Приказ основних података о документу

dc.creatorAvramov Ivić, Milka
dc.creatorStoiljković, Zora
dc.creatorJovanović, Vladislava M.
dc.creatorMijin, Dušan
dc.creatorNikolić, V.
dc.creatorNikolić, L.j.
dc.creatorPetrović, Slobodan D.
dc.date.accessioned2019-01-30T17:38:27Z
dc.date.available2019-01-30T17:38:27Z
dc.date.issued2013
dc.identifier.issn1452-3981
dc.identifier.urihttps://cer.ihtm.bg.ac.rs/handle/123456789/1382
dc.description.abstractThe electrochemical behavior of inclusion complexes of nifedipine (Nif) and amlodipine (Aml), a long-acting calcium channel blockers dihydropyridine (DHP) class, with ß-cyclodextrin (ßCD) and (2-hydroxypropyl)-ß-cyclodextrin (HPßCD), is examined using cyclic and square wave voltammetry in 0.05 M NaHCO3 and phosphate buffer (pH=11) on a gold electrode. The voltammograms show a single irreversible anodic wave with the current controlled by adsorption. It was found that phosphate buffer favorites the electrochemical activity of both complexes of Nif with the linear dependency of the oxidative currents on their concentrations. In phosphate buffer, only HPßCD-Aml complex showed linear dependency of the oxidative currents on the concentration. In 0.05 M NaHCO3 as electrolyte only HPßCD-Nif exhibited apparent activity. The initial potential of the anodic reaction as well as the value of the potential for anodic currents maximum of all the examined complexes in both electrolytes were shifted to the positive direction compared to their standards. In addition, the value of anodic currents decreased.en
dc.publisherEsg, Belgrade
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172013/RS//
dc.rightsopenAccess
dc.sourceInternational Journal of Electrochemical Science
dc.subjectCyclic voltammetryen
dc.subjectcyclodextrin complexesen
dc.subjectElectrochemical determinationen
dc.subjectGold electrodeen
dc.subjectSquare wave voltammetryen
dc.titleThe electrochemical investigation of inclusion complexes of nifedipine and amlodipine with ß-cyclodextrin and (2-hydroxypropyl)-ß-cyclodextrinen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractНиколић, Л.ј.; Стоиљковић, З.З.; Мијин, Д.Ж.; Николић, В.; Aврамов Ивић, Милка; Јовановић, Владислава; Петровић, Слободан Д.;
dc.citation.volume8
dc.citation.issue7
dc.citation.spage9543
dc.citation.epage9557
dc.citation.other8(7): 9543-9557
dc.citation.rankM22
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_cer_1382
dc.identifier.fulltexthttps://cer.ihtm.bg.ac.rs/bitstream/id/14927/80709543.pdf
dc.identifier.scopus2-s2.0-84881578068
dc.type.versionpublishedVersion


Документи

Thumbnail

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу