dc.creator | Bolic, Bojana | |
dc.creator | Mijuskovic, Ana | |
dc.creator | Popovic-Bijelic, Ana | |
dc.creator | Nikolić-Kokić, Aleksandra | |
dc.creator | Spasić, Snežana | |
dc.creator | Blagojevic, Dusko | |
dc.creator | Spasić, Mihajlo | |
dc.creator | Spasojević, Ivan | |
dc.date.accessioned | 2019-01-30T17:47:00Z | |
dc.date.available | 2019-01-30T17:47:00Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 1089-8603 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/1787 | |
dc.description.abstract | Interactions of hydrogen sulfide (HS-/H2S), a reducing signaling species, with superoxide dimutases (SOD) are poorly understood. We applied low-T EPR spectroscopy to examine the effects of HS-/H2S and superoxide radical anion (O-2(-)) on metallocenters of FeSOD, MnSOD, and CuZnSOD. HS-/H2S did not affect FeSOD, whereas active centers of MnSOD and CuZnSOD were open to this agent. Cu2+ was reduced to Cu1+, while manganese appears to be released from MnSOD active center. Untreated and O-2(-) treated FeSOD and MnSOD predominantly show 5 d-electron systems, i.e. Fe3+ and Mn2+. Our study provides new details on the mechanisms of (patho)physiological effects of HS-/H2S. | en |
dc.publisher | Academic Press Inc Elsevier Science, San Diego | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173014/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41005/RS// | |
dc.rights | restrictedAccess | |
dc.source | Nitric Oxide-Biology and Chemistry | |
dc.subject | Superoxide dismutase | en |
dc.subject | EPR | en |
dc.subject | H2S | en |
dc.subject | Iron | en |
dc.subject | Manganese | en |
dc.subject | Copper | en |
dc.title | Reactions of superoxide dismutases with HS-/H2S and superoxide radical anion: An in vitro EPR study | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Спасић, Снежана; Николиц-Кокиц, Aлександра; Благојевиц, Дуско; Спасојевиц, Иван; Болиц, Бојана; Мијусковиц, Aна; Поповиц-Бијелиц, Aна; Спасиц, Михајло Б; | |
dc.citation.volume | 51 | |
dc.citation.spage | 19 | |
dc.citation.epage | 23 | |
dc.citation.other | 51: 19-23 | |
dc.citation.rank | M22 | |
dc.description.other | Accepted version: [http://cer.ihtm.bg.ac.rs/handle/123456789/3187] | |
dc.identifier.pmid | 26436856 | |
dc.identifier.doi | 10.1016/j.niox.2015.09.008 | |
dc.identifier.scopus | 2-s2.0-84944719548 | |
dc.identifier.wos | 000366065100003 | |
dc.type.version | publishedVersion | |