov, Vladislav
AU  - Sarajlić, Milija
AU  - Randjelović, Danijela
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5919
AB  - Ово техничко решење омогућава да се симулира изглед површине танког филма нанешног на текстуирани супстрат. Тако симулирана површина се затим може користити у програму за анализу отвореног угла површине ради анализе потенциjалне поjаве електричних
дефеката, или комерциjалним програмима попут COMSOL и ANSYS Lumerical, ради предвиђања оптичких карактеристика танкослоjних микрокристалних силициjумских ћелиjа
нумеричким путем. Коришћењем овог техничког решења практично се остваруjе виртуелна фабрикациjа танкослоjних соларних ћелиjа чиме се унапређуjе процес оптимизациjе
и значаjно штеди на лабораториjским ресурсима.
PB  - ИХТМ - Центар за микроелектронске технологиjе, Универзитет у Београду
T1  - Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate
UR  - https://hdl.handle.net/21.15107/rcub_cer_5919
ER  - 
@misc{
author = "Jovanov, Vladislav and Sarajlić, Milija and Randjelović, Danijela",
year = "2021",
abstract = "Ово техничко решење омогућава да се симулира изглед површине танког филма нанешног на текстуирани супстрат. Тако симулирана површина се затим може користити у програму за анализу отвореног угла површине ради анализе потенциjалне поjаве електричних
дефеката, или комерциjалним програмима попут COMSOL и ANSYS Lumerical, ради предвиђања оптичких карактеристика танкослоjних микрокристалних силициjумских ћелиjа
нумеричким путем. Коришћењем овог техничког решења практично се остваруjе виртуелна фабрикациjа танкослоjних соларних ћелиjа чиме се унапређуjе процес оптимизациjе
и значаjно штеди на лабораториjским ресурсима.",
publisher = "ИХТМ - Центар за микроелектронске технологиjе, Универзитет у Београду",
title = "Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate",
url = "https://hdl.handle.net/21.15107/rcub_cer_5919"
}
Jovanov, V., Sarajlić, M.,& Randjelović, D.. (2021). Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate. 
ИХТМ - Центар за микроелектронске технологиjе, Универзитет у Београду..
https://hdl.handle.net/21.15107/rcub_cer_5919
Jovanov V, Sarajlić M, Randjelović D. Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate. 2021;.
https://hdl.handle.net/21.15107/rcub_cer_5919 .
Jovanov, Vladislav, Sarajlić, Milija, Randjelović, Danijela, "Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate" (2021),
https://hdl.handle.net/21.15107/rcub_cer_5919 .

Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats

Ðoković, Jelena B.; Savić, Sanela M.; Mitrović, Jelena R.; Nikolić, Ines; Marković, Bojan D.; Randjelović, Danijela; Antić-Stanković, Jelena; Božić, Dragana; Cekić, Nebojša D.; Stevanović, Vladimir; Batinić, Bojan; Aranđelović, Jovana; Savić, Miroslav M.; Savić, Snežana D.

(MDPI, 2021)

