TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Pezo, Lato
AU  - Zeremski, Tijana
AU  - Ovuka, Jelena S.
AU  - Sikora, Vladimir Š.
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4601
AB  - Marrubium vulgare is a cosmopolitan medicinal plant from the Lamiaceae family, which produces structurally highly diverse groups of secondary metabolites. A total of 160 compounds were determined in the volatiles from Serbia during two investigated years (2019 and 2020). The main components were E-caryophyllene, followed by germacrene D, α-humulene and α-copaene. All these compounds are from sesquiterpene hydrocarbons class which was dominant in both investigated years. This variation in volatiles composition could be a consequence of weather conditions, as in the case of other aromatic plants. According to the unrooted cluster tree with 37 samples of Marrubium sp. volatiles from literature and average values from this study, it could be said that there are several chemotypes: E-caryophyllene, β-bisabolene, α-pinene, β-farnesene, E-caryophyllene + caryophyllene oxide chemotype, and diverse (unclassified) chemotypes. However, occurring polymorphism could be consequence of adaptation to grow in different environment, especially ecological conditions such as humidity, temperature and altitude, as well as hybridization strongly affected the chemotypes. In addition, this paper aimed to obtain validated models for prediction of retention indices (RIs) of compounds isolated from M. vulgare volatiles. A total of 160 experimentally obtained RIs of volatile compounds was used to build the prediction models. The coefficients of determination were 0.956 and 0.964, demonstrating that these models could be used for predicting RIs, due to low prediction error and high r2 .
PB  - MDPI
T2  - Plants
T1  - Chemical characterization of marrubium vulgare volatiles from Serbia
VL  - 10
IS  - 3
SP  - 600
DO  - 10.3390/plants10030600
ER  - 

@article{
author = "Aćimović, Milica G. and Ivanović, Stefan and Simić, Katarina and Pezo, Lato and Zeremski, Tijana and Ovuka, Jelena S. and Sikora, Vladimir Š.",
year = "2021",
abstract = "Marrubium vulgare is a cosmopolitan medicinal plant from the Lamiaceae family, which produces structurally highly diverse groups of secondary metabolites. A total of 160 compounds were determined in the volatiles from Serbia during two investigated years (2019 and 2020). The main components were E-caryophyllene, followed by germacrene D, α-humulene and α-copaene. All these compounds are from sesquiterpene hydrocarbons class which was dominant in both investigated years. This variation in volatiles composition could be a consequence of weather conditions, as in the case of other aromatic plants. According to the unrooted cluster tree with 37 samples of Marrubium sp. volatiles from literature and average values from this study, it could be said that there are several chemotypes: E-caryophyllene, β-bisabolene, α-pinene, β-farnesene, E-caryophyllene + caryophyllene oxide chemotype, and diverse (unclassified) chemotypes. However, occurring polymorphism could be consequence of adaptation to grow in different environment, especially ecological conditions such as humidity, temperature and altitude, as well as hybridization strongly affected the chemotypes. In addition, this paper aimed to obtain validated models for prediction of retention indices (RIs) of compounds isolated from M. vulgare volatiles. A total of 160 experimentally obtained RIs of volatile compounds was used to build the prediction models. The coefficients of determination were 0.956 and 0.964, demonstrating that these models could be used for predicting RIs, due to low prediction error and high r2 .",
publisher = "MDPI",
journal = "Plants",
title = "Chemical characterization of marrubium vulgare volatiles from Serbia",
volume = "10",
number = "3",
pages = "600",
doi = "10.3390/plants10030600"
}

Aćimović, M. G., Ivanović, S., Simić, K., Pezo, L., Zeremski, T., Ovuka, J. S.,& Sikora, V. Š.. (2021). Chemical characterization of marrubium vulgare volatiles from Serbia. in Plants
MDPI., 10(3), 600.
https://doi.org/10.3390/plants10030600

Aćimović MG, Ivanović S, Simić K, Pezo L, Zeremski T, Ovuka JS, Sikora VŠ. Chemical characterization of marrubium vulgare volatiles from Serbia. in Plants. 2021;10(3):600.
doi:10.3390/plants10030600 .

Aćimović, Milica G., Ivanović, Stefan, Simić, Katarina, Pezo, Lato, Zeremski, Tijana, Ovuka, Jelena S., Sikora, Vladimir Š., "Chemical characterization of marrubium vulgare volatiles from Serbia" in Plants, 10, no. 3 (2021):600,
https://doi.org/10.3390/plants10030600 . .