TY  - JOUR
AU  - Gopčević, Kristina
AU  - Gojgić-Cvijović, Gordana
AU  - Pavlović, Mirjana
AU  - Milićević, Živana
AU  - Stevanović, D.
PY  - 2006
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/249
AB  - The effect of some membrane active ionophoric antibiotics on the amplitude of contractions of isolated rat heart right ventricle was studied. The effects of polyether nigericin, polyene amphotericin B and peptide antibiotic polymyxin B were examined. Nigericin in a concentration of 1.38 _mol/L exerts a positive inotropic effect with its maximal value (+29%) 15 minutes after application. Amphotericin B in a concentration of 1.08 _mol/L caused a positive inotropic effect, which was maximal in the 30th minute of the experiment (+28%). Polymyxin B in a concentration of 0.84 _mol/L caused a positive inotropic effect, which was maximal (+32%) 20 minutes after application.
AB  - Amfotericin B, nigericin i polimiksin B pokazuju pozitivni inotropni efekat na izolovanu desnu komoru srca pacova. Imajući u vidu nižu toksičnost jonofornih antibiotika u poređenju sa glikozidnim supstancama koje se u farmakoterapiji koriste kao kardiotonici i visoku selektivnost jonofora prema nekim katjonima, dobijeni rezultati ukazuju na moguću upotrebu ovih supstanci u poboljšanju funkcije insuficijentnog miokarda.
T2  - Acta veterinaria
T1  - The membrane active antibiotics effects on rat heart myocardium
T1  - Efekti antibiotika koji deluju na ćelijske membrane na srce pacova
VL  - 56
IS  - 2-3
SP  - 149
EP  - 156
DO  - 10.2298/AVB0603149G
ER  - 

@article{
author = "Gopčević, Kristina and Gojgić-Cvijović, Gordana and Pavlović, Mirjana and Milićević, Živana and Stevanović, D.",
year = "2006",
abstract = "The effect of some membrane active ionophoric antibiotics on the amplitude of contractions of isolated rat heart right ventricle was studied. The effects of polyether nigericin, polyene amphotericin B and peptide antibiotic polymyxin B were examined. Nigericin in a concentration of 1.38 _mol/L exerts a positive inotropic effect with its maximal value (+29%) 15 minutes after application. Amphotericin B in a concentration of 1.08 _mol/L caused a positive inotropic effect, which was maximal in the 30th minute of the experiment (+28%). Polymyxin B in a concentration of 0.84 _mol/L caused a positive inotropic effect, which was maximal (+32%) 20 minutes after application., Amfotericin B, nigericin i polimiksin B pokazuju pozitivni inotropni efekat na izolovanu desnu komoru srca pacova. Imajući u vidu nižu toksičnost jonofornih antibiotika u poređenju sa glikozidnim supstancama koje se u farmakoterapiji koriste kao kardiotonici i visoku selektivnost jonofora prema nekim katjonima, dobijeni rezultati ukazuju na moguću upotrebu ovih supstanci u poboljšanju funkcije insuficijentnog miokarda.",
journal = "Acta veterinaria",
title = "The membrane active antibiotics effects on rat heart myocardium, Efekti antibiotika koji deluju na ćelijske membrane na srce pacova",
volume = "56",
number = "2-3",
pages = "149-156",
doi = "10.2298/AVB0603149G"
}

Gopčević, K., Gojgić-Cvijović, G., Pavlović, M., Milićević, Ž.,& Stevanović, D.. (2006). The membrane active antibiotics effects on rat heart myocardium. in Acta veterinaria, 56(2-3), 149-156.
https://doi.org/10.2298/AVB0603149G

Gopčević K, Gojgić-Cvijović G, Pavlović M, Milićević Ž, Stevanović D. The membrane active antibiotics effects on rat heart myocardium. in Acta veterinaria. 2006;56(2-3):149-156.
doi:10.2298/AVB0603149G .