TY  - JOUR
AU  - Ðoković, Jelena B.
AU  - Savić, Sanela M.
AU  - Mitrović, Jelena R.
AU  - Nikolić, Ines
AU  - Marković, Bojan D.
AU  - Randjelović, Danijela
AU  - Antić-Stanković, Jelena
AU  - Božić, Dragana
AU  - Cekić, Nebojša D.
AU  - Stevanović, Vladimir
AU  - Batinić, Bojan
AU  - Aranđelović, Jovana
AU  - Savić, Miroslav M.
AU  - Savić, Snežana D.
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4822
AB  - The current study describes the experimental design guided development of PEGylated nanoemulsions as parenteral delivery systems for curcumin, a powerful antioxidant, as well as the evaluation of their physicochemical characteristics and antioxidant activity during the two years of storage. Experimental design setup helped development of nanoemulsion templates with critical quality attributes in line with parenteral application route. Curcumin-loaded nanoemulsions showed mean droplet size about 105 nm, polydispersity index <0.15, zeta potential of −40 mV, and acceptable osmolality of about 550 mOsm/kg. After two years of storage at room temperature, all formulations remained stable. Moreover, antioxidant activity remained intact, as demonstrated by DPPH (IC50 values 0.078–0.075 mg/mL after two years) and FRAPS assays. In vitro release testing proved that PEGylated phospholipids slowed down the curcumin release from nanoemulsions. The nanoemulsion carrier has been proven safe by the MTT test conducted with MRC-5 cell line, and effective on LS cell line. Results from the pharmacokinetic pilot study implied the PEGylated nanoemulsions improved plasma residence of curcumin 20 min after intravenous administration, compared to the non-PEGylated nanoemulsion (two-fold higher) or curcumin solution (three-fold higher). Overall, conclusion suggests that developed PEGylated nanoemulsions present an acceptable delivery system for parenteral administration of curcumin, being effective in preserving its stability and antioxidant capacity at the level highly comparable to the initial findings.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats
VL  - 22
IS  - 15
IS  - 7991
DO  - 10.3390/ijms22157991
ER  - 
@article{
author = "Ðoković, Jelena B. and Savić, Sanela M. and Mitrović, Jelena R. and Nikolić, Ines and Marković, Bojan D. and Randjelović, Danijela and Antić-Stanković, Jelena and Božić, Dragana and Cekić, Nebojša D. and Stevanović, Vladimir and Batinić, Bojan and Aranđelović, Jovana and Savić, Miroslav M. and Savić, Snežana D.",
year = "2021",
abstract = "The current study describes the experimental design guided development of PEGylated nanoemulsions as parenteral delivery systems for curcumin, a powerful antioxidant, as well as the evaluation of their physicochemical characteristics and antioxidant activity during the two years of storage. Experimental design setup helped development of nanoemulsion templates with critical quality attributes in line with parenteral application route. Curcumin-loaded nanoemulsions showed mean droplet size about 105 nm, polydispersity index <0.15, zeta potential of −40 mV, and acceptable osmolality of about 550 mOsm/kg. After two years of storage at room temperature, all formulations remained stable. Moreover, antioxidant activity remained intact, as demonstrated by DPPH (IC50 values 0.078–0.075 mg/mL after two years) and FRAPS assays. In vitro release testing proved that PEGylated phospholipids slowed down the curcumin release from nanoemulsions. The nanoemulsion carrier has been proven safe by the MTT test conducted with MRC-5 cell line, and effective on LS cell line. Results from the pharmacokinetic pilot study implied the PEGylated nanoemulsions improved plasma residence of curcumin 20 min after intravenous administration, compared to the non-PEGylated nanoemulsion (two-fold higher) or curcumin solution (three-fold higher). Overall, conclusion suggests that developed PEGylated nanoemulsions present an acceptable delivery system for parenteral administration of curcumin, being effective in preserving its stability and antioxidant capacity at the level highly comparable to the initial findings.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats",
volume = "22",
number = "15, 7991",
doi = "10.3390/ijms22157991"
}
Ðoković, J. B., Savić, S. M., Mitrović, J. R., Nikolić, I., Marković, B. D., Randjelović, D., Antić-Stanković, J., Božić, D., Cekić, N. D., Stevanović, V., Batinić, B., Aranđelović, J., Savić, M. M.,& Savić, S. D.. (2021). Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats. in International Journal of Molecular Sciences
MDPI., 22(15).
https://doi.org/10.3390/ijms22157991
Ðoković JB, Savić SM, Mitrović JR, Nikolić I, Marković BD, Randjelović D, Antić-Stanković J, Božić D, Cekić ND, Stevanović V, Batinić B, Aranđelović J, Savić MM, Savić SD. Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats. in International Journal of Molecular Sciences. 2021;22(15).
doi:10.3390/ijms22157991 .
Ðoković, Jelena B., Savić, Sanela M., Mitrović, Jelena R., Nikolić, Ines, Marković, Bojan D., Randjelović, Danijela, Antić-Stanković, Jelena, Božić, Dragana, Cekić, Nebojša D., Stevanović, Vladimir, Batinić, Bojan, Aranđelović, Jovana, Savić, Miroslav M., Savić, Snežana D., "Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats" in International Journal of Molecular Sciences, 22, no. 15 (2021),
https://doi.org/10.3390/ijms22157991 . .
22
21
21

Rapid detection of olive oil blends using a paper-based portable microfluidic platform

Radovanović, Milan; Ilić, Marko; Pastor, Kristian A.; Ačanski, Marijana M.; Panić, Sanja; Srdić, Vladimir V.; Randjelović, Danijela; Kojić, Tijana; Stojanović, Goran

