TY  - CONF
AU  - Pergal, Marija
AU  - Brkljačić, Jelena
AU  - Vasiljević-Radović, Dana
AU  - Pergal, Miodrag
AU  - Pešić, Ivan
AU  - Dević, Gordana
AU  - Tovilović-Kovačević, Gordana
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7359
AB  - Polyurethane (PU) nanocomposite materials, offer very desirable advantages over pure PU materials,as the nanocomposites have enhanced thermal, surface, mechanical and biological properties. The main goal of this study was to develop a new kind of novel nanocomposites consisting of crosslinked PUs (based on poly(dimetylsiloxane) and hyperbranched polyester) and ferrite nanoparticles (based on copper and zinc) for possible application as coatings on biomedical devices and implants. A series of PU/ferrite nanocomposites was prepared by in situ polymerization in solution. Characterization of prepared nanocomposites nanocomposites was conducted by Fourier transform infrared spectroscopy (FTIR) and atomic force microscopy (AFM). Copper and zinc releases were investigated by microwave plasma atomic emission spectrometry (MP-AES). Characteristics of the prepared nanocomposites when in contact with a biological environment were examined through testing their biocompatibility, and adhesion of fibroblast cells. The presence of the nanoferrite nanoparticles influenced on surface and biological properties of PU nanocomposites. The prepared PU nanocomposites with noncytotoxic chemistry could be used as promising materials for vascular implants development.
PB  - Belgrade: Serbian Ceramic Society
C3  - Program and the Book of Abstracts: Serbian Ceramic Society Conference Advanced Ceramics and Application 11: New Frontiers in Multifunctional Material Science and Processing; 2023 Sep 18-20; Belgrade, Serbia
T1  - Characterization of polyurethane/ferrite nanocomposites
SP  - 65
EP  - 65
UR  - https://hdl.handle.net/21.15107/rcub_cer_7359
ER  - 

@conference{
author = "Pergal, Marija and Brkljačić, Jelena and Vasiljević-Radović, Dana and Pergal, Miodrag and Pešić, Ivan and Dević, Gordana and Tovilović-Kovačević, Gordana",
year = "2023",
abstract = "Polyurethane (PU) nanocomposite materials, offer very desirable advantages over pure PU materials,as the nanocomposites have enhanced thermal, surface, mechanical and biological properties. The main goal of this study was to develop a new kind of novel nanocomposites consisting of crosslinked PUs (based on poly(dimetylsiloxane) and hyperbranched polyester) and ferrite nanoparticles (based on copper and zinc) for possible application as coatings on biomedical devices and implants. A series of PU/ferrite nanocomposites was prepared by in situ polymerization in solution. Characterization of prepared nanocomposites nanocomposites was conducted by Fourier transform infrared spectroscopy (FTIR) and atomic force microscopy (AFM). Copper and zinc releases were investigated by microwave plasma atomic emission spectrometry (MP-AES). Characteristics of the prepared nanocomposites when in contact with a biological environment were examined through testing their biocompatibility, and adhesion of fibroblast cells. The presence of the nanoferrite nanoparticles influenced on surface and biological properties of PU nanocomposites. The prepared PU nanocomposites with noncytotoxic chemistry could be used as promising materials for vascular implants development.",
publisher = "Belgrade: Serbian Ceramic Society",
journal = "Program and the Book of Abstracts: Serbian Ceramic Society Conference Advanced Ceramics and Application 11: New Frontiers in Multifunctional Material Science and Processing; 2023 Sep 18-20; Belgrade, Serbia",
title = "Characterization of polyurethane/ferrite nanocomposites",
pages = "65-65",
url = "https://hdl.handle.net/21.15107/rcub_cer_7359"
}

Pergal, M., Brkljačić, J., Vasiljević-Radović, D., Pergal, M., Pešić, I., Dević, G.,& Tovilović-Kovačević, G.. (2023). Characterization of polyurethane/ferrite nanocomposites. in Program and the Book of Abstracts: Serbian Ceramic Society Conference Advanced Ceramics and Application 11: New Frontiers in Multifunctional Material Science and Processing; 2023 Sep 18-20; Belgrade, Serbia
Belgrade: Serbian Ceramic Society., 65-65.
https://hdl.handle.net/21.15107/rcub_cer_7359

Pergal M, Brkljačić J, Vasiljević-Radović D, Pergal M, Pešić I, Dević G, Tovilović-Kovačević G. Characterization of polyurethane/ferrite nanocomposites. in Program and the Book of Abstracts: Serbian Ceramic Society Conference Advanced Ceramics and Application 11: New Frontiers in Multifunctional Material Science and Processing; 2023 Sep 18-20; Belgrade, Serbia. 2023;:65-65.
https://hdl.handle.net/21.15107/rcub_cer_7359 .

Pergal, Marija, Brkljačić, Jelena, Vasiljević-Radović, Dana, Pergal, Miodrag, Pešić, Ivan, Dević, Gordana, Tovilović-Kovačević, Gordana, "Characterization of polyurethane/ferrite nanocomposites" in Program and the Book of Abstracts: Serbian Ceramic Society Conference Advanced Ceramics and Application 11: New Frontiers in Multifunctional Material Science and Processing; 2023 Sep 18-20; Belgrade, Serbia (2023):65-65,
https://hdl.handle.net/21.15107/rcub_cer_7359 .

