Microcystins: Potential risk factors in carcinogenesis of primary liver cancer in Serbia
2011
Authors
Drobac, DamjanaSvirčev, Zorica
Tokodi, Nada
Vidović, Milka
Baltić, Vladimir
Božić-Krstić, Verica
Lazić, Dragana
Pavlica, Tatjana
Article (Published version)
Metadata
Show full item recordAbstract
The Primary Liver Carcinoma (PLC) is one of the most common malignant diseases in the world. In Central Serbia during the period from 2000 to 2006 the average incidence was 16.9/100 000 that complies to the European epidemiology. The main risk factors for PLC are considered to be cirrhosis of liver and viral chronic Hepatitis B and C. The goal of this research was to analyze epidemiological data of these diseases and to state the correlation between PLC, liver cirrhosis and Hepatitis B and C in Serbia. During the research period of 6 years the correlations between PLC and the corresponding risk factors were negative. For this reason it was necessary to examine other risk factors. The high incidence of PLC in Nišavski, Toplički and Šumadijski region correlate with emerging blooms of Cyanobacteria in water reservoirs supplying these areas with drinking water. Since we examined only 7 years span and have no completed cyanotoxin analysis, it is necessary to complete more research in this f...ield. The identification of cyanotoxins as risk factors that contribute to the development of liver cancer will help in the prevention of this disease.
Keywords:
PLC / Central Serbia / rick factors / cirrhosis / HBV / HCV / microcystinSource:
Geographica Pannonica, 2011, 15, 3, 70-80Publisher:
- University of Novi Sad, Department of Geography, Tourism and Hotel Management
Funding / projects:
- Transformation of Serbian Geospace - lessons from the past, contemporary problems and possible solutions (RS-MESTD-Basic Research (BR or ON)-176020)
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Institution/Community
IHTMTY - JOUR AU - Drobac, Damjana AU - Svirčev, Zorica AU - Tokodi, Nada AU - Vidović, Milka AU - Baltić, Vladimir AU - Božić-Krstić, Verica AU - Lazić, Dragana AU - Pavlica, Tatjana PY - 2011 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/874 AB - The Primary Liver Carcinoma (PLC) is one of the most common malignant diseases in the world. In Central Serbia during the period from 2000 to 2006 the average incidence was 16.9/100 000 that complies to the European epidemiology. The main risk factors for PLC are considered to be cirrhosis of liver and viral chronic Hepatitis B and C. The goal of this research was to analyze epidemiological data of these diseases and to state the correlation between PLC, liver cirrhosis and Hepatitis B and C in Serbia. During the research period of 6 years the correlations between PLC and the corresponding risk factors were negative. For this reason it was necessary to examine other risk factors. The high incidence of PLC in Nišavski, Toplički and Šumadijski region correlate with emerging blooms of Cyanobacteria in water reservoirs supplying these areas with drinking water. Since we examined only 7 years span and have no completed cyanotoxin analysis, it is necessary to complete more research in this field. The identification of cyanotoxins as risk factors that contribute to the development of liver cancer will help in the prevention of this disease. PB - University of Novi Sad, Department of Geography, Tourism and Hotel Management T2 - Geographica Pannonica T1 - Microcystins: Potential risk factors in carcinogenesis of primary liver cancer in Serbia VL - 15 IS - 3 SP - 70 EP - 80 DO - 10.5937/GeoPan1103070D ER -
@article{ author = "Drobac, Damjana and Svirčev, Zorica and Tokodi, Nada and Vidović, Milka and Baltić, Vladimir and Božić-Krstić, Verica and Lazić, Dragana and Pavlica, Tatjana", year = "2011", abstract = "The Primary Liver Carcinoma (PLC) is one of the most common malignant diseases in the world. In Central Serbia during the period from 2000 to 2006 the average incidence was 16.9/100 000 that complies to the European epidemiology. The main risk factors for PLC are considered to be cirrhosis of liver and viral chronic Hepatitis B and C. The goal of this research was to analyze epidemiological data of these diseases and to state the correlation between PLC, liver cirrhosis and Hepatitis B and C in Serbia. During the research period of 6 years the correlations between PLC and the corresponding risk factors were negative. For this reason it was necessary to examine other risk factors. The high incidence of PLC in Nišavski, Toplički and Šumadijski region correlate with emerging blooms of Cyanobacteria in water reservoirs supplying these areas with drinking water. Since we examined only 7 years span and have no completed cyanotoxin analysis, it is necessary to complete more research in this field. The identification of cyanotoxins as risk factors that contribute to the development of liver cancer will help in the prevention of this disease.", publisher = "University of Novi Sad, Department of Geography, Tourism and Hotel Management", journal = "Geographica Pannonica", title = "Microcystins: Potential risk factors in carcinogenesis of primary liver cancer in Serbia", volume = "15", number = "3", pages = "70-80", doi = "10.5937/GeoPan1103070D" }
Drobac, D., Svirčev, Z., Tokodi, N., Vidović, M., Baltić, V., Božić-Krstić, V., Lazić, D.,& Pavlica, T.. (2011). Microcystins: Potential risk factors in carcinogenesis of primary liver cancer in Serbia. in Geographica Pannonica University of Novi Sad, Department of Geography, Tourism and Hotel Management., 15(3), 70-80. https://doi.org/10.5937/GeoPan1103070D
Drobac D, Svirčev Z, Tokodi N, Vidović M, Baltić V, Božić-Krstić V, Lazić D, Pavlica T. Microcystins: Potential risk factors in carcinogenesis of primary liver cancer in Serbia. in Geographica Pannonica. 2011;15(3):70-80. doi:10.5937/GeoPan1103070D .
Drobac, Damjana, Svirčev, Zorica, Tokodi, Nada, Vidović, Milka, Baltić, Vladimir, Božić-Krstić, Verica, Lazić, Dragana, Pavlica, Tatjana, "Microcystins: Potential risk factors in carcinogenesis of primary liver cancer in Serbia" in Geographica Pannonica, 15, no. 3 (2011):70-80, https://doi.org/10.5937/GeoPan1103070D . .