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Synthesis of Orthogonally Protected (+/-)-3-Amino-4-anilidopiperidines and (+/-)-3-N-Carbomethoxyfentanyl
(Georg Thieme Verlag Kg, Stuttgart, 2017)
The synthesis of orthogonally protected cis- and trans-3-amino-4-anilidopiperidine derivatives has been accomplished in six steps, starting from readily accessible 4-piperidone derivatives. The last three steps, i.e., ...
Proteomics and Peptidomics as Tools for Detection of Food Contamination by Bacteria
(John Wiley & Sons, Ltd, 2017)
Proteomics and peptidomics are key foodomic techniques that are indispensable for monitoring of pathogen contamination in foods during their production, storage and transportation, up to their consumption. The thick ...
Protein and Peptide Separations
(Elsevier, 2017)
Since the introduction of suitable, highly porous supports and later nonporous and monolithic supports, chromatography has been an indispensibleindispensable method for protein separations on the analytical and preparative ...
Removal of alprazolam from aqueous solutions by heterogeneous photocatalysis: Influencing factors, intermediates, and products
(Elsevier Science Sa, Lausanne, 2017)
Efficiency of heterogeneous photocatalytic degradation of aiprazolam was investigated. The structural and morphological properties of ZnO were investigated in detail. It was found that ZnO has wurtzite structure with ...
Tailor-made biocatalysts based on scarcely studied acidic horseradish peroxidase for biodegradation of reactive dyes
(Springer Heidelberg, Heidelberg, 2017)
Peroxidases (EC 1.11.1.7) have enormous biotechnological applications. Usage of more abundant, basic isoforms of peroxidases in diagnostic kits and/or in immunochemistry has led to under exploitation and disregard of ...
Influence of Nafion on detection of glucose on a polycrystalline gold electrode from alkaline and saline solutions
(Springer Heidelberg, Heidelberg, 2017)
The electrooxidation of glucose on a polycrystalline gold electrode from alkaline and saline solutions was investigated. The influence of Nafion on the oxidation of glucose under the same conditions was also studied. The ...
Consensus-based comparison of chromatographic and computationally estimated lipophilicity of benzothiepino[3,2-c]pyridine derivatives as potential antifungal drugs
(Wiley-V C H Verlag Gmbh, Weinheim, 2017)
Lipophilicity is one of the essential properties influencing drug absorption, excretion and metabolism. It is used for screening viable drug candidates. Chromatographic behavior of thiepino[3,2-c: 6,7-c'] dipyridine and ...
Individual effects of different selenocompounds on the hepatic proteome and energy metabolism of mice
(Elsevier, 2017)
Background: Selenium (Se) exerts its biological activity largely via selenoproteins, which are key enzymes for maintaining the cellular redox homeostasis. However, besides these beneficial effects there is also evidence ...
Density functional theory modeling of C-Au chemical bond formation in gold implanted polyethylene
(Royal Soc Chemistry, Cambridge, 2017)
We have studied processes of gold ion implantation in polyethylene (PE) by theoretical chemistry methods. Car-Parrinello molecular dynamics (CPMD) simulations of collisions and following chemical kinetics considerations ...
Examination of the antimalarial potential of experimental aminoquinolines: poor in vitro effect does not preclude in vivo efficacy
(Elsevier, 2017)
Malaria remains a major disease in the developing world and globally is the most important parasitic disease causing significant morbidity and mortality. Because of widespread resistance to conventional antimalarials, ...