TY  - JOUR
AU  - Avramov Ivić, Milka
AU  - Petrović, Slobodan D.
AU  - Živković, Predrag M.
AU  - Mijin, Dušan
AU  - Drljević, Katica M.
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/693
AB  - Using the cyclic voltammetry, it has been shown that hydrogen evolution at a gold electrode is necessary in the electrochemical activation of azithromycin dihydrate and erythromycin A. After four hours of the potential holding at -1.2 V vs. SCE, the pH of the electrolyte has been changed from 8.40 to 8.96; from 8.40 to 8.77 in the presence of erythromycin A, and from 8.40 to 9.18 in the presence of azithromycin, indicating the reaction of the hydrogen species with antibiotics. This effect has been confirmed by using the phenolphthalein indicator and by analysing colours of the solutions by UV-Vis, as well as by FTIR spectroscopy. Under the identical experimental conditions at the gold electrode, in contrast to azithromycin dihydrate and erythromycin A, roxithromycin and midecamycin electroactivity promotion has been obtained during the first forward sweep starting from the area of a double layer region.
AB  - Metodom ciklične voltametrije je pokazano da je izdvajanje vodonika na elektrodi od zlata neophodno za elektrohemijsku aktivaciju azitromicin-dihidrata i eritromicina A. Četiri sata držanja potencijala na vrednosti 1,2 V vs. SCE je rezultovalo u promeni pH elektrolita sa 8,40 na 8,96; sa 8,40 na 8,77 u prisustvu eritromicina A, i sa 8,40 na 9,18 u prisustvu azitromicina, ukazujući na reakciju čestica izdvojenog vodonika sa antibioticima. Efekat je potvrđen upotrebom fenolftalein indikatora i analizom boje elektrolita UV-Vis spektroskopijom, a molekula antibiotika FTIR spektroskopijom. Pod istim eksperimentalnim uslovima na elektrodi od zlata, u suprotnosti sa ponašanjem azitromicin-dihidrata i eritromicina A, elektroaktivnost roksitromicina i midekamicina je uočena počevši od oblasti formiranja dvojnog sloja, tj. bez ikakvog učešća čestica izdvojenog vodonika.
PB  - Association of the Chemical Engineers of Serbia
T2  - Chemical Industry and Chemical Engineering Quarterly / CICEQ
T1  - A study of the catalytic role of a gold electrode in the electrochemical activation of four macrolide antibiotics in sodium bicarbonate solution
T1  - Ispitivanje katalitičke uloge elektrode od zlata u elektrohemijskoj aktivaciji četiri makrolidna antibiotika u natrijum-bikarbonatnom elektrolitu
VL  - 16
IS  - 2
SP  - 111
EP  - 116
DO  - 10.2298/CICEQ091211017A
ER  - 

@article{
author = "Avramov Ivić, Milka and Petrović, Slobodan D. and Živković, Predrag M. and Mijin, Dušan and Drljević, Katica M.",
year = "2010",
abstract = "Using the cyclic voltammetry, it has been shown that hydrogen evolution at a gold electrode is necessary in the electrochemical activation of azithromycin dihydrate and erythromycin A. After four hours of the potential holding at -1.2 V vs. SCE, the pH of the electrolyte has been changed from 8.40 to 8.96; from 8.40 to 8.77 in the presence of erythromycin A, and from 8.40 to 9.18 in the presence of azithromycin, indicating the reaction of the hydrogen species with antibiotics. This effect has been confirmed by using the phenolphthalein indicator and by analysing colours of the solutions by UV-Vis, as well as by FTIR spectroscopy. Under the identical experimental conditions at the gold electrode, in contrast to azithromycin dihydrate and erythromycin A, roxithromycin and midecamycin electroactivity promotion has been obtained during the first forward sweep starting from the area of a double layer region., Metodom ciklične voltametrije je pokazano da je izdvajanje vodonika na elektrodi od zlata neophodno za elektrohemijsku aktivaciju azitromicin-dihidrata i eritromicina A. Četiri sata držanja potencijala na vrednosti 1,2 V vs. SCE je rezultovalo u promeni pH elektrolita sa 8,40 na 8,96; sa 8,40 na 8,77 u prisustvu eritromicina A, i sa 8,40 na 9,18 u prisustvu azitromicina, ukazujući na reakciju čestica izdvojenog vodonika sa antibioticima. Efekat je potvrđen upotrebom fenolftalein indikatora i analizom boje elektrolita UV-Vis spektroskopijom, a molekula antibiotika FTIR spektroskopijom. Pod istim eksperimentalnim uslovima na elektrodi od zlata, u suprotnosti sa ponašanjem azitromicin-dihidrata i eritromicina A, elektroaktivnost roksitromicina i midekamicina je uočena počevši od oblasti formiranja dvojnog sloja, tj. bez ikakvog učešća čestica izdvojenog vodonika.",
publisher = "Association of the Chemical Engineers of Serbia",
journal = "Chemical Industry and Chemical Engineering Quarterly / CICEQ",
title = "A study of the catalytic role of a gold electrode in the electrochemical activation of four macrolide antibiotics in sodium bicarbonate solution, Ispitivanje katalitičke uloge elektrode od zlata u elektrohemijskoj aktivaciji četiri makrolidna antibiotika u natrijum-bikarbonatnom elektrolitu",
volume = "16",
number = "2",
pages = "111-116",
doi = "10.2298/CICEQ091211017A"
}

