Apostolski, S.

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  • Apostolski, S. (1)
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Content of NO reactive -SH and Superoxide dismutase activity in CSF of ALS patients

Marinković, Zorica; Nikolić, Aleksandra; Stojanović, Srđan; Blagojević, Duško; Niketić, Vesna; Radunović, A,; Apostolski, S.; Spasić, Mihajlo

(1997)

TY  - CONF
AU  - Marinković, Zorica
AU  - Nikolić, Aleksandra
AU  - Stojanović, Srđan
AU  - Blagojević, Duško
AU  - Niketić, Vesna
AU  - Radunović, A,
AU  - Apostolski, S.
AU  - Spasić, Mihajlo
PY  - 1997
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6540
AB  - The aim of this study was to investigate the content of -SU groups and SOD activity m cerebrospinal fluid (CSF) both in ALS patients and control group, as well as to perform an in vitro lest for CSF NO binding capacity, in same examines. Nitric oxide for in vitro testing was provided by adding 40% sodium nitrite solution in the solution of 10% ferrous sulfate in 50% sulfuric acid. Our results showed significant increase -SH content in CSF of ALS patients in comparison with control group (114 ± 29 nmol -SH/mg proteins in CSF of ALS patients compared with 37 ± 12 nmol - SI Lmg proteins in CSF of controls)(p<0.05). After in vitro saturation of CSF with NO, we noted (he significant decrease of -SH content which was not found in control group. We also found that SOD activity in CSF of ALS patients was higher than in control group (16.1 ±2.8 U7 mg CSF proteins of ALS patients compared to 10.2 ± 2 U/ mg CSF proteins of control group). These results may confirm an increased ROS production in ALS patients without increased NO production.
C3  - 8th International Symposium on ALS/MND, Glasgow
T1  - Content of NO reactive -SH and Superoxide dismutase activity in CSF of ALS patients
UR  - https://hdl.handle.net/21.15107/rcub_cer_6540
ER  - 
@conference{
author = "Marinković, Zorica and Nikolić, Aleksandra and Stojanović, Srđan and Blagojević, Duško and Niketić, Vesna and Radunović, A, and Apostolski, S. and Spasić, Mihajlo",
year = "1997",
abstract = "The aim of this study was to investigate the content of -SU groups and SOD activity m cerebrospinal fluid (CSF) both in ALS patients and control group, as well as to perform an in vitro lest for CSF NO binding capacity, in same examines. Nitric oxide for in vitro testing was provided by adding 40% sodium nitrite solution in the solution of 10% ferrous sulfate in 50% sulfuric acid. Our results showed significant increase -SH content in CSF of ALS patients in comparison with control group (114 ± 29 nmol -SH/mg proteins in CSF of ALS patients compared with 37 ± 12 nmol - SI Lmg proteins in CSF of controls)(p<0.05). After in vitro saturation of CSF with NO, we noted (he significant decrease of -SH content which was not found in control group. We also found that SOD activity in CSF of ALS patients was higher than in control group (16.1 ±2.8 U7 mg CSF proteins of ALS patients compared to 10.2 ± 2 U/ mg CSF proteins of control group). These results may confirm an increased ROS production in ALS patients without increased NO production.",
journal = "8th International Symposium on ALS/MND, Glasgow",
title = "Content of NO reactive -SH and Superoxide dismutase activity in CSF of ALS patients",
url = "https://hdl.handle.net/21.15107/rcub_cer_6540"
}
Marinković, Z., Nikolić, A., Stojanović, S., Blagojević, D., Niketić, V., Radunović, A., Apostolski, S.,& Spasić, M.. (1997). Content of NO reactive -SH and Superoxide dismutase activity in CSF of ALS patients. in 8th International Symposium on ALS/MND, Glasgow.
https://hdl.handle.net/21.15107/rcub_cer_6540
Marinković Z, Nikolić A, Stojanović S, Blagojević D, Niketić V, Radunović A, Apostolski S, Spasić M. Content of NO reactive -SH and Superoxide dismutase activity in CSF of ALS patients. in 8th International Symposium on ALS/MND, Glasgow. 1997;.
https://hdl.handle.net/21.15107/rcub_cer_6540 .
Marinković, Zorica, Nikolić, Aleksandra, Stojanović, Srđan, Blagojević, Duško, Niketić, Vesna, Radunović, A,, Apostolski, S., Spasić, Mihajlo, "Content of NO reactive -SH and Superoxide dismutase activity in CSF of ALS patients" in 8th International Symposium on ALS/MND, Glasgow (1997),
https://hdl.handle.net/21.15107/rcub_cer_6540 .