TY  - CONF
AU  - Lončarević, Branka
AU  - Joksimović, Kristina
AU  - Popović, Lazar
AU  - Avdalović, Jelena
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6427
AB  - Aktivnost mikroorganizama je direktno povezana sa njihovim disanjem. U prisustvu
velikih količina biodostupne organske supstance, brzina disanja mikroorganizama je veća.
Praćenje disanja je postalo bitan parametar u raznim procesima biodegradacije otpadne
supstance. Stoga, cilj ovog rada obuhvata praćenje ćelijskog disanja pomoću Micro-Oxymax
respirometra, kako bi se dobio bolji uvid u prisustvo dostupne organske supstance u
upotrebljenom rečnom sedimentu za generisanje električne energije pomoću MFC
PB  - Srpsko hemijsko društvo
C3  - Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023
T1  - Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta
T1  - Respiration of microorganisms in the MFC system during the generation of energy from river sediment
SP  - 169
EP  - 170
UR  - https://hdl.handle.net/21.15107/rcub_cer_6427
ER  - 

@conference{
author = "Lončarević, Branka and Joksimović, Kristina and Popović, Lazar and Avdalović, Jelena and Randjelović, Danijela and Beškoski, Vladimir",
year = "2023",
abstract = "Aktivnost mikroorganizama je direktno povezana sa njihovim disanjem. U prisustvu
velikih količina biodostupne organske supstance, brzina disanja mikroorganizama je veća.
Praćenje disanja je postalo bitan parametar u raznim procesima biodegradacije otpadne
supstance. Stoga, cilj ovog rada obuhvata praćenje ćelijskog disanja pomoću Micro-Oxymax
respirometra, kako bi se dobio bolji uvid u prisustvo dostupne organske supstance u
upotrebljenom rečnom sedimentu za generisanje električne energije pomoću MFC",
publisher = "Srpsko hemijsko društvo",
journal = "Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023",
title = "Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta, Respiration of microorganisms in the MFC system during the generation of energy from river sediment",
pages = "169-170",
url = "https://hdl.handle.net/21.15107/rcub_cer_6427"
}

Lončarević, B., Joksimović, K., Popović, L., Avdalović, J., Randjelović, D.,& Beškoski, V.. (2023). Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta. in Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023
Srpsko hemijsko društvo., 169-170.
https://hdl.handle.net/21.15107/rcub_cer_6427

Lončarević B, Joksimović K, Popović L, Avdalović J, Randjelović D, Beškoski V. Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta. in Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023. 2023;:169-170.
https://hdl.handle.net/21.15107/rcub_cer_6427 .

Lončarević, Branka, Joksimović, Kristina, Popović, Lazar, Avdalović, Jelena, Randjelović, Danijela, Beškoski, Vladimir, "Proces respiracije mikroorganizama u MFC sistemu tokom generisanja energije iz rečnog sedimenta" in Knjiga uzvoda - 9. Simpozijum Hemija i Zaštita Životne Sredine - EnviroChem2023, 4-7. jun 2023, Kladovo / Book of abstracts - 9 th Symposium Chemistry and Environmental Protection - EnviroChem2023, 4-7 th June 2023, Kladovo, Serbia, 2023 (2023):169-170,
https://hdl.handle.net/21.15107/rcub_cer_6427 .

TY  - CONF
AU  - Joksimović, Kristina
AU  - Žerađanin, Aleksandra
AU  - Lončarević, Branka
AU  - Lješević, Marija
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7117
AB  - The paramount challenge of the 21st century lies in the profound energy demands imposed by
contemporary society. The utilization of energy derived from non-renewable sources,
notably coal, oil, and their byproducts, is intrinsically associated with grave environmental
repercussions, primarily manifested in the form of pollution. The notion of fuel cells stands
as a prospective resolution to this problem, offering a sustainable avenue for energy
production devoid of environmentally adverse emissions. The aim of this research was to
explore the potential of carbon cloth electrodes in the Microbial Fuel Cell (MFC) system.
PB  - Institute of Technical Sciences of SASA
C3  - Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade
T1  - Utilization of carbon fiber in the context of microbial fuel cell systems
SP  - 70
EP  - 70
UR  - https://hdl.handle.net/21.15107/rcub_cer_7117
ER  - 

@conference{
author = "Joksimović, Kristina and Žerađanin, Aleksandra and Lončarević, Branka and Lješević, Marija and Randjelović, Danijela and Beškoski, Vladimir",
year = "2023",
abstract = "The paramount challenge of the 21st century lies in the profound energy demands imposed by
contemporary society. The utilization of energy derived from non-renewable sources,
notably coal, oil, and their byproducts, is intrinsically associated with grave environmental
repercussions, primarily manifested in the form of pollution. The notion of fuel cells stands
as a prospective resolution to this problem, offering a sustainable avenue for energy
production devoid of environmentally adverse emissions. The aim of this research was to
explore the potential of carbon cloth electrodes in the Microbial Fuel Cell (MFC) system.",
publisher = "Institute of Technical Sciences of SASA",
journal = "Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade",
title = "Utilization of carbon fiber in the context of microbial fuel cell systems",
pages = "70-70",
url = "https://hdl.handle.net/21.15107/rcub_cer_7117"
}

Joksimović, K., Žerađanin, A., Lončarević, B., Lješević, M., Randjelović, D.,& Beškoski, V.. (2023). Utilization of carbon fiber in the context of microbial fuel cell systems. in Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade
Institute of Technical Sciences of SASA., 70-70.
https://hdl.handle.net/21.15107/rcub_cer_7117

Joksimović K, Žerađanin A, Lončarević B, Lješević M, Randjelović D, Beškoski V. Utilization of carbon fiber in the context of microbial fuel cell systems. in Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade. 2023;:70-70.
https://hdl.handle.net/21.15107/rcub_cer_7117 .

Joksimović, Kristina, Žerađanin, Aleksandra, Lončarević, Branka, Lješević, Marija, Randjelović, Danijela, Beškoski, Vladimir, "Utilization of carbon fiber in the context of microbial fuel cell systems" in Programme and the Book of Abstracts -  Twenty-first Young Researchers’ Conference Materials Science and Engineering, November 29 - December 1, 2023, Belgrade (2023):70-70,
https://hdl.handle.net/21.15107/rcub_cer_7117 .

TY  - CONF
AU  - Joksimović, Kristina
AU  - Lješević, Marija
AU  - Lončarević, Branka
AU  - Žerađanin, Aleksandra
AU  - Kodranov, Igor
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7121
AB  - Microbial fuel cells (MFCs) are a promising technology that has the potential to solve environmental problems while simultaneously generating electricity. Thanks to the direct use of energy from the substrate and its conversion into electricity, as well as the controlled production of activated sludge, the multiplicity of independent applications highly qualifies MFC for the use of wastewater treatment. Wastewater from various industries is an ideal source of organic substrate that can potentially be used in MFC systems. In this way besides degrading organic pollutants, generated energy can be obtained as added value and used for various purposes.
PB  - Chemical Society of Montenegro
C3  - 23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro
T1  - Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration
SP  - 96
EP  - 96
UR  - https://hdl.handle.net/21.15107/rcub_cer_7121
ER  - 

@conference{
author = "Joksimović, Kristina and Lješević, Marija and Lončarević, Branka and Žerađanin, Aleksandra and Kodranov, Igor and Randjelović, Danijela and Beškoski, Vladimir",
year = "2023",
abstract = "Microbial fuel cells (MFCs) are a promising technology that has the potential to solve environmental problems while simultaneously generating electricity. Thanks to the direct use of energy from the substrate and its conversion into electricity, as well as the controlled production of activated sludge, the multiplicity of independent applications highly qualifies MFC for the use of wastewater treatment. Wastewater from various industries is an ideal source of organic substrate that can potentially be used in MFC systems. In this way besides degrading organic pollutants, generated energy can be obtained as added value and used for various purposes.",
publisher = "Chemical Society of Montenegro",
journal = "23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro",
title = "Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration",
pages = "96-96",
url = "https://hdl.handle.net/21.15107/rcub_cer_7121"
}

Joksimović, K., Lješević, M., Lončarević, B., Žerađanin, A., Kodranov, I., Randjelović, D.,& Beškoski, V.. (2023). Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration. in 23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro
Chemical Society of Montenegro., 96-96.
https://hdl.handle.net/21.15107/rcub_cer_7121

Joksimović K, Lješević M, Lončarević B, Žerađanin A, Kodranov I, Randjelović D, Beškoski V. Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration. in 23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro. 2023;:96-96.
https://hdl.handle.net/21.15107/rcub_cer_7121 .

Joksimović, Kristina, Lješević, Marija, Lončarević, Branka, Žerađanin, Aleksandra, Kodranov, Igor, Randjelović, Danijela, Beškoski, Vladimir, "Decolorization of Azo Dye Through the Utilization of Microbial Fuel Cells Connected in Parallel Confiouration" in 23rd European Meeting on Environmental Chemistry, EMEC23, Book of abstracts, December 3rd - December 6th, 2023, Budva, Montenegro (2023):96-96,
https://hdl.handle.net/21.15107/rcub_cer_7121 .

TY  - CONF
AU  - Bulatović, Sandra
AU  - Marković, Bojana
AU  - Tadić, Tamara
AU  - Nastasović, Aleksandra
AU  - Ilić, Mila
AU  - Randjelović, Danijela
AU  - Nedić, Natalija
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6692
AB  - Macroporous (glycidyl methacrylate) GMA-based composite was
synthesized via suspension polymerization in the presence of 2 wt. % magnetic
nanoparticles and functionalized with triethylenetetramine. Copper was immobilized
on composite by contacting modified copolymer with 0.1 M solution of CuCl2, at pH
5, and 25 ̊C. The obtained composite was characterized by mercury porosimetry,
Fourier transform infrared spectroscopy (FTIR) analysis and atomic force
microscopy (AFM). GMA-based composites, due to their properties (size, porosity,
etc.), and the presence of reactive epoxy group, have found a variety of applications
as sorbents, enzyme supports, in biomedical applications, for metal and organic
compounds sorption.1
The antimicrobial activity of the synthesized GMA/Cu copolymer against
Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger as
representatives for Gram-positive bacteria, Gram-negative bacteria, yeast and fungi
were investigated in this study.2 The copolymer displayed good antimicrobial activity
against all analyzed microbes, which makes it a material that can be potentially used
for biomedical (antibacterial and antifungal) applications.
PB  - Skopje : Society of chemists and technologists of Macedonia
C3  - Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia
T1  - Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer
SP  - 163
EP  - 163
UR  - https://hdl.handle.net/21.15107/rcub_cer_6692
ER  - 

@conference{
author = "Bulatović, Sandra and Marković, Bojana and Tadić, Tamara and Nastasović, Aleksandra and Ilić, Mila and Randjelović, Danijela and Nedić, Natalija",
year = "2023",
abstract = "Macroporous (glycidyl methacrylate) GMA-based composite was
synthesized via suspension polymerization in the presence of 2 wt. % magnetic
nanoparticles and functionalized with triethylenetetramine. Copper was immobilized
on composite by contacting modified copolymer with 0.1 M solution of CuCl2, at pH
5, and 25 ̊C. The obtained composite was characterized by mercury porosimetry,
Fourier transform infrared spectroscopy (FTIR) analysis and atomic force
microscopy (AFM). GMA-based composites, due to their properties (size, porosity,
etc.), and the presence of reactive epoxy group, have found a variety of applications
as sorbents, enzyme supports, in biomedical applications, for metal and organic
compounds sorption.1
The antimicrobial activity of the synthesized GMA/Cu copolymer against
Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger as
representatives for Gram-positive bacteria, Gram-negative bacteria, yeast and fungi
were investigated in this study.2 The copolymer displayed good antimicrobial activity
against all analyzed microbes, which makes it a material that can be potentially used
for biomedical (antibacterial and antifungal) applications.",
publisher = "Skopje : Society of chemists and technologists of Macedonia",
journal = "Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia",
title = "Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer",
pages = "163-163",
url = "https://hdl.handle.net/21.15107/rcub_cer_6692"
}

Bulatović, S., Marković, B., Tadić, T., Nastasović, A., Ilić, M., Randjelović, D.,& Nedić, N.. (2023). Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer. in Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia
Skopje : Society of chemists and technologists of Macedonia., 163-163.
https://hdl.handle.net/21.15107/rcub_cer_6692

Bulatović S, Marković B, Tadić T, Nastasović A, Ilić M, Randjelović D, Nedić N. Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer. in Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia. 2023;:163-163.
https://hdl.handle.net/21.15107/rcub_cer_6692 .

