Приказ основних података о документу
Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization
dc.creator | Mandić, Boris | |
dc.creator | Simić, Milena R. | |
dc.creator | Vučković, Ivan | |
dc.creator | Vujisić, Ljubodrag V. | |
dc.creator | Novaković, Miroslav | |
dc.creator | Trifunović, Snežana | |
dc.creator | Nikolic-Mandic, Snezana D. | |
dc.creator | Tešević, Vele | |
dc.creator | Vajs, Vlatka | |
dc.creator | Milosavljević, Slobodan | |
dc.date.accessioned | 2019-01-30T17:35:27Z | |
dc.date.available | 2019-01-30T17:35:27Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 1420-3049 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/1241 | |
dc.description.abstract | The examination of the aerial parts, roots, and seeds of the endemic plant Rindera umbellata is reported in this paper for the first time. Phytochemical investigation of R. umbellata led to the isolation and characterization of ten pyrrolizidine alkaloids and eleven fatty acids in the form of triglycerides. Pyrrolizidine alkaloids 1-9 were found in the aerial parts, 7 and 8 in the roots, and 6-10, together with eleven fatty acids, in the seeds of this plant species. The structures of compounds 1-10 were established based on spectroscopic studies (H-1- and C-13-NMR, 2D NMR, IR and CI-MS). After trans-esterification, methyl esters of the fatty acids were analyzed using GC-MS. The effect of lindelofine-N-oxide (7) on tubulin polymerization was determined. | en |
dc.publisher | MDPI | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS// | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | Molecules | |
dc.subject | Rindera umbellata | en |
dc.subject | pyrrolizidine alkaloids | en |
dc.subject | fatty acids | en |
dc.subject | tubulin polymerization | en |
dc.title | Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization | en |
dc.type | article | |
dc.rights.license | BY | |
dcterms.abstract | Вујисиц, Љубодраг В.; Вајс, Влатка В.; Тесевиц, Веле В.; Мандиц, Борис М.; Николиц-Мандиц, Снезана Д.; Симиц, Милена Р.; Трифуновиц, Снезана С.; Новаковић, Мирослав; Милосављевиц, Слободан М.; Вуцковиц, Иван М.; | |
dc.citation.volume | 18 | |
dc.citation.issue | 9 | |
dc.citation.spage | 10694 | |
dc.citation.epage | 10706 | |
dc.citation.other | 18(9): 10694-10706 | |
dc.citation.rank | M22 | |
dc.identifier.pmid | 24005964 | |
dc.identifier.doi | 10.3390/molecules180910694 | |
dc.identifier.fulltext | https://cer.ihtm.bg.ac.rs//bitstream/id/7753/1239.pdf | |
dc.identifier.scopus | 2-s2.0-84885140370 | |
dc.identifier.wos | 000330306600041 | |
dc.type.version | publishedVersion |