Modeling and Simulation of a TFET-Based Label-Free Biosensor with Enhanced Sensitivity
Аутори
Choudhury, SagarikaBaishnab, Krishna Lal
Guha, Koushik
Jakšić, Zoran
Jakšić, Olga
Iannacci, Jacopo
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This study discusses the use of a triple material gate (TMG) junctionless tunnel field-effect transistor (JLTFET) as a biosensor to identify different protein molecules. Among the plethora of existing types of biosensors, FET/TFET-based devices are fully compatible with conventional integrated circuits. JLTFETs are preferred over TFETs and JLFETs because of their ease of fabrication and superior biosensing performance. Biomolecules are trapped by cavities etched across the gates. An analytical mathematical model of a TMG asymmetrical hetero-dielectric JLTFET biosensor is derived here for the first time. The TCAD simulator is used to examine the performance of a dielectrically modulated label-free biosensor. The voltage and current sensitivity of the device and the effects of the cavity size, bioanalyte electric charge, fill factor, and location on the performance of the biosensor are also investigated. The relative current sensitivity of the biosensor is found to be about 1013. Besides... showing an enhanced sensitivity compared with other FET- and TFET-based biosensors, the device proves itself convenient for low-power applications, thus opening up numerous directions for future research and applications.
Кључне речи:
biosensors / protein sensing / tunnel field-effect transistor / TFET / junctionless TFET / triple material gate / TCAD simulationИзвор:
Chemosensors, 2023, 11, 5, 312-Издавач:
- MDPI
DOI: 10.3390/chemosensors11050312
ISSN: 2227-9040
WoS: 000997678300001
Scopus: 2-s2.0-85154570188
Институција/група
IHTMTY - JOUR AU - Choudhury, Sagarika AU - Baishnab, Krishna Lal AU - Guha, Koushik AU - Jakšić, Zoran AU - Jakšić, Olga AU - Iannacci, Jacopo PY - 2023 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/7205 AB - This study discusses the use of a triple material gate (TMG) junctionless tunnel field-effect transistor (JLTFET) as a biosensor to identify different protein molecules. Among the plethora of existing types of biosensors, FET/TFET-based devices are fully compatible with conventional integrated circuits. JLTFETs are preferred over TFETs and JLFETs because of their ease of fabrication and superior biosensing performance. Biomolecules are trapped by cavities etched across the gates. An analytical mathematical model of a TMG asymmetrical hetero-dielectric JLTFET biosensor is derived here for the first time. The TCAD simulator is used to examine the performance of a dielectrically modulated label-free biosensor. The voltage and current sensitivity of the device and the effects of the cavity size, bioanalyte electric charge, fill factor, and location on the performance of the biosensor are also investigated. The relative current sensitivity of the biosensor is found to be about 1013. Besides showing an enhanced sensitivity compared with other FET- and TFET-based biosensors, the device proves itself convenient for low-power applications, thus opening up numerous directions for future research and applications. PB - MDPI T2 - Chemosensors T1 - Modeling and Simulation of a TFET-Based Label-Free Biosensor with Enhanced Sensitivity VL - 11 IS - 5 SP - 312 DO - 10.3390/chemosensors11050312 ER -
@article{ author = "Choudhury, Sagarika and Baishnab, Krishna Lal and Guha, Koushik and Jakšić, Zoran and Jakšić, Olga and Iannacci, Jacopo", year = "2023", abstract = "This study discusses the use of a triple material gate (TMG) junctionless tunnel field-effect transistor (JLTFET) as a biosensor to identify different protein molecules. Among the plethora of existing types of biosensors, FET/TFET-based devices are fully compatible with conventional integrated circuits. JLTFETs are preferred over TFETs and JLFETs because of their ease of fabrication and superior biosensing performance. Biomolecules are trapped by cavities etched across the gates. An analytical mathematical model of a TMG asymmetrical hetero-dielectric JLTFET biosensor is derived here for the first time. The TCAD simulator is used to examine the performance of a dielectrically modulated label-free biosensor. The voltage and current sensitivity of the device and the effects of the cavity size, bioanalyte electric charge, fill factor, and location on the performance of the biosensor are also investigated. The relative current sensitivity of the biosensor is found to be about 1013. Besides showing an enhanced sensitivity compared with other FET- and TFET-based biosensors, the device proves itself convenient for low-power applications, thus opening up numerous directions for future research and applications.", publisher = "MDPI", journal = "Chemosensors", title = "Modeling and Simulation of a TFET-Based Label-Free Biosensor with Enhanced Sensitivity", volume = "11", number = "5", pages = "312", doi = "10.3390/chemosensors11050312" }
Choudhury, S., Baishnab, K. L., Guha, K., Jakšić, Z., Jakšić, O.,& Iannacci, J.. (2023). Modeling and Simulation of a TFET-Based Label-Free Biosensor with Enhanced Sensitivity. in Chemosensors MDPI., 11(5), 312. https://doi.org/10.3390/chemosensors11050312
Choudhury S, Baishnab KL, Guha K, Jakšić Z, Jakšić O, Iannacci J. Modeling and Simulation of a TFET-Based Label-Free Biosensor with Enhanced Sensitivity. in Chemosensors. 2023;11(5):312. doi:10.3390/chemosensors11050312 .
Choudhury, Sagarika, Baishnab, Krishna Lal, Guha, Koushik, Jakšić, Zoran, Jakšić, Olga, Iannacci, Jacopo, "Modeling and Simulation of a TFET-Based Label-Free Biosensor with Enhanced Sensitivity" in Chemosensors, 11, no. 5 (2023):312, https://doi.org/10.3390/chemosensors11050312 . .