Detection of target substances using affinitz based MEMS/NEMS sensors: a problem of selectivity
Konferencijski prilog (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Affinity-based micro/nanosensors intended for detection of various chemical or biological agents in a liquid or gaseous environment have a great potential for both civilian and military applications. Selective detection of a target
substance is based on highly specific binding of its particles to the functionalized surface of the sensing element. However, samples taken from the environment often contain substances other than the target, which can also bind with
a certain affinity to the same functionalizing layer or binding sites, thus affecting the sensor's response. In this paper we analyze the influence of limited selectivity of a sensor on its time response. The results show that binding of a non-target substance can cause a significant change in both the equilibrium value and the rate of the sensor's response. The presented analysis enables improvement of accuracy of determination of the target substance concentration in detection methods based on time domain measurements of the... sensor's output signal. It is also useful for development of methods for simultaneous detection of multiple substances.
Ključne reči:
Micro/nanoelectromechanical sensor / chemical agent / biological agent / sensor selectivityIzvor:
Proceedings - 5th International Scientific Conference on Defensive Technologies OTEH 2012, 18 – 19 september 2012, Belgrade, 2012, 398-401Izdavač:
- Belgrade : The Military Technical Institute
Finansiranje / projekti:
- Mikro, nano-sistemi i senzori za primenu u elektroprivredi, procesnoj industriji i zaštiti životne sredine (RS-MESTD-Technological Development (TD or TR)-32008)
Institucija/grupa
IHTMTY - CONF AU - Jokić, Ivana AU - Radulović, Katarina AU - Vasiljević-Radović, Dana PY - 2012 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/5738 AB - Affinity-based micro/nanosensors intended for detection of various chemical or biological agents in a liquid or gaseous environment have a great potential for both civilian and military applications. Selective detection of a target substance is based on highly specific binding of its particles to the functionalized surface of the sensing element. However, samples taken from the environment often contain substances other than the target, which can also bind with a certain affinity to the same functionalizing layer or binding sites, thus affecting the sensor's response. In this paper we analyze the influence of limited selectivity of a sensor on its time response. The results show that binding of a non-target substance can cause a significant change in both the equilibrium value and the rate of the sensor's response. The presented analysis enables improvement of accuracy of determination of the target substance concentration in detection methods based on time domain measurements of the sensor's output signal. It is also useful for development of methods for simultaneous detection of multiple substances. PB - Belgrade : The Military Technical Institute C3 - Proceedings - 5th International Scientific Conference on Defensive Technologies OTEH 2012, 18 – 19 september 2012, Belgrade T1 - Detection of target substances using affinitz based MEMS/NEMS sensors: a problem of selectivity SP - 398 EP - 401 UR - https://hdl.handle.net/21.15107/rcub_cer_5738 ER -
@conference{ author = "Jokić, Ivana and Radulović, Katarina and Vasiljević-Radović, Dana", year = "2012", abstract = "Affinity-based micro/nanosensors intended for detection of various chemical or biological agents in a liquid or gaseous environment have a great potential for both civilian and military applications. Selective detection of a target substance is based on highly specific binding of its particles to the functionalized surface of the sensing element. However, samples taken from the environment often contain substances other than the target, which can also bind with a certain affinity to the same functionalizing layer or binding sites, thus affecting the sensor's response. In this paper we analyze the influence of limited selectivity of a sensor on its time response. The results show that binding of a non-target substance can cause a significant change in both the equilibrium value and the rate of the sensor's response. The presented analysis enables improvement of accuracy of determination of the target substance concentration in detection methods based on time domain measurements of the sensor's output signal. It is also useful for development of methods for simultaneous detection of multiple substances.", publisher = "Belgrade : The Military Technical Institute", journal = "Proceedings - 5th International Scientific Conference on Defensive Technologies OTEH 2012, 18 – 19 september 2012, Belgrade", title = "Detection of target substances using affinitz based MEMS/NEMS sensors: a problem of selectivity", pages = "398-401", url = "https://hdl.handle.net/21.15107/rcub_cer_5738" }
Jokić, I., Radulović, K.,& Vasiljević-Radović, D.. (2012). Detection of target substances using affinitz based MEMS/NEMS sensors: a problem of selectivity. in Proceedings - 5th International Scientific Conference on Defensive Technologies OTEH 2012, 18 – 19 september 2012, Belgrade Belgrade : The Military Technical Institute., 398-401. https://hdl.handle.net/21.15107/rcub_cer_5738
Jokić I, Radulović K, Vasiljević-Radović D. Detection of target substances using affinitz based MEMS/NEMS sensors: a problem of selectivity. in Proceedings - 5th International Scientific Conference on Defensive Technologies OTEH 2012, 18 – 19 september 2012, Belgrade. 2012;:398-401. https://hdl.handle.net/21.15107/rcub_cer_5738 .
Jokić, Ivana, Radulović, Katarina, Vasiljević-Radović, Dana, "Detection of target substances using affinitz based MEMS/NEMS sensors: a problem of selectivity" in Proceedings - 5th International Scientific Conference on Defensive Technologies OTEH 2012, 18 – 19 september 2012, Belgrade (2012):398-401, https://hdl.handle.net/21.15107/rcub_cer_5738 .