Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Redox properties of one hydrophobic spin probe 3-(acetoxymethoxy)carbonyl-2,2,5,5-tetramethyl pyrrolidine-N-oxyl (AM-CxP) and corresponding water-soluble compound, 3-carboxy-2,2,5,5-
tetramethyl-pyrrolidine-N-oxyl (3-CxP) were evaluated using electrochemical and EPR methods. The
electrochemical behavior of two spin probes was investigated by cyclic voltammetry in phosphate
buffer solution. The voltammograms of both compounds exhibited a single redox couple related to
nitroxyl radical. EPR spectroscopy revealed that 3-CxP is less susceptible to reduction by Ascorbate
than AM-CxP, nevertheless, both spin probes exhibit a great potential for in vivo applications
Кључне речи:
Redox properties / electrochemistry / EPR / spin probes / kineticsИзвор:
Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry, 2022, 1, 225-228Издавач:
- Društvo fizikohemičara Srbije
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200026 (Универзитет у Београду, Институт за хемију, технологију и металургију - ИХТМ) (RS-MESTD-inst-2020-200026)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200146 (Универзитет у Београду, Факултет за физичку хемију) (RS-MESTD-inst-2020-200146)
Институција/група
IHTMTY - CONF AU - Pavićević, Aleksandra AU - Peyrot, Fabien AU - Mojović, Zorica AU - Mojović, Miloš PY - 2022 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/5550 AB - Redox properties of one hydrophobic spin probe 3-(acetoxymethoxy)carbonyl-2,2,5,5-tetramethyl pyrrolidine-N-oxyl (AM-CxP) and corresponding water-soluble compound, 3-carboxy-2,2,5,5- tetramethyl-pyrrolidine-N-oxyl (3-CxP) were evaluated using electrochemical and EPR methods. The electrochemical behavior of two spin probes was investigated by cyclic voltammetry in phosphate buffer solution. The voltammograms of both compounds exhibited a single redox couple related to nitroxyl radical. EPR spectroscopy revealed that 3-CxP is less susceptible to reduction by Ascorbate than AM-CxP, nevertheless, both spin probes exhibit a great potential for in vivo applications PB - Društvo fizikohemičara Srbije C3 - Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry T1 - Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl VL - 1 SP - 225 EP - 228 UR - https://hdl.handle.net/21.15107/rcub_cer_5550 ER -
@conference{ author = "Pavićević, Aleksandra and Peyrot, Fabien and Mojović, Zorica and Mojović, Miloš", year = "2022", abstract = "Redox properties of one hydrophobic spin probe 3-(acetoxymethoxy)carbonyl-2,2,5,5-tetramethyl pyrrolidine-N-oxyl (AM-CxP) and corresponding water-soluble compound, 3-carboxy-2,2,5,5- tetramethyl-pyrrolidine-N-oxyl (3-CxP) were evaluated using electrochemical and EPR methods. The electrochemical behavior of two spin probes was investigated by cyclic voltammetry in phosphate buffer solution. The voltammograms of both compounds exhibited a single redox couple related to nitroxyl radical. EPR spectroscopy revealed that 3-CxP is less susceptible to reduction by Ascorbate than AM-CxP, nevertheless, both spin probes exhibit a great potential for in vivo applications", publisher = "Društvo fizikohemičara Srbije", journal = "Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry", title = "Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl", volume = "1", pages = "225-228", url = "https://hdl.handle.net/21.15107/rcub_cer_5550" }
Pavićević, A., Peyrot, F., Mojović, Z.,& Mojović, M.. (2022). Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl. in Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry Društvo fizikohemičara Srbije., 1, 225-228. https://hdl.handle.net/21.15107/rcub_cer_5550
Pavićević A, Peyrot F, Mojović Z, Mojović M. Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl. in Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry. 2022;1:225-228. https://hdl.handle.net/21.15107/rcub_cer_5550 .
Pavićević, Aleksandra, Peyrot, Fabien, Mojović, Zorica, Mojović, Miloš, "Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl" in Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry, 1 (2022):225-228, https://hdl.handle.net/21.15107/rcub_cer_5550 .