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dc.creatorNovaković, Irena
dc.creatorPenjišević, Jelena
dc.creatorŠukalović, Vladimir
dc.creatorAndrić, Deana
dc.creatorRoglić, Goran
dc.creatorKostić Rajačić, Slađana
dc.date.accessioned2019-01-30T17:29:32Z
dc.date.available2019-01-30T17:29:32Z
dc.date.issued2012
dc.identifier.issn0354-4664
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/963
dc.description.abstractThe derivatives of cinnamic acid and N-arylpiperazine show antibacterial activity. In this work the potential synergistic effect of cinnamyl derivatives of arylpiperazine in selected bacteria was investigated. The antibacterial activities of the derivatives were evaluated against Gram-positive bacteria: Staphylococcus aureus, Streptosporangium longisporum, Sarcina lutea, Micrococcus flavus, Clostridium sporogenes and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa, Salmonella enteritidis and Proteus vulgaris by the disc diffusion method. The minimum inhibitory concentration (MIC) against the selected bacteria was determined for all compounds that showed activity in the disc diffusion method. The majority of the investigated compounds displayed in vitro antibacterial activity. The effect of the type and structure of the substituent on the aromatic ring on the antibacterial activity is discussed. It was found that two derivatives expressed activity toward S. longisporum and P. aeruginosa that was almost as strong as that of amikacin.en
dc.publisherInst Bioloska Istrazivanja Sinisa Stankovic, Beograd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172032/RS//
dc.rightsopenAccess
dc.sourceArchives of Biological Sciences
dc.subjectarylpiperazineen
dc.subjectantibacterial activityen
dc.subjectminimum inhibitory concentrationen
dc.subjectin vitro studiesen
dc.titleInvestigation of antibacterial activity of cinnamyl derivatives of arylpiperazineen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractШукаловић, Владимир; Aндриц, Деана; Костић Рајачић, Слађана; Новаковић, Ирена; Пењишевић, Јелена; Роглиц, Г.;
dc.citation.volume64
dc.citation.issue1
dc.citation.spage15
dc.citation.epage20
dc.citation.other64(1): 15-20
dc.citation.rankM23
dc.identifier.doi10.2298/ABS1201015N
dc.identifier.rcubConv_2796
dc.identifier.fulltexthttp://cer.ihtm.bg.ac.rs//bitstream/id/9534/961.pdf
dc.identifier.scopus2-s2.0-84863747149
dc.identifier.wos000303697400003
dc.type.versionpublishedVersion


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