Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm
Samo za registrovane korisnike
2023
Autori
Aćimović, MilicaSemerdijeva, Ivanka
Zheljazkov, Valtcho D.
Rat, Milica
Stanković Jeremić, Jovana
Lončar, Biljana
Vukić, Vladimir
Radovanović, Katarina
Gavarić, Neda
Pezo, Lato
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile. On the other hand, the results from Bulgaria show an evident chemical diversification within the A. clypeolata species, as 1,8-cineole (23.2%), camphor (5.0%) and borneol ...(8.9%) prevailed in the EO of the studied samples collected from Ivaylovgrad, while borneol (22.6%), β-eudesmol (12.7%) and elemol (7.8%) were the main ones in the EO from Dobrostan. In sillico analysis revealed the high anti-inflammatory potential of A. clypeolata, which may be highly diverse depending on the population and active compounds it contains.
Ključne reči:
Essential oil / PCA / Correlation diagram / Unrooted cluster tree / Endemic species / Anti-inflammatory activityIzvor:
Biochemical Systematics and Ecology, 2023, 110, 104679-Izdavač:
- Elsevier BV
Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200032 (Naučni institut za ratarstvo i povrtarstvo, Novi Sad) (RS-MESTD-inst-2020-200032)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200114 (Univerzitet u Novom Sadu, Medicinski fakultet) (RS-MESTD-inst-2020-200114)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200134 (Univerzitet u Novom Sadu, Tehnološki fakultet) (RS-MESTD-inst-2020-200134)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200051 (Institut za opštu i fizičku hemiju, Beograd) (RS-MESTD-inst-2020-200051)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200026 (Univerzitet u Beogradu, Institut za hemiju, tehnologiju i metalurgiju - IHTM) (RS-MESTD-inst-2020-200026)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200125 (Univerzitet u Novom Sadu, Prirodno-matematički fakultet) (RS-MESTD-inst-2020-200125)
DOI: 10.1016/j.bse.2023.104679
ISSN: 0305-1978
WoS: 001026636300001
Scopus: 2-s2.0-85164251087
Institucija/grupa
IHTMTY - JOUR AU - Aćimović, Milica AU - Semerdijeva, Ivanka AU - Zheljazkov, Valtcho D. AU - Rat, Milica AU - Stanković Jeremić, Jovana AU - Lončar, Biljana AU - Vukić, Vladimir AU - Radovanović, Katarina AU - Gavarić, Neda AU - Pezo, Lato PY - 2023 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/6679 AB - This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile. On the other hand, the results from Bulgaria show an evident chemical diversification within the A. clypeolata species, as 1,8-cineole (23.2%), camphor (5.0%) and borneol (8.9%) prevailed in the EO of the studied samples collected from Ivaylovgrad, while borneol (22.6%), β-eudesmol (12.7%) and elemol (7.8%) were the main ones in the EO from Dobrostan. In sillico analysis revealed the high anti-inflammatory potential of A. clypeolata, which may be highly diverse depending on the population and active compounds it contains. PB - Elsevier BV T2 - Biochemical Systematics and Ecology T1 - Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm VL - 110 SP - 104679 DO - 10.1016/j.bse.2023.104679 ER -
@article{ author = "Aćimović, Milica and Semerdijeva, Ivanka and Zheljazkov, Valtcho D. and Rat, Milica and Stanković Jeremić, Jovana and Lončar, Biljana and Vukić, Vladimir and Radovanović, Katarina and Gavarić, Neda and Pezo, Lato", year = "2023", abstract = "This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile. On the other hand, the results from Bulgaria show an evident chemical diversification within the A. clypeolata species, as 1,8-cineole (23.2%), camphor (5.0%) and borneol (8.9%) prevailed in the EO of the studied samples collected from Ivaylovgrad, while borneol (22.6%), β-eudesmol (12.7%) and elemol (7.8%) were the main ones in the EO from Dobrostan. In sillico analysis revealed the high anti-inflammatory potential of A. clypeolata, which may be highly diverse depending on the population and active compounds it contains.", publisher = "Elsevier BV", journal = "Biochemical Systematics and Ecology", title = "Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm", volume = "110", pages = "104679", doi = "10.1016/j.bse.2023.104679" }
Aćimović, M., Semerdijeva, I., Zheljazkov, V. D., Rat, M., Stanković Jeremić, J., Lončar, B., Vukić, V., Radovanović, K., Gavarić, N.,& Pezo, L.. (2023). Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm. in Biochemical Systematics and Ecology Elsevier BV., 110, 104679. https://doi.org/10.1016/j.bse.2023.104679
Aćimović M, Semerdijeva I, Zheljazkov VD, Rat M, Stanković Jeremić J, Lončar B, Vukić V, Radovanović K, Gavarić N, Pezo L. Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm. in Biochemical Systematics and Ecology. 2023;110:104679. doi:10.1016/j.bse.2023.104679 .
Aćimović, Milica, Semerdijeva, Ivanka, Zheljazkov, Valtcho D., Rat, Milica, Stanković Jeremić, Jovana, Lončar, Biljana, Vukić, Vladimir, Radovanović, Katarina, Gavarić, Neda, Pezo, Lato, "Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm" in Biochemical Systematics and Ecology, 110 (2023):104679, https://doi.org/10.1016/j.bse.2023.104679 . .