Bulatović, Sandra, Marković, Bojana, Tadić, Tamara, Nastasović, Aleksandra, Ilić, Mila, Randjelović, Danijela, Nedić, Natalija, "Determination of Antimicrobial Activity Of Copper Activated Macroporous GMA Based Copolymer" in Book of abstracts - 26th Congress of Chemists and Technologysts of Macedonia, 20–23 September 2023 Metropol Lake Resort Ohrid, N. Macedonia (2023):163-163,
https://hdl.handle.net/21.15107/rcub_cer_6692 .

TY  - JOUR
AU  - Stefanović, Ivan
AU  - Džunuzović, Jasna
AU  - Džunuzović, Enis
AU  - Randjelović, Danijela
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7192
AB  - The aim of this work was to examine the influence of polycaprolactone (PCL) as a soft segment (SS) on the surface properties of polyurethane networks (PUNs). Five PUNs with different SS content (from 10 to 50 wt%) were prepared using Boltorn® aliphatic hyperbranched polyester of the second pseudo generation and isophorone diisocyanate as components of hard segments. The structure, hydrophobicity, wettability, and swelling behavior of these PUNs were investigated. Primarily, the obtained results showed that properties of prepared PUNs strongly depend on the content of SS that is, PCL. It has been established that the increase of SS content reduced the degree of hydrogen bonding in PUNs. Also, the increase of the SS content in PUNs induced appearance of more pronounced microphase separated morphology, better hydrophobicity and non-wetting with diiodomethane. Simultaneously, the increase of the SS content led to the decrease of contact angles with formamide, and surface free energy of the prepared PUNs. These PUNs show good surface properties that are required for their potential application such as coatings.
PB  - John Wiley and Sons Inc.
T2  - Journal of Applied Polymer Science
T1  - The influence of polycaprolactone content on the surface properties of polyurethane networks
SP  - e54989
DO  - 10.1002/app.54989
ER  - 

@article{
author = "Stefanović, Ivan and Džunuzović, Jasna and Džunuzović, Enis and Randjelović, Danijela",
year = "2023",
abstract = "The aim of this work was to examine the influence of polycaprolactone (PCL) as a soft segment (SS) on the surface properties of polyurethane networks (PUNs). Five PUNs with different SS content (from 10 to 50 wt%) were prepared using Boltorn® aliphatic hyperbranched polyester of the second pseudo generation and isophorone diisocyanate as components of hard segments. The structure, hydrophobicity, wettability, and swelling behavior of these PUNs were investigated. Primarily, the obtained results showed that properties of prepared PUNs strongly depend on the content of SS that is, PCL. It has been established that the increase of SS content reduced the degree of hydrogen bonding in PUNs. Also, the increase of the SS content in PUNs induced appearance of more pronounced microphase separated morphology, better hydrophobicity and non-wetting with diiodomethane. Simultaneously, the increase of the SS content led to the decrease of contact angles with formamide, and surface free energy of the prepared PUNs. These PUNs show good surface properties that are required for their potential application such as coatings.",
publisher = "John Wiley and Sons Inc.",
journal = "Journal of Applied Polymer Science",
title = "The influence of polycaprolactone content on the surface properties of polyurethane networks",
pages = "e54989",
doi = "10.1002/app.54989"
}

Stefanović, I., Džunuzović, J., Džunuzović, E.,& Randjelović, D.. (2023). The influence of polycaprolactone content on the surface properties of polyurethane networks. in Journal of Applied Polymer Science
John Wiley and Sons Inc.., e54989.
https://doi.org/10.1002/app.54989

Stefanović I, Džunuzović J, Džunuzović E, Randjelović D. The influence of polycaprolactone content on the surface properties of polyurethane networks. in Journal of Applied Polymer Science. 2023;:e54989.
doi:10.1002/app.54989 .

Stefanović, Ivan, Džunuzović, Jasna, Džunuzović, Enis, Randjelović, Danijela, "The influence of polycaprolactone content on the surface properties of polyurethane networks" in Journal of Applied Polymer Science (2023):e54989,
https://doi.org/10.1002/app.54989 . .

TY  - JOUR
AU  - Mitrović, Jelena
AU  - Divović-Matović, Branka
AU  - Knutson, Daniel E.
AU  - Petković, Miloš
AU  - Đorović, Đordje
AU  - Randjelović, Danijela
AU  - Dobričić, Vladimir D.
AU  - Đoković, Jelena B.
AU  - Lunter, Dominique J.
AU  - Cook, James M.
AU  - Savić, Miroslav M.
AU  - Savić, Snežana D.
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5665
AB  - Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in water and oils. DK-I-60-3 (7-methoxy-d3-2-(4-methoxy-d3-phenyl)-2,5-dihydro-3Hpyrazolo[4,3-c]quinolin-3-one) is one of such pyrazoloquinolinones, and we recently reported about increased oral bioavailability of its nanocrystal formulation (NC). Lipid nanoparticles (LNP) with a high concentration of lecithin, which enhances loading capacity of the lipid matrix, may give rise to further improvement. After preformulation studies by differential scanning calorimetry and polarized light microscopy, LNP were prepared by the hot high pressure homogenization, and characterized in terms of particle size, morphology, and encapsulation efficacy. The layered structure visible on atomic force micrographs was confirmed by nuclear magnetic resonance. Obtained formulations were desirably stable, with small particle size (<100 nm), and high encapsulation efficacy (>99 %). Lecithin was partially fluid and most probably located in the outer shell of the particle, together with DK-I-60-3. While the hydrophobic part of polysorbate 80 was completely immobilized, its hydrophilic part was free in the aqueous phase. In oral neuropharmacokinetic study in rats, an around 1.5-fold increase of area under the curve with LNP compared to NC was noticed both in brain and plasma. In bioavailability study, F value of LNP (34.7 ± 12.4 %) was 1.4-fold higher than of NC (24.5 ± 7.8 %); however, this difference did not reach statistical significance. Therefore, employment of LNP platform in preclinical formulation of DK-I-60-3 imparted an incremental improvement of its physicochemical as well as pharmacokinetic behavior.
PB  - Elsevier B.V.
T2  - International Journal of Pharmaceutics
T1  - High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances
VL  - 633
SP  - 122613
DO  - 10.1016/j.ijpharm.2023.122613
ER  - 

@article{
author = "Mitrović, Jelena and Divović-Matović, Branka and Knutson, Daniel E. and Petković, Miloš and Đorović, Đordje and Randjelović, Danijela and Dobričić, Vladimir D. and Đoković, Jelena B. and Lunter, Dominique J. and Cook, James M. and Savić, Miroslav M. and Savić, Snežana D.",
year = "2023",
abstract = "Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in water and oils. DK-I-60-3 (7-methoxy-d3-2-(4-methoxy-d3-phenyl)-2,5-dihydro-3Hpyrazolo[4,3-c]quinolin-3-one) is one of such pyrazoloquinolinones, and we recently reported about increased oral bioavailability of its nanocrystal formulation (NC). Lipid nanoparticles (LNP) with a high concentration of lecithin, which enhances loading capacity of the lipid matrix, may give rise to further improvement. After preformulation studies by differential scanning calorimetry and polarized light microscopy, LNP were prepared by the hot high pressure homogenization, and characterized in terms of particle size, morphology, and encapsulation efficacy. The layered structure visible on atomic force micrographs was confirmed by nuclear magnetic resonance. Obtained formulations were desirably stable, with small particle size (<100 nm), and high encapsulation efficacy (>99 %). Lecithin was partially fluid and most probably located in the outer shell of the particle, together with DK-I-60-3. While the hydrophobic part of polysorbate 80 was completely immobilized, its hydrophilic part was free in the aqueous phase. In oral neuropharmacokinetic study in rats, an around 1.5-fold increase of area under the curve with LNP compared to NC was noticed both in brain and plasma. In bioavailability study, F value of LNP (34.7 ± 12.4 %) was 1.4-fold higher than of NC (24.5 ± 7.8 %); however, this difference did not reach statistical significance. Therefore, employment of LNP platform in preclinical formulation of DK-I-60-3 imparted an incremental improvement of its physicochemical as well as pharmacokinetic behavior.",
publisher = "Elsevier B.V.",
journal = "International Journal of Pharmaceutics",
title = "High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances",
volume = "633",
pages = "122613",
doi = "10.1016/j.ijpharm.2023.122613"
}

Mitrović, J., Divović-Matović, B., Knutson, D. E., Petković, M., Đorović, Đ., Randjelović, D., Dobričić, V. D., Đoković, J. B., Lunter, D. J., Cook, J. M., Savić, M. M.,& Savić, S. D.. (2023). High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances. in International Journal of Pharmaceutics
Elsevier B.V.., 633, 122613.
https://doi.org/10.1016/j.ijpharm.2023.122613

Mitrović J, Divović-Matović B, Knutson DE, Petković M, Đorović Đ, Randjelović D, Dobričić VD, Đoković JB, Lunter DJ, Cook JM, Savić MM, Savić SD. High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances. in International Journal of Pharmaceutics. 2023;633:122613.
doi:10.1016/j.ijpharm.2023.122613 .

Mitrović, Jelena, Divović-Matović, Branka, Knutson, Daniel E., Petković, Miloš, Đorović, Đordje, Randjelović, Danijela, Dobričić, Vladimir D., Đoković, Jelena B., Lunter, Dominique J., Cook, James M., Savić, Miroslav M., Savić, Snežana D., "High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances" in International Journal of Pharmaceutics, 633 (2023):122613,
https://doi.org/10.1016/j.ijpharm.2023.122613 . .

TY  - JOUR
AU  - Kašiković, Nemanja
AU  - Jurič, Ivana
AU  - Randjelović, Danijela
AU  - Spiridonov, Iskren
AU  - Żołek-Tryznowska, Zuzanna
AU  - Boeva, Rumyana
AU  - Petrović, Saša
PY  - 2023
UR  - https://hrcak.srce.hr/file/426027
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5868
AB  - Electrophotography is affected by several parameters, including printing machines and paper type, which determine the final quality of reproduction. For the
investigation of those effects, tests were done on the three types of electrophotography printing machines and eight types of uncoated paper with different properties of
weight, surface roughness, whiteness, brightness and opacity. Samples were printed with cyan, magenta, yellow and black toner under the standard, identical conditions.
The assessment of standard print quality parameter (optical density) was done using spectrodensitometer Techkon Spectro Dens. At the same time, the paper substrates
were characterized using the atomic force microscopy (AFM) as well as by spectrophotometric measurements (X Rite Eye-One, i1). Obtained results showed that the
reproducibility significantly depends on the type of printing machine rather than optical and mechanical properties of paper.
PB  - Osijek : Sveučilište Josipa Jurja Strossmayera
PB  - Slavonski brod : Strojarski Fakultet
T2  - Technical Gazette (Tehnički vjesnik)
T1  - Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography
VL  - 30
IS  - 2
SP  - 481
EP  - 485
DO  - 10.17559/TV-20220725151112
ER  - 

@article{
author = "Kašiković, Nemanja and Jurič, Ivana and Randjelović, Danijela and Spiridonov, Iskren and Żołek-Tryznowska, Zuzanna and Boeva, Rumyana and Petrović, Saša",
year = "2023",
abstract = "Electrophotography is affected by several parameters, including printing machines and paper type, which determine the final quality of reproduction. For the
investigation of those effects, tests were done on the three types of electrophotography printing machines and eight types of uncoated paper with different properties of
weight, surface roughness, whiteness, brightness and opacity. Samples were printed with cyan, magenta, yellow and black toner under the standard, identical conditions.
The assessment of standard print quality parameter (optical density) was done using spectrodensitometer Techkon Spectro Dens. At the same time, the paper substrates
were characterized using the atomic force microscopy (AFM) as well as by spectrophotometric measurements (X Rite Eye-One, i1). Obtained results showed that the
reproducibility significantly depends on the type of printing machine rather than optical and mechanical properties of paper.",
publisher = "Osijek : Sveučilište Josipa Jurja Strossmayera, Slavonski brod : Strojarski Fakultet",
journal = "Technical Gazette (Tehnički vjesnik)",
title = "Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography",
volume = "30",
number = "2",
pages = "481-485",
doi = "10.17559/TV-20220725151112"
}

Kašiković, N., Jurič, I., Randjelović, D., Spiridonov, I., Żołek-Tryznowska, Z., Boeva, R.,& Petrović, S.. (2023). Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography. in Technical Gazette (Tehnički vjesnik)
Osijek : Sveučilište Josipa Jurja Strossmayera., 30(2), 481-485.
https://doi.org/10.17559/TV-20220725151112

Kašiković N, Jurič I, Randjelović D, Spiridonov I, Żołek-Tryznowska Z, Boeva R, Petrović S. Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography. in Technical Gazette (Tehnički vjesnik). 2023;30(2):481-485.
doi:10.17559/TV-20220725151112 .