(Elsevier, 2021)

TY  - JOUR
AU  - Radovanović, Milan
AU  - Ilić, Marko
AU  - Pastor, Kristian A.
AU  - Ačanski, Marijana M.
AU  - Panić, Sanja
AU  - Srdić, Vladimir V.
AU  - Randjelović, Danijela
AU  - Kojić, Tijana
AU  - Stojanović, Goran
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4236
AB  - This paper presents an application of a portable microfluidic platform based on a filter paper on which multi-walled carbon nanotubes were deposited to quickly determine the quality of olive oil by measuring electrical resistance. Three different types of filter paper with different pore sizes and different filtration rates were used in the middle of the microfluidic platform, as a material for soaking a blend of olive and high-oleic sunflower oil. The rapid prototyping xurographic technique was used to fabricate the complete microfluidic platform. For testing purposes, oil blends in various proportions were deposited through the inlet on the top of the platform. The variation in electrical resistance at room temperature was measured, using the Chemical Impedance Analyzer, successfully indicating oil proportions in measured blends. We obtained the change of resistance in the range from 0.26 MΩ to 2.79 MΩ per percentage of olive oil content, for corresponding linearity index from 0.71 to 0.99, for papers labelled with 44–45, respectively. Additionally, a prototype of electronic device was developed for acquisition and displaying measured data, based on the created microfluidic platform.
PB  - Elsevier
T2  - Food Control
T1  - Rapid detection of olive oil blends using a paper-based portable microfluidic platform
VL  - 124
SP  - 107888
DO  - 10.1016/j.foodcont.2021.107888
ER  - 
@article{
author = "Radovanović, Milan and Ilić, Marko and Pastor, Kristian A. and Ačanski, Marijana M. and Panić, Sanja and Srdić, Vladimir V. and Randjelović, Danijela and Kojić, Tijana and Stojanović, Goran",
year = "2021",
abstract = "This paper presents an application of a portable microfluidic platform based on a filter paper on which multi-walled carbon nanotubes were deposited to quickly determine the quality of olive oil by measuring electrical resistance. Three different types of filter paper with different pore sizes and different filtration rates were used in the middle of the microfluidic platform, as a material for soaking a blend of olive and high-oleic sunflower oil. The rapid prototyping xurographic technique was used to fabricate the complete microfluidic platform. For testing purposes, oil blends in various proportions were deposited through the inlet on the top of the platform. The variation in electrical resistance at room temperature was measured, using the Chemical Impedance Analyzer, successfully indicating oil proportions in measured blends. We obtained the change of resistance in the range from 0.26 MΩ to 2.79 MΩ per percentage of olive oil content, for corresponding linearity index from 0.71 to 0.99, for papers labelled with 44–45, respectively. Additionally, a prototype of electronic device was developed for acquisition and displaying measured data, based on the created microfluidic platform.",
publisher = "Elsevier",
journal = "Food Control",
title = "Rapid detection of olive oil blends using a paper-based portable microfluidic platform",
volume = "124",
pages = "107888",
doi = "10.1016/j.foodcont.2021.107888"
}
Radovanović, M., Ilić, M., Pastor, K. A., Ačanski, M. M., Panić, S., Srdić, V. V., Randjelović, D., Kojić, T.,& Stojanović, G.. (2021). Rapid detection of olive oil blends using a paper-based portable microfluidic platform. in Food Control
Elsevier., 124, 107888.
https://doi.org/10.1016/j.foodcont.2021.107888
Radovanović M, Ilić M, Pastor KA, Ačanski MM, Panić S, Srdić VV, Randjelović D, Kojić T, Stojanović G. Rapid detection of olive oil blends using a paper-based portable microfluidic platform. in Food Control. 2021;124:107888.
doi:10.1016/j.foodcont.2021.107888 .
Radovanović, Milan, Ilić, Marko, Pastor, Kristian A., Ačanski, Marijana M., Panić, Sanja, Srdić, Vladimir V., Randjelović, Danijela, Kojić, Tijana, Stojanović, Goran, "Rapid detection of olive oil blends using a paper-based portable microfluidic platform" in Food Control, 124 (2021):107888,
https://doi.org/10.1016/j.foodcont.2021.107888 . .
5
5
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