Analysis of human exhaled breath in a population of young volunteers
2014
Аутори
Zarić, BožidarkaPetrović, Srđan
Bjekic, Milan
Rajic, Ivana
Popović, Aleksandar R.
Đorđević, Dragana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Analysis of volatile organic compounds (VOCs) in human breath can provide information about the current physiological state of an individual, such as clinical conditions and exposure to exogenous pollutants. The blood-borne VOCs present in exhaled breath offer the possibility of exploring physiological and pathological processes in a noninvasive way. However, the field of exhaled breath analysis is still in its infancy. We undertook this study in order to define inter-individual variation and common compounds in breath VOCs of 48 young human volunteers. Alveolar breath samples were analyzed by automated thermal desorption, gas chromatography with flame ionization detector (FID) and electron capture detector (ECD) using SUPELCO standards with 66 compounds. Predominant compounds in the alveolar breath of analyzed subjects are ethylbenzene, 1-ethyl-4-methylbenzene, 1,2,4-trimethylbenzene and 1,3,5-trimethylbenzene (over 50% of the subjects). Isopropyl alcohol, propylene, acetone, ethanol ...were found as well. We detected substituted compounds in exhaled breath.
Кључне речи:
alveolar breath / volatile organic compounds / exhaled breath condensate / gas chromatographyИзвор:
Archives of Biological Sciences, 2014, 66, 4, 1529-1538Издавач:
- Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd
Финансирање / пројекти:
DOI: 10.2298/ABS1404529Z
ISSN: 0354-4664
WoS: 000346477900027
Scopus: 2-s2.0-84921629917
Институција/група
IHTMTY - JOUR AU - Zarić, Božidarka AU - Petrović, Srđan AU - Bjekic, Milan AU - Rajic, Ivana AU - Popović, Aleksandar R. AU - Đorđević, Dragana PY - 2014 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/1475 AB - Analysis of volatile organic compounds (VOCs) in human breath can provide information about the current physiological state of an individual, such as clinical conditions and exposure to exogenous pollutants. The blood-borne VOCs present in exhaled breath offer the possibility of exploring physiological and pathological processes in a noninvasive way. However, the field of exhaled breath analysis is still in its infancy. We undertook this study in order to define inter-individual variation and common compounds in breath VOCs of 48 young human volunteers. Alveolar breath samples were analyzed by automated thermal desorption, gas chromatography with flame ionization detector (FID) and electron capture detector (ECD) using SUPELCO standards with 66 compounds. Predominant compounds in the alveolar breath of analyzed subjects are ethylbenzene, 1-ethyl-4-methylbenzene, 1,2,4-trimethylbenzene and 1,3,5-trimethylbenzene (over 50% of the subjects). Isopropyl alcohol, propylene, acetone, ethanol were found as well. We detected substituted compounds in exhaled breath. PB - Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd T2 - Archives of Biological Sciences T1 - Analysis of human exhaled breath in a population of young volunteers VL - 66 IS - 4 SP - 1529 EP - 1538 DO - 10.2298/ABS1404529Z ER -
@article{ author = "Zarić, Božidarka and Petrović, Srđan and Bjekic, Milan and Rajic, Ivana and Popović, Aleksandar R. and Đorđević, Dragana", year = "2014", abstract = "Analysis of volatile organic compounds (VOCs) in human breath can provide information about the current physiological state of an individual, such as clinical conditions and exposure to exogenous pollutants. The blood-borne VOCs present in exhaled breath offer the possibility of exploring physiological and pathological processes in a noninvasive way. However, the field of exhaled breath analysis is still in its infancy. We undertook this study in order to define inter-individual variation and common compounds in breath VOCs of 48 young human volunteers. Alveolar breath samples were analyzed by automated thermal desorption, gas chromatography with flame ionization detector (FID) and electron capture detector (ECD) using SUPELCO standards with 66 compounds. Predominant compounds in the alveolar breath of analyzed subjects are ethylbenzene, 1-ethyl-4-methylbenzene, 1,2,4-trimethylbenzene and 1,3,5-trimethylbenzene (over 50% of the subjects). Isopropyl alcohol, propylene, acetone, ethanol were found as well. We detected substituted compounds in exhaled breath.", publisher = "Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd", journal = "Archives of Biological Sciences", title = "Analysis of human exhaled breath in a population of young volunteers", volume = "66", number = "4", pages = "1529-1538", doi = "10.2298/ABS1404529Z" }
Zarić, B., Petrović, S., Bjekic, M., Rajic, I., Popović, A. R.,& Đorđević, D.. (2014). Analysis of human exhaled breath in a population of young volunteers. in Archives of Biological Sciences Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd., 66(4), 1529-1538. https://doi.org/10.2298/ABS1404529Z
Zarić B, Petrović S, Bjekic M, Rajic I, Popović AR, Đorđević D. Analysis of human exhaled breath in a population of young volunteers. in Archives of Biological Sciences. 2014;66(4):1529-1538. doi:10.2298/ABS1404529Z .
Zarić, Božidarka, Petrović, Srđan, Bjekic, Milan, Rajic, Ivana, Popović, Aleksandar R., Đorđević, Dragana, "Analysis of human exhaled breath in a population of young volunteers" in Archives of Biological Sciences, 66, no. 4 (2014):1529-1538, https://doi.org/10.2298/ABS1404529Z . .