Gopčević, Kristina, Gojgić-Cvijović, Gordana, Pavlović, Mirjana, Milićević, Živana, Stevanović, D., "The membrane active antibiotics effects on rat heart myocardium" in Acta veterinaria, 56, no. 2-3 (2006):149-156,
https://doi.org/10.2298/AVB0603149G . .

TY  - JOUR
AU  - Gojgić-Cvijović, Gordana
AU  - Karadžić, Ivanka
AU  - Gopčević, Kristina
AU  - Borozan, Sunčica
PY  - 2006
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/228
AB  - Streptomycetes are common soil bacteria that grow in a filamentous form and produced spores. Secondary metabolites, particularly antibiotics, as well as extracellular enzymes produced by them have very significant role in the process of differentiation. The Slreptomyces hygroscopicus CH-7 strain produces polyketide antibiotics and an extracellular proteolytic complex. The aim of this work was to establish the influence of transcription and translation inhibitors on biosynthesis of polyene antibiotic and proteolytic enzymes. The inhibitors were added at inoculation and at specific time intervals of fermentation. The production of hexaene H-85 is susceptible to rifamycin (transcription inhibitor) and chloramphenicol (translation inhibitor). Rifamycin reduces the production and trypsin like protease (TLP) and aminopeptidase (AP). while chloramphenicol acts only on TLP. Simultaneously these inhibitors almost have no effect on strain growth.
AB  - Streptomicete su gram pozitivne bakterije čije je najvažnije stanište zemlja. Pri rastu na čvrstim podlogama i u submerznim uslovima grade supstratni i vazdušni micelijum. Morfološka diferencijacija je praćena produkcijom sekundarnih metabolita kao što su antibiotici, a i različitih hidrolitičkih enzima. Za mikroorganizme koji ih proizvode antibiotici predstavljaju kompetitivno oružje, agense za transport metala kao i efektore diferencijacije. Proteolitički enzimi, takođe, imaju određenu ulogu u razvojnom ciklusu aktinomiceta. Na primer, uključeni su u procese građenja vazdušnog micelija i sporulaciju. Soj Streptomyces hygroscopicus CH-7 pri fermentaciji proizvodi antibiotike poliketidne strukture i smesu ekstracelularnih proteolitičkih enzima. U ovom radu je ispitivan uticaj antibiotika rifamicina i hloramfenikola, inhibitora transkripcije i translacije, na produkciju polienskog antibiotika heksaena H-85 i proteolitičkih enzima. Inhibited su dodavani pri inokulaciji (O h) i u različitim vremenskim intervalima fermentacije (12-48 h). Dejstvom antibiotika inhibitora transkripcije i translacije utvrdjeno je da se enzim polien sintetaza transkribuje do 12. časa, a translacija teče do 48. časa fermentacije. Dodatak rifamicina pri zasejavanju drastično snižava proteolitičku aktivnost, a u kasnijim fazama izaziva smanjenje (36-80%). Hloramfenikol smanjuje produkciju tripsinu slične proteaze. ali nema dejstvo na aminopeptidaznu aktivnost. Rifamicin i hloramfenikol ne pokazuju značajno inhibitorno dejstvo na rast soja.
T2  - Acta biologica iugoslavica - serija B: Mikrobiologija
T1  - The effect of rifamycin and chloramphenicol on antibiotic and protease production by Streptomyces hygroscopicus CH-7
T1  - Dejstvo rifamicina i hloramfenikola na produkciju antibiotika i proteaza soja Streptomyces hygroscopicus CH-7
VL  - 43
IS  - 1
SP  - 31
EP  - 40
UR  - https://hdl.handle.net/21.15107/rcub_cer_228
ER  - 

