Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation
2023
Преузимање 🢃
Аутори
Kozarski, MajaKlaus, Anita
Špirović Trifunović, Bojana
Miletić, Srđan
Lazić, Vesna
Žižak, Željko
Vunduk, Jovana
Препринт (Нерецензирана верзија)
Метаподаци
Приказ свих података о документуАпстракт
Growing mushrooms is meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Following the harvest, enormous quantities of spent mushroom substrate containing spores are disposed presenting a type of foreign material pressure on the ecosystem in the form of the loss of genetic diversity in wild mushroom populations. This challenge can be mitigated by bioprospecting local strains and using them to generate commercial inoculum. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and antiangiotensin converting enzyme (ACE) properties. The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lyco...pene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyrosinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to healthy cells. The evaluated species provided a solid foundation for commercial development while keeping the local ecology in mind.
Кључне речи:
biological activity / bioprospecting / Coriolus / Fomitopsis / Ganoderma / mushroom cultivation / oxidative damage prevention / PolyporeИзвор:
Preprints, 2023, 2023111765-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200026 (Универзитет у Београду, Институт за хемију, технологију и металургију - ИХТМ) (RS-MESTD-inst-2020-200026)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200051 (Институт за општу и физичку хемију, Београд) (RS-MESTD-inst-2020-200051)
Напомена:
- This is not peer-reviewed version.
- The supplementary information: https://cer.ihtm.bg.ac.rs/handle/123456789/7058
Повезане информације:
- Повезани садржај
https://cer.ihtm.bg.ac.rs/handle/123456789/7058 - Повезани садржај
https://europepmc.org/article/ppr/ppr766547
URI
https://www.preprints.org/manuscript/202311.1765/v1https://cer.ihtm.bg.ac.rs/handle/123456789/7057
Институција/група
IHTMTY - GEN AU - Kozarski, Maja AU - Klaus, Anita AU - Špirović Trifunović, Bojana AU - Miletić, Srđan AU - Lazić, Vesna AU - Žižak, Željko AU - Vunduk, Jovana PY - 2023 UR - https://www.preprints.org/manuscript/202311.1765/v1 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/7057 AB - Growing mushrooms is meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Following the harvest, enormous quantities of spent mushroom substrate containing spores are disposed presenting a type of foreign material pressure on the ecosystem in the form of the loss of genetic diversity in wild mushroom populations. This challenge can be mitigated by bioprospecting local strains and using them to generate commercial inoculum. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and antiangiotensin converting enzyme (ACE) properties. The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lycopene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyrosinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to healthy cells. The evaluated species provided a solid foundation for commercial development while keeping the local ecology in mind. T2 - Preprints T1 - Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation SP - 2023111765 DO - 10.20944/preprints202311.1765.v1 ER -
@misc{ author = "Kozarski, Maja and Klaus, Anita and Špirović Trifunović, Bojana and Miletić, Srđan and Lazić, Vesna and Žižak, Željko and Vunduk, Jovana", year = "2023", abstract = "Growing mushrooms is meeting challenges while aiming for sustainability and circularity. Wherever the producer is located, commercial strains are the same originating from several producers. Following the harvest, enormous quantities of spent mushroom substrate containing spores are disposed presenting a type of foreign material pressure on the ecosystem in the form of the loss of genetic diversity in wild mushroom populations. This challenge can be mitigated by bioprospecting local strains and using them to generate commercial inoculum. Accordingly, the mycoceutical potential of five polypore mushroom species from Serbia was evaluated: secondary metabolite composition, oxidative damage prevention, anti-tyrosinase, and antiangiotensin converting enzyme (ACE) properties. The phenolic pattern was comparable in all samples, but the amounts of specific chemicals varied. Hydroxybenzoic acids were the primary components. All samples had varying quantities of ascorbic acid, carotene, and lycopene, and showed a pronounced inhibition of lipid peroxidation (LPx) and ability to scavenge HO•. Extracts were more potent tyrosinase inhibitors but unsuccessful when faced with ACE. Fomitopsis pinicola had the strongest anti-tumor efficacy while Ganoderma lucidum demonstrated strong selectivity in anti-tumor effect in comparison to healthy cells. The evaluated species provided a solid foundation for commercial development while keeping the local ecology in mind.", journal = "Preprints", title = "Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation", pages = "2023111765", doi = "10.20944/preprints202311.1765.v1" }
Kozarski, M., Klaus, A., Špirović Trifunović, B., Miletić, S., Lazić, V., Žižak, Ž.,& Vunduk, J.. (2023). Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation. in Preprints, 2023111765. https://doi.org/10.20944/preprints202311.1765.v1
Kozarski M, Klaus A, Špirović Trifunović B, Miletić S, Lazić V, Žižak Ž, Vunduk J. Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation. in Preprints. 2023;:2023111765. doi:10.20944/preprints202311.1765.v1 .
Kozarski, Maja, Klaus, Anita, Špirović Trifunović, Bojana, Miletić, Srđan, Lazić, Vesna, Žižak, Željko, Vunduk, Jovana, "Identifying the Biological Potential of Western Balkan Polypore Mushroom Species to Mitigate the Negative Effects of Global Mushroom Cultivation" in Preprints (2023):2023111765, https://doi.org/10.20944/preprints202311.1765.v1 . .