Kašiković, Nemanja, Jurič, Ivana, Randjelović, Danijela, Spiridonov, Iskren, Żołek-Tryznowska, Zuzanna, Boeva, Rumyana, Petrović, Saša, "Influence of Paper Properties and Printing Machines Properties on Optical Density in Electrophotography" in Technical Gazette (Tehnički vjesnik), 30, no. 2 (2023):481-485,
https://doi.org/10.17559/TV-20220725151112 . .

TY  - CONF
AU  - Nikolić, Ines
AU  - Petrović, Marija
AU  - Krupnik, Leondard
AU  - Randjelović, Danijela
AU  - Avaro, Jonathan
AU  - Neels, Antonia
AU  - Borchard, Gerrit
AU  - Jordan, Olivier
AU  - Đoković, Jelena
AU  - Savić, Snežana
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6419
AB  - The aim of the presented research was to perform a thorough analysis of the selected nanosystem (nanoemulsion) focusing on size estimation and particle-protein interaction applying several state-of-the art techniques, highlighting important factors for a reliable analysis.
T1  - Sizing experiments and bio-nano interactions: method matters
UR  - https://hdl.handle.net/21.15107/rcub_cer_6419
ER  - 

@conference{
author = "Nikolić, Ines and Petrović, Marija and Krupnik, Leondard and Randjelović, Danijela and Avaro, Jonathan and Neels, Antonia and Borchard, Gerrit and Jordan, Olivier and Đoković, Jelena and Savić, Snežana",
year = "2023",
abstract = "The aim of the presented research was to perform a thorough analysis of the selected nanosystem (nanoemulsion) focusing on size estimation and particle-protein interaction applying several state-of-the art techniques, highlighting important factors for a reliable analysis.",
title = "Sizing experiments and bio-nano interactions: method matters",
url = "https://hdl.handle.net/21.15107/rcub_cer_6419"
}

Nikolić, I., Petrović, M., Krupnik, L., Randjelović, D., Avaro, J., Neels, A., Borchard, G., Jordan, O., Đoković, J.,& Savić, S.. (2023). Sizing experiments and bio-nano interactions: method matters. .
https://hdl.handle.net/21.15107/rcub_cer_6419

Nikolić I, Petrović M, Krupnik L, Randjelović D, Avaro J, Neels A, Borchard G, Jordan O, Đoković J, Savić S. Sizing experiments and bio-nano interactions: method matters. 2023;.
https://hdl.handle.net/21.15107/rcub_cer_6419 .

Nikolić, Ines, Petrović, Marija, Krupnik, Leondard, Randjelović, Danijela, Avaro, Jonathan, Neels, Antonia, Borchard, Gerrit, Jordan, Olivier, Đoković, Jelena, Savić, Snežana, "Sizing experiments and bio-nano interactions: method matters" (2023),
https://hdl.handle.net/21.15107/rcub_cer_6419 .

TY  - CONF
AU  - Lončarević, Branka
AU  - Nikolić, Vladimir
AU  - Randjelović, Danijela
AU  - Poljak, Predrag
AU  - Gojgić-Cvijović, Gordana
AU  - Beškoski, Vladimir
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5720
AB  - Food packaging ensures safety and hygiene, while reducing food waste, therefore it is and ssential component of the food supply chain. A sustainable and biodegradable alternative to conventional food packaging is edible packaging which contributes to the reducing waste and the economic efficiency of packaging materials. The numerous biopolymeric materials could be used as source such as polysaccharides (starch, cellulose, chitosan) and proteins (gelatin, soy protein, whey). Exopolysaccharides (EPS) are fermentation-based biopolyrners, secreted outside the cell wall and synthesized by various microbial species including bacteria, fungi and blue-green algae. Microbial levan is fructose-based EPS and convenient due to its biocornpatibility, renewability, high molecular weight, low viscous nature, antioxidant and prebiotic effects. Levan used in this work was produced by the B. licheniformis NS032 strain and its hydrophobic derivatives were obtained using octenyl succinic anhydride (OSA). Degree of substitution (DS) for modified levans were 0.025 and 0.032 for LH22 and LH25 respectively. Three different film compositions were prepared: 
levan/LH22/LH26 with gelatin in proportions 1:1. Films were prepared by casting technique and evaporated at room temperature. Morphology of the obtained films were studied by ARV (Atomic force microscopy), AutoProbe CP-Research SPM (TM Microscopes-Broker) and mechanical properties were examined by Shimodzu E2-LX tensile tester. The samples had thickness of 150 trrrl. Based on morphological measurements, it can be concluded that use of levan derivatives change roughness of the levan/gelatin blend film. The best mechanical properties (tensile strength and elongation at break) were obtained with pure levan. Obtained films are composed from edible and biodegradable components and therefore are potentially applicable in food industry. Future investigation will be focused on optimization of levan/gelatin proportion and more extensive 
structural and mechanical properties of obtained films.
PB  - COST Action 19124
PB  - Ljubljana, Slovenia : Pulp and Paper Institute
C3  - Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana
T1  - Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin
SP  - 109
EP  - 110
UR  - https://hdl.handle.net/21.15107/rcub_cer_5720
ER  - 

@conference{
author = "Lončarević, Branka and Nikolić, Vladimir and Randjelović, Danijela and Poljak, Predrag and Gojgić-Cvijović, Gordana and Beškoski, Vladimir",
year = "2022",
abstract = "Food packaging ensures safety and hygiene, while reducing food waste, therefore it is and ssential component of the food supply chain. A sustainable and biodegradable alternative to conventional food packaging is edible packaging which contributes to the reducing waste and the economic efficiency of packaging materials. The numerous biopolymeric materials could be used as source such as polysaccharides (starch, cellulose, chitosan) and proteins (gelatin, soy protein, whey). Exopolysaccharides (EPS) are fermentation-based biopolyrners, secreted outside the cell wall and synthesized by various microbial species including bacteria, fungi and blue-green algae. Microbial levan is fructose-based EPS and convenient due to its biocornpatibility, renewability, high molecular weight, low viscous nature, antioxidant and prebiotic effects. Levan used in this work was produced by the B. licheniformis NS032 strain and its hydrophobic derivatives were obtained using octenyl succinic anhydride (OSA). Degree of substitution (DS) for modified levans were 0.025 and 0.032 for LH22 and LH25 respectively. Three different film compositions were prepared: 
levan/LH22/LH26 with gelatin in proportions 1:1. Films were prepared by casting technique and evaporated at room temperature. Morphology of the obtained films were studied by ARV (Atomic force microscopy), AutoProbe CP-Research SPM (TM Microscopes-Broker) and mechanical properties were examined by Shimodzu E2-LX tensile tester. The samples had thickness of 150 trrrl. Based on morphological measurements, it can be concluded that use of levan derivatives change roughness of the levan/gelatin blend film. The best mechanical properties (tensile strength and elongation at break) were obtained with pure levan. Obtained films are composed from edible and biodegradable components and therefore are potentially applicable in food industry. Future investigation will be focused on optimization of levan/gelatin proportion and more extensive 
structural and mechanical properties of obtained films.",
publisher = "COST Action 19124, Ljubljana, Slovenia : Pulp and Paper Institute",
journal = "Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana",
title = "Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin",
pages = "109-110",
url = "https://hdl.handle.net/21.15107/rcub_cer_5720"
}

Lončarević, B., Nikolić, V., Randjelović, D., Poljak, P., Gojgić-Cvijović, G.,& Beškoski, V.. (2022). Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin. in Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana
COST Action 19124., 109-110.
https://hdl.handle.net/21.15107/rcub_cer_5720

Lončarević B, Nikolić V, Randjelović D, Poljak P, Gojgić-Cvijović G, Beškoski V. Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin. in Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana. 2022;:109-110.
https://hdl.handle.net/21.15107/rcub_cer_5720 .

Lončarević, Branka, Nikolić, Vladimir, Randjelović, Danijela, Poljak, Predrag, Gojgić-Cvijović, Gordana, Beškoski, Vladimir, "Characterisation of Blend Film Based on Microbial Polysaccharide Levan and Gelatin" in Book of Abstracts - 2nd CIRCUL-A-BILITY Conference, September 12-14, 2022, Ljubljana (2022):109-110,
https://hdl.handle.net/21.15107/rcub_cer_5720 .

TY  - CONF
AU  - Randjelović, Danijela
AU  - Joksimović, Kristina
AU  - Kodranov, Igor
AU  - Žerađanin, Aleksandra
AU  - Popović, Bogdan
AU  - Poljak, Predrag
AU  - Manojlović, Dragan
AU  - Beškoski, Vladimir
PY  - 2022
UR  - https://ieeexplore.ieee.org/document/9934706
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5857
AB  - This paper gives overview of research activities, performed by our team, in the field of Microbial Fuel Cells (MFCs). Evolution of construction, performance and application of MFCs is presented. The path towards optimization of the performance led through design and construction of the cell and was followed by investigation of impact of different sediments containing different microbial communities. The sediment samples were collected from two locations in Serbia, confluence of rivers Sava and Danube in Belgrade and the acid mine drainage lake "Robule" in the copper mine Bor. Results of verified application in wastewater treatment are discussed.
PB  - Institute of Electrical and Electronics Engineers Inc (IEEE)
C3  - Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania
T1  - Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments
SP  - 30
EP  - 37
DO  - 10.1109/CAS56377.2022.9934706
ER  - 

@conference{
author = "Randjelović, Danijela and Joksimović, Kristina and Kodranov, Igor and Žerađanin, Aleksandra and Popović, Bogdan and Poljak, Predrag and Manojlović, Dragan and Beškoski, Vladimir",
year = "2022",
abstract = "This paper gives overview of research activities, performed by our team, in the field of Microbial Fuel Cells (MFCs). Evolution of construction, performance and application of MFCs is presented. The path towards optimization of the performance led through design and construction of the cell and was followed by investigation of impact of different sediments containing different microbial communities. The sediment samples were collected from two locations in Serbia, confluence of rivers Sava and Danube in Belgrade and the acid mine drainage lake "Robule" in the copper mine Bor. Results of verified application in wastewater treatment are discussed.",
publisher = "Institute of Electrical and Electronics Engineers Inc (IEEE)",
journal = "Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania",
title = "Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments",
pages = "30-37",
doi = "10.1109/CAS56377.2022.9934706"
}

Randjelović, D., Joksimović, K., Kodranov, I., Žerađanin, A., Popović, B., Poljak, P., Manojlović, D.,& Beškoski, V.. (2022). Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments. in Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania
Institute of Electrical and Electronics Engineers Inc (IEEE)., 30-37.
https://doi.org/10.1109/CAS56377.2022.9934706

Randjelović D, Joksimović K, Kodranov I, Žerađanin A, Popović B, Poljak P, Manojlović D, Beškoski V. Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments. in Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania. 2022;:30-37.
doi:10.1109/CAS56377.2022.9934706 .

Randjelović, Danijela, Joksimović, Kristina, Kodranov, Igor, Žerađanin, Aleksandra, Popović, Bogdan, Poljak, Predrag, Manojlović, Dragan, Beškoski, Vladimir, "Evolution of Construction, Performance and Application of Microbial Fuel Cells Based on River and Acid Mine Drainage Sediments" in Proceedings - 45th IEEE International Semiconductor Conference CAS 2022, Poiana Brasov, October 12-14, 2022, Romania (2022):30-37,
https://doi.org/10.1109/CAS56377.2022.9934706 . .

