The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7
2017
Autori
Konstantinović, Sandra S.Zlatkovic, Milica Z.
Ciric, Jovan T.
Ilić, Slavica B.
Gojgić-Cvijović, Gordana
Veljković, Vlada B.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
In the present work, four derivatives of salicylaldehyde (salicylaldehyde-hydrazone, phenylhydrazone, semicarbazone and thiosemicarbazone) were synthesized using both conventional (95% ethanol) and green (crude glycerol from biodiesel production) solvents. The obtained compounds were identified by elemental microanalysis, as well as FTIR, UV/Vis and H-1-NMR spectroscopic methods. Yields of 93-98% of the compounds in crude glycerol were achieved within 10-25 min. The derivatives of salicylaldehyde and crude glycerol were used as a nitrogen and carbon source, respectively, in the medium for antibiotic (hexaene H-85 and azalomycine B) production by Streptomyces hygroscopicus CH-7. The highest concentrations of hexaene H-85 and azalomycine B were achieved in the medium containing salicylaldehyde-thiosemicarbazone (198 and 69 mu g/cm(3), respectively). Derivatives of salicylaldehyde also impacted the strain morphology. In the media with salicylaldehyde- phenylhydrazone and salicylaldehyde-t...hiosemicarbazone, S. hygroscopicus CH-7 grew like large dispersive pellets with long twisted filaments that produced the highest yield of the antibiotics.
Ključne reči:
glycerol / salicylaldehyde / Streptomyces / antibiotic / morphologyIzvor:
Hemijska industrija, 2017, 71, 6, 487-494Izdavač:
- Association of Chemical Engineers of Serbia
Finansiranje / projekti:
- Nanostrukturni funkcionalni i kompozitni materijali u katalitičkim i sorpcionim procesima (RS-45001)
DOI: 10.2298/HEMIND170124011K
ISSN: 0367-598X
WoS: 000419973400004
Scopus: 2-s2.0-85044395363
Institucija/grupa
IHTMTY - JOUR AU - Konstantinović, Sandra S. AU - Zlatkovic, Milica Z. AU - Ciric, Jovan T. AU - Ilić, Slavica B. AU - Gojgić-Cvijović, Gordana AU - Veljković, Vlada B. PY - 2017 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2102 AB - In the present work, four derivatives of salicylaldehyde (salicylaldehyde-hydrazone, phenylhydrazone, semicarbazone and thiosemicarbazone) were synthesized using both conventional (95% ethanol) and green (crude glycerol from biodiesel production) solvents. The obtained compounds were identified by elemental microanalysis, as well as FTIR, UV/Vis and H-1-NMR spectroscopic methods. Yields of 93-98% of the compounds in crude glycerol were achieved within 10-25 min. The derivatives of salicylaldehyde and crude glycerol were used as a nitrogen and carbon source, respectively, in the medium for antibiotic (hexaene H-85 and azalomycine B) production by Streptomyces hygroscopicus CH-7. The highest concentrations of hexaene H-85 and azalomycine B were achieved in the medium containing salicylaldehyde-thiosemicarbazone (198 and 69 mu g/cm(3), respectively). Derivatives of salicylaldehyde also impacted the strain morphology. In the media with salicylaldehyde- phenylhydrazone and salicylaldehyde-thiosemicarbazone, S. hygroscopicus CH-7 grew like large dispersive pellets with long twisted filaments that produced the highest yield of the antibiotics. PB - Association of Chemical Engineers of Serbia T2 - Hemijska industrija T1 - The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7 VL - 71 IS - 6 SP - 487 EP - 494 DO - 10.2298/HEMIND170124011K ER -
@article{ author = "Konstantinović, Sandra S. and Zlatkovic, Milica Z. and Ciric, Jovan T. and Ilić, Slavica B. and Gojgić-Cvijović, Gordana and Veljković, Vlada B.", year = "2017", abstract = "In the present work, four derivatives of salicylaldehyde (salicylaldehyde-hydrazone, phenylhydrazone, semicarbazone and thiosemicarbazone) were synthesized using both conventional (95% ethanol) and green (crude glycerol from biodiesel production) solvents. The obtained compounds were identified by elemental microanalysis, as well as FTIR, UV/Vis and H-1-NMR spectroscopic methods. Yields of 93-98% of the compounds in crude glycerol were achieved within 10-25 min. The derivatives of salicylaldehyde and crude glycerol were used as a nitrogen and carbon source, respectively, in the medium for antibiotic (hexaene H-85 and azalomycine B) production by Streptomyces hygroscopicus CH-7. The highest concentrations of hexaene H-85 and azalomycine B were achieved in the medium containing salicylaldehyde-thiosemicarbazone (198 and 69 mu g/cm(3), respectively). Derivatives of salicylaldehyde also impacted the strain morphology. In the media with salicylaldehyde- phenylhydrazone and salicylaldehyde-thiosemicarbazone, S. hygroscopicus CH-7 grew like large dispersive pellets with long twisted filaments that produced the highest yield of the antibiotics.", publisher = "Association of Chemical Engineers of Serbia", journal = "Hemijska industrija", title = "The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7", volume = "71", number = "6", pages = "487-494", doi = "10.2298/HEMIND170124011K" }
Konstantinović, S. S., Zlatkovic, M. Z., Ciric, J. T., Ilić, S. B., Gojgić-Cvijović, G.,& Veljković, V. B.. (2017). The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7. in Hemijska industrija Association of Chemical Engineers of Serbia., 71(6), 487-494. https://doi.org/10.2298/HEMIND170124011K
Konstantinović SS, Zlatkovic MZ, Ciric JT, Ilić SB, Gojgić-Cvijović G, Veljković VB. The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7. in Hemijska industrija. 2017;71(6):487-494. doi:10.2298/HEMIND170124011K .
Konstantinović, Sandra S., Zlatkovic, Milica Z., Ciric, Jovan T., Ilić, Slavica B., Gojgić-Cvijović, Gordana, Veljković, Vlada B., "The use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7" in Hemijska industrija, 71, no. 6 (2017):487-494, https://doi.org/10.2298/HEMIND170124011K . .