Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation
Abstract
A number of polysaccharides with β-glycosidic linkage are
widespread in nature in a variety of sources. All have a common structure
and the (1→3)-β-D-glucan backbone is essential. They have attracted attention
over the years because of their bioactive and medicinal properties. In many
cases their functional role is a mystery, in others it is well established. Because
of their insoluble chemical nature, particulate (1→3)-β-D-glucans are not suitable
for many medical applications. Various methods of changing or modifying
the β-D-glucan chemical structure and transforming it to a soluble form have
been published. The β-D-glucan bioactive properties can be affected positively
or negatively by such modifications. This review examines β-glucan sources in
nature, health effects and structure-activity relationships. It presents the current
state of β-D-glucan solubilization methods and discusses their effectiveness and
application possibilities for the future.
Keywords:
glucan / soluble / derivative / solubilization / application / SaccharomycesSource:
Critical Reviews in Biotechnology, 2005, 25, 205-230Publisher:
- England : Taylor & Francis LTD
DOI: 10.1080/07388550500376166
ISSN: 1549-7801; 0738-8551
PubMed: 16419618
WoS: 000234253800003
Scopus: 2-s2.0-28744441263
Collections
Institution/Community
IHTMTY - JOUR AU - Zeković, Đorđe AU - Kwiatkowski, Stefan AU - Vrvić, Miroslav AU - Jakovljević, Dragica AU - Moran, Colm A. PY - 2005 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4084 AB - A number of polysaccharides with β-glycosidic linkage are widespread in nature in a variety of sources. All have a common structure and the (1→3)-β-D-glucan backbone is essential. They have attracted attention over the years because of their bioactive and medicinal properties. In many cases their functional role is a mystery, in others it is well established. Because of their insoluble chemical nature, particulate (1→3)-β-D-glucans are not suitable for many medical applications. Various methods of changing or modifying the β-D-glucan chemical structure and transforming it to a soluble form have been published. The β-D-glucan bioactive properties can be affected positively or negatively by such modifications. This review examines β-glucan sources in nature, health effects and structure-activity relationships. It presents the current state of β-D-glucan solubilization methods and discusses their effectiveness and application possibilities for the future. PB - England : Taylor & Francis LTD T2 - Critical Reviews in Biotechnology T1 - Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation VL - 25 SP - 205 EP - 230 DO - 10.1080/07388550500376166 ER -
@article{ author = "Zeković, Đorđe and Kwiatkowski, Stefan and Vrvić, Miroslav and Jakovljević, Dragica and Moran, Colm A.", year = "2005", abstract = "A number of polysaccharides with β-glycosidic linkage are widespread in nature in a variety of sources. All have a common structure and the (1→3)-β-D-glucan backbone is essential. They have attracted attention over the years because of their bioactive and medicinal properties. In many cases their functional role is a mystery, in others it is well established. Because of their insoluble chemical nature, particulate (1→3)-β-D-glucans are not suitable for many medical applications. Various methods of changing or modifying the β-D-glucan chemical structure and transforming it to a soluble form have been published. The β-D-glucan bioactive properties can be affected positively or negatively by such modifications. This review examines β-glucan sources in nature, health effects and structure-activity relationships. It presents the current state of β-D-glucan solubilization methods and discusses their effectiveness and application possibilities for the future.", publisher = "England : Taylor & Francis LTD", journal = "Critical Reviews in Biotechnology", title = "Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation", volume = "25", pages = "205-230", doi = "10.1080/07388550500376166" }
Zeković, Đ., Kwiatkowski, S., Vrvić, M., Jakovljević, D.,& Moran, C. A.. (2005). Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation. in Critical Reviews in Biotechnology England : Taylor & Francis LTD., 25, 205-230. https://doi.org/10.1080/07388550500376166
Zeković Đ, Kwiatkowski S, Vrvić M, Jakovljević D, Moran CA. Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation. in Critical Reviews in Biotechnology. 2005;25:205-230. doi:10.1080/07388550500376166 .
Zeković, Đorđe, Kwiatkowski, Stefan, Vrvić, Miroslav, Jakovljević, Dragica, Moran, Colm A., "Natural and Modified (1→3)-β-D-Glucans in Health Promotion and Disease Alleviation" in Critical Reviews in Biotechnology, 25 (2005):205-230, https://doi.org/10.1080/07388550500376166 . .