TY  - JOUR
AU  - Joksimović, Kristina
AU  - Kodranov, Igor
AU  - Randjelović, Danijela
AU  - Slavković Beškoski, Latinka
AU  - Radulović, Jelena
AU  - Lješević, Marija
AU  - Manojlović, Dragan
AU  - Beškoski, Vladimir
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4942
AB  - The problem of wastewater has long been ubiquitous and has great consequences for the environment and its
inhabitants. Microbial fuel cells (MFCs) have enormous potential for the treatment of wastewaters polluted with
azo dyes. The amount of energy that can be produced from a single-chamber MFC is sufficient to perform
decolorization and degradation of such dyes, which are widely used in the textile industry. This study on the azo
dye, reactive black 5 (RB5), provides an alternative method through three parallel-connected MFCs to obtain
electricity that directly serves for the dye’s electrochemical degradation. We examined degradation followed by
decolorization of RB5 using Fe and Pt electrodes, together with H2O2, to achieve the electro-Fenton process. The
amount of voltage produced (295 mV), the current density (276 mA m− 3
) and the power density (50 mW m− 3
)
were sufficient to degrade 25 mg L-1 RB5 dye with 0.5 mM H2O2 in just 2 h. The dye degradation mechanism was
investigated using UV–VIS, FT-IR and HPLC-MS/MS. The ecotoxicity of the degradation products was assessed
using a bacterial model, Aliivibrio fischeri. These tests showed that there was successful degradation of the dye to
products whose toxicity is less than that of RB5.
PB  - Elsevier
T2  - Bioelectrochemistry
T1  - Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye
VL  - 145
SP  - 108088
DO  - 10.1016/j.bioelechem.2022.108088
ER  - 

@article{
author = "Joksimović, Kristina and Kodranov, Igor and Randjelović, Danijela and Slavković Beškoski, Latinka and Radulović, Jelena and Lješević, Marija and Manojlović, Dragan and Beškoski, Vladimir",
year = "2022",
abstract = "The problem of wastewater has long been ubiquitous and has great consequences for the environment and its
inhabitants. Microbial fuel cells (MFCs) have enormous potential for the treatment of wastewaters polluted with
azo dyes. The amount of energy that can be produced from a single-chamber MFC is sufficient to perform
decolorization and degradation of such dyes, which are widely used in the textile industry. This study on the azo
dye, reactive black 5 (RB5), provides an alternative method through three parallel-connected MFCs to obtain
electricity that directly serves for the dye’s electrochemical degradation. We examined degradation followed by
decolorization of RB5 using Fe and Pt electrodes, together with H2O2, to achieve the electro-Fenton process. The
amount of voltage produced (295 mV), the current density (276 mA m− 3
) and the power density (50 mW m− 3
)
were sufficient to degrade 25 mg L-1 RB5 dye with 0.5 mM H2O2 in just 2 h. The dye degradation mechanism was
investigated using UV–VIS, FT-IR and HPLC-MS/MS. The ecotoxicity of the degradation products was assessed
using a bacterial model, Aliivibrio fischeri. These tests showed that there was successful degradation of the dye to
products whose toxicity is less than that of RB5.",
publisher = "Elsevier",
journal = "Bioelectrochemistry",
title = "Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye",
volume = "145",
pages = "108088",
doi = "10.1016/j.bioelechem.2022.108088"
}

Joksimović, K., Kodranov, I., Randjelović, D., Slavković Beškoski, L., Radulović, J., Lješević, M., Manojlović, D.,& Beškoski, V.. (2022). Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye. in Bioelectrochemistry
Elsevier., 145, 108088.
https://doi.org/10.1016/j.bioelechem.2022.108088

Joksimović K, Kodranov I, Randjelović D, Slavković Beškoski L, Radulović J, Lješević M, Manojlović D, Beškoski V. Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye. in Bioelectrochemistry. 2022;145:108088.
doi:10.1016/j.bioelechem.2022.108088 .

Joksimović, Kristina, Kodranov, Igor, Randjelović, Danijela, Slavković Beškoski, Latinka, Radulović, Jelena, Lješević, Marija, Manojlović, Dragan, Beškoski, Vladimir, "Microbial fuel cells as an electrical energy source for degradation followed by decolorization of Reactive Black 5 azo dye" in Bioelectrochemistry, 145 (2022):108088,
https://doi.org/10.1016/j.bioelechem.2022.108088 . .

TY  - JOUR
AU  - Timotijević, Mirjana
AU  - Ilić, Tanja
AU  - Marković, Bojan
AU  - Randjelović, Danijela
AU  - Cekić, Nebojša
AU  - Nikolić, Ines
AU  - Savić, Snežana
AU  - Pantelić, Ivana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5258
AB  - Polymeric film-forming systems have emerged as an esthetically acceptable option for targeted, less frequent and controlled dermal drug delivery. However, their dynamic nature (rapid evaporation of solvents leading to the formation of thin films) presents a true characterization chal- lenge. In this study, we tested a tiered characterization approach, leading to more efficient definition of the quality target product profiles of film-forming systems. After assessing a number of physico- chemico-mechanical properties, thermal, spectroscopic and microscopic techniques were introduced. Final confirmation of betamethasone dipropionate-loaded FFS biopharmaceutical properties was sought via an in vitro skin permeation study. A number of applied characterization methods showed complementarity. The sample based on a combination of hydrophobic Eudragit® RS PO and hy- droxypropyl cellulose showed higher viscosity (47.17 ± 3.06 mPa·s) and film thickness, resulting in sustained skin permeation (permeation rate of 0.348 ± 0.157 ng/cm2 h), and even the pH of the sample with Eudragit® NE 30D, along with higher surface roughness and thermal analysis, implied its immediate delivery through the epidermal membrane. Therefore, this study revealed the utility of several methods able to refine the number of needed tests within the final product profile.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study
VL  - 23
IS  - 11
DO  - 10.3390/ijms23116013
ER  - 

@article{
author = "Timotijević, Mirjana and Ilić, Tanja and Marković, Bojan and Randjelović, Danijela and Cekić, Nebojša and Nikolić, Ines and Savić, Snežana and Pantelić, Ivana",
year = "2022",
abstract = "Polymeric film-forming systems have emerged as an esthetically acceptable option for targeted, less frequent and controlled dermal drug delivery. However, their dynamic nature (rapid evaporation of solvents leading to the formation of thin films) presents a true characterization chal- lenge. In this study, we tested a tiered characterization approach, leading to more efficient definition of the quality target product profiles of film-forming systems. After assessing a number of physico- chemico-mechanical properties, thermal, spectroscopic and microscopic techniques were introduced. Final confirmation of betamethasone dipropionate-loaded FFS biopharmaceutical properties was sought via an in vitro skin permeation study. A number of applied characterization methods showed complementarity. The sample based on a combination of hydrophobic Eudragit® RS PO and hy- droxypropyl cellulose showed higher viscosity (47.17 ± 3.06 mPa·s) and film thickness, resulting in sustained skin permeation (permeation rate of 0.348 ± 0.157 ng/cm2 h), and even the pH of the sample with Eudragit® NE 30D, along with higher surface roughness and thermal analysis, implied its immediate delivery through the epidermal membrane. Therefore, this study revealed the utility of several methods able to refine the number of needed tests within the final product profile.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study",
volume = "23",
number = "11",
doi = "10.3390/ijms23116013"
}

Timotijević, M., Ilić, T., Marković, B., Randjelović, D., Cekić, N., Nikolić, I., Savić, S.,& Pantelić, I.. (2022). Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study. in International Journal of Molecular Sciences
MDPI., 23(11).
https://doi.org/10.3390/ijms23116013

Timotijević M, Ilić T, Marković B, Randjelović D, Cekić N, Nikolić I, Savić S, Pantelić I. Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study. in International Journal of Molecular Sciences. 2022;23(11).
doi:10.3390/ijms23116013 .

Timotijević, Mirjana, Ilić, Tanja, Marković, Bojan, Randjelović, Danijela, Cekić, Nebojša, Nikolić, Ines, Savić, Snežana, Pantelić, Ivana, "Coupling AFM, DSC and FT-IR towards Elucidation of Film-Forming Systems Transformation to Dermal Films: A Betamethasone Dipropionate Case Study" in International Journal of Molecular Sciences, 23, no. 11 (2022),
https://doi.org/10.3390/ijms23116013 . .

TY  - CONF
AU  - Mitrović, Jelena
AU  - Petković, Miloš
AU  - Randjelović, Danijela
AU  - Đoković, Jelena
AU  - Knutson, Daniel
AU  - Cook, James
AU  - Savić, Vladimir
AU  - Savić, Miroslav
AU  - Savić, Snežana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5259
AB  - Poster presented at 13th World meeting on pharmaceutics, biopharmaceutics and pharmaceutical technology, 28-31 March 2022, Rotterdam, Netherlands
T1  - Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3
UR  - https://hdl.handle.net/21.15107/rcub_cer_5259
ER  - 

@conference{
author = "Mitrović, Jelena and Petković, Miloš and Randjelović, Danijela and Đoković, Jelena and Knutson, Daniel and Cook, James and Savić, Vladimir and Savić, Miroslav and Savić, Snežana",
year = "2022",
abstract = "Poster presented at 13th World meeting on pharmaceutics, biopharmaceutics and pharmaceutical technology, 28-31 March 2022, Rotterdam, Netherlands",
title = "Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3",
url = "https://hdl.handle.net/21.15107/rcub_cer_5259"
}

Mitrović, J., Petković, M., Randjelović, D., Đoković, J., Knutson, D., Cook, J., Savić, V., Savić, M.,& Savić, S.. (2022). Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3. .
https://hdl.handle.net/21.15107/rcub_cer_5259

Mitrović J, Petković M, Randjelović D, Đoković J, Knutson D, Cook J, Savić V, Savić M, Savić S. Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3. 2022;.
https://hdl.handle.net/21.15107/rcub_cer_5259 .

Mitrović, Jelena, Petković, Miloš, Randjelović, Danijela, Đoković, Jelena, Knutson, Daniel, Cook, James, Savić, Vladimir, Savić, Miroslav, Savić, Snežana, "Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3" (2022),
https://hdl.handle.net/21.15107/rcub_cer_5259 .

TY  - JOUR
AU  - Đoković, Jelena B.
AU  - Demisli, Sotiria
AU  - Savić, Sanela M.
AU  - Marković, Bojan D.
AU  - Cekić, Nebojša D.
AU  - Randjelović, Danijela
AU  - Mitrović, Jelena R.
AU  - Lunter, Dominique Jasmin
AU  - Papadimitriou, Vassiliki
AU  - Xenakis, Aristotelis
AU  - Savić, Snežana D.
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5375
AB  - A nanotechnology-based approach to drug delivery presents one of the biggest trends in biomedical science that can provide increased active concentration, bioavailability, and safety compared to conventional drug-delivery systems. Nanoemulsions stand out amongst other nanocarriers for being biodegradable, biocompatible, and relatively easy to manufacture. For improved drug-delivery properties, longer circulation for the nanoemulsion droplets should be provided, to allow the active to reach the target site. One of the strategies used for this purpose is PEGylation. The aim of this research was assessing the impact of the oil phase selection, soybean or fish oil mixtures with medium chain triglycerides, on the physicochemical characteristics and injectability of curcumin-loaded PEGylated nanoemulsions. Electron paramagnetic resonance spectroscopy demonstrated the structural impact of the oil phase on the stabilizing layer of nanoemulsions, with a more pronounced stabilizing effect of curcumin observed in the fish oil nanoemulsion compared to the soybean oil one. The design of the experiment study, employed to simultaneously assess the impact of the oil phase, different PEGylated phospholipids and their concentrations, as well as the presence of curcumin, showed that not only the investigated factors alone, but also their interactions, had a significant influence on the critical quality attributes of the PEGylated nanoemulsions. Detailed physicochemical characterization of the NEs found all formulations were appropriate for parenteral administration and remained stable during two years of storage, with the preserved antioxidant activity demonstrated by DPPH and FRAP assays. In vitro release studies showed a more pronounced release of curcumin from the fish oil NEs compared to that from the soybean oil ones. The innovative in vitro injectability assessment, designed to mimic intravenous application, proved that all formulations tested in selected experimental setting could be employed in prospective in vivo studies. Overall, the current study shows the importance of oil phase selection when formulating PEGylated nanoemulsions.
PB  - Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)
T2  - Pharmaceutics
T1  - The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions
VL  - 14
IS  - 8
SP  - 1666
DO  - 10.3390/pharmaceutics14081666
ER  - 