@article{
author = "Gojgić-Cvijović, Gordana and Karadžić, Ivanka and Gopčević, Kristina and Borozan, Sunčica",
year = "2006",
abstract = "Streptomycetes are common soil bacteria that grow in a filamentous form and produced spores. Secondary metabolites, particularly antibiotics, as well as extracellular enzymes produced by them have very significant role in the process of differentiation. The Slreptomyces hygroscopicus CH-7 strain produces polyketide antibiotics and an extracellular proteolytic complex. The aim of this work was to establish the influence of transcription and translation inhibitors on biosynthesis of polyene antibiotic and proteolytic enzymes. The inhibitors were added at inoculation and at specific time intervals of fermentation. The production of hexaene H-85 is susceptible to rifamycin (transcription inhibitor) and chloramphenicol (translation inhibitor). Rifamycin reduces the production and trypsin like protease (TLP) and aminopeptidase (AP). while chloramphenicol acts only on TLP. Simultaneously these inhibitors almost have no effect on strain growth., Streptomicete su gram pozitivne bakterije čije je najvažnije stanište zemlja. Pri rastu na čvrstim podlogama i u submerznim uslovima grade supstratni i vazdušni micelijum. Morfološka diferencijacija je praćena produkcijom sekundarnih metabolita kao što su antibiotici, a i različitih hidrolitičkih enzima. Za mikroorganizme koji ih proizvode antibiotici predstavljaju kompetitivno oružje, agense za transport metala kao i efektore diferencijacije. Proteolitički enzimi, takođe, imaju određenu ulogu u razvojnom ciklusu aktinomiceta. Na primer, uključeni su u procese građenja vazdušnog micelija i sporulaciju. Soj Streptomyces hygroscopicus CH-7 pri fermentaciji proizvodi antibiotike poliketidne strukture i smesu ekstracelularnih proteolitičkih enzima. U ovom radu je ispitivan uticaj antibiotika rifamicina i hloramfenikola, inhibitora transkripcije i translacije, na produkciju polienskog antibiotika heksaena H-85 i proteolitičkih enzima. Inhibited su dodavani pri inokulaciji (O h) i u različitim vremenskim intervalima fermentacije (12-48 h). Dejstvom antibiotika inhibitora transkripcije i translacije utvrdjeno je da se enzim polien sintetaza transkribuje do 12. časa, a translacija teče do 48. časa fermentacije. Dodatak rifamicina pri zasejavanju drastično snižava proteolitičku aktivnost, a u kasnijim fazama izaziva smanjenje (36-80%). Hloramfenikol smanjuje produkciju tripsinu slične proteaze. ali nema dejstvo na aminopeptidaznu aktivnost. Rifamicin i hloramfenikol ne pokazuju značajno inhibitorno dejstvo na rast soja.",
journal = "Acta biologica iugoslavica - serija B: Mikrobiologija",
title = "The effect of rifamycin and chloramphenicol on antibiotic and protease production by Streptomyces hygroscopicus CH-7, Dejstvo rifamicina i hloramfenikola na produkciju antibiotika i proteaza soja Streptomyces hygroscopicus CH-7",
volume = "43",
number = "1",
pages = "31-40",
url = "https://hdl.handle.net/21.15107/rcub_cer_228"
}

Gojgić-Cvijović, G., Karadžić, I., Gopčević, K.,& Borozan, S.. (2006). The effect of rifamycin and chloramphenicol on antibiotic and protease production by Streptomyces hygroscopicus CH-7. in Acta biologica iugoslavica - serija B: Mikrobiologija, 43(1), 31-40.
https://hdl.handle.net/21.15107/rcub_cer_228

Gojgić-Cvijović G, Karadžić I, Gopčević K, Borozan S. The effect of rifamycin and chloramphenicol on antibiotic and protease production by Streptomyces hygroscopicus CH-7. in Acta biologica iugoslavica - serija B: Mikrobiologija. 2006;43(1):31-40.
https://hdl.handle.net/21.15107/rcub_cer_228 .

Gojgić-Cvijović, Gordana, Karadžić, Ivanka, Gopčević, Kristina, Borozan, Sunčica, "The effect of rifamycin and chloramphenicol on antibiotic and protease production by Streptomyces hygroscopicus CH-7" in Acta biologica iugoslavica - serija B: Mikrobiologija, 43, no. 1 (2006):31-40,
https://hdl.handle.net/21.15107/rcub_cer_228 .

