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dc.creatorAljančić, Ivana
dc.creatorPesic, Milica
dc.creatorMilosavljević, Slobodan
dc.creatorTodorović, Nina
dc.creatorJadranin, Milka
dc.creatorMiosavljevic, Goran
dc.creatorPovrenovic, Dragan
dc.creatorBankovic, Jasna
dc.creatorTanic, Nikola
dc.creatorMarkovic, Ivanka D.
dc.creatorRuzdijic, Sabera
dc.creatorVajs, Vlatka
dc.creatorTešević, Vele
dc.date.accessioned2019-01-30T17:27:54Z
dc.date.available2019-01-30T17:27:54Z
dc.date.issued2011
dc.identifier.issn0163-3864
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/883
dc.description.abstractFrom the Montenegrin spurge Euphorbia dendroides, seven new diterpenoids [jatrophanes (1-6) and a tigliane (7)] were isolated and their structures elucidated by spectroscopic techniques. The biological activity of the new compounds was studied against four human cancer cell lines. The most effective jatrophane-type compound (2) and its structurally closely related derivative (1) were evaluated for their interactions with paclitaxel and doxorubicin using a multidrug-resistant cancer cell line. Both compounds exerted a strong reversal potential resulting from inhibition of P-glycoprotein transport.en
dc.publisherAmer Chemical Soc, Washington
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41031/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Natural Products
dc.titleIsolation and Biological Evaluation of Jatrophane Diterpenoids from Euphorbia dendroidesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractПесиц, Милица; Тодоровић, Нина; Банковиц, Јасна; Таниц, Никола; Руздијиц, Сабера; Вајс, Влатка Е.; Марковиц, Иванка Д.; Тесевиц, Веле В.; Aљанчић, Ивана С.; Милосављевиц, Слободан М.; Миосављевиц, Горан; Повреновиц, Драган; Јадранин, Милка;
dc.citation.volume74
dc.citation.issue7
dc.citation.spage1613
dc.citation.epage1620
dc.citation.other74(7): 1613-1620
dc.citation.rankM21
dc.identifier.pmid21707046
dc.identifier.doi10.1021/np200241c
dc.identifier.rcubConv_2336
dc.identifier.scopus2-s2.0-79960728011
dc.identifier.wos000293036100009
dc.type.versionpublishedVersion


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