@article{
author = "Đoković, Jelena B. and Demisli, Sotiria and Savić, Sanela M. and Marković, Bojan D. and Cekić, Nebojša D. and Randjelović, Danijela and Mitrović, Jelena R. and Lunter, Dominique Jasmin and Papadimitriou, Vassiliki and Xenakis, Aristotelis and Savić, Snežana D.",
year = "2022",
abstract = "A nanotechnology-based approach to drug delivery presents one of the biggest trends in biomedical science that can provide increased active concentration, bioavailability, and safety compared to conventional drug-delivery systems. Nanoemulsions stand out amongst other nanocarriers for being biodegradable, biocompatible, and relatively easy to manufacture. For improved drug-delivery properties, longer circulation for the nanoemulsion droplets should be provided, to allow the active to reach the target site. One of the strategies used for this purpose is PEGylation. The aim of this research was assessing the impact of the oil phase selection, soybean or fish oil mixtures with medium chain triglycerides, on the physicochemical characteristics and injectability of curcumin-loaded PEGylated nanoemulsions. Electron paramagnetic resonance spectroscopy demonstrated the structural impact of the oil phase on the stabilizing layer of nanoemulsions, with a more pronounced stabilizing effect of curcumin observed in the fish oil nanoemulsion compared to the soybean oil one. The design of the experiment study, employed to simultaneously assess the impact of the oil phase, different PEGylated phospholipids and their concentrations, as well as the presence of curcumin, showed that not only the investigated factors alone, but also their interactions, had a significant influence on the critical quality attributes of the PEGylated nanoemulsions. Detailed physicochemical characterization of the NEs found all formulations were appropriate for parenteral administration and remained stable during two years of storage, with the preserved antioxidant activity demonstrated by DPPH and FRAP assays. In vitro release studies showed a more pronounced release of curcumin from the fish oil NEs compared to that from the soybean oil ones. The innovative in vitro injectability assessment, designed to mimic intravenous application, proved that all formulations tested in selected experimental setting could be employed in prospective in vivo studies. Overall, the current study shows the importance of oil phase selection when formulating PEGylated nanoemulsions.",
publisher = "Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "Pharmaceutics",
title = "The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions",
volume = "14",
number = "8",
pages = "1666",
doi = "10.3390/pharmaceutics14081666"
}

Đoković, J. B., Demisli, S., Savić, S. M., Marković, B. D., Cekić, N. D., Randjelović, D., Mitrović, J. R., Lunter, D. J., Papadimitriou, V., Xenakis, A.,& Savić, S. D.. (2022). The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions. in Pharmaceutics
Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)., 14(8), 1666.
https://doi.org/10.3390/pharmaceutics14081666

Đoković JB, Demisli S, Savić SM, Marković BD, Cekić ND, Randjelović D, Mitrović JR, Lunter DJ, Papadimitriou V, Xenakis A, Savić SD. The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions. in Pharmaceutics. 2022;14(8):1666.
doi:10.3390/pharmaceutics14081666 .

Đoković, Jelena B., Demisli, Sotiria, Savić, Sanela M., Marković, Bojan D., Cekić, Nebojša D., Randjelović, Danijela, Mitrović, Jelena R., Lunter, Dominique Jasmin, Papadimitriou, Vassiliki, Xenakis, Aristotelis, Savić, Snežana D., "The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions" in Pharmaceutics, 14, no. 8 (2022):1666,
https://doi.org/10.3390/pharmaceutics14081666 . .

TY  - JOUR
AU  - Đukanović, Stefana
AU  - Ganić, Tea
AU  - Lončarević, Branka
AU  - Cvetković, Stefana
AU  - Nikolić, Biljana
AU  - Tenji, Dina
AU  - Randjelović, Danijela
AU  - Mitić-Ćulafić, Dragana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5590
AB  - Aims Because the Staphylococcus aureus is one of the most well‐known pathogens associated with medical devices and nosocomial infections, the aim of the study was to examine antibiofilm potential of emodin against it.  Methods and Results Antibacterial activity was examined through microdilution assay. Antibiofilm testing included crystal violet staining of biofilm biomass and morphology analysis by Atomic force microscopy (AFM). Furthermore, aerobic respiration was monitored using the Micro‐Oxymax respirometer. For investigation of gene expression qRT‐PCR was performed. Emodin demonstrated strong antibacterial activity and ability to inhibit biofilm formation of all tested strains. The effect on preformed biofilms was spotted in few strains. AFM revealed that emodin affects biofilm structure and roughness. Monitoring of respiration under emodin treatment in planktonic and biofilm form revealed that emodin influenced aerobic respiration. Moreover, qRT‐PCR showed that emodin modulates expression of icaA, icaD, srrA and srrB genes, as well as RNAIII, and that this activity was strain‐specific.  Conclusion The results obtained in this study indicate the novel antibiofilm activity of emodin and its multiple pathways of action.  Significance and Impact of Study This is the first study that examined pathways through which emodin expressed its antibiofilm activity
PB  - Wiley
T2  - Journal of Applied Microbiology
T1  - Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms
VL  - 132
IS  - 3
SP  - 1840
EP  - 1855
DO  - 10.1111/jam.15360
ER  - 

@article{
author = "Đukanović, Stefana and Ganić, Tea and Lončarević, Branka and Cvetković, Stefana and Nikolić, Biljana and Tenji, Dina and Randjelović, Danijela and Mitić-Ćulafić, Dragana",
year = "2022",
abstract = "Aims Because the Staphylococcus aureus is one of the most well‐known pathogens associated with medical devices and nosocomial infections, the aim of the study was to examine antibiofilm potential of emodin against it.  Methods and Results Antibacterial activity was examined through microdilution assay. Antibiofilm testing included crystal violet staining of biofilm biomass and morphology analysis by Atomic force microscopy (AFM). Furthermore, aerobic respiration was monitored using the Micro‐Oxymax respirometer. For investigation of gene expression qRT‐PCR was performed. Emodin demonstrated strong antibacterial activity and ability to inhibit biofilm formation of all tested strains. The effect on preformed biofilms was spotted in few strains. AFM revealed that emodin affects biofilm structure and roughness. Monitoring of respiration under emodin treatment in planktonic and biofilm form revealed that emodin influenced aerobic respiration. Moreover, qRT‐PCR showed that emodin modulates expression of icaA, icaD, srrA and srrB genes, as well as RNAIII, and that this activity was strain‐specific.  Conclusion The results obtained in this study indicate the novel antibiofilm activity of emodin and its multiple pathways of action.  Significance and Impact of Study This is the first study that examined pathways through which emodin expressed its antibiofilm activity",
publisher = "Wiley",
journal = "Journal of Applied Microbiology",
title = "Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms",
volume = "132",
number = "3",
pages = "1840-1855",
doi = "10.1111/jam.15360"
}

Đukanović, S., Ganić, T., Lončarević, B., Cvetković, S., Nikolić, B., Tenji, D., Randjelović, D.,& Mitić-Ćulafić, D.. (2022). Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms. in Journal of Applied Microbiology
Wiley., 132(3), 1840-1855.
https://doi.org/10.1111/jam.15360

Đukanović S, Ganić T, Lončarević B, Cvetković S, Nikolić B, Tenji D, Randjelović D, Mitić-Ćulafić D. Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms. in Journal of Applied Microbiology. 2022;132(3):1840-1855.
doi:10.1111/jam.15360 .

Đukanović, Stefana, Ganić, Tea, Lončarević, Branka, Cvetković, Stefana, Nikolić, Biljana, Tenji, Dina, Randjelović, Danijela, Mitić-Ćulafić, Dragana, "Elucidating the antibiofilm activity of Frangula emodin against Staphylococcus aureus biofilms" in Journal of Applied Microbiology, 132, no. 3 (2022):1840-1855,
https://doi.org/10.1111/jam.15360 . .

TY  - JOUR
AU  - Mitrović, Jelena
AU  - Divović-Matović, Branka
AU  - Knutson, Daniel E.
AU  - Ðoković, Jelena B.
AU  - Kremenović, Aleksandar
AU  - Dobričić, Vladimir
AU  - Randjelović, Danijela
AU  - Pantelić, Ivana
AU  - Cook, James
AU  - Savić, Miroslav M.
AU  - Savić, Snežana D.
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4791
AB  - Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric disorders. In this research, based on preformulation studies, nanocrystal technology was chosen to improve the oral bioavailability of DK-I-60-3. Nanocrystal dispersions stabilized by sodium lauryl sulfate and polyvinylpyrrolidone were prepared by modified wet media milling technique, with the selection of appropriate process and formulation parameters. The nanoparticles characterization included particle size and zeta potential measurements, differential scanning calorimetry, X-ray powder diffraction, dissolution and solubility study, and in vivo pharmacokinetic experiments. Developed formulations had small uniform particle sizes and were stable for three months. Nanonization caused decreased crystallite size and induced crystal defects formation, as well as a DK-I-60-3 solubility increase. Furthermore, after oral administration of the developed formulations in rats, two to three-fold bioavailability enhancement was observed in plasma and investigated organs, including the brain.
PB  - MDPI
T2  - Pharmaceutics
T1  - Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach
VL  - 13
IS  - 8
SP  - 1188
DO  - 10.3390/pharmaceutics13081188
ER  - 

@article{
author = "Mitrović, Jelena and Divović-Matović, Branka and Knutson, Daniel E. and Ðoković, Jelena B. and Kremenović, Aleksandar and Dobričić, Vladimir and Randjelović, Danijela and Pantelić, Ivana and Cook, James and Savić, Miroslav M. and Savić, Snežana D.",
year = "2021",
abstract = "Poor water solubility of new chemical entities is considered as one of the main obstacles in drug development, as it usually leads to low bioavailability after administration. To overcome these problems, the selection of the appropriate formulation technology needs to be based on the physicochemical properties of the drug and introduced in the early stages of drug research. One example of the new potential drug substance with poor solubility is DK-I-60-3, deuterated pyrazoloquinolinone, designed for the treatment of various neuropsychiatric disorders. In this research, based on preformulation studies, nanocrystal technology was chosen to improve the oral bioavailability of DK-I-60-3. Nanocrystal dispersions stabilized by sodium lauryl sulfate and polyvinylpyrrolidone were prepared by modified wet media milling technique, with the selection of appropriate process and formulation parameters. The nanoparticles characterization included particle size and zeta potential measurements, differential scanning calorimetry, X-ray powder diffraction, dissolution and solubility study, and in vivo pharmacokinetic experiments. Developed formulations had small uniform particle sizes and were stable for three months. Nanonization caused decreased crystallite size and induced crystal defects formation, as well as a DK-I-60-3 solubility increase. Furthermore, after oral administration of the developed formulations in rats, two to three-fold bioavailability enhancement was observed in plasma and investigated organs, including the brain.",
publisher = "MDPI",
journal = "Pharmaceutics",
title = "Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach",
volume = "13",
number = "8",
pages = "1188",
doi = "10.3390/pharmaceutics13081188"
}

Mitrović, J., Divović-Matović, B., Knutson, D. E., Ðoković, J. B., Kremenović, A., Dobričić, V., Randjelović, D., Pantelić, I., Cook, J., Savić, M. M.,& Savić, S. D.. (2021). Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach. in Pharmaceutics
MDPI., 13(8), 1188.
https://doi.org/10.3390/pharmaceutics13081188

Mitrović J, Divović-Matović B, Knutson DE, Ðoković JB, Kremenović A, Dobričić V, Randjelović D, Pantelić I, Cook J, Savić MM, Savić SD. Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach. in Pharmaceutics. 2021;13(8):1188.
doi:10.3390/pharmaceutics13081188 .

Mitrović, Jelena, Divović-Matović, Branka, Knutson, Daniel E., Ðoković, Jelena B., Kremenović, Aleksandar, Dobričić, Vladimir, Randjelović, Danijela, Pantelić, Ivana, Cook, James, Savić, Miroslav M., Savić, Snežana D., "Overcoming the low oral bioavailability of deuterated pyrazoloquinolinone ligand dk-i-60-3 by nanonization: A knowledge-based approach" in Pharmaceutics, 13, no. 8 (2021):1188,
https://doi.org/10.3390/pharmaceutics13081188 . .

