Bioprospecting of Selected Species of Polypore Fungi from the Western Balkans
2024
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Аутори
Kozarski, MajaKlaus, Anita
Špirović Trifunović, Bojana
Miletić, Srđan
Lazić, Vesna
Žižak, Željko
Vunduk, Jovana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Growing mushrooms means meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Customized strains adapted to local conditions are urgently needed. Before introducing new species to the strain development pipeline, the chemical characterization and biological activity of wild ones need to be assessed. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated including: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and anti-angiotensin converting enzyme (ACE). The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lycopene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyr...osinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to normal cells. The evaluated species provided a solid foundation for commercial development while keeping local ecology in mind.
Кључне речи:
biological activity / bioprospecting / Coriolus / Fomitopsis / Ganoderma / mushroom cultivation / oxidative damage prevention / polyporeИзвор:
Molecules, 2024, 29, 2, 314-Издавач:
- MDPI
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200026 (Универзитет у Београду, Институт за хемију, технологију и металургију - ИХТМ) (RS-MESTD-inst-2020-200026)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200051 (Институт за општу и физичку хемију, Београд) (RS-MESTD-inst-2020-200051)
DOI: 10.3390/molecules29020314
ISSN: 1420-3049
PubMed: 38257227
WoS: 001152891000001
Scopus: 2-s2.0-85183253683
Институција/група
IHTMTY - JOUR AU - Kozarski, Maja AU - Klaus, Anita AU - Špirović Trifunović, Bojana AU - Miletić, Srđan AU - Lazić, Vesna AU - Žižak, Željko AU - Vunduk, Jovana PY - 2024 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/7297 AB - Growing mushrooms means meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Customized strains adapted to local conditions are urgently needed. Before introducing new species to the strain development pipeline, the chemical characterization and biological activity of wild ones need to be assessed. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated including: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and anti-angiotensin converting enzyme (ACE). The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lycopene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyrosinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to normal cells. The evaluated species provided a solid foundation for commercial development while keeping local ecology in mind. PB - MDPI T2 - Molecules T1 - Bioprospecting of Selected Species of Polypore Fungi from the Western Balkans VL - 29 IS - 2 SP - 314 DO - 10.3390/molecules29020314 ER -
@article{ author = "Kozarski, Maja and Klaus, Anita and Špirović Trifunović, Bojana and Miletić, Srđan and Lazić, Vesna and Žižak, Željko and Vunduk, Jovana", year = "2024", abstract = "Growing mushrooms means meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Customized strains adapted to local conditions are urgently needed. Before introducing new species to the strain development pipeline, the chemical characterization and biological activity of wild ones need to be assessed. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated including: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and anti-angiotensin converting enzyme (ACE). The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lycopene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyrosinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to normal cells. The evaluated species provided a solid foundation for commercial development while keeping local ecology in mind.", publisher = "MDPI", journal = "Molecules", title = "Bioprospecting of Selected Species of Polypore Fungi from the Western Balkans", volume = "29", number = "2", pages = "314", doi = "10.3390/molecules29020314" }
Kozarski, M., Klaus, A., Špirović Trifunović, B., Miletić, S., Lazić, V., Žižak, Ž.,& Vunduk, J.. (2024). Bioprospecting of Selected Species of Polypore Fungi from the Western Balkans. in Molecules MDPI., 29(2), 314. https://doi.org/10.3390/molecules29020314
Kozarski M, Klaus A, Špirović Trifunović B, Miletić S, Lazić V, Žižak Ž, Vunduk J. Bioprospecting of Selected Species of Polypore Fungi from the Western Balkans. in Molecules. 2024;29(2):314. doi:10.3390/molecules29020314 .
Kozarski, Maja, Klaus, Anita, Špirović Trifunović, Bojana, Miletić, Srđan, Lazić, Vesna, Žižak, Željko, Vunduk, Jovana, "Bioprospecting of Selected Species of Polypore Fungi from the Western Balkans" in Molecules, 29, no. 2 (2024):314, https://doi.org/10.3390/molecules29020314 . .