Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)
Abstract
This manuscript describes the first detailed chemical investigation of endemic species Iris adriatica, including isolation and structure elucidation. Chemical analyses of the rhizome CH2Cl2/MeOH (2:1) extract revealed fourteen secondary metabolites, mainly isoflavonoids. Among isoflavonoids, two groups have been found: nigricin-type and tectorigenin-type. Dominant group of the isolated compounds has been nigricin-type isoflavones: nigricin, nigricin-4'-(1-O-beta-D- glucopyranoside) and nigricin-4'-(1-O-beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside) with 2.5, 10 and 1% of the total extract, respectively. Irisxanthone - xanthone C-glucoside, beta-sitosterol, benzophenone and one of its derivatives have also been found. Nigricin-type isoflavonoids and irisxanthone can be considered as possible chemotaxonomic markers for I. adriatica. 5,3',5'-Trimethoxy-6,7-methylenedioxyisoflavone-4'-(1-O-beta-D-glucopyranoside) and benzophenone have been isolated from Iris species for the first time.... Left-hand image of Iris adriatica (Adriatic potato) with redditsh purple flowers
Keywords:
Iris adriatica / rhizome / isoflavonoids / 1D and 2D NMR / HR-EI-MSSource:
Natural Product Research, 2018, 32, 15, 1849-1852Publisher:
- Taylor and Francis Ltd.
Funding / projects:
- Micromorphological, phytochemical and molecular investigations of plants - systematic, ecological and applicative aspects (RS-173029)
- Natural products of wild, cultivated and edible plants: structure and bioactivity determination (RS-172053)
- Matsumae International Foundation
Note:
- Supplementary material: https://cer.ihtm.bg.ac.rs/handle/123456789/4469
Related info:
- Referenced by
https://cer.ihtm.bg.ac.rs/handle/123456789/4469
DOI: 10.1080/14786419.2017.1402309
ISSN: 1478-6419
PubMed: 29126369
WoS: 000436445600015
Scopus: 2-s2.0-85033696429
Collections
Institution/Community
IHTMTY - JOUR AU - Bukvicki, Danka AU - Novaković, Miroslav AU - Ab, Ghani Nurunajah AU - Marin, Petar D. AU - Asakawa, Yoshinori PY - 2018 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2438 AB - This manuscript describes the first detailed chemical investigation of endemic species Iris adriatica, including isolation and structure elucidation. Chemical analyses of the rhizome CH2Cl2/MeOH (2:1) extract revealed fourteen secondary metabolites, mainly isoflavonoids. Among isoflavonoids, two groups have been found: nigricin-type and tectorigenin-type. Dominant group of the isolated compounds has been nigricin-type isoflavones: nigricin, nigricin-4'-(1-O-beta-D- glucopyranoside) and nigricin-4'-(1-O-beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside) with 2.5, 10 and 1% of the total extract, respectively. Irisxanthone - xanthone C-glucoside, beta-sitosterol, benzophenone and one of its derivatives have also been found. Nigricin-type isoflavonoids and irisxanthone can be considered as possible chemotaxonomic markers for I. adriatica. 5,3',5'-Trimethoxy-6,7-methylenedioxyisoflavone-4'-(1-O-beta-D-glucopyranoside) and benzophenone have been isolated from Iris species for the first time. Left-hand image of Iris adriatica (Adriatic potato) with redditsh purple flowers PB - Taylor and Francis Ltd. T2 - Natural Product Research T1 - Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae) VL - 32 IS - 15 SP - 1849 EP - 1852 DO - 10.1080/14786419.2017.1402309 ER -
@article{ author = "Bukvicki, Danka and Novaković, Miroslav and Ab, Ghani Nurunajah and Marin, Petar D. and Asakawa, Yoshinori", year = "2018", abstract = "This manuscript describes the first detailed chemical investigation of endemic species Iris adriatica, including isolation and structure elucidation. Chemical analyses of the rhizome CH2Cl2/MeOH (2:1) extract revealed fourteen secondary metabolites, mainly isoflavonoids. Among isoflavonoids, two groups have been found: nigricin-type and tectorigenin-type. Dominant group of the isolated compounds has been nigricin-type isoflavones: nigricin, nigricin-4'-(1-O-beta-D- glucopyranoside) and nigricin-4'-(1-O-beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside) with 2.5, 10 and 1% of the total extract, respectively. Irisxanthone - xanthone C-glucoside, beta-sitosterol, benzophenone and one of its derivatives have also been found. Nigricin-type isoflavonoids and irisxanthone can be considered as possible chemotaxonomic markers for I. adriatica. 5,3',5'-Trimethoxy-6,7-methylenedioxyisoflavone-4'-(1-O-beta-D-glucopyranoside) and benzophenone have been isolated from Iris species for the first time. Left-hand image of Iris adriatica (Adriatic potato) with redditsh purple flowers", publisher = "Taylor and Francis Ltd.", journal = "Natural Product Research", title = "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)", volume = "32", number = "15", pages = "1849-1852", doi = "10.1080/14786419.2017.1402309" }
Bukvicki, D., Novaković, M., Ab, G. N., Marin, P. D.,& Asakawa, Y.. (2018). Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae). in Natural Product Research Taylor and Francis Ltd.., 32(15), 1849-1852. https://doi.org/10.1080/14786419.2017.1402309
Bukvicki D, Novaković M, Ab GN, Marin PD, Asakawa Y. Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae). in Natural Product Research. 2018;32(15):1849-1852. doi:10.1080/14786419.2017.1402309 .
Bukvicki, Danka, Novaković, Miroslav, Ab, Ghani Nurunajah, Marin, Petar D., Asakawa, Yoshinori, "Secondary metabolites from endemic species Iris adriatica Trinajstic ex Mitic (Iridaceae)" in Natural Product Research, 32, no. 15 (2018):1849-1852, https://doi.org/10.1080/14786419.2017.1402309 . .