TY  - CONF
AU  - Joksimović, Kristina
AU  - Kodranov, Igor
AU  - Žerađanin, Aleksandra
AU  - Randjelović, Danijela
AU  - Popović, Bogdan
AU  - Manojlović, Dragan
AU  - Nakano, Takeshi
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5071
AB  - Microbial fuel cells are increasingly used as alternative energy sources. The amount of electricity produced by MFC systems is sufficient to run systems that do not require high energy consumption, such as electrochemical decomposition of wastewater from the textile dye industry. The aim of this study was to analyze the voltage and current of two parallelly-connected MFC cells used for decolorisation of the wastewater that contained Reactive Black 5 (RB5) dye.
PB  - Japan Society for Environmental Chemistry
C3  - 29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan)
T1  - Decolorisation of the textile dye using microbial fuel cells as an electricity source
SP  - 275
UR  - https://hdl.handle.net/21.15107/rcub_cer_5071
ER  - 

@conference{
author = "Joksimović, Kristina and Kodranov, Igor and Žerađanin, Aleksandra and Randjelović, Danijela and Popović, Bogdan and Manojlović, Dragan and Nakano, Takeshi and Beškoski, Vladimir",
year = "2021",
abstract = "Microbial fuel cells are increasingly used as alternative energy sources. The amount of electricity produced by MFC systems is sufficient to run systems that do not require high energy consumption, such as electrochemical decomposition of wastewater from the textile dye industry. The aim of this study was to analyze the voltage and current of two parallelly-connected MFC cells used for decolorisation of the wastewater that contained Reactive Black 5 (RB5) dye.",
publisher = "Japan Society for Environmental Chemistry",
journal = "29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan)",
title = "Decolorisation of the textile dye using microbial fuel cells as an electricity source",
pages = "275",
url = "https://hdl.handle.net/21.15107/rcub_cer_5071"
}

Joksimović, K., Kodranov, I., Žerađanin, A., Randjelović, D., Popović, B., Manojlović, D., Nakano, T.,& Beškoski, V.. (2021). Decolorisation of the textile dye using microbial fuel cells as an electricity source. in 29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan)
Japan Society for Environmental Chemistry., 275.
https://hdl.handle.net/21.15107/rcub_cer_5071

Joksimović K, Kodranov I, Žerađanin A, Randjelović D, Popović B, Manojlović D, Nakano T, Beškoski V. Decolorisation of the textile dye using microbial fuel cells as an electricity source. in 29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan). 2021;:275.
https://hdl.handle.net/21.15107/rcub_cer_5071 .

Joksimović, Kristina, Kodranov, Igor, Žerađanin, Aleksandra, Randjelović, Danijela, Popović, Bogdan, Manojlović, Dragan, Nakano, Takeshi, Beškoski, Vladimir, "Decolorisation of the textile dye using microbial fuel cells as an electricity source" in 29th Symposium on Environmental Chemistry, June 1.-3., 2021 (virtual), Osaca (Japan) (2021):275,
https://hdl.handle.net/21.15107/rcub_cer_5071 .

TY  - CONF
AU  - Joksimović, Kristina
AU  - Žerađanin, Aleksandra
AU  - Lješević, Marija
AU  - Lončarević, Branka
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5102
AB  - The use of microbial fuel cells (MFCs) for the purpose of obtaining energy from nature has 
grown in the second decade of the 21st century. Due to the lack of fossil fuels and less and less available renewable energy sources, MFCs have great potential for obtaining small amounts of electricity. Increasing attention is focused on the use of such types of energy. The aim of this paper is to analyse the current generation of two parallel-connected MFC cells and the power generation obtained in this way.
PB  - India : SRM Research Institute
C3  - International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual)
T1  - Power generation using parallel connected microbial fuel cells systems
SP  - 26
UR  - https://hdl.handle.net/21.15107/rcub_cer_5102
ER  - 

@conference{
author = "Joksimović, Kristina and Žerađanin, Aleksandra and Lješević, Marija and Lončarević, Branka and Randjelović, Danijela and Beškoski, Vladimir",
year = "2021",
abstract = "The use of microbial fuel cells (MFCs) for the purpose of obtaining energy from nature has 
grown in the second decade of the 21st century. Due to the lack of fossil fuels and less and less available renewable energy sources, MFCs have great potential for obtaining small amounts of electricity. Increasing attention is focused on the use of such types of energy. The aim of this paper is to analyse the current generation of two parallel-connected MFC cells and the power generation obtained in this way.",
publisher = "India : SRM Research Institute",
journal = "International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual)",
title = "Power generation using parallel connected microbial fuel cells systems",
pages = "26",
url = "https://hdl.handle.net/21.15107/rcub_cer_5102"
}

Joksimović, K., Žerađanin, A., Lješević, M., Lončarević, B., Randjelović, D.,& Beškoski, V.. (2021). Power generation using parallel connected microbial fuel cells systems. in International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual)
India : SRM Research Institute., 26.
https://hdl.handle.net/21.15107/rcub_cer_5102

Joksimović K, Žerađanin A, Lješević M, Lončarević B, Randjelović D, Beškoski V. Power generation using parallel connected microbial fuel cells systems. in International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual). 2021;:26.
https://hdl.handle.net/21.15107/rcub_cer_5102 .

Joksimović, Kristina, Žerađanin, Aleksandra, Lješević, Marija, Lončarević, Branka, Randjelović, Danijela, Beškoski, Vladimir, "Power generation using parallel connected microbial fuel cells systems" in International Conference on Recent Advances in Applied Sciences, Technology and Health 2021, Abstract Booklet, 03-05 March 2021 (virtual) (2021):26,
https://hdl.handle.net/21.15107/rcub_cer_5102 .

TY  - CONF
AU  - Joksimović, Kristina
AU  - Žerađanin, Aleksandra
AU  - Lončarević, Branka
AU  - Lješević, Marija
AU  - Avdalović, Jelena
AU  - Randjelović, Danijela
AU  - Beškoski, Vladimir
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5014
AB  - Global worldwide population and urbanization in general have created an increasing need for new energy sources. These sources need to be renewable, but it is also very important to respect the principles of environmental protection. Microbial fuel cells (MFC) are a green technology that has been attracting more and more attention in the last decade. MFC presents a system that produces electrical current through metabolic processes of microorganisms, such as the decomposition of organic matter. In this process, chemical energy is directly converted into electrical energy.
PB  - Belgrade : Serbian Chemical Society
C3  - 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia
T1  - Influence of Microbial Community on Power generation Using MFC System
SP  - 112
UR  - https://hdl.handle.net/21.15107/rcub_cer_5014
ER  - 

@conference{
author = "Joksimović, Kristina and Žerađanin, Aleksandra and Lončarević, Branka and Lješević, Marija and Avdalović, Jelena and Randjelović, Danijela and Beškoski, Vladimir",
year = "2021",
abstract = "Global worldwide population and urbanization in general have created an increasing need for new energy sources. These sources need to be renewable, but it is also very important to respect the principles of environmental protection. Microbial fuel cells (MFC) are a green technology that has been attracting more and more attention in the last decade. MFC presents a system that produces electrical current through metabolic processes of microorganisms, such as the decomposition of organic matter. In this process, chemical energy is directly converted into electrical energy.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia",
title = "Influence of Microbial Community on Power generation Using MFC System",
pages = "112",
url = "https://hdl.handle.net/21.15107/rcub_cer_5014"
}

Joksimović, K., Žerađanin, A., Lončarević, B., Lješević, M., Avdalović, J., Randjelović, D.,& Beškoski, V.. (2021). Influence of Microbial Community on Power generation Using MFC System. in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia
Belgrade : Serbian Chemical Society., 112.
https://hdl.handle.net/21.15107/rcub_cer_5014

Joksimović K, Žerađanin A, Lončarević B, Lješević M, Avdalović J, Randjelović D, Beškoski V. Influence of Microbial Community on Power generation Using MFC System. in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia. 2021;:112.
https://hdl.handle.net/21.15107/rcub_cer_5014 .

Joksimović, Kristina, Žerađanin, Aleksandra, Lončarević, Branka, Lješević, Marija, Avdalović, Jelena, Randjelović, Danijela, Beškoski, Vladimir, "Influence of Microbial Community on Power generation Using MFC System" in 21st European Meeting on Environmental Chemistry (EMEC21), Book of abstracts, 30 November-3 december 2021, Novi Sad, Serbia (2021):112,
https://hdl.handle.net/21.15107/rcub_cer_5014 .

TY  - JOUR
AU  - Radovanović, Milan
AU  - Ilić, Marko
AU  - Pastor, Kristian A.
AU  - Ačanski, Marijana M.
AU  - Panić, Sanja
AU  - Srdić, Vladimir V.
AU  - Randjelović, Danijela
AU  - Kojić, Tijana
AU  - Stojanović, Goran
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4236
AB  - This paper presents an application of a portable microfluidic platform based on a filter paper on which multi-walled carbon nanotubes were deposited to quickly determine the quality of olive oil by measuring electrical resistance. Three different types of filter paper with different pore sizes and different filtration rates were used in the middle of the microfluidic platform, as a material for soaking a blend of olive and high-oleic sunflower oil. The rapid prototyping xurographic technique was used to fabricate the complete microfluidic platform. For testing purposes, oil blends in various proportions were deposited through the inlet on the top of the platform. The variation in electrical resistance at room temperature was measured, using the Chemical Impedance Analyzer, successfully indicating oil proportions in measured blends. We obtained the change of resistance in the range from 0.26 MΩ to 2.79 MΩ per percentage of olive oil content, for corresponding linearity index from 0.71 to 0.99, for papers labelled with 44–45, respectively. Additionally, a prototype of electronic device was developed for acquisition and displaying measured data, based on the created microfluidic platform.
PB  - Elsevier
T2  - Food Control
T1  - Rapid detection of olive oil blends using a paper-based portable microfluidic platform
VL  - 124
SP  - 107888
DO  - 10.1016/j.foodcont.2021.107888
ER  - 

@article{
author = "Radovanović, Milan and Ilić, Marko and Pastor, Kristian A. and Ačanski, Marijana M. and Panić, Sanja and Srdić, Vladimir V. and Randjelović, Danijela and Kojić, Tijana and Stojanović, Goran",
year = "2021",
abstract = "This paper presents an application of a portable microfluidic platform based on a filter paper on which multi-walled carbon nanotubes were deposited to quickly determine the quality of olive oil by measuring electrical resistance. Three different types of filter paper with different pore sizes and different filtration rates were used in the middle of the microfluidic platform, as a material for soaking a blend of olive and high-oleic sunflower oil. The rapid prototyping xurographic technique was used to fabricate the complete microfluidic platform. For testing purposes, oil blends in various proportions were deposited through the inlet on the top of the platform. The variation in electrical resistance at room temperature was measured, using the Chemical Impedance Analyzer, successfully indicating oil proportions in measured blends. We obtained the change of resistance in the range from 0.26 MΩ to 2.79 MΩ per percentage of olive oil content, for corresponding linearity index from 0.71 to 0.99, for papers labelled with 44–45, respectively. Additionally, a prototype of electronic device was developed for acquisition and displaying measured data, based on the created microfluidic platform.",
publisher = "Elsevier",
journal = "Food Control",
title = "Rapid detection of olive oil blends using a paper-based portable microfluidic platform",
volume = "124",
pages = "107888",
doi = "10.1016/j.foodcont.2021.107888"
}

Radovanović, M., Ilić, M., Pastor, K. A., Ačanski, M. M., Panić, S., Srdić, V. V., Randjelović, D., Kojić, T.,& Stojanović, G.. (2021). Rapid detection of olive oil blends using a paper-based portable microfluidic platform. in Food Control
Elsevier., 124, 107888.
https://doi.org/10.1016/j.foodcont.2021.107888

Radovanović M, Ilić M, Pastor KA, Ačanski MM, Panić S, Srdić VV, Randjelović D, Kojić T, Stojanović G. Rapid detection of olive oil blends using a paper-based portable microfluidic platform. in Food Control. 2021;124:107888.
doi:10.1016/j.foodcont.2021.107888 .