TY  - JOUR
AU  - Nikolić Kokić, Aleksandra
AU  - Tatalović, Nikola
AU  - Brkljačić, Jelena
AU  - Mijović, Milica
AU  - Nestorović, Vojkan
AU  - Mijušković, Ana
AU  - Oreščanin-Dušić, Zorana
AU  - Vidonja Uzelac, Teodora
AU  - Nikolić, Milan
AU  - Spasić, Snežana
AU  - Blagojević, Duško
AU  - Miljević, Čedo
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5557
AB  - Sexual dysfunction, as a noticeable adverse effect of atypical antipsychotic drugs (APDs)
for the treatment of schizophrenia, has not been investigated in detail. A study was undertaken
to investigate whether 28-day long treatment with clozapine, ziprasidone or sertindole (using a
recommended daily dose for atypical antipsychotic therapy), induced histopathological changes
both in rat testicles and prostate, changed the activity of the antioxidant defence system and altered blood testosterone and prolactin. Clozapine, ziprasidone and sertindole induced histopathological changes in rat testicular tissue, which could be attributed to a disturbed testicular antioxidant defence system in addition to an altered prolactin to testosterone ratio. None of the APD treatments induced histopathological changes in prostate. Our results demonstrate that APDs have the capacity to change both redox and endocrinological balance. One or both outcomes could underline testicular degeneration and disturbed spermatogenesis.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Antipsychotic Drug-Mediated Adverse Effects on Rat Testicles May Be Caused by Altered Redox and Hormonal Homeostasis
VL  - 23
IS  - 22
SP  - 13698
DO  - 10.3390/ijms232213698
ER  - 

@article{
author = "Nikolić Kokić, Aleksandra and Tatalović, Nikola and Brkljačić, Jelena and Mijović, Milica and Nestorović, Vojkan and Mijušković, Ana and Oreščanin-Dušić, Zorana and Vidonja Uzelac, Teodora and Nikolić, Milan and Spasić, Snežana and Blagojević, Duško and Miljević, Čedo",
year = "2022",
abstract = "Sexual dysfunction, as a noticeable adverse effect of atypical antipsychotic drugs (APDs)
for the treatment of schizophrenia, has not been investigated in detail. A study was undertaken
to investigate whether 28-day long treatment with clozapine, ziprasidone or sertindole (using a
recommended daily dose for atypical antipsychotic therapy), induced histopathological changes
both in rat testicles and prostate, changed the activity of the antioxidant defence system and altered blood testosterone and prolactin. Clozapine, ziprasidone and sertindole induced histopathological changes in rat testicular tissue, which could be attributed to a disturbed testicular antioxidant defence system in addition to an altered prolactin to testosterone ratio. None of the APD treatments induced histopathological changes in prostate. Our results demonstrate that APDs have the capacity to change both redox and endocrinological balance. One or both outcomes could underline testicular degeneration and disturbed spermatogenesis.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Antipsychotic Drug-Mediated Adverse Effects on Rat Testicles May Be Caused by Altered Redox and Hormonal Homeostasis",
volume = "23",
number = "22",
pages = "13698",
doi = "10.3390/ijms232213698"
}

Nikolić Kokić, A., Tatalović, N., Brkljačić, J., Mijović, M., Nestorović, V., Mijušković, A., Oreščanin-Dušić, Z., Vidonja Uzelac, T., Nikolić, M., Spasić, S., Blagojević, D.,& Miljević, Č.. (2022). Antipsychotic Drug-Mediated Adverse Effects on Rat Testicles May Be Caused by Altered Redox and Hormonal Homeostasis. in International Journal of Molecular Sciences
MDPI., 23(22), 13698.
https://doi.org/10.3390/ijms232213698

Nikolić Kokić A, Tatalović N, Brkljačić J, Mijović M, Nestorović V, Mijušković A, Oreščanin-Dušić Z, Vidonja Uzelac T, Nikolić M, Spasić S, Blagojević D, Miljević Č. Antipsychotic Drug-Mediated Adverse Effects on Rat Testicles May Be Caused by Altered Redox and Hormonal Homeostasis. in International Journal of Molecular Sciences. 2022;23(22):13698.
doi:10.3390/ijms232213698 .

Nikolić Kokić, Aleksandra, Tatalović, Nikola, Brkljačić, Jelena, Mijović, Milica, Nestorović, Vojkan, Mijušković, Ana, Oreščanin-Dušić, Zorana, Vidonja Uzelac, Teodora, Nikolić, Milan, Spasić, Snežana, Blagojević, Duško, Miljević, Čedo, "Antipsychotic Drug-Mediated Adverse Effects on Rat Testicles May Be Caused by Altered Redox and Hormonal Homeostasis" in International Journal of Molecular Sciences, 23, no. 22 (2022):13698,
https://doi.org/10.3390/ijms232213698 . .