Avramov Ivić, M., Petrović, S. D., Živković, P. M., Mijin, D.,& Drljević, K. M.. (2010). A study of the catalytic role of a gold electrode in the electrochemical activation of four macrolide antibiotics in sodium bicarbonate solution. in Chemical Industry and Chemical Engineering Quarterly / CICEQ
Association of the Chemical Engineers of Serbia., 16(2), 111-116.
https://doi.org/10.2298/CICEQ091211017A

Avramov Ivić M, Petrović SD, Živković PM, Mijin D, Drljević KM. A study of the catalytic role of a gold electrode in the electrochemical activation of four macrolide antibiotics in sodium bicarbonate solution. in Chemical Industry and Chemical Engineering Quarterly / CICEQ. 2010;16(2):111-116.
doi:10.2298/CICEQ091211017A .

Avramov Ivić, Milka, Petrović, Slobodan D., Živković, Predrag M., Mijin, Dušan, Drljević, Katica M., "A study of the catalytic role of a gold electrode in the electrochemical activation of four macrolide antibiotics in sodium bicarbonate solution" in Chemical Industry and Chemical Engineering Quarterly / CICEQ, 16, no. 2 (2010):111-116,
https://doi.org/10.2298/CICEQ091211017A . .

TY  - JOUR
AU  - Avramov Ivić, Milka
AU  - Petrović, Slobodan D.
AU  - Vonmoos, F.
AU  - Mijin, Dušan
AU  - Živković, Predrag M.
AU  - Drljević, Katica M.
PY  - 2007
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4256
AB  - The aim of the present study was the qualitative determination of the pure clarithromycin using a gold electrode in neutral electrolyte by cyclic linear sweep voltammetry. It was shown that in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, a gold electrode is successfully employed for the qualitative determination of clarithromycin by detection of the reproductive four anodic and one cathodic peaks. After the potentiostatic measurements at the potential values corresponded to current peaks, the bulk electrolyte was analyzed by FTIR spectroscopy to show the changes in molecular structure of clarithromycin. FTIR analysis of the bulk electrolyte after 4 h of holding the potential at -0.61 V vs. SCE (cathodic peak) showed the apparent changes in clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds.
PB  - Elsevier
T2  - Electrochemistry Communications
T1  - The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode
VL  - 9
IS  - 7
SP  - 1643
EP  - 1647
DO  - 10.1016/j.elecom.2007.03.011
ER  - 

@article{
author = "Avramov Ivić, Milka and Petrović, Slobodan D. and Vonmoos, F. and Mijin, Dušan and Živković, Predrag M. and Drljević, Katica M.",
year = "2007",
abstract = "The aim of the present study was the qualitative determination of the pure clarithromycin using a gold electrode in neutral electrolyte by cyclic linear sweep voltammetry. It was shown that in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, a gold electrode is successfully employed for the qualitative determination of clarithromycin by detection of the reproductive four anodic and one cathodic peaks. After the potentiostatic measurements at the potential values corresponded to current peaks, the bulk electrolyte was analyzed by FTIR spectroscopy to show the changes in molecular structure of clarithromycin. FTIR analysis of the bulk electrolyte after 4 h of holding the potential at -0.61 V vs. SCE (cathodic peak) showed the apparent changes in clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds.",
publisher = "Elsevier",
journal = "Electrochemistry Communications",
title = "The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode",
volume = "9",
number = "7",
pages = "1643-1647",
doi = "10.1016/j.elecom.2007.03.011"
}

Avramov Ivić, M., Petrović, S. D., Vonmoos, F., Mijin, D., Živković, P. M.,& Drljević, K. M.. (2007). The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode. in Electrochemistry Communications
Elsevier., 9(7), 1643-1647.
https://doi.org/10.1016/j.elecom.2007.03.011

Avramov Ivić M, Petrović SD, Vonmoos F, Mijin D, Živković PM, Drljević KM. The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode. in Electrochemistry Communications. 2007;9(7):1643-1647.
doi:10.1016/j.elecom.2007.03.011 .

Avramov Ivić, Milka, Petrović, Slobodan D., Vonmoos, F., Mijin, Dušan, Živković, Predrag M., Drljević, Katica M., "The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode" in Electrochemistry Communications, 9, no. 7 (2007):1643-1647,
https://doi.org/10.1016/j.elecom.2007.03.011 . .