Radovanović, Milan, Ilić, Marko, Pastor, Kristian A., Ačanski, Marijana M., Panić, Sanja, Srdić, Vladimir V., Randjelović, Danijela, Kojić, Tijana, Stojanović, Goran, "Rapid detection of olive oil blends using a paper-based portable microfluidic platform" in Food Control, 124 (2021):107888,
https://doi.org/10.1016/j.foodcont.2021.107888 . .

TY  - JOUR
AU  - Gledović, Ana
AU  - Janošević Ležaić, Aleksandra
AU  - Nikolić, Ines
AU  - Tasić-Kostov, Marija Z.
AU  - Antić-Stanković, Jelena
AU  - Krstonošić, Veljko S.
AU  - Randjelović, Danijela
AU  - Božić, Dragana
AU  - Ilić, Dušan
AU  - Tamburić, Slobodanka D.
AU  - Savić, Snežana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4243
AB  - This study focuses on the development of biocompatible oil-in-water (O/W) nanoemulsions
based on polyglycerol esters, as promising carriers for natural actives: red raspberry seed oil—RO
and hydro-glycolic fruit extracts from red raspberry—RE and French oak—FE. Nanoemulsions
were obtained via phase inversion composition (PIC) method at room temperature by dilution of
microemulsion phase, confirmed by visual appearance, percentage of transmittance, microscopic,
rheological and differential scanning calorimetry (DSC) investigations. The results have shown that
the basic RO-loaded formulation could be further enriched with hydro-glycolic fruit extracts from
red raspberry or French oak, while keeping a semi-transparent appearance due to the fine droplet
size (Z-ave: 50 to 70 nm, PDI value _ 0.1). The highest antioxidant activity (~92% inhibition of the
DPPH radical) was achieved in the formulation containing both lipophilic (RO) and hydrophilic
antioxidants (FE), due to their synergistic effect. The nanoemulsion carrier significantly increased
the selective cytotoxic effect of RO towards malignant melanoma (Fem-X) cells, compared to normal
human keratinocytes (HaCaT). In vivo study on human volunteers showed satisfactory safety profiles
and significant improvement in skin hydration during 2 h after application for all nanoemulsions.
Therefore, polyglycerol ester-based nanoemulsions can be promoted as effective carriers for red
raspberry seed oil and/or hydro-glycolic fruit extracts in topical formulations intended for skin
protection and hydration.
PB  - MDPI
T2  - Nanomaterials
T1  - Polyglycerol Ester-Based Low Energy Nanoemulsions with Red Raspberry Seed Oil and Fruit Extracts: Formulation Development toward Effective In Vitro/In Vivo Bioperformance
VL  - 11
IS  - 1
SP  - 1
EP  - 21
DO  - 10.3390/nano11010217
ER  - 

@article{
author = "Gledović, Ana and Janošević Ležaić, Aleksandra and Nikolić, Ines and Tasić-Kostov, Marija Z. and Antić-Stanković, Jelena and Krstonošić, Veljko S. and Randjelović, Danijela and Božić, Dragana and Ilić, Dušan and Tamburić, Slobodanka D. and Savić, Snežana",
year = "2021",
abstract = "This study focuses on the development of biocompatible oil-in-water (O/W) nanoemulsions
based on polyglycerol esters, as promising carriers for natural actives: red raspberry seed oil—RO
and hydro-glycolic fruit extracts from red raspberry—RE and French oak—FE. Nanoemulsions
were obtained via phase inversion composition (PIC) method at room temperature by dilution of
microemulsion phase, confirmed by visual appearance, percentage of transmittance, microscopic,
rheological and differential scanning calorimetry (DSC) investigations. The results have shown that
the basic RO-loaded formulation could be further enriched with hydro-glycolic fruit extracts from
red raspberry or French oak, while keeping a semi-transparent appearance due to the fine droplet
size (Z-ave: 50 to 70 nm, PDI value _ 0.1). The highest antioxidant activity (~92% inhibition of the
DPPH radical) was achieved in the formulation containing both lipophilic (RO) and hydrophilic
antioxidants (FE), due to their synergistic effect. The nanoemulsion carrier significantly increased
the selective cytotoxic effect of RO towards malignant melanoma (Fem-X) cells, compared to normal
human keratinocytes (HaCaT). In vivo study on human volunteers showed satisfactory safety profiles
and significant improvement in skin hydration during 2 h after application for all nanoemulsions.
Therefore, polyglycerol ester-based nanoemulsions can be promoted as effective carriers for red
raspberry seed oil and/or hydro-glycolic fruit extracts in topical formulations intended for skin
protection and hydration.",
publisher = "MDPI",
journal = "Nanomaterials",
title = "Polyglycerol Ester-Based Low Energy Nanoemulsions with Red Raspberry Seed Oil and Fruit Extracts: Formulation Development toward Effective In Vitro/In Vivo Bioperformance",
volume = "11",
number = "1",
pages = "1-21",
doi = "10.3390/nano11010217"
}

Gledović, A., Janošević Ležaić, A., Nikolić, I., Tasić-Kostov, M. Z., Antić-Stanković, J., Krstonošić, V. S., Randjelović, D., Božić, D., Ilić, D., Tamburić, S. D.,& Savić, S.. (2021). Polyglycerol Ester-Based Low Energy Nanoemulsions with Red Raspberry Seed Oil and Fruit Extracts: Formulation Development toward Effective In Vitro/In Vivo Bioperformance. in Nanomaterials
MDPI., 11(1), 1-21.
https://doi.org/10.3390/nano11010217

Gledović A, Janošević Ležaić A, Nikolić I, Tasić-Kostov MZ, Antić-Stanković J, Krstonošić VS, Randjelović D, Božić D, Ilić D, Tamburić SD, Savić S. Polyglycerol Ester-Based Low Energy Nanoemulsions with Red Raspberry Seed Oil and Fruit Extracts: Formulation Development toward Effective In Vitro/In Vivo Bioperformance. in Nanomaterials. 2021;11(1):1-21.
doi:10.3390/nano11010217 .

Gledović, Ana, Janošević Ležaić, Aleksandra, Nikolić, Ines, Tasić-Kostov, Marija Z., Antić-Stanković, Jelena, Krstonošić, Veljko S., Randjelović, Danijela, Božić, Dragana, Ilić, Dušan, Tamburić, Slobodanka D., Savić, Snežana, "Polyglycerol Ester-Based Low Energy Nanoemulsions with Red Raspberry Seed Oil and Fruit Extracts: Formulation Development toward Effective In Vitro/In Vivo Bioperformance" in Nanomaterials, 11, no. 1 (2021):1-21,
https://doi.org/10.3390/nano11010217 . .

TY  - JOUR
AU  - Ðoković, Jelena B.
AU  - Savić, Sanela M.
AU  - Mitrović, Jelena R.
AU  - Nikolić, Ines
AU  - Marković, Bojan D.
AU  - Randjelović, Danijela
AU  - Antić-Stanković, Jelena
AU  - Božić, Dragana
AU  - Cekić, Nebojša D.
AU  - Stevanović, Vladimir
AU  - Batinić, Bojan
AU  - Aranđelović, Jovana
AU  - Savić, Miroslav M.
AU  - Savić, Snežana D.
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4822
AB  - The current study describes the experimental design guided development of PEGylated nanoemulsions as parenteral delivery systems for curcumin, a powerful antioxidant, as well as the evaluation of their physicochemical characteristics and antioxidant activity during the two years of storage. Experimental design setup helped development of nanoemulsion templates with critical quality attributes in line with parenteral application route. Curcumin-loaded nanoemulsions showed mean droplet size about 105 nm, polydispersity index <0.15, zeta potential of −40 mV, and acceptable osmolality of about 550 mOsm/kg. After two years of storage at room temperature, all formulations remained stable. Moreover, antioxidant activity remained intact, as demonstrated by DPPH (IC50 values 0.078–0.075 mg/mL after two years) and FRAPS assays. In vitro release testing proved that PEGylated phospholipids slowed down the curcumin release from nanoemulsions. The nanoemulsion carrier has been proven safe by the MTT test conducted with MRC-5 cell line, and effective on LS cell line. Results from the pharmacokinetic pilot study implied the PEGylated nanoemulsions improved plasma residence of curcumin 20 min after intravenous administration, compared to the non-PEGylated nanoemulsion (two-fold higher) or curcumin solution (three-fold higher). Overall, conclusion suggests that developed PEGylated nanoemulsions present an acceptable delivery system for parenteral administration of curcumin, being effective in preserving its stability and antioxidant capacity at the level highly comparable to the initial findings.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats
VL  - 22
IS  - 15
IS  - 7991
DO  - 10.3390/ijms22157991
ER  - 

@article{
author = "Ðoković, Jelena B. and Savić, Sanela M. and Mitrović, Jelena R. and Nikolić, Ines and Marković, Bojan D. and Randjelović, Danijela and Antić-Stanković, Jelena and Božić, Dragana and Cekić, Nebojša D. and Stevanović, Vladimir and Batinić, Bojan and Aranđelović, Jovana and Savić, Miroslav M. and Savić, Snežana D.",
year = "2021",
abstract = "The current study describes the experimental design guided development of PEGylated nanoemulsions as parenteral delivery systems for curcumin, a powerful antioxidant, as well as the evaluation of their physicochemical characteristics and antioxidant activity during the two years of storage. Experimental design setup helped development of nanoemulsion templates with critical quality attributes in line with parenteral application route. Curcumin-loaded nanoemulsions showed mean droplet size about 105 nm, polydispersity index <0.15, zeta potential of −40 mV, and acceptable osmolality of about 550 mOsm/kg. After two years of storage at room temperature, all formulations remained stable. Moreover, antioxidant activity remained intact, as demonstrated by DPPH (IC50 values 0.078–0.075 mg/mL after two years) and FRAPS assays. In vitro release testing proved that PEGylated phospholipids slowed down the curcumin release from nanoemulsions. The nanoemulsion carrier has been proven safe by the MTT test conducted with MRC-5 cell line, and effective on LS cell line. Results from the pharmacokinetic pilot study implied the PEGylated nanoemulsions improved plasma residence of curcumin 20 min after intravenous administration, compared to the non-PEGylated nanoemulsion (two-fold higher) or curcumin solution (three-fold higher). Overall, conclusion suggests that developed PEGylated nanoemulsions present an acceptable delivery system for parenteral administration of curcumin, being effective in preserving its stability and antioxidant capacity at the level highly comparable to the initial findings.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats",
volume = "22",
number = "15, 7991",
doi = "10.3390/ijms22157991"
}

Ðoković, J. B., Savić, S. M., Mitrović, J. R., Nikolić, I., Marković, B. D., Randjelović, D., Antić-Stanković, J., Božić, D., Cekić, N. D., Stevanović, V., Batinić, B., Aranđelović, J., Savić, M. M.,& Savić, S. D.. (2021). Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats. in International Journal of Molecular Sciences
MDPI., 22(15).
https://doi.org/10.3390/ijms22157991

Ðoković JB, Savić SM, Mitrović JR, Nikolić I, Marković BD, Randjelović D, Antić-Stanković J, Božić D, Cekić ND, Stevanović V, Batinić B, Aranđelović J, Savić MM, Savić SD. Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats. in International Journal of Molecular Sciences. 2021;22(15).
doi:10.3390/ijms22157991 .

Ðoković, Jelena B., Savić, Sanela M., Mitrović, Jelena R., Nikolić, Ines, Marković, Bojan D., Randjelović, Danijela, Antić-Stanković, Jelena, Božić, Dragana, Cekić, Nebojša D., Stevanović, Vladimir, Batinić, Bojan, Aranđelović, Jovana, Savić, Miroslav M., Savić, Snežana D., "Curcumin loaded pegylated nanoemulsions designed for maintained antioxidant effects and improved bioavailability: A pilot study on rats" in International Journal of Molecular Sciences, 22, no. 15 (2021),
https://doi.org/10.3390/ijms22157991 . .