TY  - JOUR
AU  - Vučetić, Jovan
AU  - Gojgić-Cvijović, Gordana
AU  - Gopčević, Kristina
AU  - Nastasijević, Branislav
PY  - 2004
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/161
AB  - Potato represents almost complete food. Beside carbohydrates, it contains low quantities of lipids and proteins, too. Nutritional value of potato comes from its most important constituent - carbohydrates. Starch is a main complex polysaccharide in potato but it is also a component of cereals, leguminoses vegetables and fruits. Potato contains low quantity of monosaccharide glucose and disaccharide sucrose. Potato has a high nutritional value because of high energy liberated by starch combustion -16,75 kj/1 g of substance. In an organism starch is being hydrolysedby enzyme action: saliva a-amilase and duodenum pancreatic a-amilase induodenum convert starch into maltose units. Potato contajns low quantity of proteins (2,1 %) separable by ele-ctrophoresis into 40 fractions. Main group of proteins are fractions with molecular masses 17-20 kD. All essential am/no acids are present in globular protein tuberin. Potato contains higher amount of aminoacids lysine and histidine than human milk. Potato contains almost all B group vitamins in low quantities, as well as A, H, C and E vitamins. More than 20 minerals were found in potato ash: macroelements potassium, phosphorus, iron and microelements copper, zinc, magnesium, chromium and molybdenum; they have an important role in metabolic pathways. Also, potato contains some enzymes. Potato is used in folk medicine for ulcer and gastritis treatment and in farmaceutical and food industry.
AB  - Krompir je složena namirnica koja pored ugljenih hidrata sadrži u manjim količinama i proteine i lipide. Hranljiva vrednost krompira police od njegovog najvažnijeg sastojka - ugljenih hidrata. Skrob je glavni složeni ugljeni hidrat krtole krompira ali se on nalazi kao rezervni polisaharid i kod žitarica, mahunarki, u povrću i voću. Od monosaharida i disaharida u krtoli krompira nalaze se u ma/im količinama glukoza i saharoza. Hranljiva vrednost krompira police od skroba; on ima visoku energetsku vrednost, budući da pri sagorevanju u organizmu 1 g skroba oslobađa 16,75 kJ energije. Skrob se u organizmu razgrađuje pod dejstvom enzima do glukoze: u usnoj duplji deluje pljuvačna a-amilaza, a u dvanaestopalačnom crevu pankreas na a-amilaza, gde se završava prevođenje skroba u maltozu. Sadržaj proteina u krompiru je nizak (oko 2,1 %) i elektroforezom se razdvajaju u 40 frakcija od kojih glavnu grupu čine protein! molekulskih masa od 17-20 kD. Tuberin je globularni protein koji sadrži sve esencijalne amino kiseline. Po sadržaju lizina i hislidina krompir prevazilazi majčino mleko. Krtola krompira sadrži skoro sve vitamine B grupe u malim količinama, kao i vitamine A,H,C i E. U pepelu krompira nađeno je vise od 20 mineralnih supstancija; makroelemenata kalijuma, fosfora, magnezijuma, gvožđa koji imaju važnu ulogu u metabolizmu kao i mikroelemenata bakra, cinka, magnezijuma, hroma i molibdena. Mineralne supstancije se u najvećoj količini nalaze odmah ispod ljuske. Takođe, krompir sadrži i neke enzime. Krompir se primenjuje u narodnoj medicini za lečenje čira i gastritisa, u farmaceutskoj i prehrambenoj industrial.
PB  - Društvo za ishranu Srbije, Beograd
T2  - Hrana i ishrana
T1  - Potato (Solanum tuberosum L)
T1  - Krompir (Solanum tuberosum L)
VL  - 45
IS  - 1-2
SP  - 10
EP  - 15
UR  - https://hdl.handle.net/21.15107/rcub_cer_161
ER  - 

