Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution
Abstract
Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC.
Keywords:
Sildenafil citrate standard / cystein modified electrode / sensitivity / quantitative analysisSource:
Journal of Electrochemical Science and Engineering, 2018, 8, 2, 163-170Publisher:
- International Association of Physical Chemists (IAPC)
Funding / projects:
- New approach in designing materials for energy conversion and energy storage systems (RS-172060)
- Study of the Synthesis, Structure and Activity of Natural and Synthetic Organic Compounds (RS-172013)
Collections
Institution/Community
IHTMTY - JOUR AU - Lović, Jelena AU - Trišović, Nemanja AU - Antanasijevic, Jelena AU - Avramov Ivić, Milka PY - 2018 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2313 AB - Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC. PB - International Association of Physical Chemists (IAPC) T2 - Journal of Electrochemical Science and Engineering T1 - Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution VL - 8 IS - 2 SP - 163 EP - 170 DO - 10.5599/jese.481 ER -
@article{ author = "Lović, Jelena and Trišović, Nemanja and Antanasijevic, Jelena and Avramov Ivić, Milka", year = "2018", abstract = "Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC.", publisher = "International Association of Physical Chemists (IAPC)", journal = "Journal of Electrochemical Science and Engineering", title = "Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution", volume = "8", number = "2", pages = "163-170", doi = "10.5599/jese.481" }
Lović, J., Trišović, N., Antanasijevic, J.,& Avramov Ivić, M.. (2018). Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution. in Journal of Electrochemical Science and Engineering International Association of Physical Chemists (IAPC)., 8(2), 163-170. https://doi.org/10.5599/jese.481
Lović J, Trišović N, Antanasijevic J, Avramov Ivić M. Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution. in Journal of Electrochemical Science and Engineering. 2018;8(2):163-170. doi:10.5599/jese.481 .
Lović, Jelena, Trišović, Nemanja, Antanasijevic, Jelena, Avramov Ivić, Milka, "Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution" in Journal of Electrochemical Science and Engineering, 8, no. 2 (2018):163-170, https://doi.org/10.5599/jese.481 . .