TY  - GEN
AU  - Jovanov, Vladislav
AU  - Sarajlić, Milija
AU  - Randjelović, Danijela
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5919
AB  - Ово техничко решење омогућава да се симулира изглед површине танког филма нанешног на текстуирани супстрат. Тако симулирана површина се затим може користити у програму за анализу отвореног угла површине ради анализе потенциjалне поjаве електричних
дефеката, или комерциjалним програмима попут COMSOL и ANSYS Lumerical, ради предвиђања оптичких карактеристика танкослоjних микрокристалних силициjумских ћелиjа
нумеричким путем. Коришћењем овог техничког решења практично се остваруjе виртуелна фабрикациjа танкослоjних соларних ћелиjа чиме се унапређуjе процес оптимизациjе
и значаjно штеди на лабораториjским ресурсима.
PB  - ИХТМ - Центар за микроелектронске технологиjе, Универзитет у Београду
T1  - Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate
UR  - https://hdl.handle.net/21.15107/rcub_cer_5919
ER  - 

@misc{
author = "Jovanov, Vladislav and Sarajlić, Milija and Randjelović, Danijela",
year = "2021",
abstract = "Ово техничко решење омогућава да се симулира изглед површине танког филма нанешног на текстуирани супстрат. Тако симулирана површина се затим може користити у програму за анализу отвореног угла површине ради анализе потенциjалне поjаве електричних
дефеката, или комерциjалним програмима попут COMSOL и ANSYS Lumerical, ради предвиђања оптичких карактеристика танкослоjних микрокристалних силициjумских ћелиjа
нумеричким путем. Коришћењем овог техничког решења практично се остваруjе виртуелна фабрикациjа танкослоjних соларних ћелиjа чиме се унапређуjе процес оптимизациjе
и значаjно штеди на лабораториjским ресурсима.",
publisher = "ИХТМ - Центар за микроелектронске технологиjе, Универзитет у Београду",
title = "Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate",
url = "https://hdl.handle.net/21.15107/rcub_cer_5919"
}

Jovanov, V., Sarajlić, M.,& Randjelović, D.. (2021). Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate. 
ИХТМ - Центар за микроелектронске технологиjе, Универзитет у Београду..
https://hdl.handle.net/21.15107/rcub_cer_5919

Jovanov V, Sarajlić M, Randjelović D. Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate. 2021;.
https://hdl.handle.net/21.15107/rcub_cer_5919 .

Jovanov, Vladislav, Sarajlić, Milija, Randjelović, Danijela, "Softversko rešenje za simulaciju izgleda površine tankih filmova nanešenih na tekstuirane supstrate" (2021),
https://hdl.handle.net/21.15107/rcub_cer_5919 .

TY  - JOUR
AU  - Nikolić, Ines
AU  - Antić-Stanković, Jelena
AU  - Božić, Dragana
AU  - Randjelović, Danijela
AU  - Marković, Bojan D.
AU  - Lunter, Dominique Jasmin
AU  - Kremenović, Aleksandar
AU  - Savić, Miroslav M.
AU  - Savić, Snežana
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3711
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3720
AB  - As the number of poorly soluble drugs is increasing, nanocrystals have become very interesting due to wide range of application possibilities. Curcuminwas used as a model active ingredient in this work. Even though it has many proven positive effects, due to its physicochemical issues, its possibilities have not been fully exploited. The goal of this work was to select optimal conditions for a top-down method for curcumin nanosuspension production, and to perform their comprehensive characterization applying complementary methodologies: dynamic light scattering, polarization and atomic force microscopy, thermal analysis, X-ray powder diffraction, antioxidant activity evaluation, release kinetics assessment, and screening of potential biological effects applying cell viability assays on normal human lung fibroblasts, human melanoma and human adenomacarcinoma cells. After 30 min of milling, nanosuspensions stabilized by polysorbate 80 and by its combinations with sucrose palmitate showed good stability, while curcumin crystal structure was unaltered. Obtained nanocrystals were well defined, with average diameter 120-170 nm and PDI of about 0.25, zeta potential was below -30 mV and pH~5 for all formulations. Nanodispersions exhibited high antioxidant potential and improved dissolution rate compared to the corresponding coarse dispersions. Although curcumin nanodispersions exhibited significant antiproliferative effect to each cancer cell line, the highest effect was towards adenocarcinoma cells.
PB  - Walter de Gruyter GmbH
T2  - Reviews on Advanced Materials Science
T1  - Curcumin Nanonization Using An Alternative Small-Scale Production Unit: Selection of Proper Stabilizer Applying Basic Physicochemical Consideration and Biological Activity Assessment of Nanocrystals
VL  - 59
IS  - 1
SP  - 406
EP  - 424
DO  - 10.1515/rams-2020-0043
ER  - 

@article{
author = "Nikolić, Ines and Antić-Stanković, Jelena and Božić, Dragana and Randjelović, Danijela and Marković, Bojan D. and Lunter, Dominique Jasmin and Kremenović, Aleksandar and Savić, Miroslav M. and Savić, Snežana",
year = "2020",
abstract = "As the number of poorly soluble drugs is increasing, nanocrystals have become very interesting due to wide range of application possibilities. Curcuminwas used as a model active ingredient in this work. Even though it has many proven positive effects, due to its physicochemical issues, its possibilities have not been fully exploited. The goal of this work was to select optimal conditions for a top-down method for curcumin nanosuspension production, and to perform their comprehensive characterization applying complementary methodologies: dynamic light scattering, polarization and atomic force microscopy, thermal analysis, X-ray powder diffraction, antioxidant activity evaluation, release kinetics assessment, and screening of potential biological effects applying cell viability assays on normal human lung fibroblasts, human melanoma and human adenomacarcinoma cells. After 30 min of milling, nanosuspensions stabilized by polysorbate 80 and by its combinations with sucrose palmitate showed good stability, while curcumin crystal structure was unaltered. Obtained nanocrystals were well defined, with average diameter 120-170 nm and PDI of about 0.25, zeta potential was below -30 mV and pH~5 for all formulations. Nanodispersions exhibited high antioxidant potential and improved dissolution rate compared to the corresponding coarse dispersions. Although curcumin nanodispersions exhibited significant antiproliferative effect to each cancer cell line, the highest effect was towards adenocarcinoma cells.",
publisher = "Walter de Gruyter GmbH",
journal = "Reviews on Advanced Materials Science",
title = "Curcumin Nanonization Using An Alternative Small-Scale Production Unit: Selection of Proper Stabilizer Applying Basic Physicochemical Consideration and Biological Activity Assessment of Nanocrystals",
volume = "59",
number = "1",
pages = "406-424",
doi = "10.1515/rams-2020-0043"
}

Nikolić, I., Antić-Stanković, J., Božić, D., Randjelović, D., Marković, B. D., Lunter, D. J., Kremenović, A., Savić, M. M.,& Savić, S.. (2020). Curcumin Nanonization Using An Alternative Small-Scale Production Unit: Selection of Proper Stabilizer Applying Basic Physicochemical Consideration and Biological Activity Assessment of Nanocrystals. in Reviews on Advanced Materials Science
Walter de Gruyter GmbH., 59(1), 406-424.
https://doi.org/10.1515/rams-2020-0043

Nikolić I, Antić-Stanković J, Božić D, Randjelović D, Marković BD, Lunter DJ, Kremenović A, Savić MM, Savić S. Curcumin Nanonization Using An Alternative Small-Scale Production Unit: Selection of Proper Stabilizer Applying Basic Physicochemical Consideration and Biological Activity Assessment of Nanocrystals. in Reviews on Advanced Materials Science. 2020;59(1):406-424.
doi:10.1515/rams-2020-0043 .

Nikolić, Ines, Antić-Stanković, Jelena, Božić, Dragana, Randjelović, Danijela, Marković, Bojan D., Lunter, Dominique Jasmin, Kremenović, Aleksandar, Savić, Miroslav M., Savić, Snežana, "Curcumin Nanonization Using An Alternative Small-Scale Production Unit: Selection of Proper Stabilizer Applying Basic Physicochemical Consideration and Biological Activity Assessment of Nanocrystals" in Reviews on Advanced Materials Science, 59, no. 1 (2020):406-424,
https://doi.org/10.1515/rams-2020-0043 . .

TY  - JOUR
AU  - Bošković, Marko V.
AU  - Sarajlić, Milija
AU  - Frantlović, Miloš
AU  - Smiljanić, Milče M.
AU  - Randjelović, Danijela
AU  - Cvetanović Zobenica, Katarina
AU  - Vasiljević-Radović, Dana
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3678
AB  - An aluminum-based, self-powered, miniaturized sensor for breath humidity detection is presented. The sensor is designed as an interdigitated capacitor made out of sputtered aluminum 1 % silicon (Al 1 %Si) thin film, 700 nm thickness, with digits 1.5 mm long, 0.01 mm wide and 0.01 mm clearance between them. The voltage on the open end of the sensor is generated when the surface is covered with a thin layer of water vapor, for instance if a person blows on it. The voltage generated is up to 1.5 V. The voltage generation is based on an electrochemical process of interaction between aluminum, water and oxygen from air, similar to the operation of an aluminum-air battery. The rise time of the signal during water vapor (or breath) detection is as small as 10 ms which makes it one of the fastest humidity sensors reported to date. The relaxation time is in the range of 50 ms. To make detection possible, the sensor surface needs to be activated by native oxide removal with the help of electric current and de-mineralized water droplet. Usability of the sensor was demonstrated in the detection of human breathing, where the sensor managed to follow the cycles of inhaling and exhaling.
PB  - Elsevier
T2  - Sensors and Actuators: B. Chemical
T1  - Aluminum-based self-powered hyper-fast miniaturized sensor for breath humidity detection
VL  - 321
SP  - 128635
DO  - 10.1016/j.snb.2020.128635
ER  - 

@article{
author = "Bošković, Marko V. and Sarajlić, Milija and Frantlović, Miloš and Smiljanić, Milče M. and Randjelović, Danijela and Cvetanović Zobenica, Katarina and Vasiljević-Radović, Dana",
year = "2020",
abstract = "An aluminum-based, self-powered, miniaturized sensor for breath humidity detection is presented. The sensor is designed as an interdigitated capacitor made out of sputtered aluminum 1 % silicon (Al 1 %Si) thin film, 700 nm thickness, with digits 1.5 mm long, 0.01 mm wide and 0.01 mm clearance between them. The voltage on the open end of the sensor is generated when the surface is covered with a thin layer of water vapor, for instance if a person blows on it. The voltage generated is up to 1.5 V. The voltage generation is based on an electrochemical process of interaction between aluminum, water and oxygen from air, similar to the operation of an aluminum-air battery. The rise time of the signal during water vapor (or breath) detection is as small as 10 ms which makes it one of the fastest humidity sensors reported to date. The relaxation time is in the range of 50 ms. To make detection possible, the sensor surface needs to be activated by native oxide removal with the help of electric current and de-mineralized water droplet. Usability of the sensor was demonstrated in the detection of human breathing, where the sensor managed to follow the cycles of inhaling and exhaling.",
publisher = "Elsevier",
journal = "Sensors and Actuators: B. Chemical",
title = "Aluminum-based self-powered hyper-fast miniaturized sensor for breath humidity detection",
volume = "321",
pages = "128635",
doi = "10.1016/j.snb.2020.128635"
}

Bošković, M. V., Sarajlić, M., Frantlović, M., Smiljanić, M. M., Randjelović, D., Cvetanović Zobenica, K.,& Vasiljević-Radović, D.. (2020). Aluminum-based self-powered hyper-fast miniaturized sensor for breath humidity detection. in Sensors and Actuators: B. Chemical
Elsevier., 321, 128635.
https://doi.org/10.1016/j.snb.2020.128635

Bošković MV, Sarajlić M, Frantlović M, Smiljanić MM, Randjelović D, Cvetanović Zobenica K, Vasiljević-Radović D. Aluminum-based self-powered hyper-fast miniaturized sensor for breath humidity detection. in Sensors and Actuators: B. Chemical. 2020;321:128635.
doi:10.1016/j.snb.2020.128635 .

Bošković, Marko V., Sarajlić, Milija, Frantlović, Miloš, Smiljanić, Milče M., Randjelović, Danijela, Cvetanović Zobenica, Katarina, Vasiljević-Radović, Dana, "Aluminum-based self-powered hyper-fast miniaturized sensor for breath humidity detection" in Sensors and Actuators: B. Chemical, 321 (2020):128635,
https://doi.org/10.1016/j.snb.2020.128635 . .