Приказ основних података о документу
Synthesis and evaluation of several cathechol bioisosteres as potential dopamine receptor ligands
dc.creator | Kostić, Slađana | |
dc.creator | Šoškić, Vukić | |
dc.creator | Joksimović, Jelena | |
dc.date.accessioned | 2021-03-23T08:09:50Z | |
dc.date.available | 2021-03-23T08:09:50Z | |
dc.date.issued | 1991 | |
dc.identifier.issn | 0960-894X | |
dc.identifier.issn | 1464-3405 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/4384 | |
dc.description.abstract | Derivatives of benzimidazole (I), benzimidazolone (II), benzimidazolethione (III), 2,3-dihydroxyquinoxaline (IV) and the noncyclic acetamide (V) and t rifluoroacetamide (VI) of the corresponding 1,2-pheny-lenediamiane were synthesized and tested for DA-ergic activity. III and IV had a moderate affini ty for the D2 receptors of the bovine caudate nucleus. Several potential DA-receptor ligands were synthesized. III and IV expressed the affinity for the D-2 receptor. | sr |
dc.language.iso | en | sr |
dc.publisher | Elsevier | sr |
dc.relation | The Research Science Funds of Serbia, Grant No. 8016. | sr |
dc.rights | restrictedAccess | sr |
dc.source | Bioorganic and Medicinal Chemistry Letters | sr |
dc.subject | dopamine | sr |
dc.subject | drug synthesis | sr |
dc.subject | drug receptor binding | sr |
dc.subject | D-2 receptor | sr |
dc.title | Synthesis and evaluation of several cathechol bioisosteres as potential dopamine receptor ligands | sr |
dc.type | article | sr |
dc.rights.license | ARR | sr |
dc.citation.volume | 1 | |
dc.citation.issue | 8 | |
dc.citation.spage | 403 | |
dc.citation.epage | 406 | |
dc.identifier.doi | 10.1016/S0960-894X(00)80265-6 | |
dc.identifier.scopus | 2-s2.0-0026002989 | |
dc.type.version | publishedVersion | sr |