Development and validation of an LC-MS/MS method with a multiple reactions monitoring mode for the quantification of vanillin and syringaldehyde in plum brandies
2014
Аутори
Tešević, VeleAljančić, Ivana
Vajs, Vlatka
Živković, Marijana
Nikićević, Ninoslav
Urosevic, Ivan
Vujisić, Ljubodrag V.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
An ultra-performance liquid chromatographic triple quadrupole mass spectrometric (UPLC-QqQ-MS/MS) method with a multiple reactions monitoring mode (MRM) was developed and validated for the quantification of vanillin and syringaldehyde in plum brandy. The method showed good linearity (0.05 to 10 mg L-1) and low limits of detection and quantification (the LOD and LOQ values were 11.6 and 38.2 mu g L-1 for vanillin, and 12.7 and 42.0 mu g L-1 for syringaldehyde, respectively). The overall intra-day and inter-day variations were less than 4.21 % and the overall recovery was over 93.0 %. The correlation coefficients (R-2) of the calibration curves were higher than 0.9999. In order to evaluate whether the method was suitable for use as a routine analytical tool, vanillin and syringaldehyde were determined in 31 samples of Serbian plum brandy.
Кључне речи:
vanillin / syringaldehyde / plum brandy / LC-MS/MSИзвор:
Journal of the Serbian Chemical Society, 2014, 79, 12, 1537-1543Издавач:
- Serbian Chemical Soc, Belgrade
Финансирање / пројекти:
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-MESTD-Basic Research (BR or ON)-172053)
DOI: 10.2298/JSC140225079T
ISSN: 0352-5139
WoS: 000348749400008
Scopus: 2-s2.0-84920836911
Институција/група
IHTMTY - JOUR AU - Tešević, Vele AU - Aljančić, Ivana AU - Vajs, Vlatka AU - Živković, Marijana AU - Nikićević, Ninoslav AU - Urosevic, Ivan AU - Vujisić, Ljubodrag V. PY - 2014 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/1489 AB - An ultra-performance liquid chromatographic triple quadrupole mass spectrometric (UPLC-QqQ-MS/MS) method with a multiple reactions monitoring mode (MRM) was developed and validated for the quantification of vanillin and syringaldehyde in plum brandy. The method showed good linearity (0.05 to 10 mg L-1) and low limits of detection and quantification (the LOD and LOQ values were 11.6 and 38.2 mu g L-1 for vanillin, and 12.7 and 42.0 mu g L-1 for syringaldehyde, respectively). The overall intra-day and inter-day variations were less than 4.21 % and the overall recovery was over 93.0 %. The correlation coefficients (R-2) of the calibration curves were higher than 0.9999. In order to evaluate whether the method was suitable for use as a routine analytical tool, vanillin and syringaldehyde were determined in 31 samples of Serbian plum brandy. PB - Serbian Chemical Soc, Belgrade T2 - Journal of the Serbian Chemical Society T1 - Development and validation of an LC-MS/MS method with a multiple reactions monitoring mode for the quantification of vanillin and syringaldehyde in plum brandies VL - 79 IS - 12 SP - 1537 EP - 1543 DO - 10.2298/JSC140225079T ER -
@article{ author = "Tešević, Vele and Aljančić, Ivana and Vajs, Vlatka and Živković, Marijana and Nikićević, Ninoslav and Urosevic, Ivan and Vujisić, Ljubodrag V.", year = "2014", abstract = "An ultra-performance liquid chromatographic triple quadrupole mass spectrometric (UPLC-QqQ-MS/MS) method with a multiple reactions monitoring mode (MRM) was developed and validated for the quantification of vanillin and syringaldehyde in plum brandy. The method showed good linearity (0.05 to 10 mg L-1) and low limits of detection and quantification (the LOD and LOQ values were 11.6 and 38.2 mu g L-1 for vanillin, and 12.7 and 42.0 mu g L-1 for syringaldehyde, respectively). The overall intra-day and inter-day variations were less than 4.21 % and the overall recovery was over 93.0 %. The correlation coefficients (R-2) of the calibration curves were higher than 0.9999. In order to evaluate whether the method was suitable for use as a routine analytical tool, vanillin and syringaldehyde were determined in 31 samples of Serbian plum brandy.", publisher = "Serbian Chemical Soc, Belgrade", journal = "Journal of the Serbian Chemical Society", title = "Development and validation of an LC-MS/MS method with a multiple reactions monitoring mode for the quantification of vanillin and syringaldehyde in plum brandies", volume = "79", number = "12", pages = "1537-1543", doi = "10.2298/JSC140225079T" }
Tešević, V., Aljančić, I., Vajs, V., Živković, M., Nikićević, N., Urosevic, I.,& Vujisić, L. V.. (2014). Development and validation of an LC-MS/MS method with a multiple reactions monitoring mode for the quantification of vanillin and syringaldehyde in plum brandies. in Journal of the Serbian Chemical Society Serbian Chemical Soc, Belgrade., 79(12), 1537-1543. https://doi.org/10.2298/JSC140225079T
Tešević V, Aljančić I, Vajs V, Živković M, Nikićević N, Urosevic I, Vujisić LV. Development and validation of an LC-MS/MS method with a multiple reactions monitoring mode for the quantification of vanillin and syringaldehyde in plum brandies. in Journal of the Serbian Chemical Society. 2014;79(12):1537-1543. doi:10.2298/JSC140225079T .
Tešević, Vele, Aljančić, Ivana, Vajs, Vlatka, Živković, Marijana, Nikićević, Ninoslav, Urosevic, Ivan, Vujisić, Ljubodrag V., "Development and validation of an LC-MS/MS method with a multiple reactions monitoring mode for the quantification of vanillin and syringaldehyde in plum brandies" in Journal of the Serbian Chemical Society, 79, no. 12 (2014):1537-1543, https://doi.org/10.2298/JSC140225079T . .