Приказ основних података о документу
The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7
dc.creator | Konstantinović, Sandra S. | |
dc.creator | Zlatkovic, Milica Z. | |
dc.creator | Ciric, Jovan T. | |
dc.creator | Ilić, Slavica B. | |
dc.creator | Gojgić-Cvijović, Gordana | |
dc.creator | Veljković, Vlada B. | |
dc.date.accessioned | 2019-01-30T17:53:30Z | |
dc.date.available | 2019-01-30T17:53:30Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 0367-598X | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/2102 | |
dc.description.abstract | In the present work, four derivatives of salicylaldehyde (salicylaldehyde-hydrazone, phenylhydrazone, semicarbazone and thiosemicarbazone) were synthesized using both conventional (95% ethanol) and green (crude glycerol from biodiesel production) solvents. The obtained compounds were identified by elemental microanalysis, as well as FTIR, UV/Vis and H-1-NMR spectroscopic methods. Yields of 93-98% of the compounds in crude glycerol were achieved within 10-25 min. The derivatives of salicylaldehyde and crude glycerol were used as a nitrogen and carbon source, respectively, in the medium for antibiotic (hexaene H-85 and azalomycine B) production by Streptomyces hygroscopicus CH-7. The highest concentrations of hexaene H-85 and azalomycine B were achieved in the medium containing salicylaldehyde-thiosemicarbazone (198 and 69 mu g/cm(3), respectively). Derivatives of salicylaldehyde also impacted the strain morphology. In the media with salicylaldehyde- phenylhydrazone and salicylaldehyde-thiosemicarbazone, S. hygroscopicus CH-7 grew like large dispersive pellets with long twisted filaments that produced the highest yield of the antibiotics. | en |
dc.publisher | Association of Chemical Engineers of Serbia | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45001/RS// | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Hemijska industrija | |
dc.subject | glycerol | en |
dc.subject | salicylaldehyde | en |
dc.subject | Streptomyces | en |
dc.subject | antibiotic | en |
dc.subject | morphology | en |
dc.title | The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7 | en |
dc.type | article | |
dc.rights.license | BY-NC-ND | |
dcterms.abstract | Вељковиц, Влада Б.; Златковиц, Милица З.; Цириц, Јован Т.; Илиц, Славица Б.; Константиновиц, Сандра С.; Гојгић Цвијовић, Гордана; | |
dc.citation.volume | 71 | |
dc.citation.issue | 6 | |
dc.citation.spage | 487 | |
dc.citation.epage | 494 | |
dc.citation.other | 71(6): 487-494 | |
dc.citation.rank | M23 | |
dc.identifier.doi | 10.2298/HEMIND170124011K | |
dc.identifier.fulltext | https://cer.ihtm.bg.ac.rs//bitstream/id/8530/2100.pdf | |
dc.identifier.scopus | 2-s2.0-85044395363 | |
dc.identifier.wos | 000419973400004 | |
dc.type.version | publishedVersion |