@article{
author = "Vučetić, Jovan and Gojgić-Cvijović, Gordana and Gopčević, Kristina and Nastasijević, Branislav",
year = "2004",
abstract = "Potato represents almost complete food. Beside carbohydrates, it contains low quantities of lipids and proteins, too. Nutritional value of potato comes from its most important constituent - carbohydrates. Starch is a main complex polysaccharide in potato but it is also a component of cereals, leguminoses vegetables and fruits. Potato contains low quantity of monosaccharide glucose and disaccharide sucrose. Potato has a high nutritional value because of high energy liberated by starch combustion -16,75 kj/1 g of substance. In an organism starch is being hydrolysedby enzyme action: saliva a-amilase and duodenum pancreatic a-amilase induodenum convert starch into maltose units. Potato contajns low quantity of proteins (2,1 %) separable by ele-ctrophoresis into 40 fractions. Main group of proteins are fractions with molecular masses 17-20 kD. All essential am/no acids are present in globular protein tuberin. Potato contains higher amount of aminoacids lysine and histidine than human milk. Potato contains almost all B group vitamins in low quantities, as well as A, H, C and E vitamins. More than 20 minerals were found in potato ash: macroelements potassium, phosphorus, iron and microelements copper, zinc, magnesium, chromium and molybdenum; they have an important role in metabolic pathways. Also, potato contains some enzymes. Potato is used in folk medicine for ulcer and gastritis treatment and in farmaceutical and food industry., Krompir je složena namirnica koja pored ugljenih hidrata sadrži u manjim količinama i proteine i lipide. Hranljiva vrednost krompira police od njegovog najvažnijeg sastojka - ugljenih hidrata. Skrob je glavni složeni ugljeni hidrat krtole krompira ali se on nalazi kao rezervni polisaharid i kod žitarica, mahunarki, u povrću i voću. Od monosaharida i disaharida u krtoli krompira nalaze se u ma/im količinama glukoza i saharoza. Hranljiva vrednost krompira police od skroba; on ima visoku energetsku vrednost, budući da pri sagorevanju u organizmu 1 g skroba oslobađa 16,75 kJ energije. Skrob se u organizmu razgrađuje pod dejstvom enzima do glukoze: u usnoj duplji deluje pljuvačna a-amilaza, a u dvanaestopalačnom crevu pankreas na a-amilaza, gde se završava prevođenje skroba u maltozu. Sadržaj proteina u krompiru je nizak (oko 2,1 %) i elektroforezom se razdvajaju u 40 frakcija od kojih glavnu grupu čine protein! molekulskih masa od 17-20 kD. Tuberin je globularni protein koji sadrži sve esencijalne amino kiseline. Po sadržaju lizina i hislidina krompir prevazilazi majčino mleko. Krtola krompira sadrži skoro sve vitamine B grupe u malim količinama, kao i vitamine A,H,C i E. U pepelu krompira nađeno je vise od 20 mineralnih supstancija; makroelemenata kalijuma, fosfora, magnezijuma, gvožđa koji imaju važnu ulogu u metabolizmu kao i mikroelemenata bakra, cinka, magnezijuma, hroma i molibdena. Mineralne supstancije se u najvećoj količini nalaze odmah ispod ljuske. Takođe, krompir sadrži i neke enzime. Krompir se primenjuje u narodnoj medicini za lečenje čira i gastritisa, u farmaceutskoj i prehrambenoj industrial.",
publisher = "Društvo za ishranu Srbije, Beograd",
journal = "Hrana i ishrana",
title = "Potato (Solanum tuberosum L), Krompir (Solanum tuberosum L)",
volume = "45",
number = "1-2",
pages = "10-15",
url = "https://hdl.handle.net/21.15107/rcub_cer_161"
}

Vučetić, J., Gojgić-Cvijović, G., Gopčević, K.,& Nastasijević, B.. (2004). Potato (Solanum tuberosum L). in Hrana i ishrana
Društvo za ishranu Srbije, Beograd., 45(1-2), 10-15.
https://hdl.handle.net/21.15107/rcub_cer_161

Vučetić J, Gojgić-Cvijović G, Gopčević K, Nastasijević B. Potato (Solanum tuberosum L). in Hrana i ishrana. 2004;45(1-2):10-15.
https://hdl.handle.net/21.15107/rcub_cer_161 .

