@conference{
author = "Marinković, Vesna and Lugonja, Nikoleta and Jesic, Milos and Hajdarpasic, Vesna and Sekulovic, Gordana",
year = "2023",
abstract = "Background and Aims:
Human milk (HM) feeding has an important role in prevention of oxydative stress in preterm
infants. Human milk is a complex biological fluid with an antioxidative function. Antioxidative
enzymes present in HM are superoxid dismutase (SOD), glutatione peroxidase (GSH-Px) and
glutatione reductase (GR).
Evaluation of antioxidative enzymes (SOD, GSH-Px, GR) in HM after heat treatment, ie
pasteurisation of donor HM previously freezed for 7 days in HM bank, using spectrophotometric
methods.
Methods:
Cohort study enrolled 30 mothers of preterm neonates (birth before 37 weeks of gestational age)
that established lactation. Antioxidative activity of enzymes in milk samples before and after the
heat treatment was measured with spectrophotometric methods. Study protocol was approved by
Ethical Comittee of Institute for neonatology, all mothers gave their written consent prior to
participation.
Study was supported by Ministry of education, science and tehchnological development, Serbia.
Results:
SOD, GSH-Px and GR acitivity was significantly higher in fresh mature milk samples compared
to mature, frozen for seven days and then pasteurised, milk of mothers of preterm infants
(p<0,001).
Conclusions:
Process of heat treatment and/or storage of mature milk of mothers of preterm infants reduce
enzyme acitivity of HM, thereby decreasing total antioxidative capacity. This implies that it
would be optimal to feed the preterm infants with fresh fortified HM whenever possible.",
publisher = "Kenes Group",
journal = "10th International Conference on Nutrition and Growth, 30 March - 1 April 2023 London, UK",
title = "Impact of freezing and pasteurization on antioxidative enzymes in milk of preterm infants' mothers",
volume = "EP017/#126",
url = "https://hdl.handle.net/21.15107/rcub_cer_7251"
}