Vučetić, Jovan, Gojgić-Cvijović, Gordana, Gopčević, Kristina, Nastasijević, Branislav, "Potato (Solanum tuberosum L)" in Hrana i ishrana, 45, no. 1-2 (2004):10-15,
https://hdl.handle.net/21.15107/rcub_cer_161 .

TY  - JOUR
AU  - Vučetić, Jovan
AU  - Gojgić-Cvijović, Gordana
AU  - Gopčević, Kristina
AU  - Izrael, Lidija
PY  - 2000
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5
AB  - In this paper mushrooms as an important food component were described. Their chemical composition: nitrogen compounds, carbohydrates, mineral and organic acids, as well as vitamins, enzymes and aromatic and extractable substances were discussed. Chemical composition of mushrooms was compared with the other foods - some kinds of meat. Also, micro and macroelements contents was presented. The role of mushrooms in medicine was described.
AB  - U radu su opisane gljive (pečurke) kao važan sastojak ishrane. Naveden je njihov hemijski sastav: azotne supstance, ugljeni hidrati, mineralne i organske kiseline, vitamini, enzimi, aromatične i ekstraktivne supstance. Dat je pregled zastupljenosti mikro- i makroelemenata u gljivama. Ukazano je i na ulogu gljiva u medicini.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Hemijski pregled
T1  - Mushrooms: An important food product
T1  - Jestive gljive (pečurke) - cenjen proizvod ishrane
VL  - 41
IS  - 2
SP  - 51
EP  - 55
UR  - https://hdl.handle.net/21.15107/rcub_cer_5
ER  - 

@article{
author = "Vučetić, Jovan and Gojgić-Cvijović, Gordana and Gopčević, Kristina and Izrael, Lidija",
year = "2000",
abstract = "In this paper mushrooms as an important food component were described. Their chemical composition: nitrogen compounds, carbohydrates, mineral and organic acids, as well as vitamins, enzymes and aromatic and extractable substances were discussed. Chemical composition of mushrooms was compared with the other foods - some kinds of meat. Also, micro and macroelements contents was presented. The role of mushrooms in medicine was described., U radu su opisane gljive (pečurke) kao važan sastojak ishrane. Naveden je njihov hemijski sastav: azotne supstance, ugljeni hidrati, mineralne i organske kiseline, vitamini, enzimi, aromatične i ekstraktivne supstance. Dat je pregled zastupljenosti mikro- i makroelemenata u gljivama. Ukazano je i na ulogu gljiva u medicini.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Hemijski pregled",
title = "Mushrooms: An important food product, Jestive gljive (pečurke) - cenjen proizvod ishrane",
volume = "41",
number = "2",
pages = "51-55",
url = "https://hdl.handle.net/21.15107/rcub_cer_5"
}

Vučetić, J., Gojgić-Cvijović, G., Gopčević, K.,& Izrael, L.. (2000). Mushrooms: An important food product. in Hemijski pregled
Srpsko hemijsko društvo, Beograd., 41(2), 51-55.
https://hdl.handle.net/21.15107/rcub_cer_5

Vučetić J, Gojgić-Cvijović G, Gopčević K, Izrael L. Mushrooms: An important food product. in Hemijski pregled. 2000;41(2):51-55.
https://hdl.handle.net/21.15107/rcub_cer_5 .

Vučetić, Jovan, Gojgić-Cvijović, Gordana, Gopčević, Kristina, Izrael, Lidija, "Mushrooms: An important food product" in Hemijski pregled, 41, no. 2 (2000):51-55,
https://hdl.handle.net/21.15107/rcub_cer_5 .